Tyrosyl-DNA-phosphodiesterase I (TDP1) participates in the removal and repair of stabilized-Top2α cleavage complexes in human cells

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 781, Issue , 2015, Pages 37-48

  Borda, Miguel Angel ^a   Palmitelli, Micaela ^a   Verón, Gustavo ^a   González Cid, Marcela ^a   de Campos Nebel, Marcelo ^a  

^a ACADEMIA NACIONAL DE MEDICINA   (Argentina)

Author keywords

DNA double strand break repair; Genome instability; Topoisomerase II mediated DNA damage; Tyrosyl DNA phosphodiesterase I

Indexed keywords

CHECKPOINT KINASE 1; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE (ATP HYDROLYSING) ALPHA; ETOPOSIDE; GAMMA HISTONE H2AX; HISTONE H2AX; PHOSPHODIESTERASE; PROTEIN PS296CHK1; TYROSYL DNA PHOSPHODIESTERASE 1; UNCLASSIFIED DRUG; 2-(MORPHOLIN-4-YL)BENZO(H)CHROMEN-4-ONE; CHROMONE DERIVATIVE; CRYSTAL VIOLET; DNA BINDING PROTEIN; DNA TOPOISOMERASE II ALPHA; H2AFX PROTEIN, HUMAN; HISTONE; MORPHOLINE DERIVATIVE; PRIMER DNA; TDP1 PROTEIN, HUMAN; TUMOR ANTIGEN;

ARTICLE; BIOACCUMULATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; CYTOGENETICS; DNA DAMAGE; DNA END JOINING REPAIR; GENOMIC INSTABILITY; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; MICRONUCLEUS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEPLETION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; CFU COUNTING; DEFICIENCY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HELA CELL LINE; IMMUNOBLOTTING; METABOLISM; MICRONUCLEUS TEST; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION;

ANTIGENS, NEOPLASM; CHROMONES; COLONY-FORMING UNITS ASSAY; DNA DAMAGE; DNA END-JOINING REPAIR; DNA PRIMERS; DNA TOPOISOMERASES, TYPE II; DNA-BINDING PROTEINS; ETOPOSIDE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENTIAN VIOLET; HELA CELLS; HISTONES; HUMANS; IMMUNOBLOTTING; MICRONUCLEUS TESTS; MORPHOLINES; PHOSPHORIC DIESTER HYDROLASES; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84942543568     PISSN: 00275107     EISSN: 18792871     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2015.09.003     Document Type: Article

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