메뉴 건너뛰기




Volumn 19, Issue 17, 2010, Pages 3468-3476

Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD GROUP A ANTIGEN; BLOOD GROUP B ANTIGEN; FUCOSYLTRANSFERASE; FUCOSYLTRANSFERASE 2; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 77955398591     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddq248     Document Type: Article
Times cited : (307)

References (76)
  • 1
    • 17144383927 scopus 로고    scopus 로고
    • Variable phenotypes of enterocolitis in interleukin 10-deficient mice monoassociated with two different commensal bacteria
    • Kim, S.C., Tonkonogy, S.L., Albright, C.A., Tsang, J., Balish, E.J., Braun, J., Huycke, M.M. and Sartor, R.B. (2005) Variable phenotypes of enterocolitis in interleukin 10-deficient mice monoassociated with two different commensal bacteria. Gastroenterology, 128, 891-906.
    • (2005) Gastroenterology , vol.128 , pp. 891-906
    • Kim, S.C.1    Tonkonogy, S.L.2    Albright, C.A.3    Tsang, J.4    Balish, E.J.5    Braun, J.6    Huycke, M.M.7    Sartor, R.B.8
  • 2
    • 9544226450 scopus 로고    scopus 로고
    • Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human beta2 microglobulin transgenic rats
    • Rath, H.C., Herfarth, H.H., Ikeda, J.S., Grenther, W.B., Hamm, T.E. Jr, Balish, E., Taurog, J.D., Hammer, R.E., Wilson, K.H. and Sartor, R.B. (1996) Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human beta2 microglobulin transgenic rats. J. Clin. Invest., 98, 945-953.
    • (1996) J. Clin. Invest. , vol.98 , pp. 945-953
    • Rath, H.C.1    Herfarth, H.H.2    Ikeda, J.S.3    Grenther, W.B.4    Hamm T.E., Jr.5    Balish, E.6    Taurog, J.D.7    Hammer, R.E.8    Wilson, K.H.9    Sartor, R.B.10
  • 3
    • 0032984363 scopus 로고    scopus 로고
    • Differential induction of colitis and gastritis in HLA-B27 transgenic rats selectively colonized with Bacteroides vulgatus or Escherichia coli
    • Rath, H.C., Wilson, K.H. and Sartor, R.B. (1999) Differential induction of colitis and gastritis in HLA-B27 transgenic rats selectively colonized with Bacteroides vulgatus or Escherichia coli. Infect. Immun., 67, 2969-2974.
    • (1999) Infect. Immun. , vol.67 , pp. 2969-2974
    • Rath, H.C.1    Wilson, K.H.2    Sartor, R.B.3
  • 4
    • 0032902274 scopus 로고    scopus 로고
    • Varying cecal bacterial loads influences colitis and gastritis in HLA-B27 transgenic rats
    • Rath, H.C., Ikeda, J.S., Linde, H.J., Scholmerich, J., Wilson, K.H. and Sartor, R.B. (1999) Varying cecal bacterial loads influences colitis and gastritis in HLA-B27 transgenic rats. Gastroenterology, 116, 310-319.
    • (1999) Gastroenterology , vol.116 , pp. 310-319
    • Rath, H.C.1    Ikeda, J.S.2    Linde, H.J.3    Scholmerich, J.4    Wilson, K.H.5    Sartor, R.B.6
  • 6
    • 0029079279 scopus 로고
    • Controlled trial of metronidazole treatment for prevention of Crohn's recurrence after ileal resection
    • Rutgeerts, P., Hiele, M., Geboes, K., Peeters, M., Penninckx, F., Aerts, R. and Kerremans, R. (1995) Controlled trial of metronidazole treatment for prevention of Crohn's recurrence after ileal resection. Gastroenterology, 108, 1617-1621.
    • (1995) Gastroenterology , vol.108 , pp. 1617-1621
    • Rutgeerts, P.1    Hiele, M.2    Geboes, K.3    Peeters, M.4    Penninckx, F.5    Aerts, R.6    Kerremans, R.7
  • 7
    • 0036726184 scopus 로고    scopus 로고
    • Selected loss of tolerance evidenced by Crohn's disease-associated immune responses to auto-and microbial antigens
    • Landers, C.J., Cohavy, O., Misra, R., Yang, H., Lin, Y.C., Braun, J. and Targan, S.R. (2002) Selected loss of tolerance evidenced by Crohn's disease-associated immune responses to auto-and microbial antigens. Gastroenterology, 123, 689-699.
