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Volumn 98, Issue 4, 2015, Pages 539-548

Neutrophil homeostasis and inflammation: Novel paradigms from studying periodontitis

Author keywords

Complement; Del 1; IL 17; Integrins; Leukocyte adhesion deficiency

Indexed keywords

CD18 ANTIGEN; INTERLEUKIN 17;

EID: 84943157037     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.3VMR1014-468R     Document Type: Review
Times cited : (102)

References (106)
  • 1
    • 84905085524 scopus 로고    scopus 로고
    • Social networking of human neutrophils within the immune system
    • Scapini, P., Cassatella, M. A. (2014) Social networking of human neutrophils within the immune system. Blood 124, 710-719
    • (2014) Blood , vol.124 , pp. 710-719
    • Scapini, P.1    Cassatella, M.A.2
  • 2
    • 84875580498 scopus 로고    scopus 로고
    • Neutrophil heterogeneity in health and disease: A revitalized avenue in inflammation and immunity
    • 120134
    • Beyrau, M., Bodkin, J. V., Nourshargh, S. (2012) Neutrophil heterogeneity in health and disease: a revitalized avenue in inflammation and immunity. Open Biol. 2, 120134
    • (2012) Open Biol , vol.2
    • Beyrau, M.1    Bodkin, J.V.2    Nourshargh, S.3
  • 3
    • 84880676381 scopus 로고    scopus 로고
    • Diverse novel functions of neutrophils in immunity, inflammation, and beyond
    • M ócsai, A. (2013) Diverse novel functions of neutrophils in immunity, inflammation, and beyond. J. Exp. Med. 210, 1283-1299
    • (2013) J. Exp. Med , vol.210 , pp. 1283-1299
    • M Ócsai, A.1
  • 4
    • 81255188938 scopus 로고    scopus 로고
    • The neutrophil in vascular inflammation
    • Phillipson, M., Kubes, P. (2011) The neutrophil in vascular inflammation. Nat. Med. 17, 1381-1390
    • (2011) Nat. Med , vol.17 , pp. 1381-1390
    • Phillipson, M.1    Kubes, P.2
  • 5
    • 84884889081 scopus 로고    scopus 로고
    • What’s your age again? Determination of human neutrophil half-lives revisited
    • Tak, T., Tesselaar, K., Pillay, J., Borghans, J. A., Koenderman, L. (2013) What’s your age again? Determination of human neutrophil half-lives revisited. J. Leukoc. Biol. 94, 595-601
    • (2013) J. Leukoc. Biol , vol.94 , pp. 595-601
    • Tak, T.1    Tesselaar, K.2    Pillay, J.3    Borghans, J.A.4    Koenderman, L.5
  • 6
    • 77955883153 scopus 로고    scopus 로고
    • Complement: A key system for immune surveillance and homeostasis
    • Ricklin, D., Hajishengallis, G., Yang, K., Lambris, J. D. (2010) Complement: a key system for immune surveillance and homeostasis. Nat. Immunol. 11, 785-797
    • (2010) Nat. Immunol , vol.11 , pp. 785-797
    • Ricklin, D.1    Hajishengallis, G.2    Yang, K.3    Lambris, J.D.4
  • 7
    • 79952123931 scopus 로고    scopus 로고
    • Microbial manipulation of receptor crosstalk in innate immunity
    • Hajishengallis, G., Lambris, J. D. (2011) Microbial manipulation of receptor crosstalk in innate immunity. Nat. Rev. Immunol. 11, 187-200
    • (2011) Nat. Rev. Immunol , vol.11 , pp. 187-200
    • Hajishengallis, G.1    Lambris, J.D.2
  • 9
    • 0023176046 scopus 로고
    • Human alveolar macrophages and monocytes generate the functional classical pathway of complement in vitro
    • Hetland, G., Johnson, E., Røyset, P., Eskeland, T. (1987) Human alveolar macrophages and monocytes generate the functional classical pathway of complement in vitro. Acta Pathol. Microbiol. Immunol. Scand. [C] 95, 117-122
    • (1987) Acta Pathol. Microbiol. Immunol. Scand. [C] , vol.95 , pp. 117-122
    • Hetland, G.1    Johnson, E.2    Røyset, P.3    Eskeland, T.4
  • 10
    • 84875442814 scopus 로고    scopus 로고
    • Neutrophil recruitment and function in health and inflammation
    • Kolaczkowska, E., Kubes, P. (2013) Neutrophil recruitment and function in health and inflammation. Nat. Rev. Immunol. 13, 159-175
    • (2013) Nat. Rev. Immunol , vol.13 , pp. 159-175
    • Kolaczkowska, E.1    Kubes, P.2
  • 12
    • 84864861276 scopus 로고    scopus 로고
    • The role of neutrophils during intestinal inflammation
    • Fournier, B. M., Parkos, C. A. (2012) The role of neutrophils during intestinal inflammation. Mucosal Immunol. 5, 354-366
