메뉴 건너뛰기




Volumn 33, Issue 5, 2010, Pages 699-712

STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 4; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STAT6 PROTEIN;

EID: 78649388701     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2010.11.009     Document Type: Article
Times cited : (348)

References (43)
  • 4
    • 0242361567 scopus 로고    scopus 로고
    • Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism
    • Castrillo A., Joseph S.B., Vaidya S.A., Haberland M., Fogelman A.M., Cheng G., Tontonoz P. Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism. Mol. Cell 2003, 12:805-816.
    • (2003) Mol. Cell , vol.12 , pp. 805-816
    • Castrillo, A.1    Joseph, S.B.2    Vaidya, S.A.3    Haberland, M.4    Fogelman, A.M.5    Cheng, G.6    Tontonoz, P.7
  • 6
    • 0031573611 scopus 로고    scopus 로고
    • In vivo effects of T helper cell type 2 cytokines on macrophage antigen-presenting cell induction of T helper subsets
    • Cua D.J., Stohlman S.A. In vivo effects of T helper cell type 2 cytokines on macrophage antigen-presenting cell induction of T helper subsets. J. Immunol. 1997, 159:5834-5840.
    • (1997) J. Immunol. , vol.159 , pp. 5834-5840
    • Cua, D.J.1    Stohlman, S.A.2
  • 7
    • 0037071397 scopus 로고    scopus 로고
    • Transcriptional regulation of granulocyte and monocyte development
    • Friedman A.D. Transcriptional regulation of granulocyte and monocyte development. Oncogene 2002, 21:3377-3390.
    • (2002) Oncogene , vol.21 , pp. 3377-3390
    • Friedman, A.D.1
  • 9
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon S. Alternative activation of macrophages. Nat. Rev. Immunol. 2003, 3:23-35.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 23-35
    • Gordon, S.1
  • 11
    • 0034643803 scopus 로고    scopus 로고
    • Analysis of gene expression profile during 3T3-L1 preadipocyte differentiation
    • Guo X., Liao K. Analysis of gene expression profile during 3T3-L1 preadipocyte differentiation. Gene 2000, 251:45-53.
    • (2000) Gene , vol.251 , pp. 45-53
    • Guo, X.1    Liao, K.2
  • 12
    • 9144229185 scopus 로고    scopus 로고
    • Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle
    • He W., Barak Y., Hevener A., Olson P., Liao D., Le J., Nelson M., Ong E., Olefsky J.M., Evans R.M. Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle. Proc. Natl. Acad. Sci. USA 2003, 100:15712-15717.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 15712-15717
    • He, W.1    Barak, Y.2    Hevener, A.3    Olson, P.4    Liao, D.5    Le, J.6    Nelson, M.7    Ong, E.8    Olefsky, J.M.9    Evans, R.M.10
  • 15
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
    • Jiang C., Ting A.T., Seed B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 1998, 391:82-86.
    • (1998) Nature , vol.391 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 18
    • 0030985318 scopus 로고    scopus 로고
    • Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay
    • Krey G., Braissant O., L'Horset F., Kalkhoven E., Perroud M., Parker M.G., Wahli W. Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay. Mol. Endocrinol. 1997, 11:779-791.
    • (1997) Mol. Endocrinol. , vol.11 , pp. 779-791
    • Krey, G.1    Braissant, O.2    L'Horset, F.3    Kalkhoven, E.4    Perroud, M.5    Parker, M.G.6    Wahli, W.7
  • 19
    • 23844485897 scopus 로고    scopus 로고
    • From the Cover: Location analysis of estrogen receptor alpha target promoters reveals that FOXA1 defines a domain of the estrogen response
    • Laganière J., Deblois G., Lefebvre C., Bataille A.R., Robert F., Giguère V. From the Cover: Location analysis of estrogen receptor alpha target promoters reveals that FOXA1 defines a domain of the estrogen response. Proc. Natl. Acad. Sci. USA 2005, 102:11651-11656.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 11651-11656
    • Laganière, J.1    Deblois, G.2    Lefebvre, C.3    Bataille, A.R.4    Robert, F.5    Giguère, V.6
  • 21
    • 0034121698 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene
    • Li M., Pascual G., Glass C.K. Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene. Mol. Cell. Biol. 2000, 20:4699-4707.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 4699-4707
    • Li, M.1    Pascual, G.2    Glass, C.K.3
  • 22
    • 64749086158 scopus 로고    scopus 로고
    • Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPARgamma-/-, PPARdelta-/-, PPARgammadelta-/-, or LXRalphabeta-/- bone marrow
    • Marathe C., Bradley M.N., Hong C., Chao L., Wilpitz D., Salazar J., Tontonoz P. Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPARgamma-/-, PPARdelta-/-, PPARgammadelta-/-, or LXRalphabeta-/- bone marrow. J. Lipid Res. 2009, 50:214-224.
