Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease

EMBO Molecular Medicine

Volumn 7, Issue 10, 2015, Pages 1307-1326

  Hwang, Sunhee ^a   Disatnik, Marie Hélène ^a   Mochly Rosen, Daria ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Glyceraldehyde 3 phosphate dehydrogenase; Huntington's disease; Mitochondria; Mitophagy; Polyglutamine repeats

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HUNTINGTIN; POLYGLUTAMINE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE (NADP); HTT PROTEIN, MOUSE; NERVE PROTEIN; NUCLEAR PROTEIN; POLYGLUTAMIC ACID;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CELL SURVIVAL; CONTROLLED STUDY; HUNTINGTON CHOREA; LYSOSOME; MALE; MEMBRANE DAMAGE; MITOCHONDRIAL MEMBRANE; MITOPHAGY; MOLECULAR PATHOLOGY; MOUSE; NERVE CELL NECROSIS; NONHUMAN; OXIDATIVE STRESS; PC12 CELL LINE; PRIORITY JOURNAL; RAT; ANIMAL; BIOSYNTHESIS; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; MITOCHONDRION; PATHOPHYSIOLOGY;

ANIMALS; CELL SURVIVAL; GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE (NADP+); HUMANS; HUNTINGTIN PROTEIN; HUNTINGTON DISEASE; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PC12 CELLS; POLYGLUTAMIC ACID; RATS;

EID: 84942817626     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201505256     Document Type: Article

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