    • (2012) Mucosal Immunol , vol.5 , pp. 354-366
    • Fournier, B.M.1    Parkos, C.A.2
  • 13
    • 84900395915 scopus 로고    scopus 로고
    • Expanding roles of neutrophils in aging hosts
    • Tseng, C. W., Liu, G. Y. (2014) Expanding roles of neutrophils in aging hosts. Curr. Opin. Immunol. 29, 43-48
    • (2014) Curr. Opin. Immunol , vol.29 , pp. 43-48
    • Tseng, C.W.1    Liu, G.Y.2
  • 14
    • 84891372427 scopus 로고    scopus 로고
    • Immunomicrobial pathogenesis of periodontitis: Keystones, pathobionts, and host response
    • Hajishengallis, G. (2014) Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response. Trends Immunol. 35, 3-11
    • (2014) Trends Immunol , vol.35 , pp. 3-11
    • Hajishengallis, G.1
  • 15
    • 78649375771 scopus 로고    scopus 로고
    • Neutrophils, from marrow to microbes
    • Borregaard, N. (2010) Neutrophils, from marrow to microbes. Immunity 33, 657-670
    • (2010) Immunity , vol.33 , pp. 657-670
    • Borregaard, N.1
  • 17
    • 77951597881 scopus 로고    scopus 로고
    • Breaching multiple barriers: Leukocyte motility through venular walls and the interstitium
    • Nourshargh, S., Hordijk, P. L., Sixt, M. (2010) Breaching multiple barriers: leukocyte motility through venular walls and the interstitium. Nat. Rev. Mol. Cell Biol. 11, 366-378
    • (2010) Nat. Rev. Mol. Cell Biol , vol.11 , pp. 366-378
    • Nourshargh, S.1    Hordijk, P.L.2    Sixt, M.3
  • 18
    • 34548230927 scopus 로고    scopus 로고
    • Getting to the site of inflammation: The leukocyte adhesion cascade updated
    • Ley, K., Laudanna, C., Cybulsky, M. I., Nourshargh, S. (2007) Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat. Rev. Immunol. 7, 678-689
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 678-689
    • Ley, K.1    Laudanna, C.2    Cybulsky, M.I.3    Nourshargh, S.4
  • 19
    • 70350450886 scopus 로고    scopus 로고
    • Novel aspects in the regulation of the leukocyte adhesion cascade
    • Chavakis, E., Choi, E. Y., Chavakis, T. (2009) Novel aspects in the regulation of the leukocyte adhesion cascade. Thromb. Haemost. 102, 191-197
    • (2009) Thromb. Haemost , vol.102 , pp. 191-197
    • Chavakis, E.1    Choi, E.Y.2    Chavakis, T.3
  • 20
    • 84871712393 scopus 로고    scopus 로고
    • Endogenous modulators of inflammatory cell recruitment
    • Hajishengallis, G., Chavakis, T. (2013) Endogenous modulators of inflammatory cell recruitment. Trends Immunol. 34, 1-6
    • (2013) Trends Immunol , vol.34 , pp. 1-6
    • Hajishengallis, G.1    Chavakis, T.2
  • 24
    • 84899714132 scopus 로고    scopus 로고
    • Developmental endothelial locus-1 attenuates complement-dependent phagocytosis through inhibition of Mac-1-integrin
    • Mitroulis, I., Kang, Y. Y., Gahmberg, C. G., Siegert, G., Hajishengallis, G., Chavakis, T., Choi, E. Y. (2014) Developmental endothelial locus-1 attenuates complement-dependent phagocytosis through inhibition of Mac-1-integrin. Thromb. Haemost. 111, 1004-1006
    • (2014) Thromb. Haemost , vol.111 , pp. 1004-1006
    • Mitroulis, I.1    Kang, Y.Y.2    Gahmberg, C.G.3    Siegert, G.4    Hajishengallis, G.5    Chavakis, T.6    Choi, E.Y.7
  • 26
    • 54049148978 scopus 로고    scopus 로고
    • Homeostatic regulation of blood neutrophil counts
    • Von Vietinghoff, S., Ley, K. (2008) Homeostatic regulation of blood neutrophil counts. J. Immunol. 181, 5183-5188
    • (2008) J. Immunol , vol.181 , pp. 5183-5188
    • Von Vietinghoff, S.1    Ley, K.2
  • 29
    • 15244344110 scopus 로고    scopus 로고
    • Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17
    • Stark, M. A., Huo, Y., Burcin, T. L., Morris, M. A., Olson, T. S., Ley, K. (2005) Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity 22, 285-294
    • (2005) Immunity , vol.22 , pp. 285-294
    • Stark, M.A.1    Huo, Y.2    Burcin, T.L.3    Morris, M.A.4    Olson, T.S.5    Ley, K.6
  • 30
    • 77954143695 scopus 로고    scopus 로고
    • Innate IL-17-producing cells: The sentinels of the immune system
    • Cua, D. J., Tato, C. M. (2010) Innate IL-17-producing cells: the sentinels of the immune system. Nat. Rev. Immunol. 10, 479-489
