-
1
-
-
84866507629
-
Prevalence of periodontitis in adults in the United States: 2009 and 2010
-
Eke, P. I., B. A. Dye, L. Wei, G. O. Thornton-Evans, and R. J. Genco. 2012. Prevalence of periodontitis in adults in the United States: 2009 and 2010. J. Dent. Res. 91:914-920.
-
(2012)
J. Dent. Res.
, vol.91
, pp. 914-920
-
-
Eke, P.I.1
Dye, B.A.2
Wei, L.3
Thornton-Evans, G.O.4
Genco, R.J.5
-
3
-
-
84891372427
-
Immunomicrobial pathogenesis of periodontitis: Keystones, pathobionts, and host response
-
Hajishengallis, G. 2014. Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response. Trends Immunol. 35:3-11.
-
(2014)
Trends Immunol.
, vol.35
, pp. 3-11
-
-
Hajishengallis, G.1
-
4
-
-
33847346939
-
Treatment of periodontitis and endothelial function
-
Tonetti, M. S., F. D'Aiuto, L. Nibali, A. Donald, C. Storry, M. Parkar, J. Suvan, A. D. Hingorani, P. Vallance, and J. Deanfield. 2007. Treatment of periodontitis and endothelial function. N. Engl. J. Med. 356:911-920.
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 911-920
-
-
Tonetti, M.S.1
D'Aiuto, F.2
Nibali, L.3
Donald, A.4
Storry, C.5
Parkar, M.6
Suvan, J.7
Hingorani, A.D.8
Vallance, P.9
Deanfield, J.10
-
5
-
-
78649810453
-
Periodontitis in RA - The citrullinated enolase connection
-
Lundberg, K., N. Wegner, T. Yucel-Lindberg, and P. J. Venables. 2010. Periodontitis in RA - the citrullinated enolase connection. Nat. Rev. Rheumatol. 6:727-730.
-
(2010)
Nat. Rev. Rheumatol.
, vol.6
, pp. 727-730
-
-
Lundberg, K.1
Wegner, N.2
Yucel-Lindberg, T.3
Venables, P.J.4
-
6
-
-
82155185364
-
Diabetes mellitus and periodontitis: A tale of two common interrelated diseases
-
Lalla, E., and P. N. Papapanou. 2011. Diabetes mellitus and periodontitis: a tale of two common interrelated diseases. Nat. Rev. Endocrinol. 7:738-748.
-
(2011)
Nat. Rev. Endocrinol.
, vol.7
, pp. 738-748
-
-
Lalla, E.1
Papapanou, P.N.2
-
7
-
-
84893200159
-
Adverse pregnancy outcomes (APOs) and periodontal disease: Pathogenic mechanisms
-
Madianos, P. N., Y. A. Bobetsis, and S. Offenbacher. 2013. Adverse pregnancy outcomes (APOs) and periodontal disease: pathogenic mechanisms. J. Clin. Periodontol. 40(Suppl 14):S170-S180.
-
(2013)
J. Clin. Periodontol.
, vol.40
, Issue.SUPPL. 14
-
-
Madianos, P.N.1
Bobetsis, Y.A.2
Offenbacher, S.3
-
9
-
-
78650062475
-
Oral biofilm-associated diseases: Trends and implications for quality of life, systemic health and expenditures
-
Beikler, T., and T. F. Flemmig. 2011. Oral biofilm-associated diseases: trends and implications for quality of life, systemic health and expenditures. Periodontol. 2000 55:87-103.
-
(2011)
Periodontol. 2000
, vol.55
, pp. 87-103
-
-
Beikler, T.1
Flemmig, T.F.2
-
10
-
-
0036370385
-
Classifying periodontal diseases-a long-standing dilemma
-
Armitage, G. C. 2002. Classifying periodontal diseases-a long-standing dilemma. Periodontol. 2000 30:9-23.
-
(2002)
Periodontol. 2000
, vol.30
, pp. 9-23
-
-
Armitage, G.C.1
-
11
-
-
69949120119
-
Comparisons of subgingival microbial profiles of refractory periodontitis, severe periodontitis, and periodontal health using the human oral microbe identification microarray
-
Colombo, A. P., S. K. Boches, S. L. Cotton, J. M. Goodson, R. Kent, A. D. Haffajee, S. S. Socransky, H. Hasturk, T. E. Van Dyke, F. Dewhirst, and B. J. Paster. 2009. Comparisons of subgingival microbial profiles of refractory periodontitis, severe periodontitis, and periodontal health using the human oral microbe identification microarray. J. Periodontol. 80:1421-1432.
