-
2
-
-
84920768348
-
Type 2 diabetes and cancer: Umbrella review of meta-analyses of observational studies
-
Tsilidis KK, Kasimis JC, Lopez DS, et al. Type 2 diabetes and cancer: umbrella review of meta-analyses of observational studies. BMJ 2015; 350: g7607
-
(2015)
BMJ
, vol.350
, pp. g7607
-
-
Tsilidis, K.K.1
Kasimis, J.C.2
Lopez, D.S.3
-
3
-
-
84891552505
-
CARING (CAncer Risk and INsulin analoGues): The association of diabetes mellitus and cancer risk with focus on possible determinants-A systematic review and a meta-analysis
-
Starup-Linde J, Karlstad O, Eriksen SA, et al. CARING (CAncer Risk and INsulin analoGues): the association of diabetes mellitus and cancer risk with focus on possible determinants-A systematic review and a meta-analysis. Curr Drug Saf 2013; 8: 296-332
-
(2013)
Curr Drug Saf
, vol.8
, pp. 296-332
-
-
Starup-Linde, J.1
Karlstad, O.2
Eriksen, S.A.3
-
4
-
-
47349117519
-
Hyper-insulinaemia and cancer, meta-analyses of epidemiological studies
-
Pisani P. Hyper-insulinaemia and cancer, meta-analyses of epidemiological studies. Arch Physiol Biochem 2008; 114: 63-70
-
(2008)
Arch Physiol Biochem
, vol.114
, pp. 63-70
-
-
Pisani, P.1
-
6
-
-
77953545296
-
Central adiposity, systemic inflammation, and the metabolic syndrome
-
Elks CM and Francis J. Central adiposity, systemic inflammation, and the metabolic syndrome. Curr Hypertens Rep 2010; 12: 99-104
-
(2010)
Curr Hypertens Rep
, vol.12
, pp. 99-104
-
-
Elks, C.M.1
Francis, J.2
-
7
-
-
84904722547
-
Obesity and cancer-mechanisms underlying tumour progression and recurrence
-
Park J, Morley TS, Kim M, et al. Obesity and cancer-mechanisms underlying tumour progression and recurrence. Nat Rev Endocrinol 2014; 10: 455-65
-
(2014)
Nat Rev Endocrinol
, vol.10
, pp. 455-465
-
-
Park, J.1
Morley, T.S.2
Kim, M.3
-
8
-
-
20444461067
-
Metformin and reduced risk of cancer in diabetic patients
-
Evans JM, Donnelly LA, Emslie-Smith AM, et al. Metformin and reduced risk of cancer in diabetic patients. BMJ 2005; 330: 1304-5
-
(2005)
BMJ
, vol.330
, pp. 1304-1305
-
-
Evans, J.M.1
Donnelly, L.A.2
Emslie-Smith, A.M.3
-
9
-
-
33645766204
-
Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin
-
Bowker SL, Majumdar SR, Veugelers P, Johnson JA. Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin. Diabetes Care 2006; 29: 254-8
-
(2006)
Diabetes Care
, vol.29
, pp. 254-258
-
-
Bowker, S.L.1
Majumdar, S.R.2
Veugelers, P.3
Johnson, J.A.4
-
10
-
-
67749144226
-
Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer
-
Jiralerspong S, Palla SL, Giordano SH, et al. Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer. J Clin Oncol 2009; 27: 3297-302
-
(2009)
J Clin Oncol
, vol.27
, pp. 3297-3302
-
-
Jiralerspong, S.1
Palla, S.L.2
Giordano, S.H.3
-
11
-
-
84864075329
-
Dual effect of metformin on breast cancer proliferation in a randomized presurgical trial
-
Bonanni B, Puntoni M, Cazzaniga M, et al. Dual effect of metformin on breast cancer proliferation in a randomized presurgical trial. J Clin Oncol 2012; 30: 2593-600
-
(2012)
J Clin Oncol
, vol.30
, pp. 2593-2600
-
-
Bonanni, B.1
Puntoni, M.2
Cazzaniga, M.3
-
13
-
-
0344420380
-
Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus: Systematic review and meta-analysis
-
Salpeter SR, Greyber E, Pasternak GA, Salpeter EE. Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus: systematic review and meta-analysis. Arch Intern Med 2003; 163: 2594-602