    • (2009) J. Lipid Res. , vol.50 , pp. 214-224
    • Marathe, C.1    Bradley, M.N.2    Hong, C.3    Chao, L.4    Wilpitz, D.5    Salazar, J.6    Tontonoz, P.7
  • 24
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
    • Nagy L., Tontonoz P., Alvarez J.G., Chen H., Evans R.M. Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell 1998, 93:229-240.
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3    Chen, H.4    Evans, R.M.5
  • 25
    • 70350087559 scopus 로고    scopus 로고
    • STAT5 regulation of BCL10 parallels constitutive NFkappaB activation in lymphoid tumor cells
    • Nagy Z.S., LeBaron M.J., Ross J.A., Mitra A., Rui H., Kirken R.A. STAT5 regulation of BCL10 parallels constitutive NFkappaB activation in lymphoid tumor cells. Mol. Cancer 2009, 8:67.
    • (2009) Mol. Cancer , vol.8 , pp. 67
    • Nagy, Z.S.1    LeBaron, M.J.2    Ross, J.A.3    Mitra, A.4    Rui, H.5    Kirken, R.A.6
  • 26
    • 0036681640 scopus 로고    scopus 로고
    • Dendritic cell immunogenicity is regulated by peroxisome proliferator-activated receptor gamma
    • Nencioni A., Grünebach F., Zobywlaski A., Denzlinger C., Brugger W., Brossart P. Dendritic cell immunogenicity is regulated by peroxisome proliferator-activated receptor gamma. J. Immunol. 2002, 169:1228-1235.
    • (2002) J. Immunol. , vol.169 , pp. 1228-1235
    • Nencioni, A.1    Grünebach, F.2    Zobywlaski, A.3    Denzlinger, C.4    Brugger, W.5    Brossart, P.6
  • 27
    • 55749101777 scopus 로고    scopus 로고
    • Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis
    • Nielsen R., Pedersen T.A., Hagenbeek D., Moulos P., Siersbaek R., Megens E., Denissov S., Børgesen M., Francoijs K.J., Mandrup S., Stunnenberg H.G. Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis. Genes Dev. 2008, 22:2953-2967.
    • (2008) Genes Dev. , vol.22 , pp. 2953-2967
    • Nielsen, R.1    Pedersen, T.A.2    Hagenbeek, D.3    Moulos, P.4    Siersbaek, R.5    Megens, E.6    Denissov, S.7    Børgesen, M.8    Francoijs, K.J.9    Mandrup, S.10    Stunnenberg, H.G.11
  • 29
    • 33748702268 scopus 로고    scopus 로고
    • Nuclear receptors versus inflammation: Mechanisms of transrepression
    • Pascual G., Glass C.K. Nuclear receptors versus inflammation: Mechanisms of transrepression. Trends Endocrinol. Metab. 2006, 17:321-327.
    • (2006) Trends Endocrinol. Metab. , vol.17 , pp. 321-327
    • Pascual, G.1    Glass, C.K.2
  • 31
    • 0029081822 scopus 로고
    • The CD1 family: A third lineage of antigen-presenting molecules
    • Porcelli S.A. The CD1 family: A third lineage of antigen-presenting molecules. Adv. Immunol. 1995, 59:1-98.