-
(2009)
J. Periodontol.
, vol.80
, pp. 1421-1432
-
-
Colombo, A.P.1
Boches, S.K.2
Cotton, S.L.3
Goodson, J.M.4
Kent, R.5
Haffajee, A.D.6
Socransky, S.S.7
Hasturk, H.8
Van Dyke, T.E.9
Dewhirst, F.10
Paster, B.J.11
-
12
-
-
84855560497
-
Paradigm shift in the pharmacological management of periodontal diseases
-
Hasturk, H., A. Kantarci, and T. E. Van Dyke. 2012. Paradigm shift in the pharmacological management of periodontal diseases. Front. Oral Biol. 15:160-176.
-
(2012)
Front. Oral Biol.
, vol.15
, pp. 160-176
-
-
Hasturk, H.1
Kantarci, A.2
Van Dyke, T.E.3
-
13
-
-
84934434579
-
Complement-targeted therapeutics in periodontitis
-
Hajishengallis, G., and J. D. Lambris. 2013. Complement-targeted therapeutics in periodontitis. Adv. Exp. Med. Biol. 735:197-206.
-
(2013)
Adv. Exp. Med. Biol.
, vol.735
, pp. 197-206
-
-
Hajishengallis, G.1
Lambris, J.D.2
-
14
-
-
78049417345
-
Complement and periodontitis
-
Hajishengallis, G. 2010. Complement and periodontitis. Biochem. Pharmacol. 80:1992-2001.
-
(2010)
Biochem. Pharmacol.
, vol.80
, pp. 1992-2001
-
-
Hajishengallis, G.1
-
16
-
-
77955883153
-
Complement: A key system for immune surveillance and homeostasis
-
Ricklin, D., G. Hajishengallis, K. Yang, and J. D. Lambris. 2010. Complement: a key system for immune surveillance and homeostasis. Nat. Immunol. 11:785-797.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 785-797
-
-
Ricklin, D.1
Hajishengallis, G.2
Yang, K.3
Lambris, J.D.4
-
17
-
-
0024528560
-
Assessment of complement cleavage in gingival fluid during experimental gingivitis in man
-
Patters, M. R., C. E. Niekrash, and N. P. Lang. 1989. Assessment of complement cleavage in gingival fluid during experimental gingivitis in man. J. Clin. Periodontol. 16:33-37.
-
(1989)
J. Clin. Periodontol.
, vol.16
, pp. 33-37
-
-
Patters, M.R.1
Niekrash, C.E.2
Lang, N.P.3
-
18
-
-
0023355237
-
Deposits of immunoglobulins, complement, and immune complexes in inflamed human gingiva
-
Nikolopoulou-Papaconstantinou, A. A., A. C. Johannessen, and T. Kristoffersen. 1987. Deposits of immunoglobulins, complement, and immune complexes in inflamed human gingiva. Acta Odontol. Scand. 45:187-193.
-
(1987)
Acta Odontol. Scand.
, vol.45
, pp. 187-193
-
-
Nikolopoulou-Papaconstantinou, A.A.1
Johannessen, A.C.2
Kristoffersen, T.3
-
19
-
-
0017398665
-
Detection of functional complement components in gingival crevicular fluid from humans with periodontal diseases
-
Courts, F. J., R. J. Boackle, H. H. Fudenberg, and M. S. Silverman. 1977. Detection of functional complement components in gingival crevicular fluid from humans with periodontal diseases. J. Dent. Res. 56:327-331.
-
(1977)
J. Dent. Res.
, vol.56
, pp. 327-331
-
-
Courts, F.J.1
Boackle, R.J.2
Fudenberg, H.H.3
Silverman, M.S.4
-
20
-
-
0017605530
-
Gingival fluid and serum in periodontal diseases. II. Evidence for cleavage of complement components C3, C3 proactivator (factor B) and C4 in gingival fluid
-
Schenkein, H. A., and R. J. Genco. 1977. Gingival fluid and serum in periodontal diseases. II. Evidence for cleavage of complement components C3, C3 proactivator (factor B) and C4 in gingival fluid. J. Periodontol. 48:778-784.
-
(1977)
J. Periodontol.
, vol.48
, pp. 778-784
-
-
Schenkein, H.A.1
Genco, R.J.2
-
21
-
-
0022710062
-
Assessment of complement cleavage in gingival fluid in humans with and without periodontal disease
-
Niekrash, C. E., and M. R. Patters. 1986. Assessment of complement cleavage in gingival fluid in humans with and without periodontal disease. J. Periodontal Res. 21:233-242.
-
(1986)
J. Periodontal Res.
, vol.21
, pp. 233-242
-
-
Niekrash, C.E.1
Patters, M.R.2
-
22
-
-
81755166205
-
Lowabundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement
-
Hajishengallis, G., S. Liang, M. A. Payne, A. Hashim, R. Jotwani, M. A. Eskan, M. L. McIntosh, A. Alsam, K. L. Kirkwood, J. D. Lambris, et al. 2011. Lowabundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement. Cell Host Microbe 10:497-506.
