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Volumn 3, Issue 1, 2014, Pages 61-78

Genetic Epidemiology of Psoriasis

Author keywords

Epidemiology; Genetic; Pathogenesis; Prevalence; Psoriasis

Indexed keywords

ANTIMALARIAL AGENT; ANTIPSORIASIS AGENT; ANXIOLYTIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CLONIDINE; DIGOXIN; FLUOXETINE; HLA ANTIGEN; HLA B ANTIGEN; HLA B13 ANTIGEN; HLA B57 ANTIGEN; HLA C ANTIGEN; HLA CW2 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON; INTERLEUKIN 12P40; INTERLEUKIN 13; INTERLEUKIN 23 RECEPTOR; INTERLEUKIN 4; LITHIUM; METHOTREXATE; NEUROLEPTIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; PROTEIN TYROSINE KINASE; STAT2 PROTEIN; TETRACYCLINE; TUMOR NECROSIS FACTOR INHIBITOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84942925053     PISSN: None     EISSN: 21624933     Source Type: Journal    
DOI: 10.1007/s13671-013-0066-6     Document Type: Review
Times cited : (100)

References (173)
  • 1
    • 0029887202 scopus 로고    scopus 로고
    • Population-based epidemiologic study of psoriasis with emphasis on quality of life assessment
    • Koo J. Population-based epidemiologic study of psoriasis with emphasis on quality of life assessment. Dermatol Clin. 1996;14(3): 485-96.
    • (1996) Dermatol Clin , vol.14 , Issue.3 , pp. 485-496
    • Koo, J.1
  • 2
    • 68049131637 scopus 로고    scopus 로고
    • Psoriasis
    • doi:10.1056/NEJMra0804595
    • Nestle FO, Kaplan DH, Barker J. Psoriasis. N Engl J Med. 2009;361(5): 496-509. doi: 10. 1056/NEJMra0804595.
    • (2009) N Engl J Med , vol.361 , Issue.5 , pp. 496-509
    • Nestle, F.O.1    Kaplan, D.H.2    Barker, J.3
  • 3
    • 1842555395 scopus 로고    scopus 로고
    • Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction
    • doi:10.1046/j.1087-0024.2003.09102.x
    • Stern RS, Nijsten T, Feldman SR, Margolis DJ, Rolstad T. Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction. J Investig Dermatol Symp Proc. 2004;9(2): 136-9. doi: 10. 1046/j. 1087-0024. 2003. 09102. x.
    • (2004) J Investig Dermatol Symp Proc , vol.9 , Issue.2 , pp. 136-139
    • Stern, R.S.1    Nijsten, T.2    Feldman, S.R.3    Margolis, D.J.4    Rolstad, T.5
  • 4
    • 77649186719 scopus 로고    scopus 로고
    • Geoepidemiology and environmental factors of psoriasis and psoriatic arthritis
    • doi:10.1016/j.jaut.2009.12.001
    • Chandran V, Raychaudhuri SP. Geoepidemiology and environmental factors of psoriasis and psoriatic arthritis. J Autoimmun. 2010;34(3): J314-21. doi: 10. 1016/j. jaut. 2009. 12. 001.
    • (2010) J Autoimmun , vol.34 , Issue.3
    • Chandran, V.1    Raychaudhuri, S.P.2
  • 5
    • 0035724176 scopus 로고    scopus 로고
    • Psoriasis-epidemiology and clinical spectrum
    • Christophers E. Psoriasis-epidemiology and clinical spectrum. Clin Exp Dermatol. 2001;26(4): 314-20.
    • (2001) Clin Exp Dermatol , vol.26 , Issue.4 , pp. 314-320
    • Christophers, E.1
  • 6
    • 59149098800 scopus 로고    scopus 로고
    • Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis
    • doi:10.1038/ng.313
    • de Cid R, Riveira-Munoz E, Zeeuwen PL, Robarge J, Liao W, Dannhauser EN, et al. Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis. Nat Genet. 2009;41(2): 211-5. doi: 10. 1038/ng. 313.
    • (2009) Nat Genet , vol.41 , Issue.2 , pp. 211-215
    • de Cid, R.1    Riveira-Munoz, E.2    Zeeuwen, P.L.3    Robarge, J.4    Liao, W.5    Dannhauser, E.N.6
  • 7
    • 84859509159 scopus 로고    scopus 로고
    • Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci
    • doi:10.1016/j.ajhg.2012.02.020
    • Ellinghaus D, Ellinghaus E, Nair RP, Stuart PE, Esko T, Metspalu A, et al. Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci. Am J Human Genet. 2012;90(4): 636-47. doi: 10. 1016/j. ajhg. 2012. 02. 020.
    • (2012) Am J Human Genet , vol.90 , Issue.4 , pp. 636-647
    • Ellinghaus, D.1    Ellinghaus, E.2    Nair, R.P.3    Stuart, P.E.4    Esko, T.5    Metspalu, A.6
  • 8
    • 78049343768 scopus 로고    scopus 로고
    • Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
    • doi:10.1038/ng.689
    • Ellinghaus E, Ellinghaus D, Stuart PE, Nair RP, Debrus S, Raelson JV, et al. Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2. Nat Genet. 2010;42(11): 991-5. doi: 10. 1038/ng. 689.
    • (2010) Nat Genet , vol.42 , Issue.11 , pp. 991-995
    • Ellinghaus, E.1    Ellinghaus, D.2    Stuart, P.E.3    Nair, R.P.4    Debrus, S.5    Raelson, J.V.6
  • 9
    • 59149106117 scopus 로고    scopus 로고
    • Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways
    • doi:10.1038/ng.311
    • Nair RP, Duffin KC, Helms C, Ding J, Stuart PE, Goldgar D, et al. Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Nat Genet. 2009;41(2): 199-204. doi: 10. 1038/ng. 311.
    • (2009) Nat Genet , vol.41 , Issue.2 , pp. 199-204
    • Nair, R.P.1    Duffin, K.C.2    Helms, C.3    Ding, J.4    Stuart, P.E.5    Goldgar, D.6
  • 10
    • 78049347495 scopus 로고    scopus 로고
    • A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
    • Genetic Analysis of Psoriasis C, the Wellcome Trust Case Control C, doi:10.1038/ng.694
    • Genetic Analysis of Psoriasis C, the Wellcome Trust Case Control C, Strange A, Capon F, Spencer CC, Knight J, et al. A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet. 2010;42(11): 985-90. doi: 10. 1038/ng. 694.
    • (2010) Nat Genet , vol.42 , Issue.11 , pp. 985-990
    • Strange, A.1    Capon, F.2    Spencer, C.C.3    Knight, J.4
  • 11
    • 78049323656 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies three psoriasis susceptibility loci
    • doi:10.1038/ng.693
    • Stuart PE, Nair RP, Ellinghaus E, Ding J, Tejasvi T, Gudjonsson JE, et al. Genome-wide association analysis identifies three psoriasis susceptibility loci. Nat Genet. 2010;42(11): 1000-4. doi: 10. 1038/ng. 693.
    • (2010) Nat Genet , vol.42 , Issue.11 , pp. 1000-1004
    • Stuart, P.E.1    Nair, R.P.2    Ellinghaus, E.3    Ding, J.4    Tejasvi, T.5    Gudjonsson, J.E.6
  • 12
    • 78049329814 scopus 로고    scopus 로고
    • Association analyses identify six new psoriasis susceptibility loci in the Chinese population
    • doi:10.1038/ng.690
    • Sun LD, Cheng H, Wang ZX, Zhang AP, Wang PG, Xu JH, et al. Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat Genet. 2010;42(11): 1005-9. doi: 10. 1038/ng. 690.
    • (2010) Nat Genet , vol.42 , Issue.11 , pp. 1005-1009
    • Sun, L.D.1    Cheng, H.2    Wang, Z.X.3    Zhang, A.P.4    Wang, P.G.5    Xu, J.H.6
  • 13
    • 84870512735 scopus 로고    scopus 로고
    • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
    • An article that performed meta-analysis of GWAS studies and two datasets genotyped on immunochip and presented a list of 36 genetic loci, including 15 new, associated with psoriasis, doi:10.1038/ng.2467
    • Tsoi LC, Spain SL, Knight J, Ellinghaus E, Stuart PE, Capon F, et al. Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat Genet. 2012;44(12): 1341-8. doi: 10. 1038/ng. 2467. An article that performed meta-analysis of GWAS studies and two datasets genotyped on immunochip and presented a list of 36 genetic loci, including 15 new, associated with psoriasis.
    • (2012) Nat Genet , vol.44 , Issue.12 , pp. 1341-1348
    • Tsoi, L.C.1    Spain, S.L.2    Knight, J.3    Ellinghaus, E.4    Stuart, P.E.5    Capon, F.6
  • 14
    • 59149096149 scopus 로고    scopus 로고
    • Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21
    • doi: 10. 1038/ng. 310
    • Zhang XJ, Huang W, Yang S, Sun LD, Zhang FY, Zhu QX et al. Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. Nat Genet. 2009;41(2): 205-10. doi: 10. 1038/ng. 310.
    • (2009) Nat Genet. , vol.41 , Issue.2 , pp. 205-210
    • Zhang, X.J.1    Huang, W.2    Yang, S.3    Sun, L.D.4    Zhang, F.Y.5    Zhu, Q.X.6
  • 15
    • 0021806161 scopus 로고
    • Psoriasis of early and late onset: characterization of two types of psoriasis vulgaris
    • Henseler T, Christophers E. Psoriasis of early and late onset: characterization of two types of psoriasis vulgaris. J Am Acad Dermatol. 1985;13(3): 450-6.
    • (1985) J Am Acad Dermatol , vol.13 , Issue.3 , pp. 450-456
    • Henseler, T.1    Christophers, E.2
  • 16
    • 0024851722 scopus 로고
    • Patient subgroups and the inflammatory pattern in psoriasis
    • discussion 106-10
    • Christophers E, Henseler T. Patient subgroups and the inflammatory pattern in psoriasis. Acta Derm Venereol Suppl. 1989;151: 88-92. discussion 106-10.
    • (1989) Acta Derm Venereol Suppl , vol.151 , pp. 88-92
    • Christophers, E.1    Henseler, T.2
  • 18
    • 43449137849 scopus 로고    scopus 로고
    • National Psoriasis Foundation clinical consensus on psoriasis comorbidities and recommendations for screening
    • doi:10.1016/j.jaad.2008.01.006
    • Kimball AB, Gladman D, Gelfand JM, Gordon K, Horn EJ, Korman NJ, et al. National Psoriasis Foundation clinical consensus on psoriasis comorbidities and recommendations for screening. J Am Acad Dermatol. 2008;58(6): 1031-42. doi: 10. 1016/j. jaad. 2008. 01. 006.
    • (2008) J Am Acad Dermatol , vol.58 , Issue.6 , pp. 1031-1042
    • Kimball, A.B.1    Gladman, D.2    Gelfand, J.M.3    Gordon, K.4    Horn, E.J.5    Korman, N.J.6
  • 19
    • 33749613119 scopus 로고    scopus 로고
    • Risk of myocardial infarction in patients with psoriasis
    • doi:10.1001/jama.296.14.1735
    • Gelfand JM, Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB. Risk of myocardial infarction in patients with psoriasis. JAMA. 2006;296(14): 1735-41. doi: 10. 1001/jama. 296. 14. 1735.
    • (2006) Jama , vol.296 , Issue.14 , pp. 1735-1741
    • Gelfand, J.M.1    Neimann, A.L.2    Shin, D.B.3    Wang, X.4    Margolis, D.J.5    Troxel, A.B.6
  • 20
    • 64849085648 scopus 로고    scopus 로고
    • Psoriasis and risk of incident myocardial infarction, stroke or transient ischaemic attack: an inception cohort study with a nested case-control analysis
    • doi:10.1111/j.1365-2133.2008.09020.x
    • Brauchli YB, Jick SS, Miret M, Meier CR. Psoriasis and risk of incident myocardial infarction, stroke or transient ischaemic attack: an inception cohort study with a nested case-control analysis. Br J Dermatol. 2009;160(5): 1048-56. doi: 10. 1111/j. 1365-2133. 2008. 09020. x.