    • (2002) Gastroenterology , vol.123 , pp. 689-699
    • Landers, C.J.1    Cohavy, O.2    Misra, R.3    Yang, H.4    Lin, Y.C.5    Braun, J.6    Targan, S.R.7
  • 17
    • 66149103305 scopus 로고    scopus 로고
    • High-frequency haplotypes in the X chromosome locus TLR8 are associated with both CD and UC in females
    • Saruta, M., Targan, S.R., Mei, L., Ippoliti, A.F., Taylor, K.D. and Rotter, J.I. (2009) High-frequency haplotypes in the X chromosome locus TLR8 are associated with both CD and UC in females. Inflamm. Bowel. Dis., 15, 321-327.
    • (2009) Inflamm. Bowel. Dis. , vol.15 , pp. 321-327
    • Saruta, M.1    Targan, S.R.2    Mei, L.3    Ippoliti, A.F.4    Taylor, K.D.5    Rotter, J.I.6
  • 20
    • 0034846424 scopus 로고    scopus 로고
    • Polymorphisms of two fucosyltransferase genes (Lewis and Secretor genes) involving type I Lewis antigens are associated with the presence of anti-Helicobacter pylori IgG antibody
    • Ikehara, Y., Nishihara, S., Yasutomi, H., Kitamura, T., Matsuo, K., Shimizu, N., Inada, K., Kodera, Y., Yamamura, Y., Narimatsu, H. et al. (2001) Polymorphisms of two fucosyltransferase genes (Lewis and Secretor genes) involving type I Lewis antigens are associated with the presence of anti-Helicobacter pylori IgG antibody. Cancer Epidemiol. Biomarkers Prev., 10, 971-977.
    • (2001) Cancer Epidemiol. Biomarkers Prev. , vol.10 , pp. 971-977
    • Ikehara, Y.1    Nishihara, S.2    Yasutomi, H.3    Kitamura, T.4    Matsuo, K.5    Shimizu, N.6    Inada, K.7    Kodera, Y.8    Yamamura, Y.9    Narimatsu, H.10
  • 21
    • 24644483568 scopus 로고    scopus 로고
    • Influence of the combined ABO, FUT2 and FUT3 polymorphism on susceptibility to Norwalk virus attachment
    • Marionneau, S., Airaud, F., Bovin, N.V., Le Pendu, J. and Ruvoen-Clouet, N. (2005) Influence of the combined ABO, FUT2 and FUT3 polymorphism on susceptibility to Norwalk virus attachment. J. Infect. Dis., 192, 1071-1077.
    • (2005) J. Infect. Dis. , vol.192 , pp. 1071-1077
    • Marionneau, S.1    Airaud, F.2    Bovin, N.V.3    Le Pendu, J.4    Ruvoen-Clouet, N.5
  • 22
    • 29744442306 scopus 로고    scopus 로고
    • A homozygous nonsense mutation (428G->A) in the human secretor (FUT2) gene provides resistance to symptomatic norovirus (GGII) infections
    • Thorven, M., Grahn, A., Hedlund, K.O., Johansson, H., Wahlfrid, C., Larson, G. and Svensson, L. (2005) A homozygous nonsense mutation (428G->A) in the human secretor (FUT2) gene provides resistance to symptomatic norovirus (GGII) infections. J. Virol., 79, 15351-15355.
    • (2005) J. Virol. , vol.79 , pp. 15351-15355
    • Thorven, M.1    Grahn, A.2    Hedlund, K.O.3    Johansson, H.4    Wahlfrid, C.5    Larson, G.6    Svensson, L.7
  • 24
    • 33745088359 scopus 로고    scopus 로고
    • A nonsense mutation (428G-> A) in the fucosyltransferase FUT2 gene affects the progression of HIV-1 infection
    • Kindberg, E., Hejdeman, B., Bratt, G., Wahren, B., Lindblom, B., Hinkula, J. and Svensson, L. (2006) A nonsense mutation (428G-> A) in the fucosyltransferase FUT2 gene affects the progression of HIV-1 infection. AIDS, 20, 685-689.