-
(2003)
Arch Intern Med
, vol.163
, pp. 2594-2602
-
-
Salpeter, S.R.1
Greyber, E.2
Pasternak, G.A.3
Salpeter, E.E.4
-
14
-
-
77949703788
-
Metformin: A therapeutic opportunity in breast cancer
-
Gonzalez-Angulo AM, Meric-Bernstam F. Metformin: a therapeutic opportunity in breast cancer. Clin Cancer Res 2010; 16 (6): 1695-700
-
(2010)
Clin Cancer Res
, vol.16
, Issue.6
, pp. 1695-1700
-
-
Gonzalez-Angulo, A.M.1
Meric-Bernstam, F.2
-
15
-
-
77956401999
-
Metformin and other biguanides in oncology: Advancing the research agenda
-
Pollak M. Metformin and other biguanides in oncology: advancing the research agenda. Cancer Prev Res (Phila) 2010; 3 (9): 1060-5
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, Issue.9
, pp. 1060-1065
-
-
Pollak, M.1
-
16
-
-
84919615360
-
Metformin: From mechanisms of action to therapies
-
Foretz M, Guigas B, Bertrand L, et al. Metformin: from mechanisms of action to therapies. Cell Metab 2014; 20 (6): 953-66
-
(2014)
Cell Metab
, vol.20
, Issue.6
, pp. 953-966
-
-
Foretz, M.1
Guigas, B.2
Bertrand, L.3
-
17
-
-
84905757105
-
Metformin-mode of action and clinical implications for diabetes and cancer
-
Pernicova I, Korbonits M. Metformin-mode of action and clinical implications for diabetes and cancer. Nat Rev Endocrinol 2014; 10 (3): 143-56
-
(2014)
Nat Rev Endocrinol
, vol.10
, Issue.3
, pp. 143-156
-
-
Pernicova, I.1
Korbonits, M.2
-
18
-
-
84857640868
-
The insulin and insulin-like growth factor receptor family in neoplasia: An update
-
Pollak M. The insulin and insulin-like growth factor receptor family in neoplasia: an update. Nat Rev Cancer 2012; 12 (3): 159-69
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.3
, pp. 159-169
-
-
Pollak, M.1
-
19
-
-
84866322945
-
Investigating metformin for cancer prevention and treatment: The end of the beginning
-
Pollak MN. Investigating metformin for cancer prevention and treatment: the end of the beginning. Cancer Discov 2012; 2 (9): 778-90
-
(2012)
Cancer Discov
, vol.2
, Issue.9
, pp. 778-790
-
-
Pollak, M.N.1
-
20
-
-
84883542202
-
Potential applications for biguanides in oncology
-
Pollak M. Potential applications for biguanides in oncology. J Clin Invest 2013; 123 (9): 3693-700
-
(2013)
J Clin Invest
, vol.123
, Issue.9
, pp. 3693-3700
-
-
Pollak, M.1
-
21
-
-
4043171462
-
Upstream and downstream of mTOR
-
Hay N, Sonenberg N. Upstream and downstream of mTOR. Genes Dev 2004; 18 (16): 1926-45
-
(2004)
Genes Dev
, vol.18
, Issue.16
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
22
-
-
0344081177
-
Minireview: The AMP-activated protein kinase cascade: The key sensor of cellular energy status
-
Hardie DG. Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status. Endocrinology 2003; 144 (12): 5179-83
-
(2003)
Endocrinology
, vol.144
, Issue.12
, pp. 5179-5183
-
-
Hardie, D.G.1
-
23
-
-
28844433635
-
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
-
Shaw RJ, Lamia KA, Vasquez D, et al. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science 2005; 310 (5754): 1642-6
-
(2005)
Science
, vol.310
, Issue.5754
, pp. 1642-1646
-
-
Shaw, R.J.1
Lamia, K.A.2
Vasquez, D.3
-
24
-
-
0036324142
-
The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism
-
Hawley SA, Gadalla AE, Olsen GS, Hardie DG. The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism. Diabetes 2002; 51 (8): 2420-5