    • (2010) Nat. Rev. Immunol , vol.10 , pp. 479-489
    • Cua, D.J.1    Tato, C.M.2
  • 31
    • 84924611238 scopus 로고    scopus 로고
    • Neutrophil dysfunction and host susceptibility to periodontal inflammation: Current state of knowledge
    • Sima, C., Glogauer, M. (2014) Neutrophil dysfunction and host susceptibility to periodontal inflammation: current state of knowledge. Curr. Oral Health Rep. 1, 95-103
    • (2014) Curr. Oral Health Rep , vol.1 , pp. 95-103
    • Sima, C.1    Glogauer, M.2
  • 32
    • 84894443827 scopus 로고    scopus 로고
    • Neutrophil homeostasis and periodontal health in children and adults
    • Hajishengallis, E., Hajishengallis, G. (2014) Neutrophil homeostasis and periodontal health in children and adults. J. Dent. Res. 93, 231-237
    • (2014) J. Dent. Res , vol.93 , pp. 231-237
    • Hajishengallis, E.1    Hajishengallis, G.2
  • 33
    • 0037264098 scopus 로고    scopus 로고
    • Origin and function of the cellular components in gingival crevice fluid
    • Delima, A. J., Van Dyke, T. E. (2003) Origin and function of the cellular components in gingival crevice fluid. Periodontol. 2000 31, 55-76
    • (2003) Periodontol , vol.2000 , Issue.31 , pp. 55-76
    • Delima, A.J.1    Van Dyke, T.E.2
  • 34
    • 77953209789 scopus 로고    scopus 로고
    • Comparison of neutrophil functions in aggressive and chronic periodontitis
    • Ryder, M. I. (2010) Comparison of neutrophil functions in aggressive and chronic periodontitis. Periodontol. 2000 53, 124-137
    • (2010) Periodontol , vol.2000 , Issue.53 , pp. 124-137
    • Ryder, M.I.1
  • 35
    • 0038262824 scopus 로고    scopus 로고
    • Systemic disease and periodontitis: Manifestations of neutrophil dysfunction
    • Deas, D. E., Mackey, S. A., McDonnell, H. T. (2003) Systemic disease and periodontitis: manifestations of neutrophil dysfunction. Periodontol. 200032, 82-104
    • (2003) Periodontol , vol.2 , pp. 82-104
    • Deas, D.E.1    Mackey, S.A.2    McDonnell, H.T.3
  • 36
    • 44849143056 scopus 로고    scopus 로고
    • Why rare diseases are an important medical and social issue
    • Schieppati, A., Henter, J. I., Daina, E., Aperia, A. (2008) Why rare diseases are an important medical and social issue. Lancet 371, 2039-2041
    • (2008) Lancet , vol.371 , pp. 2039-2041
    • Schieppati, A.1    Henter, J.I.2    Daina, E.3    Aperia, A.4
  • 38
    • 33846100302 scopus 로고    scopus 로고
    • The role of reactive oxygen and antioxidant species in periodontal tissue destruction
    • Chapple, I. L., Matthews, J. B. (2007) The role of reactive oxygen and antioxidant species in periodontal tissue destruction. Periodontol. 2000 43, 160-232
    • (2007) Periodontol , vol.2000 , Issue.43 , pp. 160-232
    • Chapple, I.L.1    Matthews, J.B.2
  • 39
    • 79955586502 scopus 로고    scopus 로고
    • Refractory periodontitis population characterized by a hyperactive oral neutrophil phenotype
    • Aboodi, G. M., Goldberg, M. B., Glogauer, M. (2011) Refractory periodontitis population characterized by a hyperactive oral neutrophil phenotype. J. Periodontol. 82, 726-733
    • (2011) J. Periodontol , vol.82 , pp. 726-733
    • Aboodi, G.M.1    Goldberg, M.B.2    Glogauer, M.3
  • 40
    • 84880073932 scopus 로고    scopus 로고
    • Oral neutrophil transcriptome changes result in a pro-survival phenotype in periodontal diseases
    • Lakschevitz, F. S., Aboodi, G. M., Glogauer, M. (2013) Oral neutrophil transcriptome changes result in a pro-survival phenotype in periodontal diseases. PLoS ONE 8, e68983
    • (2013) Plos ONE , vol.8
    • Lakschevitz, F.S.1    Aboodi, G.M.2    Glogauer, M.3
  • 41
    • 0025169073 scopus 로고
    • Identification of polymorphonuclear leukocyte collagenase and gelatinase activities in mouthrinse samples: Correlation with periodontal disease activity in adult and juvenile periodontitis
    • Gangbar, S., Overall, C. M., McCulloch, C. A., Sodek, J. (1990) Identification of polymorphonuclear leukocyte collagenase and gelatinase activities in mouthrinse samples: correlation with periodontal disease activity in adult and juvenile periodontitis. J. Periodontal Res. 25, 257-267