    • (2009) Br J Dermatol , vol.160 , Issue.5 , pp. 1048-1056
    • Brauchli, Y.B.1    Jick, S.S.2    Miret, M.3    Meier, C.R.4
  • 21
    • 70349960058 scopus 로고    scopus 로고
    • Prevalence of myocardial infarction in patients with psoriasis in central China
    • doi:10.1111/j.1468-3083.2009.03318.x
    • Xiao J, Chen LH, Tu YT, Deng XH, Tao J. Prevalence of myocardial infarction in patients with psoriasis in central China. J Eur Acad Dermatol Venereol. 2009;23(11): 1311-5. doi: 10. 1111/j. 1468-3083. 2009. 03318. x.
    • (2009) J Eur Acad Dermatol Venereol , vol.23 , Issue.11 , pp. 1311-1315
    • Xiao, J.1    Chen, L.H.2    Tu, Y.T.3    Deng, X.H.4    Tao, J.5
  • 22
    • 79960208264 scopus 로고    scopus 로고
    • Psoriasis is associated with clinically significant cardiovascular risk: a Danish nationwide cohort study
    • This study showed that patients with psoriasis had an increased risk of cardiovascular events and all-cause mortality and that these risks increased with disease severity, doi:10.1111/j.1365-2796.2010.02310.x
    • Ahlehoff O, Gislason GH, Charlot M, Jorgensen CH, Lindhardsen J, Olesen JB, et al. Psoriasis is associated with clinically significant cardiovascular risk: a Danish nationwide cohort study. J Intern Med. 2011;270(2): 147-57. doi: 10. 1111/j. 1365-2796. 2010. 02310. x. This study showed that patients with psoriasis had an increased risk of cardiovascular events and all-cause mortality and that these risks increased with disease severity.
    • (2011) J Intern Med , vol.270 , Issue.2 , pp. 147-157
    • Ahlehoff, O.1    Gislason, G.H.2    Charlot, M.3    Jorgensen, C.H.4    Lindhardsen, J.5    Olesen, J.B.6
  • 23
    • 84885902717 scopus 로고    scopus 로고
    • Psoriasis severity and the prevalence of major medical comorbidity: a population-based study
    • This study linked disease severity with increased risk of several comorbidities, including COPD, diabetes mellitus, mild liver disease, myocardial infarction, peptic ulcer disease, peripheral vascular disease, renal disease, and rheumatologic disease, doi:10.1001/jamadermatol.2013.5015
    • Yeung H, Takeshita J, Mehta NN, Kimmel SE, Ogdie A, Margolis DJ, et al. Psoriasis severity and the prevalence of major medical comorbidity: a population-based study. JAMA Dermatol. 2013. doi: 10. 1001/jamadermatol. 2013. 5015. This study linked disease severity with increased risk of several comorbidities, including COPD, diabetes mellitus, mild liver disease, myocardial infarction, peptic ulcer disease, peripheral vascular disease, renal disease, and rheumatologic disease.
    • (2013) JAMA Dermatol
    • Yeung, H.1    Takeshita, J.2    Mehta, N.N.3    Kimmel, S.E.4    Ogdie, A.5    Margolis, D.J.6
  • 24
    • 84869831363 scopus 로고    scopus 로고
    • Association between tumor necrosis factor inhibitor therapy and myocardial infarction risk in patients with psoriasis
    • This study showed that systemic treatments for psoriasis, including TNF inhibitors, oral medications, and even phototherapy, reduced the risk of cardiovascular events in patients with psoriasis, doi:10.1001/archdermatol.2012.2502
    • Wu JJ, Poon KY, Channual JC, Shen AY. Association between tumor necrosis factor inhibitor therapy and myocardial infarction risk in patients with psoriasis. Arch Dermatol. 2012;148(11): 1244-50. doi: 10. 1001/archdermatol. 2012. 2502. This study showed that systemic treatments for psoriasis, including TNF inhibitors, oral medications, and even phototherapy, reduced the risk of cardiovascular events in patients with psoriasis.
    • (2012) Arch Dermatol , vol.148 , Issue.11 , pp. 1244-1250
    • Wu, J.J.1    Poon, K.Y.2    Channual, J.C.3    Shen, A.Y.4
  • 25
    • 84872600519 scopus 로고    scopus 로고
    • Cardiovascular disease event rates in patients with severe psoriasis treated with systemic anti-inflammatory drugs: a Danish real-world cohort study
    • doi:10.1111/j.1365-2796.2012.02593.x
    • Ahlehoff O, Skov L, Gislason G, Lindhardsen J, Kristensen SL, Iversen L, et al. Cardiovascular disease event rates in patients with severe psoriasis treated with systemic anti-inflammatory drugs: a Danish real-world cohort study. J Intern Med. 2013;273(2): 197-204. doi: 10. 1111/j. 1365-2796. 2012. 02593. x.
    • (2013) J Intern Med , vol.273 , Issue.2 , pp. 197-204
    • Ahlehoff, O.1    Skov, L.2    Gislason, G.3    Lindhardsen, J.4    Kristensen, S.L.5    Iversen, L.6
  • 26
    • 80053070330 scopus 로고    scopus 로고
    • Increased prevalence of psychiatric disorders and health care-associated costs among patients with moderate-to-severe psoriasis
    • Han C, Lofland JH, Zhao N, Schenkel B. Increased prevalence of psychiatric disorders and health care-associated costs among patients with moderate-to-severe psoriasis. J Drugs Dermatol. 2011;10(8): 843-50.
    • (2011) J Drugs Dermatol , vol.10 , Issue.8 , pp. 843-850
    • Han, C.1    Lofland, J.H.2    Zhao, N.3    Schenkel, B.4
  • 27
    • 36048994573 scopus 로고    scopus 로고
    • Triggering psoriasis: the role of infections and medications
    • doi:10.1016/j.clindermatol.2007.08.015
    • Fry L, Baker BS. Triggering psoriasis: the role of infections and medications. Clin Dermatol. 2007;25(6): 606-15. doi: 10. 1016/j. clindermatol. 2007. 08. 015.
    • (2007) Clin Dermatol , vol.25 , Issue.6 , pp. 606-615
    • Fry, L.1    Baker, B.S.2
  • 28
    • 22144490239 scopus 로고    scopus 로고
    • Cigarette smoking, body mass index, and stressful life events as risk factors for psoriasis: results from an Italian case-control study
    • doi:10.1111/j.0022-202X.2005.23681.x
    • Naldi L, Chatenoud L, Linder D, Belloni Fortina A, Peserico A, Virgili AR, et al. Cigarette smoking, body mass index, and stressful life events as risk factors for psoriasis: results from an Italian case-control study. J Invest Dermatol. 2005;125(1): 61-7. doi: 10. 1111/j. 0022-202X. 2005. 23681. x.
    • (2005) J Invest Dermatol , vol.125 , Issue.1 , pp. 61-67
    • Naldi, L.1    Chatenoud, L.2    Linder, D.3    Belloni Fortina, A.4    Peserico, A.5    Virgili, A.R.6
  • 29
    • 73349140842 scopus 로고    scopus 로고
    • Individual differences in the effect of daily stressors on psoriasis: a prospective study
    • doi:10.1111/j.1365-2133.2009.09194.x
    • Verhoeven EW, Kraaimaat FW, de Jong EM, Schalkwijk J, van de Kerkhof PC, Evers AW. Individual differences in the effect of daily stressors on psoriasis: a prospective study. Br J Dermatol. 2009;161(2): 295-9. doi: 10. 1111/j. 1365-2133. 2009. 09194. x.
    • (2009) Br J Dermatol , vol.161 , Issue.2 , pp. 295-299
    • Verhoeven, E.W.1    Kraaimaat, F.W.2    de Jong, E.M.3    Schalkwijk, J.4    van de Kerkhof, P.C.5    Evers, A.W.6
  • 31
    • 0141923755 scopus 로고    scopus 로고
    • Psychological stress exerts an adjuvant effect on skin dendritic cell functions in vivo
    • Saint-Mezard P, Chavagnac C, Bosset S, Ionescu M, Peyron E, Kaiserlian D, et al. Psychological stress exerts an adjuvant effect on skin dendritic cell functions in vivo. J Immunol. 2003;171(8): 4073-80.
    • (2003) J Immunol , vol.171 , Issue.8 , pp. 4073-4080
    • Saint-Mezard, P.1    Chavagnac, C.2    Bosset, S.3    Ionescu, M.4    Peyron, E.5    Kaiserlian, D.6
  • 32
    • 58549112948 scopus 로고    scopus 로고
    • Relationship of psoriasis severity to obesity using same-gender siblings as controls for obesity
    • doi:10.1111/j.1365-2230.2008.02791.x
    • Murray ML, Bergstresser PR, Adams-Huet B, Cohen JB. Relationship of psoriasis severity to obesity using same-gender siblings as controls for obesity. Clin Exp Dermatol. 2009;34(2): 140-4. doi: 10. 1111/j. 1365-2230. 2008. 02791. x.
    • (2009) Clin Exp Dermatol , vol.34 , Issue.2 , pp. 140-144
    • Murray, M.L.1    Bergstresser, P.R.2    Adams-Huet, B.3    Cohen, J.B.4
  • 33
    • 77955248161 scopus 로고    scopus 로고
    • Relationships between obesity and the clinical severity of psoriasis in Taiwan
    • doi:10.1111/j.1468-3083.2010.03573.x
    • Huang YH, Yang LC, Hui RY, Chang YC, Yang YW, Yang CH, et al. Relationships between obesity and the clinical severity of psoriasis in Taiwan. J Eur Acad Dermatol Venereol. 2010;24(9): 1035-9. doi: 10. 1111/j. 1468-3083. 2010. 03573. x.
    • (2010) J Eur Acad Dermatol Venereol , vol.24 , Issue.9 , pp. 1035-1039
    • Huang, Y.H.1    Yang, L.C.2    Hui, R.Y.3    Chang, Y.C.4    Yang, Y.W.5    Yang, C.H.6
  • 34
    • 70350175881 scopus 로고    scopus 로고
    • Excessive body weight and smoking associates with a high risk of onset of plaque psoriasis
    • doi:10.2340/00015555-0711
    • Wolk K, Mallbris L, Larsson P, Rosenblad A, Vingard E, Stahle M. Excessive body weight and smoking associates with a high risk of onset of plaque psoriasis. Acta Derm Venereol. 2009;89(5): 492-7. doi: 10. 2340/00015555-0711.
    • (2009) Acta Derm Venereol , vol.89 , Issue.5 , pp. 492-497
    • Wolk, K.1    Mallbris, L.2    Larsson, P.3    Rosenblad, A.4    Vingard, E.5    Stahle, M.6
  • 35
    • 84873057794 scopus 로고    scopus 로고
    • Association between obesity measured by different parameters and severity of psoriasis
    • doi:10.1111/j.1365-4632.2011.05270.x
    • Duarte GV, Oliveira Mde F, Cardoso TM, Follador I, Silva TS, Cavalheiro CM, et al. Association between obesity measured by different parameters and severity of psoriasis. Int J Dermatol. 2013;52(2): 177-81. doi: 10. 1111/j. 1365-4632. 2011. 05270. x.
    • (2013) Int J Dermatol , vol.52 , Issue.2 , pp. 177-181
    • Duarte, G.V.1    Oliveira Mde, F.2    Cardoso, T.M.3    Follador, I.4    Silva, T.S.5    Cavalheiro, C.M.6
  • 36
    • 84884910431 scopus 로고    scopus 로고
    • Obesity, waist circumference, weight change and the risk of psoriasis in US women
    • doi:10.1111/jdv.12001
    • Kumar S, Han J, Li T, Qureshi AA. Obesity, waist circumference, weight change and the risk of psoriasis in US women. J Eur Acad Dermatol Venereol. 2012. doi: 10. 1111/jdv. 12001.
    • (2012) J Eur Acad Dermatol Venereol
    • Kumar, S.1    Han, J.2    Li, T.3    Qureshi, A.A.4
  • 37
    • 58149350282 scopus 로고    scopus 로고
    • Influence of body mass index, comorbidities and prior systemic therapies on the response of psoriasis to adalimumab: an exploratory analysis from the APHRODITE data
    • Cassano N, Galluccio A, De Simone C, Loconsole F, Massimino SD, Plumari A, et al. Influence of body mass index, comorbidities and prior systemic therapies on the response of psoriasis to adalimumab: an exploratory analysis from the APHRODITE data. J Biol Regul Homeost Agents. 2008;22(4): 233-7.