-
(2002)
Diabetes
, vol.51
, Issue.8
, pp. 2420-2425
-
-
Hawley, S.A.1
Gadalla, A.E.2
Olsen, G.S.3
Hardie, D.G.4
-
25
-
-
67749111502
-
The LKB1-AMPK pathway: Metabolism and growth control in tumour suppression
-
Shackelford DB, Shaw RJ. The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nat Rev Cancer 2009; 9 (8): 563-75
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.8
, pp. 563-575
-
-
Shackelford, D.B.1
Shaw, R.J.2
-
26
-
-
84858719140
-
Metformin as an energy restriction mimetic agent for breast cancer prevention
-
Zhu Z, Jiang W, Thompson MD, et al. Metformin as an energy restriction mimetic agent for breast cancer prevention. J Carcinog 2011; 10: 17
-
(2011)
J Carcinog
, vol.10
, pp. 17
-
-
Zhu, Z.1
Jiang, W.2
Thompson, M.D.3
-
27
-
-
0034659785
-
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
-
Owen MR, Doran E, Halestrap AP. Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochem J 2000; 348 (Pt 3): 607-14
-
(2000)
Biochem J
, vol.348
, pp. 607-614
-
-
Owen, M.R.1
Doran, E.2
Halestrap, A.P.3
-
28
-
-
79952538201
-
Diet and tumor LKB1 expression interact to determine sensitivity to anti-neoplastic effects of metformin in vivo
-
Algire C, Amrein L, Bazile M, et al. Diet and tumor LKB1 expression interact to determine sensitivity to anti-neoplastic effects of metformin in vivo. Oncogene 2011; 30 (10): 1174-82
-
(2011)
Oncogene
, vol.30
, Issue.10
, pp. 1174-1182
-
-
Algire, C.1
Amrein, L.2
Bazile, M.3
-
29
-
-
33748118458
-
Neither LKB1 nor AMPK are the direct targets of metformin
-
author reply 974-5
-
Hardie DG. Neither LKB1 nor AMPK are the direct targets of metformin. Gastroenterology 2006; 131 (3): 973; author reply 974-5
-
(2006)
Gastroenterology
, vol.131
, Issue.3
, pp. 973
-
-
Hardie, D.G.1
-
30
-
-
84921405225
-
Metformin in cancer treatment and prevention
-
Morales DR, Morris AD. Metformin in cancer treatment and prevention. Annu Rev Med 2015; 66: 17-29
-
(2015)
Annu Rev Med
, vol.66
, pp. 17-29
-
-
Morales, D.R.1
Morris, A.D.2
-
31
-
-
84903977464
-
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin
-
Chen L, Shu Y, Liang X, et al. OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin. Proc Natl Acad Sci USA 2014; 111 (27): 9983-8
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, Issue.27
, pp. 9983-9988
-
-
Chen, L.1
Shu, Y.2
Liang, X.3
-
32
-
-
77956415337
-
Metformin prevents tobacco carcinogen-induced lung tumorigenesis
-
Memmott RM, Mercado JR, Maier CR, et al. Metformin prevents tobacco carcinogen-induced lung tumorigenesis. Cancer Prev Res (Phila) 2010; 3 (9): 1066-76
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, Issue.9
, pp. 1066-1076
-
-
Memmott, R.M.1
Mercado, J.R.2
Maier, C.R.3
-
33
-
-
77955511122
-
Cancer and diabetes: Are we ready for prime time
-
Smith U, Gale EA. Cancer and diabetes: are we ready for prime time? Diabetologia 2010; 53: 1541-34
-
(2010)
Diabetologia
, vol.53
, pp. 1541-1634
-
-
Smith, U.1
Gale, E.A.2
-
36
-
-
84906691535
-
Metformin does not affect cancer risk: A cohort study in the U.K. Clinical practice research datalink analyzed like an intention-to-treat trial
-
Tsilidis K, Capothanassi D, Allen NE, et al. Metformin does not affect cancer risk: a cohort study in the U.K. clinical practice research datalink analyzed like an intention-to-treat trial. Diabetes Care 2014; 37: 2522-32