    • (1990) J. Periodontal Res , vol.25 , pp. 257-267
    • Gangbar, S.1    Overall, C.M.2    McCulloch, C.A.3    Sodek, J.4
  • 42
    • 0029141399 scopus 로고
    • Evidence of a direct relationship between neutrophil collagenase activity and periodontal tissue destruction in vivo: Role of active enzyme in human periodontitis
    • Lee, W., Aitken, S., Sodek, J., McCulloch, C. A. (1995) Evidence of a direct relationship between neutrophil collagenase activity and periodontal tissue destruction in vivo: role of active enzyme in human periodontitis. J. Periodontal Res. 30, 23-33
    • (1995) J. Periodontal Res , vol.30 , pp. 23-33
    • Lee, W.1    Aitken, S.2    Sodek, J.3    McCulloch, C.A.4
  • 43
    • 78249233559 scopus 로고    scopus 로고
    • Associations between matrix metalloproteinase-8 and -14 and myeloperoxidase in gingival crevicular fluid from subjects with progressive chronic periodontitis: A longitudinal study
    • Hernández, M., Gamonal, J., Tervahartiala, T., Mäntylä, P., Rivera, O., Dezerega, A., Dutzan, N., Sorsa, T. (2010) Associations between matrix metalloproteinase-8 and -14 and myeloperoxidase in gingival crevicular fluid from subjects with progressive chronic periodontitis: a longitudinal study. J. Periodontol. 81, 1644-1652
    • (2010) J. Periodontol , vol.81 , pp. 1644-1652
    • Hernández, M.1    Gamonal, J.2    Tervahartiala, T.3    Mäntylä, P.4    Rivera, O.5    Dezerega, A.6    Dutzan, N.7    Sorsa, T.8
  • 45
    • 84928290441 scopus 로고    scopus 로고
    • Quantifying oral inflammatory load: Oral neutrophil counts in periodontal health and disease
    • [Epub ahead of print]
    • Landzberg, M., Doering, H., Aboodi, G. M., Tenenbaum, H. C., Glogauer, M. (2014) Quantifying oral inflammatory load: oral neutrophil counts in periodontal health and disease. J. Periodont. Res. doi: 10.1111/jre.12211 [Epub ahead of print]
    • (2014) J. Periodont. Res
    • Landzberg, M.1    Doering, H.2    Aboodi, G.M.3    Tenenbaum, H.C.4    Glogauer, M.5
  • 46
    • 84902990206 scopus 로고    scopus 로고
    • Regulation of immune responses by neutrophils
    • Wang, J., Arase, H. (2014) Regulation of immune responses by neutrophils. Ann. N. Y. Acad. Sci. 1319, 66-81
    • (2014) Ann. N. Y. Acad. Sci , vol.1319 , pp. 66-81
    • Wang, J.1    Arase, H.2
  • 48
    • 84896042568 scopus 로고    scopus 로고
    • When neutrophils meet T cells: Beginnings of a tumultuous relationship with underappreciated potential
    • Kalyan, S., Kabelitz, D. (2014) When neutrophils meet T cells: beginnings of a tumultuous relationship with underappreciated potential. Eur. J. Immunol. 44, 627-633
    • (2014) Eur. J. Immunol , vol.44 , pp. 627-633
    • Kalyan, S.1    Kabelitz, D.2
  • 49
    • 84866934694 scopus 로고    scopus 로고
    • Targeting IL-17 and TH17 cells in chronic inflammation
    • Miossec, P., Kolls, J. K. (2012) Targeting IL-17 and TH17 cells in chronic inflammation. Nat. Rev. Drug Discov. 11, 763-776
    • (2012) Nat. Rev. Drug Discov , vol.11 , pp. 763-776
    • Miossec, P.1    Kolls, J.K.2
  • 50
    • 84873691650 scopus 로고    scopus 로고
    • The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin
    • Weaver, C. T., Elson, C. O., Fouser, L. A., Kolls, J. K. (2013) The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin. Annu. Rev. Pathol. 8, 477-512
    • (2013) Annu. Rev. Pathol , vol.8 , pp. 477-512
    • Weaver, C.T.1    Elson, C.O.2    Fouser, L.A.3    Kolls, J.K.4
  • 51
    • 84900863061 scopus 로고    scopus 로고
    • The presence, function and regulation of IL-17 and Th17 cells in periodontitis
    • Cheng, W. C., Hughes, F. J., Taams, L. S. (2014) The presence, function and regulation of IL-17 and Th17 cells in periodontitis. J. Clin. Periodontol. 41, 541-549
    • (2014) J. Clin. Periodontol , vol.41 , pp. 541-549
    • Cheng, W.C.1    Hughes, F.J.2    Taams, L.S.3
  • 53
    • 84875629527 scopus 로고    scopus 로고
    • The molecular basis of leukocyte recruitment and its deficiencies. Mol