-
(2011)
Cell Host Microbe
, vol.10
, pp. 497-506
-
-
Hajishengallis, G.1
Liang, S.2
Payne, M.A.3
Hashim, A.4
Jotwani, R.5
Eskan, M.A.6
McIntosh, M.L.7
Alsam, A.8
Kirkwood, K.L.9
Lambris, J.D.10
-
24
-
-
84869761067
-
Local complement-targeted intervention in periodontitis: Proof-of-concept using a C5a receptor (CD88) antagonist
-
Abe, T., K. B. Hosur, E. Hajishengallis, E. S. Reis, D. Ricklin, J. D. Lambris, and G. Hajishengallis. 2012. Local complement-targeted intervention in periodontitis: proof-of-concept using a C5a receptor (CD88) antagonist. J. Immunol. 189:5442-5448.
-
(2012)
J. Immunol.
, vol.189
, pp. 5442-5448
-
-
Abe, T.1
Hosur, K.B.2
Hajishengallis, E.3
Reis, E.S.4
Ricklin, D.5
Lambris, J.D.6
Hajishengallis, G.7
-
25
-
-
84879887362
-
Role of complement in host-microbe homeostasis of the periodontium
-
Hajishengallis, G., T. Abe, T. Maekawa, E. Hajishengallis, and J. D. Lambris. 2013. Role of complement in host-microbe homeostasis of the periodontium. Semin. Immunol. 25:65-72.
-
(2013)
Semin. Immunol.
, vol.25
, pp. 65-72
-
-
Hajishengallis, G.1
Abe, T.2
Maekawa, T.3
Hajishengallis, E.4
Lambris, J.D.5
-
27
-
-
77950187399
-
Microbial hijacking of complement-toll-like receptor crosstalk
-
Wang, M., J. L. Krauss, H. Domon, K. B. Hosur, S. Liang, P. Magotti, M. Triantafilou, K. Triantafilou, J. D. Lambris, and G. Hajishengallis. 2010. Microbial hijacking of complement-toll-like receptor crosstalk. Sci. Signal. 3: ra11.
-
(2010)
Sci. Signal.
, vol.3
-
-
Wang, M.1
Krauss, J.L.2
Domon, H.3
Hosur, K.B.4
Liang, S.5
Magotti, P.6
Triantafilou, M.7
Triantafilou, K.8
Lambris, J.D.9
Hajishengallis, G.10
-
28
-
-
77957357555
-
The human oral microbiome
-
Dewhirst, F. E., T. Chen, J. Izard, B. J. Paster, A. C. Tanner, W. H. Yu, A. Lakshmanan, and W. G. Wade. 2010. The human oral microbiome. J. Bacteriol. 192:5002-5017.
-
(2010)
J. Bacteriol.
, vol.192
, pp. 5002-5017
-
-
Dewhirst, F.E.1
Chen, T.2
Izard, J.3
Paster, B.J.4
Tanner, A.C.5
Yu, W.H.6
Lakshmanan, A.7
Wade, W.G.8
-
29
-
-
84861342868
-
Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing
-
Griffen, A. L., C. J. Beall, J. H. Campbell, N. D. Firestone, P. S. Kumar, Z. K. Yang, M. Podar, and E. J. Leys. 2012. Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing. ISME J. 6:1176-1185.
-
(2012)
ISME J.
, vol.6
, pp. 1176-1185
-
-
Griffen, A.L.1
Beall, C.J.2
Campbell, J.H.3
Firestone, N.D.4
Kumar, P.S.5
Yang, Z.K.6
Podar, M.7
Leys, E.J.8
-
30
-
-
84876842615
-
The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation
-
Abusleme, L., A. K. Dupuy, N. Dutzan, N. Silva, J. A. Burleson, L. D. Strausbaugh, J. Gamonal, and P. I. Diaz. 2013. The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation. ISME J. 7:1016-1025.
-
(2013)
ISME J.
, vol.7
, pp. 1016-1025
-
-
Abusleme, L.1
Dupuy, A.K.2
Dutzan, N.3
Silva, N.4
Burleson, J.A.5
Strausbaugh, L.D.6
Gamonal, J.7
Diaz, P.I.8
-
31
-
-
84875990477
-
Complement in immune and inflammatory disorders: Therapeutic interventions
-
Ricklin, D., and J. D. Lambris. 2013. Complement in immune and inflammatory disorders: therapeutic interventions. J. Immunol. 190:3839-3847.