-
(2014)
Diabetes Care
, vol.37
, pp. 2522-2532
-
-
Tsilidis, K.1
Capothanassi, D.2
Allen, N.E.3
-
37
-
-
84883165443
-
Repositioning metformin for cancer prevention and treatment
-
Quinn BJ, Kitagawa H, Memmott RM, et al. Repositioning metformin for cancer prevention and treatment. Trends Endocrinol Metab 2013; 24: 469-80
-
(2013)
Trends Endocrinol Metab
, vol.24
, pp. 469-480
-
-
Quinn, B.J.1
Kitagawa, H.2
Memmott, R.M.3
-
38
-
-
84907296915
-
Metformin and cancer risk and mortality: A systematic review and meta-analysis taking into account biases and confounders
-
Gandini S, Puntoni M, Heckman-Stoddard BM, et al. Metformin and cancer risk and mortality: a systematic review and meta-analysis taking into account biases and confounders. Cancer Prev Res (Phila) 2014; 7: 867-85
-
(2014)
Cancer Prev Res (Phila)
, vol.7
, pp. 867-885
-
-
Gandini, S.1
Puntoni, M.2
Heckman-Stoddard, B.M.3
-
39
-
-
84879552899
-
Metformin and sulfonylureas in relation to cancer risk in type II diabetes patients: A meta-analysis using primary data of published studies
-
Thakkar B, Aronis KN, Vamvini MT, et al. Metformin and sulfonylureas in relation to cancer risk in type II diabetes patients: a meta-analysis using primary data of published studies. Metabolism 2013; 62: 922-34
-
(2013)
Metabolism
, vol.62
, pp. 922-934
-
-
Thakkar, B.1
Aronis, K.N.2
Vamvini, M.T.3
-
40
-
-
78649302320
-
Metformin and cancer risk in diabetic patients: A systematic review and meta-analysis
-
Decensi A, Puntoni M, Goodwin P, et al. Metformin and cancer risk in diabetic patients: a systematic review and meta-analysis. Cancer Prev Res (Phila) 2010; 3: 1451-61
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 1451-1461
-
-
Decensi, A.1
Puntoni, M.2
Goodwin, P.3
-
42
-
-
83555164657
-
Metformin and neoplasia: Implications and indications
-
Aljada A, Mousa SA. Metformin and neoplasia: implications and indications. Pharmacol Ther 2012; 133: 108-15
-
(2012)
Pharmacol Ther
, vol.133
, pp. 108-115
-
-
Aljada, A.1
Mousa, S.A.2
-
43
-
-
60549102941
-
Insulin-lowering effects of metformin in women with early breast cancer
-
Goodwin PJ, Pritchard KI, Ennis M, et al. Insulin-lowering effects of metformin in women with early breast cancer. Clin Breast Cancer 2008; 8: 501-5
-
(2008)
Clin Breast Cancer
, vol.8
, pp. 501-505
-
-
Goodwin, P.J.1
Pritchard, K.I.2
Ennis, M.3
-
44
-
-
84930404106
-
Effect of metformin vs placebo on and metabolic factors in NCIC CTG MA.32
-
Goodwin PJ, Parulekar WR, Gelmon KA, et al. Effect of metformin vs placebo on and metabolic factors in NCIC CTG MA.32. J Natl Cancer Inst 2015; 107
-
(2015)
J Natl Cancer Inst
, vol.107
-
-
Goodwin, P.J.1
Parulekar, W.R.2
Gelmon, K.A.3
-
45
-
-
84861155928
-
Effect of different doses of metformin on serum testosterone and insulin in non-diabetic women with breast cancer: A randomized study
-
Campagnoli C, Pasanisi P, Abba C, et al. Effect of different doses of metformin on serum testosterone and insulin in non-diabetic women with breast cancer: a randomized study. Clin Breast Cancer 2012; 12: 175-82
-
(2012)
Clin Breast Cancer
, vol.12
, pp. 175-182
-
-
Campagnoli, C.1
Pasanisi, P.2
Abba, C.3
-
46
-
-
84889066710
-
Metformin decreases circulating androgen and estrogen levels in nondiabetic women with breast cancer
-
