Alternative activation of macrophages by IL-4 impairs phagocytosis of pathogens but potentiates microbial-induced signalling and cytokine secretion

Blood

Volumn 115, Issue 2, 2010, Pages 353-362

  Varin, Audrey ^a   Mukhopadhyay, Subhankar ^a   Herbein, Georges ^b   Gordon, Siamon ^a,c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY HOSPITAL OF BESANÇON   (France)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOPHAGE RECEPTOR; BACTERIOPHAGE RECEPTOR MARCO; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN KINASE B; PROTEIN P42; PROTEIN P44; SCAVENGER RECEPTOR A; THIOGLYCOLIC ACID; UNCLASSIFIED DRUG; ZYMOSAN; CELL SURFACE RECEPTOR; IL4RA PROTEIN, MOUSE; IMMUNOGLOBULIN RECEPTOR; MARCO PROTEIN, MOUSE; MYD88 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; MACROPHAGE ACTIVATION; MOUSE; NEISSERIA MENINGITIDIS; NONHUMAN; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PHAGOSOME; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING; ANIMAL; DRUG EFFECT; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; PHOSPHORYLATION; SECRETION; SIGNAL TRANSDUCTION; TH2 CELL; TIME;

ANIMALS; INTERLEUKIN-13; INTERLEUKIN-4; MACROPHAGE ACTIVATION; MACROPHAGES, PERITONEAL; MICE; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; NEISSERIA MENINGITIDIS, SEROGROUP B; PHAGOCYTOSIS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; SIGNAL TRANSDUCTION; TH2 CELLS; TIME FACTORS;

EID: 75649097879     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-08-236711     Document Type: Article

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