-
1
-
-
0345376313
-
Treatment of diabetes mellitus with N.N. dimethyl guanil guanidine (LA 6023, glucophage)
-
Sterne J. Treatment of diabetes mellitus with N.N. dimethyl guanil guanidine (LA 6023, glucophage). Therapie. 1959;14:625-630.
-
(1959)
Therapie
, vol.14
, pp. 625-630
-
-
Sterne, J.1
-
2
-
-
0033578476
-
Pharmacologic therapy for type 2 diabetes mellitus
-
DeFronzo RA. Pharmacologic therapy for type 2 diabetes mellitus. Ann Intern Med. 1999;131:281-303
-
(1999)
Ann Intern Med
, vol.131
, pp. 281-303
-
-
DeFronzo, R.A.1
-
3
-
-
0029132285
-
Worldwide experience of metformin as an effective glucose-lowering agent: A meta-analysis
-
Campbell IW, Howlett HCS. Worldwide experience of metformin as an effective glucose-lowering agent: a meta-analysis. Diabetes Metab Rev. 1995;11 (suppl 1):S57-S62.
-
(1995)
Diabetes Metab Rev
, vol.11
, Issue.SUPPL. 1
-
-
Campbell, I.W.1
Howlett, H.C.S.2
-
4
-
-
0030881560
-
Treatment of non-insulin-dependent diabetes mellitus with metformin
-
Guthrie R. Treatment of non-insulin-dependent diabetes mellitus with metformin. J Am Board Fam Pract. 1997;10:213-221.
-
(1997)
J Am Board Fam Pract
, vol.10
, pp. 213-221
-
-
Guthrie, R.1
-
5
-
-
0032929173
-
Efficacy of metformin in the treatment of NIDDM: Meta-analysis
-
Johansen K. Efficacy of metformin in the treatment of NIDDM: meta-analysis. Diabetes Care. 1999;22:33-37.
-
(1999)
Diabetes Care
, vol.22
, pp. 33-37
-
-
Johansen, K.1
-
6
-
-
0032511566
-
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
-
UK Prospective Diabetes Study (UKPDS) Group. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet. 1998;352:854-865.
-
(1998)
Lancet
, vol.352
, pp. 854-865
-
-
-
7
-
-
0014733538
-
Lactic acidosis
-
Oliva PB. Lactic acidosis. Am J Med. 1970;48:209-225.
-
(1970)
Am J Med
, vol.48
, pp. 209-225
-
-
Oliva, P.B.1
-
8
-
-
0018843671
-
Lactate homeostasis and lactic acidosis
-
Kreisberg RA. Lactate homeostasis and lactic acidosis. Ann Intern Med. 1980;92(pt 1):227-237.
-
(1980)
Ann Intern Med
, vol.92
, Issue.PART 1
, pp. 227-237
-
-
Kreisberg, R.A.1
-
10
-
-
0029819936
-
Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus
-
Cusi K, Consoli A, DeFronzo RA. Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab. 1996;81:4059-4067.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 4059-4067
-
-
Cusi, K.1
Consoli, A.2
DeFronzo, R.A.3
-
11
-
-
0031007415
-
Contraindications to metformin therapy in patients with NIDDM
-
Sulkin TV, Bosman D, Krentz AJ. Contraindications to metformin therapy in patients with NIDDM. Diabetes Care. 1997;20:925-928.
-
(1997)
Diabetes Care
, vol.20
, pp. 925-928
-
-
Sulkin, T.V.1
Bosman, D.2
Krentz, A.J.3
-
12
-
-
0022331712
-
Metformin and the sulphonylureas: The comparative risk
-
Campbell IW. Metformin and the sulphonylureas: the comparative risk. Horm Metab Res Suppl. 1985;15:105-111.
-
(1985)
Horm Metab Res Suppl
, vol.15
, pp. 105-111
-
-
Campbell, I.W.1
-
13
-
-
0027276027
-
Metformin-associated lactic acidosis in Sweden 1977-1991
-
Wilholm BE, Myrhed M. Metformin-associated lactic acidosis in Sweden 1977-1991. Eur J Clin Pharmacol. 1993;44:589-591.
-
(1993)
Eur J Clin Pharmacol
, vol.44
, pp. 589-591
-
-
Wilholm, B.E.1
Myrhed, M.2
-
14
-
-
0032556946
-
Lactic acidosis in patients with diabetes treated with metformin
-
Misbin RI, Green L, Stadel BV, et al. Lactic acidosis in patients with diabetes treated with metformin. N Engl J Med. 1998;338:265-266.