Campagnoli C, Berrino F, Venturelli E, et al. Metformin decreases circulating androgen and estrogen levels in nondiabetic women with breast cancer. Clin Breast Cancer 2013; 13: 433-8
-
(2013)
Clin Breast Cancer
, vol.13
, pp. 433-438
-
-
Campagnoli, C.1
Berrino, F.2
Venturelli, E.3
-
47
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G, Myers R, Li Y, et al. Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 2001; 108: 1167-74
-
(2001)
J Clin Invest
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
-
48
-
-
84888870836
-
The effect of metformin on apoptosis in a breast cancer presurgical trial
-
Cazzaniga M, Decensi A, Pruneri G, et al. The effect of metformin on apoptosis in a breast cancer presurgical trial. Br J Cancer 2013; 109: 2792-7
-
(2013)
Br J Cancer
, vol.109
, pp. 2792-2797
-
-
Cazzaniga, M.1
Decensi, A.2
Pruneri, G.3
-
49
-
-
84922005443
-
Differential effects of metformin on breast cancer proliferation according to markers of insulin resistance and tumor subtype in a randomized presurgical trial
-
Decensi A, Puntoni M, Gandini S, et al. Differential effects of metformin on breast cancer proliferation according to markers of insulin resistance and tumor subtype in a randomized presurgical trial. Breast Cancer Res Treat 2014; 148: 81-90
-
(2014)
Breast Cancer Res Treat
, vol.148
, pp. 81-90
-
-
Decensi, A.1
Puntoni, M.2
Gandini, S.3
-
50
-
-
84866538325
-
Metformin in early breast cancer: A prospective window of opportunity neoadjuvant study
-
Niraula S, Dowling RJ, Ennis M, et al. Metformin in early breast cancer: a prospective window of opportunity neoadjuvant study. Breast Cancer Res Treat 2012; 135: 821-30
-
(2012)
Breast Cancer Res Treat
, vol.135
, pp. 821-830
-
-
Niraula, S.1
Dowling, R.J.2
Ennis, M.3
-
51
-
-
84898740537
-
Presurgical trial of metformin in overweight and obese patients with newly diagnosed breast cancer
-
Kalinsky K, Crew KD, Refice S, et al. Presurgical trial of metformin in overweight and obese patients with newly diagnosed breast cancer. Cancer Invest 2014; 32: 150-7
-
(2014)
Cancer Invest
, vol.32
, pp. 150-157
-
-
Kalinsky, K.1
Crew, K.D.2
Refice, S.3
-
52
-
-
84872279633
-
Phase i trial of exemestane in combination with metformin and rosiglitazone in nondiabetic obese postmenopausal women with hormone receptor-positive metastatic breast cancer
-
Esteva FJ, Moulder SL, Gonzalez-Angulo AM, et al. Phase I trial of exemestane in combination with metformin and rosiglitazone in nondiabetic obese postmenopausal women with hormone receptor-positive metastatic breast cancer. Cancer Chemother Pharmacol 2013; 71: 63-72
-
(2013)
Cancer Chemother Pharmacol
, vol.71
, pp. 63-72
-
-
Esteva, F.J.1
Moulder, S.L.2
Gonzalez-Angulo, A.M.3
-
53
-
-
67349141286
-
Endometrial cancer and obesity: Epidemiology, biomarkers, prevention and survivorship
-
Fader AN, Arriba LN, Frasure HE, von Gruenigen VE. Endometrial cancer and obesity: epidemiology, biomarkers, prevention and survivorship. Gynecol Oncol 2009; 114: 121-7
-
(2009)
Gynecol Oncol
, vol.114
, pp. 121-127
-
-
Fader, A.N.1
Arriba, L.N.2
Frasure, H.E.3
Von Gruenigen, V.E.4
-
54
-
-
84892735827
-
Metformin use and endometrial cancer survival
-
Nevadunsky NS, Van AA, Strickler HD, et al. Metformin use and endometrial cancer survival. Gynecol Oncol 2014; 132: 236-40
-
(2014)
Gynecol Oncol
, vol.132
, pp. 236-240
-
-
Nevadunsky, N.S.1