-
(2013)
J. Immunol.
, vol.190
, pp. 3839-3847
-
-
Ricklin, D.1
Lambris, J.D.2
-
32
-
-
0021949676
-
Morphological studies on periodontal disease in the cynomolgus monkey. II. Light microscopic observations on ligature-induced periodontitis
-
Brecx, M. C., J. Nalbandian, K. Ooya, K. S. Kornman, and P. B. Robertson. 1985. Morphological studies on periodontal disease in the cynomolgus monkey. II. Light microscopic observations on ligature-induced periodontitis. J. Periodontal Res. 20:165-175.
-
(1985)
J. Periodontal Res.
, vol.20
, pp. 165-175
-
-
Brecx, M.C.1
Nalbandian, J.2
Ooya, K.3
Kornman, K.S.4
Robertson, P.B.5
-
34
-
-
0019443764
-
The microbiology of ligature-induced periodontitis in the cynomolgus monkey
-
Kornman, K. S., S. C. Holt, and P. B. Robertson. 1981. The microbiology of ligature-induced periodontitis in the cynomolgus monkey. J. Periodontal Res. 16:363-371.
-
(1981)
J. Periodontal Res.
, vol.16
, pp. 363-371
-
-
Kornman, K.S.1
Holt, S.C.2
Robertson, P.B.3
-
35
-
-
0031908674
-
IL-1 and TNF antagonists inhibit the inflammatory response and bone loss in experimental periodontitis
-
Assuma, R., T. Oates, D. Cochran, S. Amar, and D. T. Graves. 1998. IL-1 and TNF antagonists inhibit the inflammatory response and bone loss in experimental periodontitis. J. Immunol. 160:403-409.
-
(1998)
J. Immunol.
, vol.160
, pp. 403-409
-
-
Assuma, R.1
Oates, T.2
Cochran, D.3
Amar, S.4
Graves, D.T.5
-
36
-
-
84875244143
-
New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties
-
Qu, H., D. Ricklin, H. Bai, H. Chen, E. S. Reis, M. Maciejewski, A. Tzekou, R. A. De Angelis, R. R. Resuello, F. Lupu, et al. 2013. New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties. Immunobiology 218:496-505.
-
(2013)
Immunobiology
, vol.218
, pp. 496-505
-
-
Qu, H.1
Ricklin, D.2
Bai, H.3
Chen, H.4
Reis, E.S.5
Maciejewski, M.6
Tzekou, A.7
De Angelis, R.A.8
Resuello, R.R.9
Lupu, F.10
-
37
-
-
0033062148
-
Genetic disruption of the murine complement C3 promoter region generates deficient mice with extrahepatic expression of C3 mRNA
-
Circolo, A., G. Garnier, W. Fukuda, X. Wang, T. Hidvegi, A. J. Szalai, D. E. Briles, J. E. Volanakis, R. A. Wetsel, and H. R. Colten. 1999. Genetic disruption of the murine complement C3 promoter region generates deficient mice with extrahepatic expression of C3 mRNA. Immunopharmacology 42:135-149.
-
(1999)
Immunopharmacology
, vol.42
, pp. 135-149
-
-
Circolo, A.1
Garnier, G.2
Fukuda, W.3
Wang, X.4
Hidvegi, T.5
Szalai, A.J.6
Briles, D.E.7
Volanakis, J.E.8
Wetsel, R.A.9
Colten, H.R.10
-
38
-
-
0029795542
-
The C5a chemoattractant receptor mediates mucosal defence to infection
-
Höpken, U. E., B. Lu, N. P. Gerard, and C. Gerard. 1996. The C5a chemoattractant receptor mediates mucosal defence to infection. Nature 383:86-89.
-
(1996)
Nature
, vol.383
, pp. 86-89
-
-
Höpken, U.E.1
Lu, B.2
Gerard, N.P.3
Gerard, C.4
-
39
-
-
0033801979
-
Genetic control of susceptibility to Porphyromonas gingivalis-induced alveolar bone loss in mice
-
Baker, P. J., M. Dixon, and D. C. Roopenian. 2000. Genetic control of susceptibility to Porphyromonas gingivalis-induced alveolar bone loss in mice. Infect. Immun. 68:5864-5868.
-
(2000)
Infect. Immun.
, vol.68
, pp. 5864-5868
-
-
Baker, P.J.1
Dixon, M.2
Roopenian, D.C.3
-
40
-
-
84869029797
-
Inhibition of Porphyromonas gingivalis-induced periodontal bone loss by CXCR4 antagonist treatment
-
McIntosh, M. L., and G. Hajishengallis. 2012. Inhibition of Porphyromonas gingivalis-induced periodontal bone loss by CXCR4 antagonist treatment. Mol. Oral Microbiol. 27:449-457.
-
(2012)
Mol. Oral Microbiol.
, vol.27
, pp. 449-457
-
-
McIntosh, M.L.1
Hajishengallis, G.2
-
41
-
-
38149006156
-
The use of rodent models to investigate host-bacteria interactions related to periodontal diseases
-
Graves, D. T., D. Fine, Y. T. Teng, T. E. Van Dyke, and G. Hajishengallis. 2008. The use of rodent models to investigate host-bacteria interactions related to periodontal diseases. J. Clin. Periodontol. 35:89-105.
