-
1
-
-
84881075820
-
RIP3: A molecular switch for necrosis and inflammation
-
Moriwaki, K. and Chan, F. K. (2013) RIP3: a molecular switch for necrosis and inflammation. Genes Dev. 27, 1640-1649
-
(2013)
Genes Dev
, vol.27
, pp. 1640-1649
-
-
Moriwaki, K.1
Chan, F.K.2
-
2
-
-
84864240409
-
The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis
-
Li, J., McQuade, T., Siemer, A. B., Napetschnig, J., Moriwaki, K., Hsiao, Y. S., Damko, E., Moquin, D., Walz, T., McDermott, A. et al. (2012) The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis. Cell 150, 339-350
-
(2012)
Cell
, vol.150
, pp. 339-350
-
-
Li, J.1
McQuade, T.2
Siemer, A.B.3
Napetschnig, J.4
Moriwaki, K.5
Hsiao, Y.S.6
Damko, E.7
Moquin, D.8
Walz, T.9
McDermott, A.10
-
3
-
-
84862907788
-
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
-
Sun, L., Wang, H., Wang, Z., He, S., Chen, S., Liao, D., Wang, L., Yan, J., Liu, W., Lei, X. and Wang, X. (2012) Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 148, 213-227
-
(2012)
Cell
, vol.148
, pp. 213-227
-
-
Sun, L.1
Wang, H.2
Wang, Z.3
He, S.4
Chen, S.5
Liao, D.6
Wang, L.7
Yan, J.8
Liu, W.9
Lei, X.10
Wang, X.11
-
4
-
-
84859467770
-
Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis
-
Zhao, J., Jitkaew, S., Cai, Z., Choksi, S., Li, Q., Luo, J. and Liu, Z. G. (2012) Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis. Proc. Natl. Acad. Sci. U.S.A. 109, 5322-5327
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 5322-5327
-
-
Zhao, J.1
Jitkaew, S.2
Cai, Z.3
Choksi, S.4
Li, Q.5
Luo, J.6
Liu, Z.G.7
-
5
-
-
84862909353
-
The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways
-
Wang, Z., Jiang, H., Chen, S., Du, F. and Wang, X. (2012) The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell 148, 228-243
-
(2012)
Cell
, vol.148
, pp. 228-243
-
-
Wang, Z.1
Jiang, H.2
Chen, S.3
Du, F.4
Wang, X.5
-
6
-
-
84868531636
-
Fueling the flames: Mammalian programmed necrosis in inflammatory diseases
-
Chan, F. K. (2012) Fueling the flames: mammalian programmed necrosis in inflammatory diseases. Cold Spring Harbor Perspect. Biol. 4, a008805
-
(2012)
Cold Spring Harbor Perspect. Biol
, vol.4
-
-
Chan, F.K.1
-
7
-
-
84864389178
-
NEMO inhibits programmed necrosis in an NFkappaB-independent manner by restraining RIP1
-
O'Donnell, M. A., Hase, H., Legarda, D. and Ting, A. T. (2012) NEMO inhibits programmed necrosis in an NFkappaB-independent manner by restraining RIP1. PLoS ONE 7, e41238
-
(2012)
PLoS ONE
, vol.7
-
-
O'Donnell, M.A.1
Hase, H.2
Legarda, D.3
Ting, A.T.4
-
8
-
-
57649181391
-
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
-
Hitomi, J., Christofferson, D. E., Ng, A., Yao, J., Degterev, A., Xavier, R. J. and Yuan, J. (2008) Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 135, 1311-1323
-
(2008)
Cell
, vol.135
, pp. 1311-1323
-
-
Hitomi, J.1
Christofferson, D.E.2
Ng, A.3
Yao, J.4
Degterev, A.5
Xavier, R.J.6
Yuan, J.7
-
9
-
-
79952623655
-
CIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production
-
