The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss

Journal of Immunology

Volumn 186, Issue 2, 2011, Pages 869-877

  Liang, Shuang ^a   Krauss, Jennifer L ^a,b   Domon, Hisanori ^a,d   McIntosh, Megan L ^a,b   Hosur, Kavita B ^a,e   Qu, Hongchang ^c   Li, Fenge ^a   Tzekou, Apostolia ^c   Lambris, John D ^c   Hajishengallis, George ^a,b  

^a UNIVERSITY OF LOUISVILLE SCHOOL OF MEDICINE   (United States)

^b University of Louisville School of Medicine   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d NIIGATA UNIVERSITY   (Japan)

^e UNIVERSITY OF PENNSYLVANIA SCHOOL OF DENTAL MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; INTERLEUKIN 12P70; INTERLEUKIN 1BETA; INTERLEUKIN 6; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA;

ADAPTIVE IMMUNITY; ALVEOLAR BONE LOSS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; IMMUNE EVASION; IN VIVO STUDY; MACROPHAGE; MOUSE; NONHUMAN; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ALVEOLAR BONE LOSS; ANIMALS; DISEASE MODELS, ANIMAL; IMMUNE EVASION; INFLAMMATION MEDIATORS; INTERLEUKIN-10; INTERLEUKIN-12; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID DIFFERENTIATION FACTOR 88; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; RECEPTOR CROSS-TALK; RECEPTOR, ANAPHYLATOXIN C5A; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2;

EID: 79251544574     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1003252     Document Type: Article

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