    • Schmidt, S., Moser, M., Sperandio, M. (2013) The molecular basis of leukocyte recruitment and its deficiencies. Mol. Immunol. 55, 49-58
    • (2013) Immunol , vol.55 , pp. 49-58
    • Schmidt, S.1    Moser, M.2    Sperandio, M.3
  • 54
    • 84857478993 scopus 로고    scopus 로고
    • Leukocyte adhesion deficiencies
    • Hanna, S., Etzioni, A. (2012) Leukocyte adhesion deficiencies. Ann. N. Y. Acad. Sci. 1250, 50-55
    • (2012) Ann. N. Y. Acad. Sci , vol.1250 , pp. 50-55
    • Hanna, S.1    Etzioni, A.2
  • 55
    • 0023358620 scopus 로고
    • Periodontal manifestations of the heritable Mac-1, LFA-1, deficiency syndrome. Clinical, histopathologic and molecular characteristics
    • Waldrop, T. C., Anderson, D. C., Hallmon, W. W., Schmalstieg, F. C., Jacobs, R. L. (1987) Periodontal manifestations of the heritable Mac-1, LFA-1, deficiency syndrome. Clinical, histopathologic and molecular characteristics. J. Periodontol. 58, 400-416
    • (1987) J. Periodontol , vol.58 , pp. 400-416
    • Waldrop, T.C.1    Erson, D.C.2    Hallmon, W.W.3    Schmalstieg, F.C.4    Jacobs, R.L.5
  • 56
    • 0642336935 scopus 로고    scopus 로고
    • Genes and gene polymorphisms associated with periodontal disease
    • Kinane, D. F., Hart, T. C. (2003) Genes and gene polymorphisms associated with periodontal disease. Crit. Rev. Oral Biol. Med. 14, 430-449
    • (2003) Crit. Rev. Oral Biol. Med , vol.14 , pp. 430-449
    • Kinane, D.F.1    Hart, T.C.2
  • 58
    • 79951889113 scopus 로고    scopus 로고
    • How has neutrophil research improved our understanding of periodontal pathogenesis
    • Nussbaum, G., Shapira, L. (2011) How has neutrophil research improved our understanding of periodontal pathogenesis? J. Clin. Periodontol. 38 (Suppl 11), 49-59
    • (2011) J. Clin. Periodontol , vol.38 , pp. 49-59
    • Nussbaum, G.1    Shapira, L.2
  • 59
    • 0034515822 scopus 로고    scopus 로고
    • Leukocyte adhesion deficiency II-from A to almost Z
    • Etzioni, A., Tonetti, M. (2000) Leukocyte adhesion deficiency II-from A to almost Z. Immunol. Rev. 178, 138-147
    • (2000) Immunol. Rev , vol.178 , pp. 138-147
    • Etzioni, A.1    Tonetti, M.2
  • 60
    • 17144393271 scopus 로고    scopus 로고
    • Systemic conditions associated with periodontitis in childhood and adolescence. A review of diagnostic possibilities
    • Sollecito, T. P., Sullivan, K. E., Pinto, A., Stewart, J., Korostoff, J. (2005) Systemic conditions associated with periodontitis in childhood and adolescence. A review of diagnostic possibilities. Med. Oral Patol. Oral Cir. Bucal 10, 142-150
    • (2005) Med. Oral Patol. Oral Cir. Bucal , vol.10 , pp. 142-150
    • Sollecito, T.P.1    Sullivan, K.E.2    Pinto, A.3    Stewart, J.4    Korostoff, J.5
  • 62
    • 70349968220 scopus 로고    scopus 로고
    • IL-17 as a future therapeutic target for rheumatoid arthritis
    • Van den Berg, W. B., Miossec, P. (2009) IL-17 as a future therapeutic target for rheumatoid arthritis. Nat. Rev. Rheumatol. 5, 549-553
    • (2009) Nat. Rev. Rheumatol , vol.5 , pp. 549-553
    • Van Den Berg, W.B.1    Miossec, P.2
  • 63
    • 68649088121 scopus 로고    scopus 로고
    • Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity
    • Sutton, C. E., Lalor, S. J., Sweeney, C. M., Brereton, C. F., Lavelle, E. C., Mills, K. H. (2009) Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. Immunity 31, 331-341
    • (2009) Immunity , vol.31 , pp. 331-341
    • Sutton, C.E.1    Lalor, S.J.2    Sweeney, C.M.3    Brereton, C.F.4    Lavelle, E.C.5    Mills, K.H.6
  • 64
    • 84911397225 scopus 로고    scopus 로고
    • The inflammophilic character of the periodontitis-associated microbiota
    • Hajishengallis, G. (2014) The inflammophilic character of the periodontitis-associated microbiota. Mol. Oral Microbiol. 29, 48-57
    • (2014) Mol. Oral Microbiol , vol.29 , pp. 48-57
    • Hajishengallis, G.1
  • 67
    • 16644396846 scopus 로고    scopus 로고
    • The junctional epithelium: From health to disease
    • Bosshardt, D. D., Lang, N. P. (2005) The junctional epithelium: from health to disease. J. Dent. Res. 84, 9-20
    • (2005) J. Dent. Res , vol.84 , pp. 9-20
    • Bosshardt, D.D.1    Lang, N.P.2