    • (2008) J Biol Regul Homeost Agents , vol.22 , Issue.4 , pp. 233-237
    • Cassano, N.1    Galluccio, A.2    De Simone, C.3    Loconsole, F.4    Massimino, S.D.5    Plumari, A.6
  • 38
    • 52049110303 scopus 로고    scopus 로고
    • Impact of body mass index and obesity on clinical response to systemic treatment for psoriasis. Evidence from the Psocare project
    • doi:10.1159/000156599
    • Naldi L, Addis A, Chimenti S, Giannetti A, Picardo M, Tomino C, et al. Impact of body mass index and obesity on clinical response to systemic treatment for psoriasis. Evidence from the Psocare project. Dermatology. 2008;217(4): 365-73. doi: 10. 1159/000156599.
    • (2008) Dermatology , vol.217 , Issue.4 , pp. 365-373
    • Naldi, L.1    Addis, A.2    Chimenti, S.3    Giannetti, A.4    Picardo, M.5    Tomino, C.6
  • 39
    • 55849143623 scopus 로고    scopus 로고
    • Weight loss improves the response of obese patients with moderate-to-severe chronic plaque psoriasis to low-dose cyclosporine therapy: a randomized, controlled, investigator-blinded clinical trial
    • Gisondi P, Del Giglio M, Di Francesco V, Zamboni M, Girolomoni G. Weight loss improves the response of obese patients with moderate-to-severe chronic plaque psoriasis to low-dose cyclosporine therapy: a randomized, controlled, investigator-blinded clinical trial. Am J Clin Nutr. 2008;88(5): 1242-7.
    • (2008) Am J Clin Nutr , vol.88 , Issue.5 , pp. 1242-1247
    • Gisondi, P.1    Del Giglio, M.2    Di Francesco, V.3    Zamboni, M.4    Girolomoni, G.5
  • 40
    • 78649400877 scopus 로고    scopus 로고
    • The role of drugs in the induction and/or exacerbation of psoriasis
    • doi:10.1111/j.1365-4632.2010.04570.x
    • Basavaraj KH, Ashok NM, Rashmi R, Praveen TK. The role of drugs in the induction and/or exacerbation of psoriasis. Int J Dermatol. 2010;49(12): 1351-61. doi: 10. 1111/j. 1365-4632. 2010. 04570. x.
    • (2010) Int J Dermatol , vol.49 , Issue.12 , pp. 1351-1361
    • Basavaraj, K.H.1    Ashok, N.M.2    Rashmi, R.3    Praveen, T.K.4
  • 41
    • 33745933352 scopus 로고    scopus 로고
    • The mechanism of lithium and beta-blocking agents in inducing and exacerbating psoriasis
    • O'Brien M, Koo J. The mechanism of lithium and beta-blocking agents in inducing and exacerbating psoriasis. J Drugs Dermatol. 2006;5(5): 426-32.
    • (2006) J Drugs Dermatol , vol.5 , Issue.5 , pp. 426-432
    • O'Brien, M.1    Koo, J.2
  • 42
    • 84880698542 scopus 로고    scopus 로고
    • Effect of weather and environmental factors on the clinical course of psoriasis
    • doi:10.1136/oemed-2013-101505
    • Balato N, Di Costanzo L, Patruno C, Patri A, Ayala F. Effect of weather and environmental factors on the clinical course of psoriasis. Occup Environ Med. 2013;70(8): 600. doi: 10. 1136/oemed-2013-101505.
    • (2013) Occup Environ Med , vol.70 , Issue.8 , pp. 600
    • Balato, N.1    Di Costanzo, L.2    Patruno, C.3    Patri, A.4    Ayala, F.5
  • 46
    • 0002639605 scopus 로고
    • Heredity and psoriasis. Study of a large family
    • Abele DC, Dobson RL, Graham JB. Heredity and psoriasis. Study of a large family. Arch Dermatol. 1963;88: 38-47.
    • (1963) Arch Dermatol , vol.88 , pp. 38-47
    • Abele, D.C.1    Dobson, R.L.2    Graham, J.B.3
  • 47
    • 0028238534 scopus 로고
    • An association between psoriasis and hereditary multiple exostoses. A clue for the mapping of a psoriasis susceptibility gene?
    • Rosbotham JL, Trembath RC, Glover M, Leigh I, Barker JN. An association between psoriasis and hereditary multiple exostoses. A clue for the mapping of a psoriasis susceptibility gene? Br J Dermatol. 1994;130(5): 671-4.
    • (1994) Br J Dermatol , vol.130 , Issue.5 , pp. 671-674
    • Rosbotham, J.L.1    Trembath, R.C.2    Glover, M.3    Leigh, I.4    Barker, J.N.5
  • 48
    • 0001862005 scopus 로고    scopus 로고
    • Epidemiology: natural history and genetics
    • J. H. M. Roenigk (Ed.), New York: Dekker
    • Farber EMNL. Epidemiology: natural history and genetics. In: Roenigk JHM, editor. Psoriasis. New York: Dekker; 1998. p. 107-57.
    • (1998) Psoriasis , pp. 107-157
    • Farber, E.M.N.L.1
  • 51
    • 0020051265 scopus 로고
    • Psoriasis in monozygotic twins: variations in expression in individuals with identical genetic constitution
    • Brandrup F, Holm N, Grunnet N, Henningsen K, Hansen HE. Psoriasis in monozygotic twins: variations in expression in individuals with identical genetic constitution. Acta Derm Venereol. 1982;62(3): 229-36.
    • (1982) Acta Derm Venereol , vol.62 , Issue.3 , pp. 229-236
    • Brandrup, F.1    Holm, N.2    Grunnet, N.3    Henningsen, K.4    Hansen, H.E.5
  • 53
    • 0016029730 scopus 로고
    • Natural history of psoriasis in 61 twin pairs
    • Farber EM, Nall ML, Watson W. Natural history of psoriasis in 61 twin pairs. Arch Dermatol. 1974;109(2): 207-11.
    • (1974) Arch Dermatol , vol.109 , Issue.2 , pp. 207-211
    • Farber, E.M.1    Nall, M.L.2    Watson, W.3
  • 54
    • 79959664445 scopus 로고    scopus 로고
    • HLA-C, CSTA and DS12346 susceptibility alleles confer over 100-fold increased risk of developing psoriasis: evidence of gene interaction
    • doi:10.1038/jhg.2011.33
    • Vasilopoulos Y, Sagoo GS, Cork MJ, Walters K, Tazi-Ahnini R. HLA-C, CSTA and DS12346 susceptibility alleles confer over 100-fold increased risk of developing psoriasis: evidence of gene interaction. J Hum Genet. 2011;56(6): 423-7. doi: 10. 1038/jhg. 2011. 33.
    • (2011) J Hum Genet , vol.56 , Issue.6 , pp. 423-427
    • Vasilopoulos, Y.1    Sagoo, G.S.2    Cork, M.J.3    Walters, K.4    Tazi-Ahnini, R.5
  • 55
    • 0033358609 scopus 로고    scopus 로고
    • Evidence for interaction between psoriasis-susceptibility loci on chromosomes 6p21 and 1q21
    • doi:10.1086/302653
    • Capon F, Semprini S, Dallapiccola B, Novelli G. Evidence for interaction between psoriasis-susceptibility loci on chromosomes 6p21 and 1q21. Am J Hum Genet. 1999;65(6): 1798-800. doi: 10. 1086/302653.
    • (1999) Am J Hum Genet , vol.65 , Issue.6 , pp. 1798-1800
    • Capon, F.1    Semprini, S.2    Dallapiccola, B.3    Novelli, G.4
  • 56
    • 0033795055 scopus 로고    scopus 로고
    • Genomewide scan in german families reveals evidence for a novel psoriasis-susceptibility locus on chromosome 19p13
    • doi:10.1086/303075
    • Lee YA, Ruschendorf F, Windemuth C, Schmitt-Egenolf M, Stadelmann A, Nurnberg G, et al. Genomewide scan in german families reveals evidence for a novel psoriasis-susceptibility locus on chromosome 19p13. Am J Hum Genet. 2000;67(4): 1020-4. doi: 10. 1086/303075.
    • (2000) Am J Hum Genet , vol.67 , Issue.4 , pp. 1020-1024
    • Lee, Y.A.1    Ruschendorf, F.2    Windemuth, C.3    Schmitt-Egenolf, M.4    Stadelmann, A.5    Nurnberg, G.6
  • 57
    • 0029819846 scopus 로고    scopus 로고
    • Evidence that a locus for familial psoriasis maps to chromosome 4q
    • doi:10.1038/ng1096-231
    • Matthews D, Fry L, Powles A, Weber J, McCarthy M, Fisher E, et al. Evidence that a locus for familial psoriasis maps to chromosome 4q. Nat Genet. 1996;14(2): 231-3. doi: 10. 1038/ng1096-231.
    • (1996) Nat Genet , vol.14 , Issue.2 , pp. 231-233
    • Matthews, D.1    Fry, L.2    Powles, A.3    Weber, J.4    McCarthy, M.5    Fisher, E.6
  • 58
    • 0343410359 scopus 로고    scopus 로고
    • Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan
    • Nair RP, Henseler T, Jenisch S, Stuart P, Bichakjian CK, Lenk W, et al. Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan. Hum Mol Genet. 1997;6(8): 1349-56.
    • (1997) Hum Mol Genet , vol.6 , Issue.8 , pp. 1349-1356
    • Nair, R.P.1    Henseler, T.2    Jenisch, S.3    Stuart, P.4    Bichakjian, C.K.5    Lenk, W.6
  • 59
    • 0033397121 scopus 로고    scopus 로고
    • A genome-wide search for genes predisposing to familial psoriasis by using a stratification approach
    • Samuelsson L, Enlund F, Torinsson A, Yhr M, Inerot A, Enerback C, et al. A genome-wide search for genes predisposing to familial psoriasis by using a stratification approach. Hum Genet. 1999;105(6): 523-9.
    • (1999) Hum Genet , vol.105 , Issue.6 , pp. 523-529
    • Samuelsson, L.1    Enlund, F.2    Torinsson, A.3    Yhr, M.4    Inerot, A.5    Enerback, C.6
  • 60
    • 8244228677 scopus 로고    scopus 로고
    • Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis
    • Trembath RC, Clough RL, Rosbotham JL, Jones AB, Camp RD, Frodsham A, et al. Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis. Hum Mol Genet. 1997;6(5): 813-20.
    • (1997) Hum Mol Genet , vol.6 , Issue.5 , pp. 813-820
    • Trembath, R.C.1    Clough, R.L.2    Rosbotham, J.L.3    Jones, A.B.4    Camp, R.D.5    Frodsham, A.6
  • 62
    • 34248549989 scopus 로고    scopus 로고
    • Confirmation of psoriasis susceptibility loci on chromosome 6p21 and 20p13 in French families
    • doi:10.1038/sj.jid.5700749
    • Lesueur F, Lefevre C, Has C, Guilloud-Bataille M, Oudot T, Mahe E, et al. Confirmation of psoriasis susceptibility loci on chromosome 6p21 and 20p13 in French families. J Invest Dermatol. 2007;127(6): 1403-9. doi: 10. 1038/sj. jid. 5700749.
    • (2007) J Invest Dermatol , vol.127 , Issue.6 , pp. 1403-1409
    • Lesueur, F.1    Lefevre, C.2    Has, C.3    Guilloud-Bataille, M.4    Oudot, T.5    Mahe, E.6
  • 63
    • 84857560127 scopus 로고    scopus 로고
    • Current understanding of human geneBcs and geneBc analysis of psoriasis
    • doi: 10. 1111/j. 1346-8138. 2012. 01504. x
    • Oka A, Mabuchi T, Ozawa A, Inoko H. Current understanding of human geneBcs and geneBc analysis of psoriasis. J Dermatol. 2012;39(3): 231-41. doi: 10. 1111/j. 1346-8138. 2012. 01504. x.
    • (2012) J Dermatol. , vol.39 , Issue.3 , pp. 231-241
    • Oka, A.1    Mabuchi, T.2    Ozawa, A.3    Inoko, H.4
  • 64
    • 36049005539 scopus 로고    scopus 로고
    • The genetic basis of psoriasis
    • doi:10.1016/j.clindermatol.2007.08.010
    • Valdimarsson H. The genetic basis of psoriasis. Clin Dermatol. 2007;25(6): 563-7. doi: 10. 1016/j. clindermatol. 2007. 08. 010.