    • (2006) AIDS , vol.20 , pp. 685-689
    • Kindberg, E.1    Hejdeman, B.2    Bratt, G.3    Wahren, B.4    Lindblom, B.5    Hinkula, J.6    Svensson, L.7
  • 26
    • 0028965558 scopus 로고
    • Sequence and expression of a candidate for the human Secretor blood group alpha(1,2)fucosyltransferase gene (FUT2). Homozygosity for an enzyme-inactivating nonsense mutation commonly correlates with the non-secretor phenotype
    • Kelly, R.J., Rouquier, S., Giorgi, D., Lennon, G.G. and Lowe, J.B. (1995) Sequence and expression of a candidate for the human Secretor blood group alpha(1,2)fucosyltransferase gene (FUT2). Homozygosity for an enzyme-inactivating nonsense mutation commonly correlates with the non-secretor phenotype. J. Biol. Chem., 270, 4640-4649.
    • (1995) J. Biol. Chem. , vol.270 , pp. 4640-4649
    • Kelly, R.J.1    Rouquier, S.2    Giorgi, D.3    Lennon, G.G.4    Lowe, J.B.5
  • 27
    • 0014292196 scopus 로고
    • Influence of the ABO blood groups and secretor status on bleeding and on perforation of duodenal ulcer
    • Evans, D.A., Horwich, L., McConnell, R.B. and Bullen, M.F. (1968) Influence of the ABO blood groups and secretor status on bleeding and on perforation of duodenal ulcer. Gut, 9, 319-322.
    • (1968) Gut , vol.9 , pp. 319-322
    • Evans, D.A.1    Horwich, L.2    McConnell, R.B.3    Bullen, M.F.4
  • 30
    • 0014541431 scopus 로고
    • Streptococci, ABO blood groups, and secretor status
    • Haverkorn, M.J. and Goslings, W.R. (1969) Streptococci, ABO blood groups, and secretor status. Am. J. Hum. Genet., 21, 360-375.
    • (1969) Am. J. Hum. Genet. , vol.21 , pp. 360-375
    • Haverkorn, M.J.1    Goslings, W.R.2
  • 32
    • 0018173708 scopus 로고
    • Possible role of blood-group secretory substances in the aetiology of cholera
    • Chaudhuri, A. and DasAdhikary, C.R. (1978) Possible role of blood-group secretory substances in the aetiology of cholera. Trans. R. Soc. Trop. Med. Hyg., 72, 664-665.
    • (1978) Trans. R. Soc. Trop. Med. Hyg. , vol.72 , pp. 664-665
    • Chaudhuri, A.1    DasAdhikary, C.R.2
  • 33
    • 0022457402 scopus 로고
    • Non-secretion of ABO antigens predisposing to infection by Neisseria meningitidis and Streptococcus pneumoniae
    • Blackwell, C.C., Jonsdottir, K., Hanson, M., Todd, W.T., Chaudhuri, A.K., Mathew, B., Brettle, R.P. and Weir, D.M. (1986) Non-secretion of ABO antigens predisposing to infection by Neisseria meningitidis and Streptococcus pneumoniae. Lancet, 2, 284-285.
    • (1986) Lancet , vol.2 , pp. 284-285
    • Blackwell, C.C.1    Jonsdottir, K.2    Hanson, M.3    Todd, W.T.4    Chaudhuri, A.K.5    Mathew, B.6    Brettle, R.P.7    Weir, D.M.8
  • 34
    • 0022457390 scopus 로고
    • Non-secretion of ABO blood group antigens predisposing to infection by Haemophilus influenzae
    • Blackwell, C.C., Jonsdottir, K., Hanson, M.F. and Weir, D.M. (1986) Non-secretion of ABO blood group antigens predisposing to infection by Haemophilus influenzae. Lancet, 2, 687.
    • (1986) Lancet , vol.2 , pp. 687
    • Blackwell, C.C.1    Jonsdottir, K.2    Hanson, M.F.3    Weir, D.M.4
  • 37
    • 70349943834 scopus 로고    scopus 로고
    • STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
    • Ishikawa, H., Ma, Z. and Barber, G.N. (2009) STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature, 461, 788-792.
