Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope

Journal of Virology

Volumn 78, Issue 24, 2004, Pages 13901-13910

  Peyerl, Fred W ^a   Bazick, Heidi S ^a   Newberg, Michael H ^a   Barouch, Dan H ^a   Sodroski, Joseph ^b,c,d   Letvin, Norman L ^a,c  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GAG PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; COST; CYTOTOXIC T LYMPHOCYTE; EVOLUTION; GENE SEQUENCE; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNE RESPONSE; MOLECULAR RECOGNITION; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS CAPSID; VIRUS IMMUNITY; VIRUS MUTATION; VIRUS REPLICATION;

AMINO ACID SEQUENCE; ANIMALS; CAPSID PROTEINS; CELL LINE; EPITOPES, T-LYMPHOCYTE; GENE PRODUCTS, GAG; HIV-1; HUMANS; MACACA MULATTA; MOLECULAR SEQUENCE DATA; POINT MUTATION; SEQUENCE ALIGNMENT; SIMIAN IMMUNODEFICIENCY VIRUS; T-LYMPHOCYTES, CYTOTOXIC; VIRUS REPLICATION;

EID: 10044227534     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.78.24.13901-13910.2004     Document Type: Article

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