  • 70
    • 78650674708 scopus 로고    scopus 로고
    • Rac GTPases in human diseases
    • Pai, S. Y., Kim, C., Williams, D. A. (2010) Rac GTPases in human diseases. Dis. Markers 29, 177-187
    • (2010) Dis. Markers , vol.29 , pp. 177-187
    • Pai, S.Y.1    Kim, C.2    Williams, D.A.3
  • 71
    • 84892150941 scopus 로고    scopus 로고
    • Rac-null leukocytes are associated with increased inflammation-mediated alveolar bone loss
    • Sima, C., Gastfreund, S., Sun, C., Glogauer, M. (2014) Rac-null leukocytes are associated with increased inflammation-mediated alveolar bone loss. Am. J. Pathol. 184, 472-482
    • (2014) Am. J. Pathol , vol.184 , pp. 472-482
    • Sima, C.1    Gastfreund, S.2    Sun, C.3    Glogauer, M.4
  • 72
    • 84904279627 scopus 로고    scopus 로고
    • Etiology of leukocyte adhesion deficiency-associated periodontitis revisited: Not a raging infection but a raging inflammatory response
    • Hajishengallis, G., Moutsopoulos, N. M. (2014) Etiology of leukocyte adhesion deficiency-associated periodontitis revisited: not a raging infection but a raging inflammatory response. Expert Rev. Clin. Immunol. 10, 973-975
    • (2014) Expert Rev. Clin. Immunol , vol.10 , pp. 973-975
    • Hajishengallis, G.1    Moutsopoulos, N.M.2
  • 73
    • 84892827750 scopus 로고    scopus 로고
    • Activation of neutrophils by autocrine IL- 17A-IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORgt and dectin-2
    • Taylor, P. R., Roy, S., Leal, S. M. Jr., Sun, Y., Howell, S. J., Cobb, B. A., Li, X., Pearlman, E. (2014) Activation of neutrophils by autocrine IL- 17A-IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORgt and dectin-2. Nat. Immunol. 15, 143-151
    • (2014) Nat. Immunol , vol.15 , pp. 143-151
    • Taylor, P.R.1    Roy, S.2    Leal, S.M.3    Sun, Y.4    Howell, S.J.5    Cobb, B.A.6    Li, X.7    Pearlman, E.8
  • 75
    • 84893742603 scopus 로고    scopus 로고
    • Expression and function of the homeostatic molecule Del-1 in endothelial cells and the periodontal tissue
    • 617809
    • Shin, J., Hosur, K. B., Pyaram, K., Jotwani, R., Liang, S., Chavakis, T., Hajishengallis, G. (2013) Expression and function of the homeostatic molecule Del-1 in endothelial cells and the periodontal tissue. Clin. Dev. Immunol. 2013, 617809
    • (2013) Clin. Dev. Immunol , vol.2013
    • Shin, J.1    Hosur, K.B.2    Pyaram, K.3    Jotwani, R.4    Liang, S.5    Chavakis, T.6    Hajishengallis, G.7
  • 77
    • 70350510860 scopus 로고    scopus 로고
    • IL-17 induces osteoclastogenesis from human monocytes alone in the absence of osteoblasts, which is potently inhibited by anti-TNF-alpha antibody: A novel mechanism of osteoclastogenesis by IL-17
    • Yago, T., Nanke, Y., Ichikawa, N., Kobashigawa, T., Mogi, M., Kamatani, N., Kotake, S. (2009) IL-17 induces osteoclastogenesis from human monocytes alone in the absence of osteoblasts, which is potently inhibited by anti-TNF-alpha antibody: a novel mechanism of osteoclastogenesis by IL-17. J. Cell. Biochem. 108, 947-955
    • (2009) J. Cell. Biochem , vol.108 , pp. 947-955
    • Yago, T.1    Nanke, Y.2    Ichikawa, N.3    Kobashigawa, T.4    Mogi, M.5    Kamatani, N.6    Kotake, S.7
  • 79
    • 70349565586 scopus 로고    scopus 로고
    • Surface RANKL of Toll-like receptor 4-stimulated human neutrophils activates osteoclastic bone resorption
    • Chakravarti, A., Raquil, M. A., Tessier, P., Poubelle, P. E. (2009) Surface RANKL of Toll-like receptor 4-stimulated human neutrophils activates osteoclastic bone resorption. Blood 114, 1633-1644
    • (2009) Blood , vol.114 , pp. 1633-1644
    • Chakravarti, A.1    Raquil, M.A.2    Tessier, P.3    Poubelle, P.E.4
  • 81
    • 84893587232 scopus 로고    scopus 로고
    • Breaking bad: Manipulation of the host response by Porphyromonas gingivalis
    • Hajishengallis, G., Lamont, R. J. (2014) Breaking bad: manipulation of the host response by Porphyromonas gingivalis. Eur. J. Immunol. 44, 328-338
    • (2014) Eur. J. Immunol , vol.44 , pp. 328-338
    • Hajishengallis, G.1    Lamont, R.J.2
  • 83
    • 33845462504 scopus 로고    scopus 로고