    • (2007) Clin Dermatol , vol.25 , Issue.6 , pp. 563-567
    • Valdimarsson, H.1
  • 65
    • 33646049742 scopus 로고    scopus 로고
    • Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene
    • doi:10.1086/503821
    • Nair RP, Stuart PE, Nistor I, Hiremagalore R, Chia NV, Jenisch S, et al. Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene. Am J Hum Genet. 2006;78(5): 827-51. doi: 10. 1086/503821.
    • (2006) Am J Hum Genet , vol.78 , Issue.5 , pp. 827-851
    • Nair, R.P.1    Stuart, P.E.2    Nistor, I.3    Hiremagalore, R.4    Chia, N.V.5    Jenisch, S.6
  • 66
    • 0032865897 scopus 로고    scopus 로고
    • HLA-Cw6 and the genetic predisposition to psoriasis: a meta-analysis of published serologic studies
    • doi:10.1046/j.1523-1747.1999.00724.x
    • Mallon E, Newson R, Bunker CB. HLA-Cw6 and the genetic predisposition to psoriasis: a meta-analysis of published serologic studies. J Invest Dermatol. 1999;113(4): 693-5. doi: 10. 1046/j. 1523-1747. 1999. 00724. x.
    • (1999) J Invest Dermatol , vol.113 , Issue.4 , pp. 693-695
    • Mallon, E.1    Newson, R.2    Bunker, C.B.3
  • 67
    • 0015504339 scopus 로고
    • Histocompatibility (HL-A) antigens associated with psoriasis
    • doi:10.1056/NEJM197210122871503
    • Russell TJ, Schultes LM, Kuban DJ. Histocompatibility (HL-A) antigens associated with psoriasis. N Engl J Med. 1972;287(15): 738-40. doi: 10. 1056/NEJM197210122871503.
    • (1972) N Engl J Med , vol.287 , Issue.15 , pp. 738-740
    • Russell, T.J.1    Schultes, L.M.2    Kuban, D.J.3
  • 68
    • 41949105512 scopus 로고    scopus 로고
    • Fine mapping of the psoriasis susceptibility locus PSORS1 supports HLA-C as the susceptibility gene in the Han Chinese population
    • doi:10.1371/journal.pgen.1000038
    • Fan X, Yang S, Huang W, Wang ZM, Sun LD, Liang YH, et al. Fine mapping of the psoriasis susceptibility locus PSORS1 supports HLA-C as the susceptibility gene in the Han Chinese population. PLoS Genet. 2008;4(3): e1000038. doi: 10. 1371/journal. pgen. 1000038.
    • (2008) PLoS Genet , vol.4 , Issue.3
    • Fan, X.1    Yang, S.2    Huang, W.3    Wang, Z.M.4    Sun, L.D.5    Liang, Y.H.6
  • 69
    • 84859176868 scopus 로고    scopus 로고
    • Psoriasis patients are enriched for genetic variants that protect against HIV-1 disease
    • doi:10.1371/journal.pgen.1002514
    • Chen H, Hayashi G, Lai OY, Dilthey A, Kuebler PJ, Wong TV, et al. Psoriasis patients are enriched for genetic variants that protect against HIV-1 disease. PLoS Genet. 2012;8(2): e1002514. doi: 10. 1371/journal. pgen. 1002514.
    • (2012) PLoS Genet , vol.8 , Issue.2
    • Chen, H.1    Hayashi, G.2    Lai, O.Y.3    Dilthey, A.4    Kuebler, P.J.5    Wong, T.V.6
  • 70
    • 79959503826 scopus 로고    scopus 로고
    • The InternaBonal HapMap Project
    • InternaBonal HapMap ConsorBum
    • InternaBonal HapMap ConsorBum. The InternaBonal HapMap Project. Nature. 2003;426(6968): 789-96.
    • (2003) Nature. , vol.426 , Issue.6968 , pp. 789-796
  • 71
    • 33846608131 scopus 로고    scopus 로고
    • A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes
    • doi:10.1086/511051
    • Cargill M, Schrodi SJ, Chang M, Garcia VE, Brandon R, Callis KP, et al. A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet. 2007;80(2): 273-90. doi: 10. 1086/511051.
    • (2007) Am J Hum Genet , vol.80 , Issue.2 , pp. 273-290
    • Cargill, M.1    Schrodi, S.J.2    Chang, M.3    Garcia, V.E.4    Brandon, R.5    Callis, K.P.6
  • 72
    • 78049350350 scopus 로고    scopus 로고
    • Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis
    • doi:10.1038/ng.688
    • Huffmeier U, Uebe S, Ekici AB, Bowes J, Giardina E, Korendowych E, et al. Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis. Nat Genet. 2010;42(11): 996-9. doi: 10. 1038/ng. 688.
    • (2010) Nat Genet , vol.42 , Issue.11 , pp. 996-999
    • Huffmeier, U.1    Uebe, S.2    Ekici, A.B.3    Bowes, J.4    Giardina, E.5    Korendowych, E.6
  • 74
    • 84860770362 scopus 로고    scopus 로고
    • PSORS2 is due to mutations in CARD14
    • The study reports rare, highly penetrant mutations in caspase recruitment domain 14 (CARD14) that seggregated with psoriasis. The study highlights the role of rare variants in psoriasis, doi:10.1016/j.ajhg.2012.03.012
    • Jordan CT, Cao L, Roberson ED, Pierson KC, Yang CF, Joyce CE, et al. PSORS2 is due to mutations in CARD14. Am J Hum Genet. 2012;90(5): 784-95. doi: 10. 1016/j. ajhg. 2012. 03. 012. The study reports rare, highly penetrant mutations in caspase recruitment domain 14 (CARD14) that seggregated with psoriasis. The study highlights the role of rare variants in psoriasis.
    • (2012) Am J Hum Genet , vol.90 , Issue.5 , pp. 784-795
    • Jordan, C.T.1    Cao, L.2    Roberson, E.D.3    Pierson, K.C.4    Yang, C.F.5    Joyce, C.E.6
  • 75
    • 80052744921 scopus 로고    scopus 로고
    • Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis
    • doi:10.1016/j.ajhg.2011.07.022
    • Onoufriadis A, Simpson MA, Pink AE, Di Meglio P, Smith CH, Pullabhatla V, et al. Mutations in IL36RN/IL1F5 are associated with the severe episodic inflammatory skin disease known as generalized pustular psoriasis. Am J Hum Genet. 2011;89(3): 432-7. doi: 10. 1016/j. ajhg. 2011. 07. 022.
    • (2011) Am J Hum Genet , vol.89 , Issue.3 , pp. 432-437
    • Onoufriadis, A.1    Simpson, M.A.2    Pink, A.E.3    Di Meglio, P.4    Smith, C.H.5    Pullabhatla, V.6
  • 76
    • 78149470326 scopus 로고    scopus 로고
    • Carriers of rare missense variants in IFIH1 are protected from psoriasis
    • doi:10.1038/jid.2010.214
    • Li Y, Liao W, Cargill M, Chang M, Matsunami N, Feng BJ, et al. Carriers of rare missense variants in IFIH1 are protected from psoriasis. J Invest Dermatol. 2010;130(12): 2768-72. doi: 10. 1038/jid. 2010. 214.
    • (2010) J Invest Dermatol , vol.130 , Issue.12 , pp. 2768-2772
    • Li, Y.1    Liao, W.2    Cargill, M.3    Chang, M.4    Matsunami, N.5    Feng, B.J.6
  • 77
    • 0030749533 scopus 로고    scopus 로고
    • Evidence that HLA-Cw6 determines early onset of psoriasis, obtained using sequence-specific primers (PCR-SSP)
    • Enerback C, Martinsson T, Inerot A, Wahlstrom J, Enlund F, Yhr M, et al. Evidence that HLA-Cw6 determines early onset of psoriasis, obtained using sequence-specific primers (PCR-SSP). Acta Derm Venereol. 1997;77(4): 273-6.
    • (1997) Acta Derm Venereol , vol.77 , Issue.4 , pp. 273-276
    • Enerback, C.1    Martinsson, T.2    Inerot, A.3    Wahlstrom, J.4    Enlund, F.5    Yhr, M.6
  • 78
    • 0037326130 scopus 로고    scopus 로고
    • Psoriasis patients who are homozygous for the HLA-Cw*0602 allele have a 2.5-fold increased risk of developing psoriasis compared with Cw6 heterozygotes
    • Gudjonsson JE, Karason A, Antonsdottir A, Runarsdottir EH, Hauksson VB, Upmanyu R, et al. Psoriasis patients who are homozygous for the HLA-Cw*0602 allele have a 2. 5-fold increased risk of developing psoriasis compared with Cw6 heterozygotes. Br J Dermatol. 2003;148(2): 233-5.
    • (2003) Br J Dermatol , vol.148 , Issue.2 , pp. 233-235
    • Gudjonsson, J.E.1    Karason, A.2    Antonsdottir, A.3    Runarsdottir, E.H.4    Hauksson, V.B.5    Upmanyu, R.6
  • 79
    • 0036181642 scopus 로고    scopus 로고
    • HLA-Cw6-positive and HLA-Cw6-negative patients with Psoriasis vulgaris have distinct clinical features
    • doi:10.1046/j.0022-202x.2001.01656.x
    • Gudjonsson JE, Karason A, Antonsdottir AA, Runarsdottir EH, Gulcher JR, Stefansson K, et al. HLA-Cw6-positive and HLA-Cw6-negative patients with Psoriasis vulgaris have distinct clinical features. J Invest Dermatol. 2002;118(2): 362-5. doi: 10. 1046/j. 0022-202x. 2001. 01656. x.
    • (2002) J Invest Dermatol , vol.118 , Issue.2 , pp. 362-365
    • Gudjonsson, J.E.1    Karason, A.2    Antonsdottir, A.A.3    Runarsdottir, E.H.4    Gulcher, J.R.5    Stefansson, K.6
  • 81
    • 84881573482 scopus 로고    scopus 로고
    • Genetic associations of psoriasis in a Pakistani population
    • doi:10.1111/bjd.12313
    • Shaiq PA, Stuart PE, Latif A, Schmotzer C, Kazmi AH, Khan MS, et al. Genetic associations of psoriasis in a Pakistani population. Br J Dermatol. 2013;169(2): 406-11. doi: 10. 1111/bjd. 12313.
    • (2013) Br J Dermatol , vol.169 , Issue.2 , pp. 406-411
    • Shaiq, P.A.1    Stuart, P.E.2    Latif, A.3    Schmotzer, C.4    Kazmi, A.H.5    Khan, M.S.6
  • 82
    • 34547774225 scopus 로고    scopus 로고
    • Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis
    • doi:10.1007/s00439-007-0397-0
    • Capon F, Di Meglio P, Szaub J, Prescott NJ, Dunster C, Baumber L, et al. Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis. Hum Genet. 2007;122(2): 201-6. doi: 10. 1007/s00439-007-0397-0.
    • (2007) Hum Genet , vol.122 , Issue.2 , pp. 201-206
    • Capon, F.1    Di Meglio, P.2    Szaub, J.3    Prescott, N.J.4    Dunster, C.5    Baumber, L.6
  • 83
    • 0347285359 scopus 로고    scopus 로고
    • Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris
    • doi:10.1084/jem.20030451
    • Lee E, Trepicchio WL, Oestreicher JL, Pittman D, Wang F, Chamian F, et al. Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris. J Exp Med. 2004;199(1): 125-30. doi: 10. 1084/jem. 20030451.
    • (2004) J Exp Med , vol.199 , Issue.1 , pp. 125-130
    • Lee, E.1    Trepicchio, W.L.2    Oestreicher, J.L.3    Pittman, D.4    Wang, F.5    Chamian, F.6
  • 84
    • 31144441631 scopus 로고    scopus 로고
    • In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin
    • Piskin G, Sylva-Steenland RM, Bos JD, Teunissen MB. In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin. J Immunol. 2006;176(3): 1908-15.