Vanlangenakker, N., Vanden Berghe, T., Bogaert, P., Laukens, B., Zobel, K., Deshayes, K., Vucic, D., Fulda, S., Vandenabeele, P. and Bertrand, M. J. (2011) cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production. Cell Death Differ. 18, 656-665
-
(2011)
Cell Death Differ
, vol.18
, pp. 656-665
-
-
Vanlangenakker, N.1
Vanden Berghe, T.2
Bogaert, P.3
Laukens, B.4
Zobel, K.5
Deshayes, K.6
Vucic, D.7
Fulda, S.8
Vandenabeele, P.9
Bertrand, M.J.10
-
10
-
-
0033214236
-
Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
-
Lin, Y., Devin, A., Rodriguez, Y. and Liu, Z. G. (1999) Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev. 13, 2514-2526
-
(1999)
Genes Dev
, vol.13
, pp. 2514-2526
-
-
Lin, Y.1
Devin, A.2
Rodriguez, Y.3
Liu, Z.G.4
-
11
-
-
34548437549
-
Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain
-
Feng, S., Yang, Y., Mei, Y., Ma, L., Zhu, D. E., Hoti, N., Castanares, M. and Wu, M. (2007) Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain. Cell. Signalling 19, 2056-2067
-
(2007)
Cell. Signalling
, vol.19
, pp. 2056-2067
-
-
Feng, S.1
Yang, Y.2
Mei, Y.3
Ma, L.4
Zhu, D.E.5
Hoti, N.6
Castanares, M.7
Wu, M.8
-
12
-
-
84856160569
-
Caspase 8 inhibits programmed necrosis by processing CYLD
-
O'Donnell, M. A., Perez-Jimenez, E., Oberst, A., Ng, A., Massoumi, R., Xavier, R., Green, D. R. and Ting, A. T. (2011) Caspase 8 inhibits programmed necrosis by processing CYLD. Nat. Cell Biol. 13, 1437-1442
-
(2011)
Nat. Cell Biol
, vol.13
, pp. 1437-1442
-
-
O'Donnell, M.A.1
Perez-Jimenez, E.2
Oberst, A.3
Ng, A.4
Massoumi, R.5
Xavier, R.6
Green, D.R.7
Ting, A.T.8
-
13
-
-
70350484946
-
Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease
-
Kovalenko, A., Kim, J. C., Kang, T. B., Rajput, A., Bogdanov, K., Dittrich-Breiholz, O., Kracht, M., Brenner, O. and Wallach, D. (2009) Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease. J. Exp. Med. 206, 2161-2177
-
(2009)
J. Exp. Med
, vol.206
, pp. 2161-2177
-
-
Kovalenko, A.1
Kim, J.C.2
Kang, T.B.3
Rajput, A.4
Bogdanov, K.5
Dittrich-Breiholz, O.6
Kracht, M.7
Brenner, O.8
Wallach, D.9
-
14
-
-
80052850704
-
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
-
Welz, P. S., Wullaert, A., Vlantis, K., Kondylis, V., Fernandez-Majada, V., Ermolaeva, M., Kirsch, P., A. Sterner-Kock, van Loo, G. and Pasparakis, M. (2011) FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. Nature 477, 330-334
-
(2011)
Nature
, vol.477
, pp. 330-334
-
-
Welz, P.S.1
Wullaert, A.2
Vlantis, K.3
Kondylis, V.4
Fernandez-Majada, V.5
Ermolaeva, M.6
Kirsch, P.7
Sterner-Kock, A.8
Van Loo, G.9
Pasparakis, M.10
-
15
-
-
80755132824
-
The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation
-
Bonnet, M. C., Preukschat, D., Welz, P. S., van Loo, G., Ermolaeva, M. A., Bloch, W., Haase, I. and Pasparakis, M. (2011) The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation. Immunity 35, 572-582
-
(2011)
Immunity
, vol.35
, pp. 572-582
-
-
Bonnet, M.C.1
Preukschat, D.2
Welz, P.S.3
Van Loo, G.4
Ermolaeva, M.A.5
Bloch, W.6
Haase, I.7
Pasparakis, M.8
-
16
-
-
84872764927
-
Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome
-