Van Aa Strickler, H.D.2
-
55
-
-
70749106139
-
Metformin is a potent inhibitor of endometrial cancer cell proliferation-implications for a novel treatment strategy
-
Cantrell LA, Zhou C, Mendivil A, et al. Metformin is a potent inhibitor of endometrial cancer cell proliferation-implications for a novel treatment strategy. Gynecol Oncol 2010; 116: 92-8
-
(2010)
Gynecol Oncol
, vol.116
, pp. 92-98
-
-
Cantrell, L.A.1
Zhou, C.2
Mendivil, A.3
-
56
-
-
84908498848
-
Effects of metformin on endometrial cancer cell growth in vivo: A preoperative prospective trial
-
Mitsuhashi A, Kiyokawa T, Sato Y, Shozu M. Effects of metformin on endometrial cancer cell growth in vivo: a preoperative prospective trial. Cancer 2014; 120: 2986-95
-
(2014)
Cancer
, vol.120
, pp. 2986-2995
-
-
Mitsuhashi, A.1
Kiyokawa, T.2
Sato, Y.3
Shozu, M.4
-
57
-
-
84908342070
-
Anti-diabetic doses of metformin decrease proliferation markers in tumors of patients with endometrial cancer
-
Laskov I, Drudi L, Beauchamp MC, et al. Anti-diabetic doses of metformin decrease proliferation markers in tumors of patients with endometrial cancer. Gynecol Oncol 2014; 134: 607-14
-
(2014)
Gynecol Oncol
, vol.134
, pp. 607-614
-
-
Laskov, I.1
Drudi, L.2
Beauchamp, M.C.3
-
58
-
-
69549097703
-
New users of metformin are at low risk of incident cancer: A cohort study among people with type 2 diabetes
-
Libby G, Donnelly LA, Donnan PT, et al. New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes. Diabetes Care 2009; 32: 1620-5
-
(2009)
Diabetes Care
, vol.32
, pp. 1620-1625
-
-
Libby, G.1
Donnelly, L.A.2
Donnan, P.T.3
-
59
-
-
68449094325
-
The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
-
Currie CJ, Poole CD, Gale EA. The influence of glucose-lowering therapies on cancer risk in type 2 diabetes. Diabetologia 2009; 52: 1766-77
-
(2009)
Diabetologia
, vol.52
, pp. 1766-1777
-
-
Currie, C.J.1
Poole, C.D.2
Gale, E.A.3
-
60
-
-
55449124298
-
Metformin suppresses intestinal polyp growth in ApcMin/+ mice
-
Tomimoto A, Endo H, Sugiyama M, et al. Metformin suppresses intestinal polyp growth in ApcMin/+ mice. Cancer Sci 2008; 99: 2136-41
-
(2008)
Cancer Sci
, vol.99
, pp. 2136-2141
-
-
Tomimoto, A.1
Endo, H.2
Sugiyama, M.3
-
61
-
-
77954468475
-
Metformin suppresses azoxymethane-induced colorectal aberrant crypt foci by activating AMP-activated protein kinase
-
Hosono K, Endo H, Takahashi H, et al. Metformin suppresses azoxymethane-induced colorectal aberrant crypt foci by activating AMP-activated protein kinase. Mol Carcinog 2010; 49: 662-71
-
(2010)
Mol Carcinog
, vol.49
, pp. 662-671
-
-
Hosono, K.1
Endo, H.2
Takahashi, H.3
-
62
-
-
77956411030
-
Metformin suppresses colorectal aberrant crypt foci in a short-term clinical trial
-
Hosono K, Endo H, Takahashi H, et al. Metformin suppresses colorectal aberrant crypt foci in a short-term clinical trial. Cancer Prev Res (Phila) 2010; 3: 1077-83
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 1077-1083
-
-
Hosono, K.1
Endo, H.2
Takahashi, H.3
-
63
-
-
84942295218
-
Metformin-associated lactic acidosis: Predisposing factors and outcome
-
Kim MJ, Han JY, Shin JY, et al. Metformin-associated lactic acidosis: predisposing factors and outcome. Endocrinol Metab (Seoul) 2015; 30: 78-83
-
(2015)
Endocrinol Metab (Seoul)
, vol.30
, pp. 78-83
-
-
Kim, M.J.1
Han, J.Y.2
Shin, J.Y.3
-
64
-
-
0027429210