    • (2006) J Immunol , vol.176 , Issue.3 , pp. 1908-1915
    • Piskin, G.1    Sylva-Steenland, R.M.2    Bos, J.D.3    Teunissen, M.B.4
  • 85
    • 10344243973 scopus 로고    scopus 로고
    • Clinical improvement in chronic plaque-type psoriasis lesions after narrow-band UVB therapy is accompanied by a decrease in the expression of IFN-gamma inducers - IL-12, IL-18 and IL-23
    • doi:10.1111/j.0906-6705.2004.00246.x
    • Piskin G, Tursen U, Sylva-Steenland RM, Bos JD, Teunissen MB. Clinical improvement in chronic plaque-type psoriasis lesions after narrow-band UVB therapy is accompanied by a decrease in the expression of IFN-gamma inducers - IL-12, IL-18 and IL-23. Exp Dermatol. 2004;13(12): 764-72. doi: 10. 1111/j. 0906-6705. 2004. 00246. x.
    • (2004) Exp Dermatol , vol.13 , Issue.12 , pp. 764-772
    • Piskin, G.1    Tursen, U.2    Sylva-Steenland, R.M.3    Bos, J.D.4    Teunissen, M.B.5
  • 86
    • 39649108216 scopus 로고    scopus 로고
    • Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: results of a randomized, placebo-controlled, phase 2 trial
    • doi:10.1001/archdermatol.2007.63
    • Kimball AB, Gordon KB, Langley RG, Menter A, Chartash EK, Valdes J. Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: results of a randomized, placebo-controlled, phase 2 trial. Arch Dermatol. 2008;144(2): 200-7. doi: 10. 1001/archdermatol. 2007. 63.
    • (2008) Arch Dermatol , vol.144 , Issue.2 , pp. 200-207
    • Kimball, A.B.1    Gordon, K.B.2    Langley, R.G.3    Menter, A.4    Chartash, E.K.5    Valdes, J.6
  • 87
    • 33846889522 scopus 로고    scopus 로고
    • A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis
    • doi:10.1056/NEJMoa062382
    • Krueger GG, Langley RG, Leonardi C, Yeilding N, Guzzo C, Wang Y, et al. A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis. N Engl J Med. 2007;356(6): 580-92. doi: 10. 1056/NEJMoa062382.
    • (2007) N Engl J Med , vol.356 , Issue.6 , pp. 580-592
    • Krueger, G.G.1    Langley, R.G.2    Leonardi, C.3    Yeilding, N.4    Guzzo, C.5    Wang, Y.6
  • 88
    • 80855163601 scopus 로고    scopus 로고
    • Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: a meta-analysis
    • doi:10.3109/09546634.2010.487890
    • Tan JY, Li S, Yang K, Ma B, Chen W, Zha C, et al. Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: a meta-analysis. J Dermatol Treat. 2011;22(6): 323-36. doi: 10. 3109/09546634. 2010. 487890.
    • (2011) J Dermatol Treat , vol.22 , Issue.6 , pp. 323-336
    • Tan, J.Y.1    Li, S.2    Yang, K.3    Ma, B.4    Chen, W.5    Zha, C.6
  • 89
    • 79952066088 scopus 로고    scopus 로고
    • The IL23R R381Q gene variant protects against immunemediated diseases by impairing IL-23-induced Th17 effector response in humans
    • doi: 10. 1371/journal. pone. 0017160
    • Di Meglio P, Di Cesare A, Laggner U, Chu CC, Napolitano L, Villanova F et al. The IL23R R381Q gene variant protects against immunemediated diseases by impairing IL-23-induced Th17 effector response in humans. PLoS One. 2011;6(2): e17160. doi: 10. 1371/journal. pone. 0017160.
    • (2011) PLoS One. , vol.6 , Issue.2
    • Di Meglio, P.1    Di Cesare, A.2    Laggner, U.3    Chu, C.C.4    Napolitano, L.5    Villanova, F.6
  • 90
    • 84884287706 scopus 로고    scopus 로고
    • The IL23R A/Gln381 Allele Promotes IL-23 Unresponsiveness in Human Memory T-Helper 17 Cells and Impairs Th17 Responses in Psoriasis Patients
    • doi:10.1038/jid.2013.170
    • Di Meglio P, Villanova F, Napolitano L, Tosi I, Terranova Barberio M, Mak RK, et al. The IL23R A/Gln381 Allele Promotes IL-23 Unresponsiveness in Human Memory T-Helper 17 Cells and Impairs Th17 Responses in Psoriasis Patients. J Invest Dermatol. 2013;133(10): 2381-9. doi: 10. 1038/jid. 2013. 170.
    • (2013) J Invest Dermatol , vol.133 , Issue.10 , pp. 2381-2389
    • Di Meglio, P.1    Villanova, F.2    Napolitano, L.3    Tosi, I.4    Terranova Barberio, M.5    Mak, R.K.6
  • 91
    • 34247523141 scopus 로고    scopus 로고
    • Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation
    • doi:10.1146/annurev.immunol.22.012703.104758
    • Kastelein RA, Hunter CA, Cua DJ. Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation. Ann Rev Immunol. 2007;25: 221-42. doi: 10. 1146/annurev. immunol. 22. 012703. 104758.
    • (2007) Ann Rev Immunol , vol.25 , pp. 221-242
    • Kastelein, R.A.1    Hunter, C.A.2    Cua, D.J.3
  • 92
    • 33846966636 scopus 로고    scopus 로고
    • A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage
    • doi:10.1038/nm1551
    • Steinman L. A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nat Med. 2007;13(2): 139-45. doi: 10. 1038/nm1551.
    • (2007) Nat Med , vol.13 , Issue.2 , pp. 139-145
    • Steinman, L.1
  • 93
    • 84870466814 scopus 로고    scopus 로고
    • Targeting the Th17 pathway in psoriasis
    • doi:10.1189/jlb.0212101
    • Elloso MM, Gomez-Angelats M, Fourie AM. Targeting the Th17 pathway in psoriasis. J Leukoc Biol. 2012;92(6): 1187-97. doi: 10. 1189/jlb. 0212101.
    • (2012) J Leukoc Biol , vol.92 , Issue.6 , pp. 1187-1197
    • Elloso, M.M.1    Gomez-Angelats, M.2    Fourie, A.M.3
  • 94
    • 84872275425 scopus 로고    scopus 로고
    • The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings
    • Review of emerging role of IL-17 cytokine family in psoriasis. The review provides a comprehensive overview of the clinical and animal studies on the role of IL-17 in psoriasis. The review also presents a model of psoriasis pathogenesis, in which IL-17 plays a key role, doi:10.1038/jid.2012.194
    • Martin DA, Towne JE, Kricorian G, Klekotka P, Gudjonsson JE, Krueger JG, et al. The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings. J Invest Dermatol. 2013;133(1): 17-26. doi: 10. 1038/jid. 2012. 194. Review of emerging role of IL-17 cytokine family in psoriasis. The review provides a comprehensive overview of the clinical and animal studies on the role of IL-17 in psoriasis. The review also presents a model of psoriasis pathogenesis, in which IL-17 plays a key role.
    • (2013) J Invest Dermatol , vol.133 , Issue.1 , pp. 17-26
    • Martin, D.A.1    Towne, J.E.2    Kricorian, G.3    Klekotka, P.4    Gudjonsson, J.E.5    Krueger, J.G.6
  • 95
    • 77951091571 scopus 로고    scopus 로고
    • Circulating Th17, Th22, and Th1 cells are increased in psoriasis
    • doi:10.1038/jid.2009.399
    • Kagami S, Rizzo HL, Lee JJ, Koguchi Y, Blauvelt A. Circulating Th17, Th22, and Th1 cells are increased in psoriasis. J Invest Dermatol. 2010;130(5): 1373-83. doi: 10. 1038/jid. 2009. 399.
    • (2010) J Invest Dermatol , vol.130 , Issue.5 , pp. 1373-1383
    • Kagami, S.1    Rizzo, H.L.2    Lee, J.J.3    Koguchi, Y.4    Blauvelt, A.5
  • 96
    • 79959584686 scopus 로고    scopus 로고
    • Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis
    • doi:10.4049/jimmunol.1100123
    • Lin AM, Rubin CJ, Khandpur R, Wang JY, Riblett M, Yalavarthi S, et al. Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis. J Immunol. 2011;187(1): 490-500. doi: 10. 4049/jimmunol. 1100123.
    • (2011) J Immunol , vol.187 , Issue.1 , pp. 490-500
    • Lin, A.M.1    Rubin, C.J.2    Khandpur, R.3    Wang, J.Y.4    Riblett, M.5    Yalavarthi, S.6
  • 97
    • 42149087160 scopus 로고    scopus 로고
    • Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells
    • doi:10.1038/sj.jid.5701213
    • Lowes MA, Kikuchi T, Fuentes-Duculan J, Cardinale I, Zaba LC, Haider AS, et al. Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells. J Invest Dermatol. 2008;128(5): 1207-11. doi: 10. 1038/sj. jid. 5701213.
    • (2008) J Invest Dermatol , vol.128 , Issue.5 , pp. 1207-1211
    • Lowes, M.A.1    Kikuchi, T.2    Fuentes-Duculan, J.3    Cardinale, I.4    Zaba, L.C.5    Haider, A.S.6
  • 98
    • 58349105187 scopus 로고    scopus 로고
    • Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin
    • doi:10.1111/j.1365-2133.2008.08902.x
    • Johansen C, Usher PA, Kjellerup RB, Lundsgaard D, Iversen L, Kragballe K. Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin. Br J Dermatol. 2009;160(2): 319-24. doi: 10. 1111/j. 1365-2133. 2008. 08902. x.
    • (2009) Br J Dermatol , vol.160 , Issue.2 , pp. 319-324
    • Johansen, C.1    Usher, P.A.2    Kjellerup, R.B.3    Lundsgaard, D.4    Iversen, L.5    Kragballe, K.6
  • 99
    • 79955045064 scopus 로고    scopus 로고
    • Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesions in a mouse model
    • doi:10.4049/jimmunol.1000148
    • Nakajima K, Kanda T, Takaishi M, Shiga T, Miyoshi K, Nakajima H, et al. Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesions in a mouse model. J Immunol. 2011;186(7): 4481-9. doi: 10. 4049/jimmunol. 1000148.
    • (2011) J Immunol , vol.186 , Issue.7 , pp. 4481-4489
    • Nakajima, K.1    Kanda, T.2    Takaishi, M.3    Shiga, T.4    Miyoshi, K.5    Nakajima, H.6
  • 100
    • 0032729645 scopus 로고    scopus 로고
    • The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients
    • doi:10.1046/j.1523-1747.1999.00749.x
    • Austin LM, Ozawa M, Kikuchi T, Walters IB, Krueger JG. The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients. J Invest Dermatol. 1999;113(5): 752-9. doi: 10. 1046/j. 1523-1747. 1999. 00749. x.
    • (1999) J Invest Dermatol , vol.113 , Issue.5 , pp. 752-759
    • Austin, L.M.1    Ozawa, M.2    Kikuchi, T.3    Walters, I.B.4    Krueger, J.G.5
  • 101
    • 0020595264 scopus 로고
    • Immunocompetent cells in psoriasis. In situ immunophenotyping by monoclonal antibodies
    • Bos JD, Hulsebosch HJ, Krieg SR, Bakker PM, Cormane RH. Immunocompetent cells in psoriasis. In situ immunophenotyping by monoclonal antibodies. Arch Dermatol Res. 1983;275(3): 181-9.
    • (1983) Arch Dermatol Res , vol.275 , Issue.3 , pp. 181-189
    • Bos, J.D.1    Hulsebosch, H.J.2    Krieg, S.R.3    Bakker, P.M.4    Cormane, R.H.5
  • 102
    • 0028245467 scopus 로고
    • Characterization of dermal dendritic cells in psoriasis. Autostimulation of T lymphocytes and induction of Th1 type cytokines
    • Nestle FO, Turka LA, Nickoloff BJ. Characterization of dermal dendritic cells in psoriasis. Autostimulation of T lymphocytes and induction of Th1 type cytokines. J Clin Invest. 1994;94(1): 202-9.
    • (1994) J Clin Invest , vol.94 , Issue.1 , pp. 202-209
    • Nestle, F.O.1    Turka, L.A.2    Nickoloff, B.J.3
  • 103
    • 0032698980 scopus 로고    scopus 로고
    • Skin innate immune system in psoriasis: friend or foe?