    • (2009) Nature , vol.461 , pp. 788-792
    • Ishikawa, H.1    Ma, Z.2    Barber, G.N.3
  • 41
    • 11144354272 scopus 로고    scopus 로고
    • Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs
    • van Heel, D.A., Fisher, S.A., Kirby, A., Daly, M.J., Rioux, J.D. and Lewis, C.M. (2004) Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs. Hum. Mol. Genet., 13, 763-770.
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 763-770
    • van Heel, D.A.1    Fisher, S.A.2    Kirby, A.3    Daly, M.J.4    Rioux, J.D.5    Lewis, C.M.6
  • 42
    • 0036399163 scopus 로고    scopus 로고
    • A novel single nucleotide polymorphism in the 3' untranslated region of human glutathione peroxidase 4 influences lipoxygenase metabolism
    • Villette, S., Kyle, J.A., Brown, K.M., Pickard, K., Milne, J.S., Nicol, F., Arthur, J.R. and Hesketh, J.E. (2002) A novel single nucleotide polymorphism in the 3' untranslated region of human glutathione peroxidase 4 influences lipoxygenase metabolism. Blood Cells Mol. Dis., 29, 174-178.
    • (2002) Blood Cells Mol. Dis. , vol.29 , pp. 174-178
    • Villette, S.1    Kyle, J.A.2    Brown, K.M.3    Pickard, K.4    Milne, J.S.5    Nicol, F.6    Arthur, J.R.7    Hesketh, J.E.8
  • 43
    • 34250709559 scopus 로고    scopus 로고
    • A hexanucleotide repeat upstream of eotaxin gene promoter is associated with asthma, serum total IgE and plasma eotaxin levels
    • Batra, J., Rajpoot, R., Ahluwalia, J., Devarapu, S.K., Sharma, S.K., Dinda, A.K. and Ghosh, B. (2007) A hexanucleotide repeat upstream of eotaxin gene promoter is associated with asthma, serum total IgE and plasma eotaxin levels. J. Med. Genet., 44, 397-403.
    • (2007) J. Med. Genet. , vol.44 , pp. 397-403
    • Batra, J.1    Rajpoot, R.2    Ahluwalia, J.3    Devarapu, S.K.4    Sharma, S.K.5    Dinda, A.K.6    Ghosh, B.7
  • 46
    • 59849117418 scopus 로고    scopus 로고
    • Enhanced CBir1-specific innate and adaptive immune responses in Crohn's disease
    • Shen, C., Landers, C.J., Derkowski, C., Elson, C.O. and Targan, S.R. (2008) Enhanced CBir1-specific innate and adaptive immune responses in Crohn's disease. Inflamm. Bowel. Dis., 14, 1641-1651.
    • (2008) Inflamm. Bowel. Dis. , vol.14 , pp. 1641-1651
    • Shen, C.1    Landers, C.J.2    Derkowski, C.3    Elson, C.O.4    Targan, S.R.5
  • 47
    • 0029993786 scopus 로고    scopus 로고
    • Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies to interleukin-12
    • Duchmann, R., Schmitt, E., Knolle, P., Meyer zum Buschenfelde, K.H. and Neurath, M. (1996) Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies to interleukin-12. Eur. J. Immunol., 26, 934-938.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 934-938
    • Duchmann, R.1    Schmitt, E.2    Knolle, P.3    Meyer zum Buschenfelde, K.H.4    Neurath, M.5
  • 48
    • 0035208811 scopus 로고    scopus 로고
    • Polymorphism of the human ABO-Secretor locus (FUT2) in four populations in Asia: indication of distinct Asian subpopulations
    • Pang, H., Koda, Y., Soejima, M., Fujitani, N., Ogaki, T., Saito, A., Kawasaki, T. and Kimura, H. (2001) Polymorphism of the human ABO-Secretor locus (FUT2) in four populations in Asia: indication of distinct Asian subpopulations. Ann. Hum. Genet., 65, 429-437.
    • (2001) Ann. Hum. Genet. , vol.65 , pp. 429-437
    • Pang, H.1    Koda, Y.2    Soejima, M.3    Fujitani, N.4    Ogaki, T.5    Saito, A.6    Kawasaki, T.7    Kimura, H.8
  • 50
    • 0037383017 scopus 로고    scopus 로고
    • Identification and screening for antimicrobial activity against Clostridium difficile of Bifidobacterium and Lactobacillus species isolated from healthy infant faeces
    • Lee, Y.J., Yu, W.K. and Heo, T.R. (2003) Identification and screening for antimicrobial activity against Clostridium difficile of Bifidobacterium and Lactobacillus species isolated from healthy infant faeces. Int. J. Antimicrob. Agents, 21, 340-346.