-
Metformin-an update
-
Bailey CJ. Metformin-an update. Gen Pharmacol 1993; 24: 1299-309
-
(1993)
Gen Pharmacol
, vol.24
, pp. 1299-1309
-
-
Bailey, C.J.1
-
65
-
-
0027276027
-
Metformin-associated lactic acidosis in Sweden 1977-1991
-
Wiholm BE, Myrhed M. Metformin-associated lactic acidosis in Sweden 1977-1991. Eur J Clin Pharmacol 1993; 44: 589-91
-
(1993)
Eur J Clin Pharmacol
, vol.44
, pp. 589-591
-
-
Wiholm, B.E.1
Myrhed, M.2
-
68
-
-
84886992019
-
Population pharmacokinetics of metformin in healthy subjects and patients with type 2 diabetes mellitus: Simulation of doses according to renal function
-
Duong JK, Kumar SS, Kirkpatrick CM, et al. Population pharmacokinetics of metformin in healthy subjects and patients with type 2 diabetes mellitus: simulation of doses according to renal function. Clin Pharmacokinet 2013; 52: 373-84
-
(2013)
Clin Pharmacokinet
, vol.52
, pp. 373-384
-
-
Duong, J.K.1
Kumar, S.S.2
Kirkpatrick, C.M.3
-
69
-
-
84889863920
-
Adverse effects of the common treatments for polycystic ovary syndrome: A systematic review and meta-analysis
-
Domecq JP, Prutsky G, Mullan RJ, et al. Adverse effects of the common treatments for polycystic ovary syndrome: a systematic review and meta-analysis. J Clin Endocrinol Metab 2013; 98: 4646-54
-
(2013)
J Clin Endocrinol Metab
, vol.98
, pp. 4646-4654
-
-
Domecq, J.P.1
Prutsky, G.2
Mullan, R.J.3
-
71
-
-
84860351010
-
A prospective, randomized pilot study evaluating the effects of metformin and lifestyle intervention on patients with prostate cancer receiving androgen deprivation therapy
-
Nobes JP, Langley SE, Klopper T, et al. A prospective, randomized pilot study evaluating the effects of metformin and lifestyle intervention on patients with prostate cancer receiving androgen deprivation therapy. BJU Int 2012; 109: 1495-502
-
(2012)
BJU Int
, vol.109
, pp. 1495-1502
-
-
Nobes, J.P.1
Langley, S.E.2
Klopper, T.3
-
72
-
-
0037034257
-
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
-
Knowler WC, Barrett-Connor E, Fowler SE, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002; 346: 393-403
-
(2002)
N Engl J Med
, vol.346
, pp. 393-403
-
-
Knowler, W.C.1
Barrett-Connor, E.2
Fowler, S.E.3
-
73
-
-
70449517253
-
10-year follow-up of diabetes incidence and weight loss in the diabetes prevention program outcomes study
-
Diabetes Prevention Program Research Group
-
Diabetes Prevention Program Research Group. 10-year follow-up of diabetes incidence and weight loss in the diabetes prevention program outcomes study. Lancet 2009; 374 (9702): 1677-86
-
(2009)
Lancet
, vol.374
, Issue.9702
, pp. 1677-1686
-
-
-
74
-
-
84859372038
-
Long-term safety, tolerability, and weight loss associated with metformin in the diabetes prevention program outcomes study
-
Anonymous
-
Anonymous. Long-term safety, tolerability, and weight loss associated with metformin in the diabetes prevention program outcomes study. Diabetes Care 2012; 35: 731-7
-
(2012)
Diabetes Care
, vol.35
, pp. 731-737
-
-
-
75
-
-
38849184562
-
Meta-analysis: Metformin treatment in persons at risk for diabetes mellitus
-
Salpeter SR, Buckley NS, Kahn JA, Salpeter EE. Meta-analysis: metformin treatment in persons at risk for diabetes mellitus. Am J Med 2008; 121: 149-57
-
(2008)
Am J Med
, vol.121
, pp. 149-157
-
-
Salpeter, S.R.1
Buckley, N.S.2
Kahn, J.A.3
Salpeter, E.E.4
|