RIP3 inhibits inflammatory hepatocarcinogenesis but promotes cholestasis by controlling caspase-8- and JNK-dependent compensatory cell proliferation

Cell Reports

Volumn 4, Issue 4, 2013, Pages 776-790

  Vucur, Mihael ^a   Reisinger, Florian ^b   Gautheron, Jérémie ^a   Janssen, Joern ^a   Roderburg, Christoph ^a   Cardenas, David Vargas ^a   Kreggenwinkel, Karina ^a   Koppe, Christiane ^a   Hammerich, Linda ^a   Hakem, Razq ^c   Unger, Kristian ^b   Weber, Achim ^d   Gassler, Nikolaus ^a   Luedde, Mark ^e   Frey, Norbert ^e   Neumann, Ulf Peter ^a   Tacke, Frank ^a   Trautwein, Christian ^a   Heikenwalder, Mathias ^b,f   Luedde, Tom ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^e UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^f TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; RECEPTOR INTERACTING PROTEIN 3; REGULATOR PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER RESISTANCE; CELL PROLIFERATION; CELL TYPE; CHOLANGIOCYTE; CHOLESTASIS; CHROMOSOME ABERRATION; CHRONIC INFLAMMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; GENETIC MODEL; HEPATITIS; IMMUNOREGULATION; JAUNDICE; LIVER CANCER; LIVER CARCINOGENESIS; LIVER CELL; LIVER PARENCHYMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; STEM CELL;

ANIMALS; APOPTOSIS; CARCINOGENESIS; CARCINOMA, HEPATOCELLULAR; CASPASE 8; CELL PROLIFERATION; CHOLESTASIS; HEPATOCYTES; INFLAMMATION; JAUNDICE; LIVER; LIVER NEOPLASMS; MAP KINASE KINASE 4; MICE; MICE, KNOCKOUT; NECROSIS; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; STEM CELLS;

EID: 84883296695     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2013.07.035     Document Type: Article

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