    • Cutting edge: TLR2 is required for the innate response to Porphyromonas gingivalis: Activation leads to bacterial persistence and TLR2 deficiency attenuates induced alveolar bone resorption
    • Burns, E., Bachrach, G., Shapira, L., Nussbaum, G. (2006) Cutting edge: TLR2 is required for the innate response to Porphyromonas gingivalis: activation leads to bacterial persistence and TLR2 deficiency attenuates induced alveolar bone resorption. J. Immunol. 177, 8296-8300
    • (2006) J. Immunol , vol.177 , pp. 8296-8300
    • Burns, E.1    Bachrach, G.2    Shapira, L.3    Nussbaum, G.4
  • 84
    • 79251544574 scopus 로고    scopus 로고
    • The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss
    • Liang, S., Krauss, J. L., Domon, H., McIntosh, M. L., Hosur, K. B., Qu, H., Li, F., Tzekou, A., Lambris, J. D., Hajishengallis, G. (2011) The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss. J. Immunol. 186, 869-877
    • (2011) J. Immunol , vol.186 , pp. 869-877
    • Liang, S.1    Krauss, J.L.2    Domon, H.3    McIntosh, M.L.4    Hosur, K.B.5    Qu, H.6    Li, F.7    Tzekou, A.8    Lambris, J.D.9    Hajishengallis, G.10
  • 85
    • 34249799593 scopus 로고    scopus 로고
    • Biphasic effect of gingipains from Porphyromonas gingivalis on the human complement system
    • Popadiak, K., Potempa, J., Riesbeck, K., Blom, A. M. (2007) Biphasic effect of gingipains from Porphyromonas gingivalis on the human complement system. J. Immunol. 178, 7242-7250
    • (2007) J. Immunol , vol.178 , pp. 7242-7250
    • Popadiak, K.1    Potempa, J.2    Riesbeck, K.3    Blom, A.M.4
  • 86
    • 77949316163 scopus 로고    scopus 로고
    • TLR2-dependent inflammatory response to Porphyromonas gingivalis is MyD88 independent, whereas MyD88 is required to clear infection
    • Burns, E., Eliyahu, T., Uematsu, S., Akira, S., Nussbaum, G. (2010) TLR2-dependent inflammatory response to Porphyromonas gingivalis is MyD88 independent, whereas MyD88 is required to clear infection. J. Immunol. 184, 1455-1462
    • (2010) J. Immunol , vol.184 , pp. 1455-1462
    • Burns, E.1    Eliyahu, T.2    Uematsu, S.3    Akira, S.4    Nussbaum, G.5
  • 88
    • 84876842615 scopus 로고    scopus 로고
    • The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation
    • Abusleme, L., Dupuy, A. K., Dutzan, N., Silva, N., Burleson, J. A., Strausbaugh, L. D., Gamonal, J., Diaz, P. I. (2013) The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation. ISME J. 7, 1016-1025
    • (2013) ISME J , vol.7 , pp. 1016-1025
    • Abusleme, L.1    Dupuy, A.K.2    Dutzan, N.3    Silva, N.4    Burleson, J.A.5    Strausbaugh, L.D.6    Gamonal, J.7    Diaz, P.I.8
  • 89
    • 84865276077 scopus 로고    scopus 로고
    • Porphyromonas gingivalis as a potential community activist for disease
    • Darveau, R. P., Hajishengallis, G., Curtis, M. A. (2012) Porphyromonas gingivalis as a potential community activist for disease. J. Dent. Res. 91, 816-820
    • (2012) J. Dent. Res , vol.91 , pp. 816-820
    • Darveau, R.P.1    Hajishengallis, G.2    Curtis, M.A.3
  • 90
    • 82955237696 scopus 로고    scopus 로고
    • Genetic susceptibility to periodontitis
    • Laine, M. L., Crielaard, W., Loos, B. G. (2012) Genetic susceptibility to periodontitis. Periodontol. 2000 58, 37-68
    • (2012) Periodontol , vol.2000 , Issue.58 , pp. 37-68
    • Laine, M.L.1    Crielaard, W.2    Loos, B.G.3
  • 91
    • 0028457299 scopus 로고
    • Evidence of bacterial etiology: A historical perspective
    • Socransky, S. S., Haffajee, A. D. (1994) Evidence of bacterial etiology: a historical perspective. Periodontol. 2000 5, 7-25
    • (1994) Periodontol , vol.2000 , Issue.5 , pp. 7-25
    • Socransky, S.S.1    Haffajee, A.D.2
  • 92
    • 84952658997 scopus 로고    scopus 로고
    • Diabetes and periodontal diseases: Consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases
    • Chapple, I. L., Genco, R.; Working Group 2 of the Joint EFP/AAP Workshop. (2013) Diabetes and periodontal diseases: consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases. J. Periodontol. 84, (4 Suppl), S106-S112
    • (2013) J. Periodontol , vol.84 , pp. S106-S112