-
(2008)
J. Clin. Periodontol.
, vol.35
, pp. 89-105
-
-
Graves, D.T.1
Fine, D.2
Teng, Y.T.3
Van Dyke, T.E.4
Hajishengallis, G.5
-
42
-
-
84880046627
-
Optimization of the ligature-induced periodontitis model in mice
-
Abe, T., and G. Hajishengallis. 2013. Optimization of the ligature-induced periodontitis model in mice. J. Immunol. Methods 394:49-54.
-
(2013)
J. Immunol. Methods
, vol.394
, pp. 49-54
-
-
Abe, T.1
Hajishengallis, G.2
-
43
-
-
0028409885
-
Macaca fascicularis as a model in which to assess the safety and efficacy of a vaccine for periodontitis
-
Persson, G. R., L. D. Engel, C. W. Whitney, A. Weinberg, B. J. Moncla, R. P. Darveau, L. Houston, P. Braham, and R. C. Page. 1994. Macaca fascicularis as a model in which to assess the safety and efficacy of a vaccine for periodontitis. Oral Microbiol. Immunol. 9:104-111.
-
(1994)
Oral Microbiol. Immunol.
, vol.9
, pp. 104-111
-
-
Persson, G.R.1
Engel, L.D.2
Whitney, C.W.3
Weinberg, A.4
Moncla, B.J.5
Darveau, R.P.6
Houston, L.7
Braham, P.8
Page, R.C.9
-
44
-
-
1542507065
-
Periodontal diagnoses and classification of periodontal diseases
-
Armitage, G. C. 2004. Periodontal diagnoses and classification of periodontal diseases. Periodontol. 2000 34:9-21.
-
(2004)
Periodontol. 2000
, vol.34
, pp. 9-21
-
-
Armitage, G.C.1
-
45
-
-
79251502922
-
Antibody to receptor activator of NF-κB ligand ameliorates T cell-mediated periodontal bone resorption
-
Lin, X., X. Han, T. Kawai, and M. A. Taubman. 2011. Antibody to receptor activator of NF-κB ligand ameliorates T cell-mediated periodontal bone resorption. Infect. Immun. 79:911-917.
-
(2011)
Infect. Immun.
, vol.79
, pp. 911-917
-
-
Lin, X.1
Han, X.2
Kawai, T.3
Taubman, M.A.4
-
46
-
-
34247392923
-
Gingival crevicular fluid levels of RANKL and OPG in periodontal diseases: Implications of their relative ratio
-
Bostanci, N., T. Ilgenli, G. Emingil, B. Afacan, B. Han, H. Töz, G. Atilla, F. J. Hughes, and G. N. Belibasakis. 2007. Gingival crevicular fluid levels of RANKL and OPG in periodontal diseases: implications of their relative ratio. J. Clin. Periodontol. 34:370-376.
-
(2007)
J. Clin. Periodontol.
, vol.34
, pp. 370-376
-
-
Bostanci, N.1
Ilgenli, T.2
Emingil, G.3
Afacan, B.4
Han, B.5
Töz, H.6
Atilla, G.7
Hughes, F.J.8
Belibasakis, G.N.9
-
47
-
-
79251544574
-
The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss
-
Liang, S., J. L. Krauss, H. Domon, M. L. McIntosh, K. B. Hosur, H. Qu, F. Li, A. Tzekou, J. D. Lambris, and G. Hajishengallis. 2011. The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss. J. Immunol. 186:869-877.
-
(2011)
J. Immunol.
, vol.186
, pp. 869-877
-
-
Liang, S.1
Krauss, J.L.2
Domon, H.3
McIntosh, M.L.4
Hosur, K.B.5
Qu, H.6
Li, F.7
Tzekou, A.8
Lambris, J.D.9
Hajishengallis, G.10
-
48
-
-
0026725842
-
Activation of complement components C3 and C5 by a cysteine proteinase (gingipain-1) from Porphyromonas (Bacteroides) gingivalis
-
Wingrove, J. A., R. G. Di Scipio, Z. Chen, J. Potempa, J. Travis, and T. E. Hugli. 1992. Activation of complement components C3 and C5 by a cysteine proteinase (gingipain-1) from Porphyromonas (Bacteroides) gingivalis. J. Biol. Chem. 267:18902-18907.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 18902-18907
-
-
Wingrove, J.A.1
Di Scipio, R.G.2
Chen, Z.3
Potempa, J.4
Travis, J.5
Hugli, T.E.6
-
49
-
-
38049148318
-
Dietinduced obesity in mice causes changes in immune responses and bone loss manifested by bacterial challenge
-
Amar, S., Q. Zhou, Y. Shaik-Dasthagirisaheb, and S. Leeman. 2007. Dietinduced obesity in mice causes changes in immune responses and bone loss manifested by bacterial challenge. Proc. Natl. Acad. Sci. USA 104:20466-20471.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 20466-20471
-
-
Amar, S.1
Zhou, Q.2
Shaik-Dasthagirisaheb, Y.3
Leeman, S.4
-
50
-
-
84901611214
-
Aging and its impact on innate immunity and inflammation: Implications for periodontitis
-
Hajishengallis, G. 2014. Aging and its impact on innate immunity and inflammation: Implications for periodontitis. J. Oral Biosci. 56:30-37.