Kang, T. B., Yang, S. H., Toth, B., Kovalenko, A. and Wallach, D. (2013) Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. Immunity 38, 27-40
-
(2013)
Immunity
, vol.38
, pp. 27-40
-
-
Kang, T.B.1
Yang, S.H.2
Toth, B.3
Kovalenko, A.4
Wallach, D.5
-
17
-
-
79952780505
-
Functional complementation between FADD and RIP1 in embryos and lymphocytes
-
Zhang, H., Zhou, X., McQuade, T., Li, J., Chan, F. K. and Zhang, J. (2011) Functional complementation between FADD and RIP1 in embryos and lymphocytes. Nature 471, 373-376
-
(2011)
Nature
, vol.471
, pp. 373-376
-
-
Zhang, H.1
Zhou, X.2
McQuade, T.3
Li, J.4
Chan, F.K.5
Zhang, J.6
-
18
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
Kaiser, W. J., Upton, J. W., Long, A. B., Livingston-Rosanoff, D., Daley-Bauer, L. P., Hakem, R., Caspary, T. and Mocarski, E. S. (2011) RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 471, 368-372
-
(2011)
Nature
, vol.471
, pp. 368-372
-
-
Kaiser, W.J.1
Upton, J.W.2
Long, A.B.3
Livingston-Rosanoff, D.4
Daley-Bauer, L.P.5
Hakem, R.6
Caspary, T.7
Mocarski, E.S.8
-
19
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
-
Oberst, A., Dillon, C. P., Weinlich, R., McCormick, L. L., Fitzgerald, P., Pop, C., Hakem, R., Salvesen, G. S. and Green, D. R. (2011) Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 471, 363-367
-
(2011)
Nature
, vol.471
, pp. 363-367
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
McCormick, L.L.4
Fitzgerald, P.5
Pop, C.6
Hakem, R.7
Salvesen, G.S.8
Green, D.R.9
-
20
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho, Y. S., Challa, S., Moquin, D., Genga, R., Ray, T. D., Guildford, M. and Chan, F. K. (2009) Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 137, 1112-1123
-
(2009)
Cell
, vol.137
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
Genga, R.4
Ray, T.D.5
Guildford, M.6
Chan, F.K.7
-
21
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-α
-
He, S., Wang, L., Miao, L., Du, F., Zhao, L. and Wang, X. (2009) Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-α. Cell 137, 1100-1111
-
(2009)
Cell
, vol.137
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
Du, F.4
Zhao, L.5
Wang, X.6
-
22
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang, D. W., Shao, J., Lin, J., Zhang, N., Lu, B. J., Lin, S. C., Dong, M. Q. and Han, J. (2009) RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 325, 332-336
-
(2009)
Science
, vol.325
, pp. 332-336
-
-
Zhang, D.W.1
Shao, J.2
Lin, J.3
Zhang, N.4
Lu, B.J.5
Lin, S.C.6
Dong, M.Q.7
Han, J.8
-
23
-
-
42249102086
-
Identification of RIP1 kinase as a specific cellular target of necrostatins
-
Degterev, A., Hitomi, J., Germscheid, M., Ch'en, I. L., Korkina, O., Teng, X., Abbott, D., Cuny, G. D., Yuan, C., Wagner, G. et al. (2008) Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat. Chem. Biol. 4, 313-321
-
(2008)
Nat. Chem. Biol
, vol.4
, pp. 313-321
-
-
Degterev, A.1
Hitomi, J.2
Germscheid, M.3
Ch'En, I.L.4
Korkina, O.5
Teng, X.6
Abbott, D.7
Cuny, G.D.8
Yuan, C.9
Wagner, G.10
-
24
-
-
0347065342
-
A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses
-
