Tyrosyl DNA phosphodiesterase 2, an enzyme fit for purpose

Nature Structural and Molecular Biology

Volumn 19, Issue 12, 2012, Pages 1212-1213

  Caldecott, Keith W ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMSACRINE; ANTINEOPLASTIC AGENT; DNA; DNA POLYMERASE; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; ETOPOSIDE; PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; RNA POLYMERASE; SUMO INTERACTION MOTIF PROTEIN; SUMO PROTEIN; TYROSYL DNA PHOSPHODIESTERASE 2; TYROSYL DNA PHOSPHODIESTERASE 2 INHIBITOR; UBIQUITIN; UBIQUITIN ASSOCIATED LIKE DOMAIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ALPHA HELIX; CARCINOGENESIS; CATALYSIS; CELL PROLIFERATION; COMPLEX FORMATION; DNA END JOINING REPAIR; DNA REPAIR; DNA REPLICATION; DNA SEQUENCE; DOUBLE STRANDED DNA BREAK; DRUG EFFICACY; DRUG HALF LIFE; ENZYME ACTIVITY; ENZYME SPECIFICITY; GENE DELETION; GENOME; HUMAN; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; SUMOYLATION; UBIQUITINATION;

ANIMALS; DNA ADDUCTS; DNA REPAIR; DNA TOPOISOMERASES, TYPE II; HUMANS; NUCLEAR PROTEINS; PHOSPHORIC DIESTER HYDROLASES; PHOSPHOTYROSINE; TRANSCRIPTION FACTORS;

EID: 84870775620     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2455     Document Type: Review

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