    • doi:10.1172/JCI8633
    • Nickoloff BJ. Skin innate immune system in psoriasis: friend or foe? J Clin Invest. 1999;104(9): 1161-4. doi: 10. 1172/JCI8633.
    • (1999) J Clin Invest , vol.104 , Issue.9 , pp. 1161-1164
    • Nickoloff, B.J.1
  • 105
    • 0025862110 scopus 로고
    • Chimaeric CD4 monoclonal antibody in treatment of generalised pustular psoriasis
    • Prinz J, Braun-Falco O, Meurer M, Daddona P, Reiter C, Rieber P, et al. Chimaeric CD4 monoclonal antibody in treatment of generalised pustular psoriasis. Lancet. 1991;338(8762): 320-1.
    • (1991) Lancet , vol.338 , Issue.8762 , pp. 320-321
    • Prinz, J.1    Braun-Falco, O.2    Meurer, M.3    Daddona, P.4    Reiter, C.5    Rieber, P.6
  • 106
    • 84860389384 scopus 로고    scopus 로고
    • Innate immunity in the pathogenesis of psoriasis
    • This review provides evidence of the role of innate immune system in pathogenesis of psoriasis, doi:10.1007/s00403-011-1169-1
    • Sweeney CM, Tobin AM, Kirby B. Innate immunity in the pathogenesis of psoriasis. Arch Dermatol Res. 2011;303(10): 691-705. doi: 10. 1007/s00403-011-1169-1. This review provides evidence of the role of innate immune system in pathogenesis of psoriasis.
    • (2011) Arch Dermatol Res , vol.303 , Issue.10 , pp. 691-705
    • Sweeney, C.M.1    Tobin, A.M.2    Kirby, B.3
  • 107
    • 0034292333 scopus 로고    scopus 로고
    • Overexpression of CD1d by keratinocytes in psoriasis and CD1d-dependent IFN-gamma production by NK-T cells
    • Bonish B, Jullien D, Dutronc Y, Huang BB, Modlin R, Spada FM, et al. Overexpression of CD1d by keratinocytes in psoriasis and CD1d-dependent IFN-gamma production by NK-T cells. J Immunol. 2000;165(7): 4076-85.
    • (2000) J Immunol , vol.165 , Issue.7 , pp. 4076-4085
    • Bonish, B.1    Jullien, D.2    Dutronc, Y.3    Huang, B.B.4    Modlin, R.5    Spada, F.M.6
  • 111
    • 76749141832 scopus 로고    scopus 로고
    • Progress in understanding the immunopathogenesis of psoriasis
    • Mak RK, Hundhausen C, Nestle FO. Progress in understanding the immunopathogenesis of psoriasis. Actas Derm Sifiliograficas. 2009;100 Suppl 2: 2-13.
    • (2009) Actas Derm Sifiliograficas , vol.100 , Issue.SUPPL. 2 , pp. 2-13
    • Mak, R.K.1    Hundhausen, C.2    Nestle, F.O.3
  • 112
    • 84857603197 scopus 로고    scopus 로고
    • The concept of psoriasis as a systemic inflammation: implications for disease management
    • doi:10.1111/j.1468-3083.2011.04410.x
    • Reich K. The concept of psoriasis as a systemic inflammation: implications for disease management. J Eur Acad Dermatol Venereol. 2012;26 Suppl 2: 3-11. doi: 10. 1111/j. 1468-3083. 2011. 04410. x.
    • (2012) J Eur Acad Dermatol Venereol , vol.26 , Issue.SUPPL. 2 , pp. 3-11
    • Reich, K.1
  • 113
    • 34948862264 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide
    • doi:10.1038/nature06116
    • Lande R, Gregorio J, Facchinetti V, Chatterjee B, Wang YH, Homey B, et al. Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature. 2007;449(7162): 564-9. doi: 10. 1038/nature06116.
    • (2007) Nature , vol.449 , Issue.7162 , pp. 564-569
    • Lande, R.1    Gregorio, J.2    Facchinetti, V.3    Chatterjee, B.4    Wang, Y.H.5    Homey, B.6
  • 114
    • 69549135324 scopus 로고    scopus 로고
    • Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8
    • doi:10.1084/jem.20090480
    • Ganguly D, Chamilos G, Lande R, Gregorio J, Meller S, Facchinetti V, et al. Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8. J Exp Med. 2009;206(9): 1983-94. doi: 10. 1084/jem. 20090480.
    • (2009) J Exp Med , vol.206 , Issue.9 , pp. 1983-1994
    • Ganguly, D.1    Chamilos, G.2    Lande, R.3    Gregorio, J.4    Meller, S.5    Facchinetti, V.6
  • 116
    • 29144466801 scopus 로고    scopus 로고
    • Prevalence and treatment of psoriasis in the United Kingdom: a population-based study
    • doi:10.1001/archderm.141.12.1537
    • Gelfand JM, Weinstein R, Porter SB, Neimann AL, Berlin JA, Margolis DJ. Prevalence and treatment of psoriasis in the United Kingdom: a population-based study. Arch Dermatol. 2005;141(12): 1537-41. doi: 10. 1001/archderm. 141. 12. 1537.
    • (2005) Arch Dermatol , vol.141 , Issue.12 , pp. 1537-1541
    • Gelfand, J.M.1    Weinstein, R.2    Porter, S.B.3    Neimann, A.L.4    Berlin, J.A.5    Margolis, D.J.6
  • 117
    • 84872620069 scopus 로고    scopus 로고
    • Global epidemiology of psoriasis: a systematic review of incidence and prevalence
    • Identification, Management of P, doi:10.1038/jid.2012.339
    • Parisi R, Symmons DP, Griffiths CE, Ashcroft DM, Identification, Management of P, et al. Global epidemiology of psoriasis: a systematic review of incidence and prevalence. J Invest Dermatol. 2013;133(2): 377-85. doi: 10. 1038/jid. 2012. 339.
    • (2013) J Invest Dermatol , vol.133 , Issue.2 , pp. 377-385
    • Parisi, R.1    Symmons, D.P.2    Griffiths, C.E.3    Ashcroft, D.M.4
  • 120
    • 79960899377 scopus 로고    scopus 로고
    • Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility
    • doi:10.1038/ng.873
    • Evans DM, Spencer CC, Pointon JJ, Su Z, Harvey D, Kochan G, et al. Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat Genet. 2011;43(8): 761-7. doi: 10. 1038/ng. 873.
    • (2011) Nat Genet , vol.43 , Issue.8 , pp. 761-767
    • Evans, D.M.1    Spencer, C.C.2    Pointon, J.J.3    Su, Z.4    Harvey, D.5    Kochan, G.6
  • 121
    • 67649876123 scopus 로고    scopus 로고
    • Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
    • doi:10.1038/ng.401
    • De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT, et al. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet. 2009;41(7): 776-82. doi: 10. 1038/ng. 401.
    • (2009) Nat Genet , vol.41 , Issue.7 , pp. 776-782
    • De Jager, P.L.1    Jia, X.2    Wang, J.3    de Bakker, P.I.4    Ottoboni, L.5    Aggarwal, N.T.6
  • 122
    • 84255194782 scopus 로고    scopus 로고
    • Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci
    • doi:10.1002/ana.22609
    • Patsopoulos NA, Esposito F, Reischl J, Lehr S, Bauer D, Heubach J, et al. Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol. 2011;70(6): 897-912. doi: 10. 1002/ana. 22609.
    • (2011) Ann Neurol , vol.70 , Issue.6 , pp. 897-912
    • Patsopoulos, N.A.1    Esposito, F.2    Reischl, J.3    Lehr, S.4    Bauer, D.5    Heubach, J.6
  • 123
    • 84868336049 scopus 로고    scopus 로고
    • Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
    • doi:10.1038/nature11582
    • Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature. 2012;491(7422): 119-24. doi: 10. 1038/nature11582.
    • (2012) Nature , vol.491 , Issue.7422 , pp. 119-124
    • Jostins, L.1    Ripke, S.2    Weersma, R.K.3    Duerr, R.H.4    McGovern, D.P.5    Hui, K.Y.6
  • 124
    • 79952465426 scopus 로고    scopus 로고
    • HLA-C locus and genetic susceptibility to psoriatic arthritis in Romanian population
    • doi:10.1111/j.1399-0039.2010.01624.x
    • Popa OM, Popa L, Dutescu MI, Bojinca M, Bojinca V, Ciofu C, et al. HLA-C locus and genetic susceptibility to psoriatic arthritis in Romanian population. Tissue Antigens. 2011;77(4): 325-8. doi: 10. 1111/j. 1399-0039. 2010. 01624. x.
    • (2011) Tissue Antigens , vol.77 , Issue.4 , pp. 325-328
    • Popa, O.M.1    Popa, L.2    Dutescu, M.I.3    Bojinca, M.4    Bojinca, V.5    Ciofu, C.6
  • 125
    • 73349115848 scopus 로고    scopus 로고
    • The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes
    • Wallace C, Smyth DJ, Maisuria-Armer M, Walker NM, Todd JA, Clayton DG. The imprinted DLK1-MEG3 gene region on chromosome 14q32. 2 alters susceptibility to type 1 diabetes. Nat Genet. 2010;42(1): 68-71.
    • (2010) Nat Genet , vol.42 , Issue.1 , pp. 68-71
    • Wallace, C.1    Smyth, D.J.2    Maisuria-Armer, M.3    Walker, N.M.4    Todd, J.A.5    Clayton, D.G.6
  • 126
    • 80052311755 scopus 로고    scopus 로고
    • Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases
    • doi:10.1371/journal.pgen.1002216
    • Plagnol V, Howson JM, Smyth DJ, Walker N, Hafler JP, Wallace C, et al. Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. PLoS Genet. 2011;7(8): e1002216. doi: 10. 1371/journal. pgen. 1002216.
    • (2011) PLoS Genet , vol.7 , Issue.8
    • Plagnol, V.1    Howson, J.M.2    Smyth, D.J.3    Walker, N.4    Hafler, J.P.5    Wallace, C.6
  • 127
    • 78649489009 scopus 로고    scopus 로고
    • Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
    • doi:10.1038/ng.717
    • Franke A, McGovern DP, Barrett JC, Wang K, Radford-Smith GL, Ahmad T, et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet. 2010;42(12): 1118-25. doi: 10. 1038/ng. 717.
    • (2010) Nat Genet , vol.42 , Issue.12 , pp. 1118-1125
    • Franke, A.1    McGovern, D.P.2    Barrett, J.C.3    Wang, K.4    Radford-Smith, G.L.5    Ahmad, T.6
  • 128
    • 84872328824 scopus 로고    scopus 로고
    • Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians
    • doi:10.1016/j.ajhg.2012.11.018
    • Yang W, Tang H, Zhang Y, Tang X, Zhang J, Sun L, et al. Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. Am J Hum Genet. 2013;92(1): 41-51. doi: 10. 1016/j. ajhg. 2012. 11. 018.
    • (2013) Am J Hum Genet , vol.92 , Issue.1 , pp. 41-51
    • Yang, W.1    Tang, H.2    Zhang, Y.3    Tang, X.4    Zhang, J.5    Sun, L.6
  • 129
    • 70350629871 scopus 로고    scopus 로고
    • Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus
    • doi:10.1038/ng.472
    • Han JW, Zheng HF, Cui Y, Sun LD, Ye DQ, Hu Z, et al. Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet. 2009;41(11): 1234-7. doi: 10. 1038/ng. 472.
    • (2009) Nat Genet , vol.41 , Issue.11 , pp. 1234-1237
    • Han, J.W.1    Zheng, H.F.2    Cui, Y.3    Sun, L.D.4    Ye, D.Q.5    Hu, Z.6
  • 130
    • 79960934301 scopus 로고    scopus 로고
    • Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis
    • doi:10.1371/journal.pgen.1002091
    • Allanore Y, Saad M, Dieude P, Avouac J, Distler JH, Amouyel P, et al. Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis. PLoS Genet. 2011;7(7): e1002091. doi: 10. 1371/journal. pgen. 1002091.
    • (2011) PLoS Genet , vol.7 , Issue.7
    • Allanore, Y.1    Saad, M.2    Dieude, P.3    Avouac, J.4    Distler, J.H.5    Amouyel, P.6
  • 131
    • 48349136889 scopus 로고    scopus 로고
    • Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
    • doi:10.1038/ng.175
    • Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet. 2008;40(8): 955-62. doi: 10. 1038/ng. 175.