Chan, F. K., Shisler, J., Bixby, J. G., Felices, M., Zheng, L., Appel, M., Orenstein, J., Moss, B. and Lenardo, M. J. (2003) A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses. J. Biol. Chem. 278, 51613-51621
-
(2003)
J. Biol. Chem
, vol.278
, pp. 51613-51621
-
-
Chan, F.K.1
Shisler, J.2
Bixby, J.G.3
Felices, M.4
Zheng, L.5
Appel, M.6
Orenstein, J.7
Moss, B.8
Lenardo, M.J.9
-
25
-
-
0033965946
-
A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes
-
Chan, F. K. and Lenardo, M. J. (2000) A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes. Eur. J. Immunol. 30, 652-660
-
(2000)
Eur. J. Immunol
, vol.30
, pp. 652-660
-
-
Chan, F.K.1
Lenardo, M.J.2
-
26
-
-
84874860953
-
Structural basis of RIP1 inhibition by necrostatins
-
Xie, T., Peng, W., Liu, Y., Yan, C., Maki, J., Degterev, A., Yuan, J. and Shi, Y. (2013) Structural basis of RIP1 inhibition by necrostatins. Structure 21, 493-499
-
(2013)
Structure
, vol.21
, pp. 493-499
-
-
Xie, T.1
Peng, W.2
Liu, Y.3
Yan, C.4
Maki, J.5
Degterev, A.6
Yuan, J.7
Shi, Y.8
-
27
-
-
84878755914
-
Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling
-
Chen, W., Zhou, Z., Li, L., Zhong, C. Q., Zheng, X., Wu, X., Zhang, Y., Ma, H., Huang, D., Li, W. et al. (2013) Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling. J. Biol. Chem. 288, 16247-16261
-
(2013)
J. Biol. Chem
, vol.288
, pp. 16247-16261
-
-
Chen, W.1
Zhou, Z.2
Li, L.3
Zhong, C.Q.4
Zheng, X.5
Wu, X.6
Zhang, Y.7
Ma, H.8
Huang, D.9
Li, W.10
-
28
-
-
77949314049
-
Nuclear factor-κB (NF-κB) is a novel positive transcriptional regulator of the oncogenic Wip1 phosphatase
-
Lowe, J. M., Cha, H., Yang, Q. and Fornace, Jr, A. J. (2010) Nuclear factor-κB (NF-κB) is a novel positive transcriptional regulator of the oncogenic Wip1 phosphatase. J. Biol. Chem. 285, 5249-5257
-
(2010)
J. Biol. Chem
, vol.285
, pp. 5249-5257
-
-
Lowe, J.M.1
Cha, H.2
Yang, Q.3
Fornace Jr., A.J.4
-
29
-
-
67349245931
-
WIP1 phosphatase is a negative regulator of NF-κB signalling
-
Chew, J., Biswas, S., Shreeram, S., Humaidi, M., Wong, E. T., Dhillion, M. K., Teo, H., Hazra, A., Fang, C. C., Lopez-Collazo, E. et al. (2009) WIP1 phosphatase is a negative regulator of NF-κB signalling. Nat. Cell Biol. 11, 659-666
-
(2009)
Nat. Cell Biol
, vol.11
, pp. 659-666
-
-
Chew, J.1
Biswas, S.2
Shreeram, S.3
Humaidi, M.4
Wong, E.T.5
Dhillion, M.K.6
Teo, H.7
Hazra, A.8
Fang, C.C.9
Lopez-Collazo, E.10
-
30
-
-
80051481307
-
RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation
-
Cho, Y., McQuade, T., Zhang, H. B., Zhang, J. K. and Chan, F. K. M. (2011) RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation. PLoS ONE 6, e23209
-
(2011)
PLoS ONE
, vol.6
-
-
Cho, Y.1
McQuade, T.2
Zhang, H.B.3
Zhang, J.K.4
Chan, F.K.M.5
-
31
-
-
84878964122
-
TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1
-
Moujalled, D. M., Cook, W. D., Okamoto, T., Murphy, J., Lawlor, K. E., Vince, J. E. and Vaux, D. L. (2013) TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1. Cell Death Dis. 4, e465
-
(2013)
Cell Death Dis
, vol.4
-
-
Moujalled, D.M.1
Cook, W.D.2
Okamoto, T.3
Murphy, J.4
Lawlor, K.E.5
Vince, J.E.6
Vaux, D.L.7
|