-
(2014)
J. Oral Biosci.
, vol.56
, pp. 30-37
-
-
Hajishengallis, G.1
-
51
-
-
84863393385
-
The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss
-
Eskan, M. A., R. Jotwani, T. Abe, J. Chmelar, J. H. Lim, S. Liang, P. A. Ciero, J. L. Krauss, F. Li, M. Rauner, et al. 2012. The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss. Nat. Immunol. 13:465-473.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 465-473
-
-
Eskan, M.A.1
Jotwani, R.2
Abe, T.3
Chmelar, J.4
Lim, J.H.5
Liang, S.6
Ciero, P.A.7
Krauss, J.L.8
Li, F.9
Rauner, M.10
-
52
-
-
84866934694
-
Targeting IL-17 and TH17 cells in chronic inflammation
-
Miossec, P., and J. K. Kolls. 2012. Targeting IL-17 and TH17 cells in chronic inflammation. Nat. Rev. Drug Discov. 11:763-776.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 763-776
-
-
Miossec, P.1
Kolls, J.K.2
-
53
-
-
84862250915
-
Inhibition of cathepsin K for treatment of osteoporosis
-
Boonen, S., E. Rosenberg, F. Claessens, D. Vanderschueren, and S. Papapoulos. 2012. Inhibition of cathepsin K for treatment of osteoporosis. Curr. Osteoporos. Rep. 10:73-79.
-
(2012)
Curr. Osteoporos. Rep.
, vol.10
, pp. 73-79
-
-
Boonen, S.1
Rosenberg, E.2
Claessens, F.3
Vanderschueren, D.4
Papapoulos, S.5
-
54
-
-
84874457770
-
Genomic responses in mouse models poorly mimic human inflammatory diseases
-
Inflammation and Host Response to Injury, Large Scale Collaborative Research Program
-
Inflammation and Host Response to Injury, Large Scale Collaborative Research Program. 2013. Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc. Natl. Acad. Sci. USA 110:3507-3512.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 3507-3512
-
-
-
55
-
-
77950187449
-
Crosstalk pathways between Tolllike receptors and the complement system
-
Hajishengallis, G., and J. D. Lambris. 2010. Crosstalk pathways between Tolllike receptors and the complement system. Trends Immunol. 31:154-163.
-
(2010)
Trends Immunol.
, vol.31
, pp. 154-163
-
-
Hajishengallis, G.1
Lambris, J.D.2
-
56
-
-
34347400796
-
Regulation of Toll-like receptormediated inflammatory response by complement in vivo
-
Zhang, X., Y. Kimura, C. Fang, L. Zhou, G. Sfyroera, J. D. Lambris, R. A. Wetsel, T. Miwa, and W. C. Song. 2007. Regulation of Toll-like receptormediated inflammatory response by complement in vivo. Blood 110:228-236.
-
(2007)
Blood
, vol.110
, pp. 228-236
-
-
Zhang, X.1
Kimura, Y.2
Fang, C.3
Zhou, L.4
Sfyroera, G.5
Lambris, J.D.6
Wetsel, R.A.7
Miwa, T.8
Song, W.C.9
-
57
-
-
33947629255
-
Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors
-
Miyake, K. 2007. Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors. Semin. Immunol. 19:3-10.
-
(2007)
Semin. Immunol.
, vol.19
, pp. 3-10
-
-
Miyake, K.1
-
58
-
-
77949683133
-
Extracellular matrix molecules: Endogenous danger signals as new drug targets in kidney diseases
-
Schaefer, L. 2010. Extracellular matrix molecules: endogenous danger signals as new drug targets in kidney diseases. Curr. Opin. Pharmacol. 10:185-190.
-
(2010)
Curr. Opin. Pharmacol.
, vol.10
, pp. 185-190
-
-
Schaefer, L.1
-
59
-
-
84866050890
-
Complement and dysbiosis in periodontal disease
-
Hajishengallis, G., and J. D. Lambris. 2012. Complement and dysbiosis in periodontal disease. Immunobiology 217:1111-1116.
