Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis

Clinical Science

Volumn 129, Issue 8, 2015, Pages 721-739

  Afonso, Marta B ^a   Rodrigues, Pedro M ^a   Carvalho, Tânia ^b   Caridade, Marta ^a   Borralho, Paula ^c,d,e   Cortez Pinto, Helena ^f   Castro, Rui E ^a   Rodrigues, Cecília M P ^a  

^a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^b INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^c ESTeSL   (Portugal)

^d UNIVERSITY OF LISBON   (Portugal)

^e CUF Descobertas Hospital   (Portugal)

^f INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

Author keywords

Chronic liver diseases; Mixed lineage kinase domain like (MLKL); Necroptosis; Non alcoholic steatohepatitis (NASH); Oxidative stress; Receptor interacting protein 3 (RIP3)

Indexed keywords

CHOLINE; FAT; METHIONINE; MIXED LINEAGE KINASE; PROTEIN; RECEPTOR INTERACTING PROTEIN 3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; PALMITIC ACID; REACTIVE OXYGEN METABOLITE; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK3 PROTEIN, HUMAN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL LYSATE; CLINICAL ARTICLE; CONTROLLED STUDY; DIET; FEMALE; FIBROSIS; HUMAN; LIVER CELL; LIVER INJURY; MALE; NECROPTOSIS; NONALCOHOLIC FATTY LIVER; NONHUMAN; OXIDATIVE STRESS; PHOSPHORYLATION; PRIORITY JOURNAL; STEATOSIS; WILD TYPE; ANIMAL; C57BL MOUSE; CASE CONTROL STUDY; CELL DEATH; DEFICIENCY; DISEASE MODEL; LIPID DIET; LIVER; METABOLISM; MOUSE; NON-ALCOHOLIC FATTY LIVER DISEASE; PATHOLOGY; RAT; VITAMIN DEFICIENCY;

ANIMALS; CASE-CONTROL STUDIES; CELL DEATH; CHOLINE DEFICIENCY; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; HEPATOCYTES; HUMANS; LIVER; MALE; METHIONINE; MICE; MICE, INBRED C57BL; NON-ALCOHOLIC FATTY LIVER DISEASE; OXIDATIVE STRESS; PALMITIC ACID; RATS; REACTIVE OXYGEN SPECIES; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84942872734     PISSN: 01435221     EISSN: 14708736     Source Type: Journal    
DOI: 10.1042/CS20140732     Document Type: Article

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