    • (2008) Nat Genet , vol.40 , Issue.8 , pp. 955-962
    • Barrett, J.C.1    Hansoul, S.2    Nicolae, D.L.3    Cho, J.H.4    Duerr, R.H.5    Rioux, J.D.6
  • 132
    • 77955398591 scopus 로고    scopus 로고
    • Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease
    • doi:10.1093/hmg/ddq248
    • McGovern DP, Jones MR, Taylor KD, Marciante K, Yan X, Dubinsky M, et al. Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. Hum Mol Genet. 2010;19(17): 3468-76. doi: 10. 1093/hmg/ddq248.
    • (2010) Hum Mol Genet , vol.19 , Issue.17 , pp. 3468-3476
    • McGovern, D.P.1    Jones, M.R.2    Taylor, K.D.3    Marciante, K.4    Yan, X.5    Dubinsky, M.6
  • 133
    • 34347338690 scopus 로고    scopus 로고
    • Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
    • doi:10.1038/ng2061
    • Parkes M, Barrett JC, Prescott NJ, Tremelling M, Anderson CA, Fisher SA, et al. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet. 2007;39(7): 830-2. doi: 10. 1038/ng2061.
    • (2007) Nat Genet , vol.39 , Issue.7 , pp. 830-832
    • Parkes, M.1    Barrett, J.C.2    Prescott, N.J.3    Tremelling, M.4    Anderson, C.A.5    Fisher, S.A.6
  • 134
    • 80051684615 scopus 로고    scopus 로고
    • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
    • International Multiple Sclerosis Genetics C, Wellcome Trust Case Control C, doi:10.1038/nature10251
    • International Multiple Sclerosis Genetics C, Wellcome Trust Case Control C, Sawcer S, Hellenthal G, Pirinen M, Spencer CC, et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature. 2011;476(7359): 214-9. doi: 10. 1038/nature10251.
    • (2011) Nature , vol.476 , Issue.7359 , pp. 214-219
    • Sawcer, S.1    Hellenthal, G.2    Pirinen, M.3    Spencer, C.C.4
  • 135
    • 79952195585 scopus 로고    scopus 로고
    • Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
    • doi:10.1038/ng.764
    • Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet. 2011;43(3): 246-52. doi: 10. 1038/ng. 764.
    • (2011) Nat Genet , vol.43 , Issue.3 , pp. 246-252
    • Anderson, C.A.1    Boucher, G.2    Lees, C.W.3    Franke, A.4    D'Amato, M.5    Taylor, K.D.6
  • 136
    • 12244281852 scopus 로고    scopus 로고
    • Interleukin-12 p40 gene (IL12B) 3′-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris
    • Tsunemi Y, Saeki H, Nakamura K, Sekiya T, Hirai K, Fujita H, et al. Interleukin-12 p40 gene (IL12B) 3′-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris. J Dermatol Sci. 2002;30(2): 161-6.
    • (2002) J Dermatol Sci , vol.30 , Issue.2 , pp. 161-166
    • Tsunemi, Y.1    Saeki, H.2    Nakamura, K.3    Sekiya, T.4    Hirai, K.5    Fujita, H.6
  • 137
    • 75749085686 scopus 로고    scopus 로고
    • Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci
    • doi:10.1038/ng.513
    • Reveille JD, Sims AM, Danoy P, Evans DM, Leo P, Pointon JJ, et al. Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. Nat Genet. 2010;42(2): 123-7. doi: 10. 1038/ng. 513.
    • (2010) Nat Genet , vol.42 , Issue.2 , pp. 123-127
    • Reveille, J.D.1    Sims, A.M.2    Danoy, P.3    Evans, D.M.4    Leo, P.5    Pointon, J.J.6
  • 138
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium, doi:10.1038/nature05911
    • Wellcome Trust Case Control Consortium. Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls. Nature. 2007;447(7145): 661-78. doi: 10. 1038/nature05911.
    • (2007) Nature , vol.447 , Issue.7145 , pp. 661-678
  • 139
    • 84863724842 scopus 로고    scopus 로고
    • 1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data
    • doi:10.1038/ejhg.2012.3
    • Huang J, Ellinghaus D, Franke A, Howie B, Li Y. 1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data. Eur J Hum Genet. 2012;20(7): 801-5. doi: 10. 1038/ejhg. 2012. 3.
    • (2012) Eur J Hum Genet , vol.20 , Issue.7 , pp. 801-805
    • Huang, J.1    Ellinghaus, D.2    Franke, A.3    Howie, B.4    Li, Y.5
  • 140
    • 84878550316 scopus 로고    scopus 로고
    • A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300
    • doi:10.1136/gutjnl-2012-302865
    • Julia A, Domenech E, Ricart E, Tortosa R, Garcia-Sanchez V, Gisbert JP, et al. A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300. Gut. 2013;62(10): 1440-5. doi: 10. 1136/gutjnl-2012-302865.
    • (2013) Gut , vol.62 , Issue.10 , pp. 1440-1445
    • Julia, A.1    Domenech, E.2    Ricart, E.3    Tortosa, R.4    Garcia-Sanchez, V.5    Gisbert, J.P.6
  • 141
    • 84859253322 scopus 로고    scopus 로고
    • A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci
    • doi:10.1371/journal.pgen.1002559
    • Kenny EE, Pe'er I, Karban A, Ozelius L, Mitchell AA, Ng SM, et al. A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. PLoS Genet. 2012;8(3): e1002559. doi: 10. 1371/journal. pgen. 1002559.
    • (2012) PLoS Genet , vol.8 , Issue.3
    • Kenny, E.E.1    Pe'er, I.2    Karban, A.3    Ozelius, L.4    Mitchell, A.A.5    Ng, S.M.6
  • 142
    • 34247554965 scopus 로고    scopus 로고
    • Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
    • doi:10.1038/ng2032
    • Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet. 2007;39(5): 596-604. doi: 10. 1038/ng2032.
    • (2007) Nat Genet , vol.39 , Issue.5 , pp. 596-604
    • Rioux, J.D.1    Xavier, R.J.2    Taylor, K.D.3    Silverberg, M.S.4    Goyette, P.5    Huett, A.6
  • 143
    • 35548958718 scopus 로고    scopus 로고
    • Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci
    • doi:10.1073/pnas.0706645104
    • Raelson JV, Little RD, Ruether A, Fournier H, Paquin B, van Eerdewegh P, et al. Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci. Proc Natl Acad Sci U S A. 2007;104(37): 14747-52. doi: 10. 1073/pnas. 0706645104.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.37 , pp. 14747-14752
    • Raelson, J.V.1    Little, R.D.2    Ruether, A.3    Fournier, H.4    Paquin, B.5    van Eerdewegh, P.6
  • 144
    • 34247579326 scopus 로고    scopus 로고
    • Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4
    • Libioulle C, Louis E, Hansoul S, Sandor C, Farnir F, Franchimont D, et al. Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13. 1 and modulates expression of PTGER4. PLoS Genet. 2007;3(4): e58.
    • (2007) PLoS Genet , vol.3 , Issue.4
    • Libioulle, C.1    Louis, E.2    Hansoul, S.3    Sandor, C.4    Farnir, F.5    Franchimont, D.6
  • 145
    • 52949091918 scopus 로고    scopus 로고
    • Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease
    • doi:10.1038/ng.203
    • Kugathasan S, Baldassano RN, Bradfield JP, Sleiman PM, Imielinski M, Guthery SL, et al. Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease. Nat Genet. 2008;40(10): 1211-5. doi: 10. 1038/ng. 203.
    • (2008) Nat Genet , vol.40 , Issue.10 , pp. 1211-1215
    • Kugathasan, S.1    Baldassano, R.N.2    Bradfield, J.P.3    Sleiman, P.M.4    Imielinski, M.5    Guthery, S.L.6
  • 146
    • 33845340501 scopus 로고    scopus 로고
    • A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
    • doi:10.1126/science.1135245
    • Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science. 2006;314(5804): 1461-3. doi: 10. 1126/science. 1135245.
    • (2006) Science , vol.314 , Issue.5804 , pp. 1461-1463
    • Duerr, R.H.1    Taylor, K.D.2    Brant, S.R.3    Rioux, J.D.4    Silverberg, M.S.5    Daly, M.J.6
  • 147
    • 59149087627 scopus 로고    scopus 로고
    • Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study
    • doi:10.1038/ng.275
    • Silverberg MS, Cho JH, Rioux JD, McGovern DP, Wu J, Annese V, et al. Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study. Nat Genet. 2009;41(2): 216-20. doi: 10. 1038/ng. 275.
    • (2009) Nat Genet , vol.41 , Issue.2 , pp. 216-220
    • Silverberg, M.S.1    Cho, J.H.2    Rioux, J.D.3    McGovern, D.P.4    Wu, J.5    Annese, V.6
  • 148
    • 77950298959 scopus 로고    scopus 로고
    • Genome-wide association identifies multiple ulcerative colitis susceptibility loci
    • doi:10.1038/ng.549
    • McGovern DP, Gardet A, Torkvist L, Goyette P, Essers J, Taylor KD, et al. Genome-wide association identifies multiple ulcerative colitis susceptibility loci. Nat Genet. 2010;42(4): 332-7. doi: 10. 1038/ng. 549.
    • (2010) Nat Genet , vol.42 , Issue.4 , pp. 332-337
    • McGovern, D.P.1    Gardet, A.2    Torkvist, L.3    Goyette, P.4    Essers, J.5    Taylor, K.D.6
  • 149
    • 77955087288 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behcet's disease
    • doi:10.1038/ng.625
    • Remmers EF, Cosan F, Kirino Y, Ombrello MJ, Abaci N, Satorius C, et al. Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behcet's disease. Nat Genet. 2010;42(8): 698-702. doi: 10. 1038/ng. 625.
    • (2010) Nat Genet , vol.42 , Issue.8 , pp. 698-702
    • Remmers, E.F.1    Cosan, F.2    Kirino, Y.3    Ombrello, M.J.4    Abaci, N.5    Satorius, C.6
  • 150
    • 77955091234 scopus 로고    scopus 로고
    • Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behcet's disease susceptibility loci
    • doi:10.1038/ng.624
    • Mizuki N, Meguro A, Ota M, Ohno S, Shiota T, Kawagoe T, et al. Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behcet's disease susceptibility loci. Nat Genet. 2010;42(8): 703-6. doi: 10. 1038/ng. 624.
    • (2010) Nat Genet , vol.42 , Issue.8 , pp. 703-706
    • Mizuki, N.1    Meguro, A.2    Ota, M.3    Ohno, S.4    Shiota, T.5    Kawagoe, T.6
  • 151
    • 67349199566 scopus 로고    scopus 로고
    • Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
    • doi:10.1038/ng.381
    • Barrett JC, Clayton DG, Concannon P, Akolkar B, Cooper JD, Erlich HA, et al. Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nat Genet. 2009;41(6): 703-7. doi: 10. 1038/ng. 381.
    • (2009) Nat Genet , vol.41 , Issue.6 , pp. 703-707
    • Barrett, J.C.1    Clayton, D.G.2    Concannon, P.3    Akolkar, B.4    Cooper, J.D.5    Erlich, H.A.6
  • 152
    • 34347341846 scopus 로고    scopus 로고
    • Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
    • doi:10.1038/ng2068
    • Todd JA, Walker NM, Cooper JD, Smyth DJ, Downes K, Plagnol V, et al. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet. 2007;39(7): 857-64. doi: 10. 1038/ng2068.
    • (2007) Nat Genet , vol.39 , Issue.7 , pp. 857-864
    • Todd, J.A.1    Walker, N.M.2    Cooper, J.D.3    Smyth, D.J.4    Downes, K.5    Plagnol, V.6
  • 153
    • 80053467892 scopus 로고    scopus 로고
    • Deletion of LCE3C and LCE3B genes is associated with psoriasis in a northern Chinese population
    • doi:10.1111/j.1365-2133.2011.10485.x
    • Xu L, Li Y, Zhang X, Sun H, Sun D, Jia X, et al. Deletion of LCE3C and LCE3B genes is associated with psoriasis in a northern Chinese population. Br J Dermatol. 2011;165(4): 882-7. doi: 10. 1111/j. 1365-2133. 2011. 10485. x.