    • (2003) Int. J. Antimicrob. Agents , vol.21 , pp. 340-346
    • Lee, Y.J.1    Yu, W.K.2    Heo, T.R.3
  • 51
    • 60149112512 scopus 로고    scopus 로고
    • Lactobacilli facilitate maintenance of intestinal membrane integrity during Shigella dysenteriae 1 infection in rats
    • Moorthy, G., Murali, M.R. and Devaraj, S.N. (2009) Lactobacilli facilitate maintenance of intestinal membrane integrity during Shigella dysenteriae 1 infection in rats. Nutrition, 25, 350-358.
    • (2009) Nutrition , vol.25 , pp. 350-358
    • Moorthy, G.1    Murali, M.R.2    Devaraj, S.N.3
  • 52
    • 2642520426 scopus 로고    scopus 로고
    • Tissue-specific loss of fucosylated glycolipids in mice with targeted deletion of alpha(1,2)fucosyltransferase genes
    • Iwamori, M. and Domino, S.E. (2004) Tissue-specific loss of fucosylated glycolipids in mice with targeted deletion of alpha(1,2)fucosyltransferase genes. Biochem. J., 380, 75-81.
    • (2004) Biochem. J. , vol.380 , pp. 75-81
    • Iwamori, M.1    Domino, S.E.2
  • 53
    • 0035870140 scopus 로고    scopus 로고
    • Characterization of three members of murine alpha1,2-fucosyltransferases: Change in the expression of the Se gene in the intestine of mice after administration of microbes
    • Lin, B., Saito, M., Sakakibara, Y., Hayashi, Y., Yanagisawa, M. and Iwamori, M. (2001) Characterization of three members of murine alpha1,2-fucosyltransferases: change in the expression of the Se gene in the intestine of mice after administration of microbes. Arch. Biochem. Biophys., 388, 207-215.
    • (2001) Arch. Biochem. Biophys. , vol.388 , pp. 207-215
    • Lin, B.1    Saito, M.2    Sakakibara, Y.3    Hayashi, Y.4    Yanagisawa, M.5    Iwamori, M.6
  • 55
    • 34848880458 scopus 로고    scopus 로고
    • Role of commercial probiotic strains against human pathogen adhesion to intestinal mucus
    • Collado, M.C., Meriluoto, J. and Salminen, S. (2007) Role of commercial probiotic strains against human pathogen adhesion to intestinal mucus. Lett. Appl. Microbiol., 45, 454-460.
    • (2007) Lett. Appl. Microbiol. , vol.45 , pp. 454-460
    • Collado, M.C.1    Meriluoto, J.2    Salminen, S.3
  • 56
    • 39649100206 scopus 로고    scopus 로고
    • Active Crohn's disease and ulcerative colitis can be specifically diagnosed and monitored based on the biostructure of the fecal flora
    • Swidsinski, A., Loening-Baucke, V., Vaneechoutte, M. and Doerffel, Y. (2008) Active Crohn's disease and ulcerative colitis can be specifically diagnosed and monitored based on the biostructure of the fecal flora. Inflamm. Bowel Dis., 14, 147-161.
    • (2008) Inflamm. Bowel Dis. , vol.14 , pp. 147-161
    • Swidsinski, A.1    Loening-Baucke, V.2    Vaneechoutte, M.3    Doerffel, Y.4
  • 57
    • 3042552373 scopus 로고    scopus 로고
    • Increased susceptibility of secretor factor gene Fut2-null mice to experimental vaginal candidiasis
    • Hurd, E.A. and Domino, S.E. (2004) Increased susceptibility of secretor factor gene Fut2-null mice to experimental vaginal candidiasis. Infect. Immun., 72, 4279-4281.
    • (2004) Infect. Immun. , vol.72 , pp. 4279-4281
    • Hurd, E.A.1    Domino, S.E.2
  • 62
    • 34250378697 scopus 로고    scopus 로고
    • Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans
    • An, G., Wei, B., Xia, B., McDaniel, J.M., Ju, T., Cummings, R.D., Braun, J. and Xia, L. (2007) Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans. J. Exp. Med., 204, 1417-1429.