-
(2012)
Immunobiology
, vol.217
, pp. 1111-1116
-
-
Hajishengallis, G.1
Lambris, J.D.2
-
60
-
-
84862081068
-
Complement C3ainduced IL-17 plays a critical role in an IgE-mediated late-phase asthmatic response and airway hyperresponsiveness via neutrophilic inflammation in mice
-
Mizutani, N., H. Goshima, T. Nabe, and S. Yoshino. 2012. Complement C3ainduced IL-17 plays a critical role in an IgE-mediated late-phase asthmatic response and airway hyperresponsiveness via neutrophilic inflammation in mice. J. Immunol. 188:5694-5705.
-
(2012)
J. Immunol.
, vol.188
, pp. 5694-5705
-
-
Mizutani, N.1
Goshima, H.2
Nabe, T.3
Yoshino, S.4
-
61
-
-
79960559299
-
Complement component C5a promotes expression of IL-22 and IL-17 from human T cells and its implication in agerelated macular degeneration
-
Liu, B., L. Wei, C. Meyerle, J. Tuo, H. N. Sen, Z. Li, S. Chakrabarty, E. Agron, C. C. Chan, M. L. Klein, et al. 2011. Complement component C5a promotes expression of IL-22 and IL-17 from human T cells and its implication in agerelated macular degeneration. J. Transl. Med. 9:1-12.
-
(2011)
J. Transl. Med.
, vol.9
, pp. 1-12
-
-
Liu, B.1
Wei, L.2
Meyerle, C.3
Tuo, J.4
Sen, H.N.5
Li, Z.6
Chakrabarty, S.7
Agron, E.8
Chan, C.C.9
Klein, M.L.10
-
62
-
-
77951028450
-
Complement C5a regulates IL-17 by affecting the crosstalk between DC and gammadelta T cells in CLP-induced sepsis
-
Xu, R., R. Wang, G. Han, J. Wang, G. Chen, L. Wang, X. Li, R. Guo, B. Shen, and Y. Li. 2010. Complement C5a regulates IL-17 by affecting the crosstalk between DC and gammadelta T cells in CLP-induced sepsis. Eur. J. Immunol. 40:1079-1088.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 1079-1088
-
-
Xu, R.1
Wang, R.2
Han, G.3
Wang, J.4
Chen, G.5
Wang, L.6
Li, X.7
Guo, R.8
Shen, B.9
Li, Y.10
-
63
-
-
77956955243
-
Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma
-
Lajoie, S., I. P. Lewkowich, Y. Suzuki, J. R. Clark, A. A. Sproles, K. Dienger, A. L. Budelsky, and M. Wills-Karp. 2010. Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma. Nat. Immunol. 11:928-935.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 928-935
-
-
Lajoie, S.1
Lewkowich, I.P.2
Suzuki, Y.3
Clark, J.R.4
Sproles, A.A.5
Dienger, K.6
Budelsky, A.L.7
Wills-Karp, M.8
-
64
-
-
84860902599
-
Evidence for anti-inflammatory effects of C5a on the innate IL-17A/IL-23 axis
-
Bosmann, M., J. V. Sarma, G. Atefi, F. S. Zetoune, and P. A. Ward. 2012. Evidence for anti-inflammatory effects of C5a on the innate IL-17A/IL-23 axis. FASEB J. 26:1640-1651.
-
(2012)
FASEB J.
, vol.26
, pp. 1640-1651
-
-
Bosmann, M.1
Sarma, J.V.2
Atefi, G.3
Zetoune, F.S.4
Ward, P.A.5
-
65
-
-
84860389426
-
Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1b
-
Ignatius, A., P. Schoengraf, L. Kreja, A. Liedert, S. Recknagel, S. Kandert, R. E. Brenner, M. Schneider, J. D. Lambris, and M. Huber-Lang. 2011. Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1b. J. Cell. Biochem. 112:2594-2605.
-
(2011)
J. Cell. Biochem.
, vol.112
, pp. 2594-2605
-
-
Ignatius, A.1
Schoengraf, P.2
Kreja, L.3
Liedert, A.4
Recknagel, S.5
Kandert, S.6
Brenner, R.E.7
Schneider, M.8
Lambris, J.D.9
Huber-Lang, M.10
-
66
-
-
84856591543
-
The RANKL-OPG system in clinical periodontology
-
Belibasakis, G. N., and N. Bostanci. 2012. The RANKL-OPG system in clinical periodontology. J. Clin. Periodontol. 39:239-248.
-
(2012)
J. Clin. Periodontol.
, vol.39
, pp. 239-248
-
-
Belibasakis, G.N.1
Bostanci, N.2
-
67
-
-
72249104320
-
Complementary Tolls in the periodontium: How periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host
-
Krauss, J. L., J. Potempa, J. D. Lambris, and G. Hajishengallis. 2010. Complementary Tolls in the periodontium: how periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host. Periodontol. 2000 52:141-162.