    • (1995) Adv. Immunol. , vol.59 , pp. 1-98
    • Porcelli, S.A.1
  • 32
    • 0032560545 scopus 로고    scopus 로고
    • Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein
    • Ricote M., Huang J., Fajas L., Li A., Welch J., Najib J., Witztum J.L., Auwerx J., Palinski W., Glass C.K. Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein. Proc. Natl. Acad. Sci. USA 1998, 95:7614-7619.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7614-7619
    • Ricote, M.1    Huang, J.2    Fajas, L.3    Li, A.4    Welch, J.5    Najib, J.6    Witztum, J.L.7    Auwerx, J.8    Palinski, W.9    Glass, C.K.10
  • 33
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • Ricote M., Li A.C., Willson T.M., Kelly C.J., Glass C.K. The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation. Nature 1998, 391:79-82.
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 34
    • 0026762988 scopus 로고
    • Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation
    • Stein M., Keshav S., Harris N., Gordon S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: A marker of alternative immunologic macrophage activation. J. Exp. Med. 1992, 176:287-292.
    • (1992) J. Exp. Med. , vol.176 , pp. 287-292
    • Stein, M.1    Keshav, S.2    Harris, N.3    Gordon, S.4
  • 35
    • 0018741501 scopus 로고
    • Identification of a novel cell type in peripheral lymphoid organs of mice. V. Purification of spleen dendritic cells, new surface markers, and maintenance in vitro
    • Steinman R.M., Kaplan G., Witmer M.D., Cohn Z.A. Identification of a novel cell type in peripheral lymphoid organs of mice. V. Purification of spleen dendritic cells, new surface markers, and maintenance in vitro. J. Exp. Med. 1979, 149:1-16.
    • (1979) J. Exp. Med. , vol.149 , pp. 1-16
    • Steinman, R.M.1    Kaplan, G.2    Witmer, M.D.3    Cohn, Z.A.4
  • 36
    • 21744458442 scopus 로고    scopus 로고
    • Retinoids potentiate peroxisome proliferator-activated receptor gamma action in differentiation, gene expression, and lipid metabolic processes in developing myeloid cells
    • Szanto A., Nagy L. Retinoids potentiate peroxisome proliferator-activated receptor gamma action in differentiation, gene expression, and lipid metabolic processes in developing myeloid cells. Mol. Pharmacol. 2005, 67:1935-1943.
    • (2005) Mol. Pharmacol. , vol.67 , pp. 1935-1943
    • Szanto, A.1    Nagy, L.2
  • 37
    • 3142688053 scopus 로고    scopus 로고
    • Activation of PPARgamma specifies a dendritic cell subtype capable of enhanced induction of iNKT cell expansion
    • Szatmari I., Gogolak P., Im J.S., Dezso B., Rajnavolgyi E., Nagy L. Activation of PPARgamma specifies a dendritic cell subtype capable of enhanced induction of iNKT cell expansion. Immunity 2004, 21:95-106.
    • (2004) Immunity , vol.21 , pp. 95-106
    • Szatmari, I.1    Gogolak, P.2    Im, J.S.3    Dezso, B.4    Rajnavolgyi, E.5    Nagy, L.6
  • 38
  • 41
    • 0032540012 scopus 로고    scopus 로고
    • PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
    • Tontonoz P., Nagy L., Alvarez J.G., Thomazy V.A., Evans R.M. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 1998, 93:241-252.
    • (1998) Cell , vol.93 , pp. 241-252
    • Tontonoz, P.1    Nagy, L.2    Alvarez, J.G.3    Thomazy, V.A.4    Evans, R.M.5
  • 42
    • 0038460253 scopus 로고    scopus 로고
    • PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages
    • Welch J.S., Ricote M., Akiyama T.E., Gonzalez F.J., Glass C.K. PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages. Proc. Natl. Acad. Sci. USA 2003, 100:6712-6717.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 6712-6717
    • Welch, J.S.1    Ricote, M.2    Akiyama, T.E.3    Gonzalez, F.J.4    Glass, C.K.5
  • 43
    • 0028244396 scopus 로고
    • Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells
    • Witthuhn B.A., Silvennoinen O., Miura O., Lai K.S., Cwik C., Liu E.T., Ihle J.N. Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells. Nature 1994, 370:153-157.
    • (1994) Nature , vol.370 , pp. 153-157
    • Witthuhn, B.A.1    Silvennoinen, O.2    Miura, O.3    Lai, K.S.4    Cwik, C.5    Liu, E.T.6    Ihle, J.N.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.