    • (2007) J. Exp. Med. , vol.204 , pp. 1417-1429
    • An, G.1    Wei, B.2    Xia, B.3    McDaniel, J.M.4    Ju, T.5    Cummings, R.D.6    Braun, J.7    Xia, L.8
  • 65
    • 0034433421 scopus 로고    scopus 로고
    • A DNA polymorphism influencing alpha(1,2)fucosyltransferase activity of the pig FUT1 enzyme determines susceptibility of small intestinal epithelium to Escherichia coli F18 adhesion
    • Meijerink, E., Neuenschwander, S., Fries, R., Dinter, A., Bertschinger, H.U., Stranzinger, G. and Vogeli, P. (2000) A DNA polymorphism influencing alpha(1,2)fucosyltransferase activity of the pig FUT1 enzyme determines susceptibility of small intestinal epithelium to Escherichia coli F18 adhesion. Immunogenetics, 52, 129-136.
    • (2000) Immunogenetics , vol.52 , pp. 129-136
    • Meijerink, E.1    Neuenschwander, S.2    Fries, R.3    Dinter, A.4    Bertschinger, H.U.5    Stranzinger, G.6    Vogeli, P.7
  • 69
    • 18144425478 scopus 로고    scopus 로고
    • A genome-wide scalable SNP genotyping assay using microarray technology
    • Gunderson, K.L., Steemers, F.J., Lee, G., Mendoza, L.G. and Chee, M.S. (2005) A genome-wide scalable SNP genotyping assay using microarray technology. Nat. Genet., 37, 549-554.
    • (2005) Nat. Genet. , vol.37 , pp. 549-554
    • Gunderson, K.L.1    Steemers, F.J.2    Lee, G.3    Mendoza, L.G.4    Chee, M.S.5
  • 72
    • 0032231375 scopus 로고    scopus 로고
    • Detecting marker-disease association by testing for Hardy-Weinberg disequilibrium at a marker locus
    • Nielsen, D.M., Ehm, M.G. and Weir, B.S. (1998) Detecting marker-disease association by testing for Hardy-Weinberg disequilibrium at a marker locus. Am. J. Hum. Genet., 63, 1531-1540.
    • (1998) Am. J. Hum. Genet. , vol.63 , pp. 1531-1540
    • Nielsen, D.M.1    Ehm, M.G.2    Weir, B.S.3
  • 73
    • 18944370235 scopus 로고    scopus 로고
    • Rational inferences about departures from Hardy-Weinberg equilibrium
    • Wittke-Thompson, J.K., Pluzhnikov, A. and Cox, N.J. (2005) Rational inferences about departures from Hardy-Weinberg equilibrium. Am. J. Hum. Genet., 76, 967-986.
    • (2005) Am. J. Hum. Genet. , vol.76 , pp. 967-986
    • Wittke-Thompson, J.K.1    Pluzhnikov, A.2    Cox, N.J.3
  • 74
    • 0035214299 scopus 로고    scopus 로고
    • Trimming, weighting, and grouping SNPs in human case-control association studies
    • Hoh, J., Wille, A. and Ott, J. (2001) Trimming, weighting, and grouping SNPs in human case-control association studies. Genome Res., 11, 2115-2119.
    • (2001) Genome Res. , vol.11 , pp. 2115-2119
    • Hoh, J.1    Wille, A.2    Ott, J.3
  • 75
    • 33645556520 scopus 로고    scopus 로고
    • A tail strength measure for assessing the overall univariate significance in a dataset
    • Taylor, J. and Tibshirani, R. (2006) A tail strength measure for assessing the overall univariate significance in a dataset. Biostatistics, 7, 167-181
    • (2006) Biostatistics , vol.7 , pp. 167-181
    • Taylor, J.1    Tibshirani, R.2
  • 76
    • 46149089380 scopus 로고    scopus 로고
    • A test for genetic association that incorporates information about deviation from Hardy-Weinberg proportions in cases
    • Wang, J. and Shete, S. (2008) A test for genetic association that incorporates information about deviation from Hardy-Weinberg proportions in cases. Am. J. Hum. Genet., 83, 53-63.
    • (2008) Am. J. Hum. Genet. , vol.83 , pp. 53-63
    • Wang, J.1    Shete, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.