-
(2010)
Periodontol. 2000
, vol.52
, pp. 141-162
-
-
Krauss, J.L.1
Potempa, J.2
Lambris, J.D.3
Hajishengallis, G.4
-
68
-
-
61449163214
-
Corruption of innate immunity by bacterial proteases
-
Potempa, J., and R. N. Pike. 2009. Corruption of innate immunity by bacterial proteases. J. Innate Immun. 1:70-87.
-
(2009)
J. Innate Immun.
, vol.1
, pp. 70-87
-
-
Potempa, J.1
Pike, R.N.2
-
69
-
-
63149173182
-
Analysis of a unique interaction between the complement regulatory protein factor H and the periodontal pathogen Treponema denticola
-
McDowell, J. V., B. Huang, J. C. Fenno, and R. T. Marconi. 2009. Analysis of a unique interaction between the complement regulatory protein factor H and the periodontal pathogen Treponema denticola. Infect. Immun. 77:1417-1425.
-
(2009)
Infect. Immun.
, vol.77
, pp. 1417-1425
-
-
McDowell, J.V.1
Huang, B.2
Fenno, J.C.3
Marconi, R.T.4
-
70
-
-
84857463226
-
A metalloproteinase karilysin present in the majority of Tannerella forsythia isolates inhibits all pathways of the complement system
-
Jusko, M., J. Potempa, A. Y. Karim, M. Ksiazek, K. Riesbeck, P. Garred, S. Eick, and A. M. Blom. 2012. A metalloproteinase karilysin present in the majority of Tannerella forsythia isolates inhibits all pathways of the complement system. J. Immunol. 188:2338-2349.
-
(2012)
J. Immunol.
, vol.188
, pp. 2338-2349
-
-
Jusko, M.1
Potempa, J.2
Karim, A.Y.3
Ksiazek, M.4
Riesbeck, K.5
Garred, P.6
Eick, S.7
Blom, A.M.8
-
71
-
-
34249799593
-
Biphasic effect of gingipains from Porphyromonas gingivalis on the human complement system
-
Popadiak, K., J. Potempa, K. Riesbeck, and A. M. Blom. 2007. Biphasic effect of gingipains from Porphyromonas gingivalis on the human complement system. J. Immunol. 178:7242-7250.
-
(2007)
J. Immunol.
, vol.178
, pp. 7242-7250
-
-
Popadiak, K.1
Potempa, J.2
Riesbeck, K.3
Blom, A.M.4
-
72
-
-
84877871524
-
Induction of bone loss by pathobiont-mediated Nod1 signaling in the oral cavity
-
Jiao, Y., Y. Darzi, K. Tawaratsumida, J. T. Marchesan, M. Hasegawa, H. Moon, G. Y. Chen, G. Núñez, W. V. Giannobile, J. Raes, and N. Inohara. 2013. Induction of bone loss by pathobiont-mediated Nod1 signaling in the oral cavity. Cell Host Microbe 13:595-601.
-
(2013)
Cell Host Microbe
, vol.13
, pp. 595-601
-
-
Jiao, Y.1
Darzi, Y.2
Tawaratsumida, K.3
Marchesan, J.T.4
Hasegawa, M.5
Moon, H.6
Chen, G.Y.7
Núñez, G.8
Giannobile, W.V.9
Raes, J.10
Inohara, N.11
-
73
-
-
84893587232
-
Breaking bad: Manipulation of the host response by Porphyromonas gingivalis
-
Hajishengallis, G., and R. J. Lamont. 2014. Breaking bad: manipulation of the host response by Porphyromonas gingivalis. Eur. J. Immunol. 44:328-338.
-
(2014)
Eur. J. Immunol.
, vol.44
, pp. 328-338
-
-
Hajishengallis, G.1
Lamont, R.J.2
-
74
-
-
0037292394
-
Are dental diseases examples of ecological catastrophes?
-
Marsh, P. D. 2003. Are dental diseases examples of ecological catastrophes? Microbiology 149:279-294.
-
(2003)
Microbiology
, vol.149
, pp. 279-294
-
-
Marsh, P.D.1
-
75
-
-
84897542244
-
Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria
-
Risitano, A. M., D. Ricklin, Y. Huang, E. S. Reis, H. Chen, P. Ricci, Z. Lin, C. Pascariello, M. Raia, M. Sica, et al. 2014. Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria. Blood 123:2094-2101
-
(2014)
Blood
, vol.123
, pp. 2094-2101
-
-
Risitano, A.M.1
Ricklin, D.2
Huang, Y.3
Reis, E.S.4
Chen, H.5
Ricci, P.6
Lin, Z.7
Pascariello, C.8
Raia, M.9
Sica, M.10
|