    • (2011) Br J Dermatol , vol.165 , Issue.4 , pp. 882-887
    • Xu, L.1    Li, Y.2    Zhang, X.3    Sun, H.4    Sun, D.5    Jia, X.6
  • 154
    • 77952885768 scopus 로고    scopus 로고
    • A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility
    • doi:10.1038/ng.583
    • Kochi Y, Okada Y, Suzuki A, Ikari K, Terao C, Takahashi A, et al. A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility. Nat Genet. 2010;42(6): 515-9. doi: 10. 1038/ng. 583.
    • (2010) Nat Genet , vol.42 , Issue.6 , pp. 515-519
    • Kochi, Y.1    Okada, Y.2    Suzuki, A.3    Ikari, K.4    Terao, C.5    Takahashi, A.6
  • 155
    • 36549003138 scopus 로고    scopus 로고
    • Two independent alleles at 6q23 associated with risk of rheumatoid arthritis
    • doi:10.1038/ng.2007.27
    • Plenge RM, Cotsapas C, Davies L, Price AL, de Bakker PI, Maller J, et al. Two independent alleles at 6q23 associated with risk of rheumatoid arthritis. Nat Genet. 2007;39(12): 1477-82. doi: 10. 1038/ng. 2007. 27.
    • (2007) Nat Genet , vol.39 , Issue.12 , pp. 1477-1482
    • Plenge, R.M.1    Cotsapas, C.2    Davies, L.3    Price, A.L.4    de Bakker, P.I.5    Maller, J.6
  • 156
    • 77950243833 scopus 로고    scopus 로고
    • Multiple common variants for celiac disease influencing immune gene expression
    • doi:10.1038/ng.543
    • Dubois PC, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, et al. Multiple common variants for celiac disease influencing immune gene expression. Nat Genet. 2010;42(4): 295-302. doi: 10. 1038/ng. 543.
    • (2010) Nat Genet , vol.42 , Issue.4 , pp. 295-302
    • Dubois, P.C.1    Trynka, G.2    Franke, L.3    Hunt, K.A.4    Romanos, J.5    Curtotti, A.6
  • 157
    • 50449111452 scopus 로고    scopus 로고
    • Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus
    • doi:10.1038/ng.200
    • Graham RR, Cotsapas C, Davies L, Hackett R, Lessard CJ, Leon JM, et al. Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nat Genet. 2008;40(9): 1059-61. doi: 10. 1038/ng. 200.
    • (2008) Nat Genet , vol.40 , Issue.9 , pp. 1059-1061
    • Graham, R.R.1    Cotsapas, C.2    Davies, L.3    Hackett, R.4    Lessard, C.J.5    Leon, J.M.6
  • 158
    • 84873091770 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies new susceptibility loci for Behcet's disease and epistasis between HLA-B*51 and ERAP1
    • doi:10.1038/ng.2520
    • Kirino Y, Bertsias G, Ishigatsubo Y, Mizuki N, Tugal-Tutkun I, Seyahi E, et al. Genome-wide association analysis identifies new susceptibility loci for Behcet's disease and epistasis between HLA-B*51 and ERAP1. Nat Genet. 2013;45(2): 202-7. doi: 10. 1038/ng. 2520.
    • (2013) Nat Genet , vol.45 , Issue.2 , pp. 202-207
    • Kirino, Y.1    Bertsias, G.2    Ishigatsubo, Y.3    Mizuki, N.4    Tugal-Tutkun, I.5    Seyahi, E.6
  • 159
    • 77952888454 scopus 로고    scopus 로고
    • Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
    • doi:10.1038/ng.582
    • Stahl EA, Raychaudhuri S, Remmers EF, Xie G, Eyre S, Thomson BP, et al. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet. 2010;42(6): 508-14. doi: 10. 1038/ng. 582.
    • (2010) Nat Genet , vol.42 , Issue.6 , pp. 508-514
    • Stahl, E.A.1    Raychaudhuri, S.2    Remmers, E.F.3    Xie, G.4    Eyre, S.5    Thomson, B.P.6
  • 160
    • 67649880295 scopus 로고    scopus 로고
    • REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis
    • doi:10.1038/ng.395
    • Gregersen PK, Amos CI, Lee AT, Lu Y, Remmers EF, Kastner DL, et al. REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. Nat Genet. 2009;41(7): 820-3. doi: 10. 1038/ng. 395.
    • (2009) Nat Genet , vol.41 , Issue.7 , pp. 820-823
    • Gregersen, P.K.1    Amos, C.I.2    Lee, A.T.3    Lu, Y.4    Remmers, E.F.5    Kastner, D.L.6
  • 161
    • 45749143210 scopus 로고    scopus 로고
    • Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene
    • doi:10.1093/hmg/ddn091
    • Capon F, Bijlmakers MJ, Wolf N, Quaranta M, Huffmeier U, Allen M, et al. Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene. Hum Mol Genet. 2008;17(13): 1938-45. doi: 10. 1093/hmg/ddn091.
    • (2008) Hum Mol Genet , vol.17 , Issue.13 , pp. 1938-1945
    • Capon, F.1    Bijlmakers, M.J.2    Wolf, N.3    Quaranta, M.4    Huffmeier, U.5    Allen, M.6
  • 162
    • 84875234775 scopus 로고    scopus 로고
    • A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population
    • doi:10.1053/j.gastro.2012.12.021
    • Yamazaki K, Umeno J, Takahashi A, Hirano A, Johnson TA, Kumasaka N, et al. A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population. Gastroenterology. 2013;144(4): 781-8. doi: 10. 1053/j. gastro. 2012. 12. 021.
    • (2013) Gastroenterology , vol.144 , Issue.4 , pp. 781-788
    • Yamazaki, K.1    Umeno, J.2    Takahashi, A.3    Hirano, A.4    Johnson, T.A.5    Kumasaka, N.6
  • 163
    • 76049083598 scopus 로고    scopus 로고
    • Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene
    • doi:10.1016/j.ajhg.2010.01.017
    • Jakkula E, Leppa V, Sulonen AM, Varilo T, Kallio S, Kemppinen A, et al. Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 gene. Am J Hum Genet. 2010;86(2): 285-91. doi: 10. 1016/j. ajhg. 2010. 01. 017.
    • (2010) Am J Hum Genet , vol.86 , Issue.2 , pp. 285-291
    • Jakkula, E.1    Leppa, V.2    Sulonen, A.M.3    Varilo, T.4    Kallio, S.5    Kemppinen, A.6
  • 164
    • 56749183605 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci
    • doi:10.1038/ng.249
    • Cooper JD, Smyth DJ, Smiles AM, Plagnol V, Walker NM, Allen JE, et al. Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. Nat Genet. 2008;40(12): 1399-401. doi: 10. 1038/ng. 249.
    • (2008) Nat Genet , vol.40 , Issue.12 , pp. 1399-1401
    • Cooper, J.D.1    Smyth, D.J.2    Smiles, A.M.3    Plagnol, V.4    Walker, N.M.5    Allen, J.E.6
  • 165
    • 79953743757 scopus 로고    scopus 로고
    • Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production
    • doi:10.1371/journal.pgen.1001323
    • Chung SA, Taylor KE, Graham RR, Nititham J, Lee AT, Ortmann WA, et al. Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. PLoS Genet. 2011;7(3): e1001323. doi: 10. 1371/journal. pgen. 1001323.
    • (2011) PLoS Genet , vol.7 , Issue.3
    • Chung, S.A.1    Taylor, K.E.2    Graham, R.R.3    Nititham, J.4    Lee, A.T.5    Ortmann, W.A.6
  • 166
    • 79952262073 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci
    • doi:10.1371/journal.pgen.1002004
    • Zhernakova A, Stahl EA, Trynka G, Raychaudhuri S, Festen EA, Franke L, et al. Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. PLoS Genet. 2011;7(2): e1002004. doi: 10. 1371/journal. pgen. 1002004.
    • (2011) PLoS Genet , vol.7 , Issue.2
    • Zhernakova, A.1    Stahl, E.A.2    Trynka, G.3    Raychaudhuri, S.4    Festen, E.A.5    Franke, L.6
  • 167
    • 77649206245 scopus 로고    scopus 로고
    • Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus
    • doi:10.1371/journal.pgen.1000841
    • Yang W, Shen N, Ye DQ, Liu Q, Zhang Y, Qian XX, et al. Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus. PLoS Genet. 2010;6(2): e1000841. doi: 10. 1371/journal. pgen. 1000841.
    • (2010) PLoS Genet , vol.6 , Issue.2
    • Yang, W.1    Shen, N.2    Ye, D.Q.3    Liu, Q.4    Zhang, Y.5    Qian, X.X.6
  • 168
    • 41349103493 scopus 로고    scopus 로고
    • Newly identified genetic risk variants for celiac disease related to the immune response
    • doi:10.1038/ng.102
    • Hunt KA, Zhernakova A, Turner G, Heap GA, Franke L, Bruinenberg M, et al. Newly identified genetic risk variants for celiac disease related to the immune response. Nat Genet. 2008;40(4): 395-402. doi: 10. 1038/ng. 102.
    • (2008) Nat Genet , vol.40 , Issue.4 , pp. 395-402
    • Hunt, K.A.1    Zhernakova, A.2    Turner, G.3    Heap, G.A.4    Franke, L.5    Bruinenberg, M.6
  • 169
    • 79851490741 scopus 로고    scopus 로고
    • A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease
    • doi:10.1371/journal.pgen.1001283
    • Festen EA, Goyette P, Green T, Boucher G, Beauchamp C, Trynka G, et al. A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease. PLoS Genet. 2011;7(1): e1001283. doi: 10. 1371/journal. pgen. 1001283.
    • (2011) PLoS Genet , vol.7 , Issue.1
    • Festen, E.A.1    Goyette, P.2    Green, T.3    Boucher, G.4    Beauchamp, C.5    Trynka, G.6
  • 170
    • 34547454286 scopus 로고    scopus 로고
    • Genetic variations associated with diabetic nephropathy and type II diabetes in a Japanese population
    • doi:10.1038/sj.ki.5002385
    • Maeda S, Osawa N, Hayashi T, Tsukada S, Kobayashi M, Kikkawa R. Genetic variations associated with diabetic nephropathy and type II diabetes in a Japanese population. Kidney Int Suppl. 2007;106: S43-8. doi: 10. 1038/sj. ki. 5002385.
    • (2007) Kidney Int Suppl , vol.106
    • Maeda, S.1    Osawa, N.2    Hayashi, T.3    Tsukada, S.4    Kobayashi, M.5    Kikkawa, R.6
  • 171
    • 70649113728 scopus 로고    scopus 로고
    • Common variants at five new loci associated with early-onset inflammatory bowel disease
    • doi:10.1038/ng.489
    • Imielinski M, Baldassano RN, Griffiths A, Russell RK, Annese V, Dubinsky M, et al. Common variants at five new loci associated with early-onset inflammatory bowel disease. Nat Genet. 2009;41(12): 1335-40. doi: 10. 1038/ng. 489.
    • (2009) Nat Genet , vol.41 , Issue.12 , pp. 1335-1340
    • Imielinski, M.1    Baldassano, R.N.2    Griffiths, A.3    Russell, R.K.4    Annese, V.5    Dubinsky, M.6
  • 172
    • 58949099391 scopus 로고    scopus 로고
    • Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis
    • doi:10.1093/hmg/ddn388
    • Baranzini SE, Wang J, Gibson RA, Galwey N, Naegelin Y, Barkhof F, et al. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Hum Mol Genet. 2009;18(4): 767-78. doi: 10. 1093/hmg/ddn388.
    • (2009) Hum Mol Genet , vol.18 , Issue.4 , pp. 767-778
    • Baranzini, S.E.1    Wang, J.2    Gibson, R.A.3    Galwey, N.4    Naegelin, Y.5    Barkhof, F.6
  • 173
    • 77951565421 scopus 로고    scopus 로고
    • New insights in the immunologic basis of psoriasis
    • doi:10.1016/j.sder.2010.03.001
    • Nograles KE, Davidovici B, Krueger JG. New insights in the immunologic basis of psoriasis. Sem Cutan Med Surg. 2010;29(1): 3-9. doi: 10. 1016/j. sder. 2010. 03. 001.
    • (2010) Sem Cutan Med Surg , vol.29 , Issue.1 , pp. 3-9
    • Nograles, K.E.1    Davidovici, B.2    Krueger, J.G.3


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