    • Chapple, I.L.1    Genco, R.2
  • 93
    • 82155185364 scopus 로고    scopus 로고
    • Diabetes mellitus and periodontitis: A tale of two common interrelated diseases
    • Lalla, E., Papapanou, P. N. (2011) Diabetes mellitus and periodontitis: a tale of two common interrelated diseases. Nat. Rev. Endocrinol. 7, 738-748
    • (2011) Nat. Rev. Endocrinol , vol.7 , pp. 738-748
    • Lalla, E.1    Papapanou, P.N.2
  • 95
    • 3042598376 scopus 로고    scopus 로고
    • Diabetes prolongs the inflammatory response to a bacterial stimulus through cytokine dysregulation
    • Naguib, G., Al-Mashat, H., Desta, T., Graves, D. T. (2004) Diabetes prolongs the inflammatory response to a bacterial stimulus through cytokine dysregulation. J. Invest. Dermatol. 123, 87-92
    • (2004) J. Invest. Dermatol , vol.123 , pp. 87-92
    • Naguib, G.1    Al-Mashat, H.2    Desta, T.3    Graves, D.T.4
  • 96
    • 33644976835 scopus 로고    scopus 로고
    • Diabetes-enhanced inflammation and apoptosis-impact on periodontal pathology
    • Graves, D. T., Liu, R., Alikhani, M., Al-Mashat, H., Trackman, P. C. (2006) Diabetes-enhanced inflammation and apoptosis-impact on periodontal pathology. J. Dent. Res. 85, 15-21
    • (2006) J. Dent. Res , vol.85 , pp. 15-21
    • Graves, D.T.1    Liu, R.2    Alikhani, M.3    Al-Mashat, H.4    Trackman, P.C.5
  • 97
    • 56149111933 scopus 로고    scopus 로고
    • Resistin inhibits essential functions of polymorphonuclear leukocytes
    • Cohen, G., Ilic, D., Raupachova, J., H örl, W. H. (2008) Resistin inhibits essential functions of polymorphonuclear leukocytes. J. Immunol. 181, 3761-3768
    • (2008) J. Immunol , vol.181 , pp. 3761-3768
    • Cohen, G.1    Ilic, D.2    Raupachova, J.3    H Örl, W.H.4
  • 98
    • 77958531151 scopus 로고    scopus 로고
    • Type 1 diabetes predisposes to enhanced gingival leukocyte margination and macromolecule extravasation in vivo
    • Sima, C., Rhourida, K., Van Dyke, T. E., Gyurko, R. (2010) Type 1 diabetes predisposes to enhanced gingival leukocyte margination and macromolecule extravasation in vivo. J. Periodontal Res. 45, 748-756
    • (2010) J. Periodontal Res , vol.45 , pp. 748-756
    • Sima, C.1    Rhourida, K.2    Van Dyke, T.E.3    Gyurko, R.4
  • 102
    • 52649128246 scopus 로고    scopus 로고
    • A new inflammatory cytokine on the block: Re-thinking periodontal disease and the Th1/Th2 paradigm in the context of Th17 cells and IL-17
    • Gaffen, S. L., Hajishengallis, G. (2008) A new inflammatory cytokine on the block: re-thinking periodontal disease and the Th1/Th2 paradigm in the context of Th17 cells and IL-17. J. Dent. Res. 87, 817-828
    • (2008) J. Dent. Res , vol.87 , pp. 817-828
    • Gaffen, S.L.1    Hajishengallis, G.2
  • 104
    • 84869761067 scopus 로고    scopus 로고
    • Local complement-targeted intervention in periodontitis: Proof-of-concept using a C5a receptor (CD88) antagonist
    • Abe, T., Hosur, K. B., Hajishengallis, E., Reis, E. S., Ricklin, D., Lambris, J. D., Hajishengallis, G. (2012) Local complement-targeted intervention in periodontitis: proof-of-concept using a C5a receptor (CD88) antagonist. J. Immunol. 189, 5442-5448
    • (2012) J. Immunol , vol.189 , pp. 5442-5448
    • Abe, T.1    Hosur, K.B.2    Hajishengallis, E.3    Reis, E.S.4    Ricklin, D.5    Lambris, J.D.6    Hajishengallis, G.7
  • 105
    • 84867736584 scopus 로고    scopus 로고
    • Therapeutic potential of targeting IL-17
    • Jones, S. A., Sutton, C. E., Cua, D., Mills, K. H. (2012) Therapeutic potential of targeting IL-17. Nat. Immunol. 13, 1022-1025
    • (2012) Nat. Immunol , vol.13 , pp. 1022-1025
    • Jones, S.A.1    Sutton, C.E.2    Cua, D.3    Mills, K.H.4
  • 106
    • 84875990477 scopus 로고    scopus 로고
    • Complement in immune and inflammatory disorders: Therapeutic interventions
    • Ricklin, D., Lambris, J. D. (2013) Complement in immune and inflammatory disorders: therapeutic interventions. J. Immunol. 190, 3839-3847.
    • (2013) J. Immunol , vol.190 , pp. 3839-3847
    • Ricklin, D.1    Lambris, J.D.2


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