-
(1998)
N Engl J Med
, vol.338
, pp. 265-266
-
-
Misbin, R.I.1
Green, L.2
Stadel, B.V.3
-
15
-
-
0031685819
-
Lactic acidosis rates in type 2 diabetes
-
Brown JB, Pedula K, Brassily J, et al. Lactic acidosis rates in type 2 diabetes. Diabetes Care. 1998;21:1659-1663.
-
(1998)
Diabetes Care
, vol.21
, pp. 1659-1663
-
-
Brown, J.B.1
Pedula, K.2
Brassily, J.3
-
16
-
-
84990931057
-
Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus
-
Oxford, England: Update Software
-
Salpeter S, Greyber E, Pasternak G, Salpeter E. Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus. In: The Cochrane Library [serial online]. Oxford, England: Update Software; 2002; issue 2.
-
(2002)
The Cochrane Library [Serial Online]
, Issue.2
-
-
Salpeter, S.1
Greyber, E.2
Pasternak, G.3
Salpeter, E.4
-
18
-
-
85047692188
-
Empirical evidence of bias: Dimensions of methodological quality associated with estimates of treatment effects in controlled trials
-
Schulz KF, Chalmers I, Hayes RJ, Altman DG. Empirical evidence of bias: dimensions of methodological quality associated with estimates of treatment effects in controlled trials. JAMA. 1995;273:408-412.
-
(1995)
JAMA
, vol.273
, pp. 408-412
-
-
Schulz, K.F.1
Chalmers, I.2
Hayes, R.J.3
Altman, D.G.4
-
19
-
-
0029914622
-
Assessing the quality of reports of randomized clinical trials: Is blinding necessary?
-
Jadad AR, Moore A, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials. 1996;17:1-12.
-
(1996)
Control Clin Trials
, vol.17
, pp. 1-12
-
-
Jadad, A.R.1
Moore, A.2
Carroll, D.3
-
20
-
-
0034685429
-
Meta-analysis of observational studies in epidemiology: A proposal for reporting
-
Stroup DF, Berlin JA, Morton SC, et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. JAMA. 2000;283:2008-2012.
-
(2000)
JAMA
, vol.283
, pp. 2008-2012
-
-
Stroup, D.F.1
Berlin, J.A.2
Morton, S.C.3
-
21
-
-
0031949005
-
Folate administration reduces circulating homocysteine levels in NIDDM patients on long-term metformin treatment
-
Aarsand AK, Carlsen SM. Folate administration reduces circulating homocysteine levels in NIDDM patients on long-term metformin treatment. J Intern Med. 1998;244:169-174.
-
(1998)
J Intern Med
, vol.244
, pp. 169-174
-
-
Aarsand, A.K.1
Carlsen, S.M.2
-
22
-
-
0030827537
-
Results of a placebo-controlled study of the metabolic effects of the addition of metformin to sulfonylurea-treated patients: Evidence for a central role of adipose tissue
-
Abbasi F, Kamath V, Rizvi AA, et al. Results of a placebo-controlled study of the metabolic effects of the addition of metformin to sulfonylurea-treated patients: evidence for a central role of adipose tissue. Diabetes Care. 1997;20:1863-1869.
-
(1997)
Diabetes Care
, vol.20
, pp. 1863-1869
-
-
Abbasi, F.1
Kamath, V.2
Rizvi, A.A.3
-
23
-
-
0031881129
-
Further evidence for a central role of adipose tissue in the antihyperglycemic effect of metformin
-
Abbasi F, Carantoni M, Chen YD, Reaven GM. Further evidence for a central role of adipose tissue in the antihyperglycemic effect of metformin. Diabetes Care. 1998;21:1301-1305.
-
(1998)
Diabetes Care
, vol.21
, pp. 1301-1305
-
-
Abbasi, F.1
Carantoni, M.2
Chen, Y.D.3
Reaven, G.M.4
-
24
-
-
4243613115
-
Vascular effects of glibenclamide, glimepiride, metformin and acarbose in type 2 DM patients
-
Abbink EJ, Tack CJ, Pickkers P, et al. Vascular effects of glibenclamide, glimepiride, metformin and acarbose in type 2 DM patients [abstract]. Diabetologia. 2000;43(suppl 1):A39.
-
(2000)
Diabetologia
, vol.43
, Issue.SUPPL. 1
-
-
Abbink, E.J.1
Tack, C.J.2
Pickkers, P.3
-
25
-
-
0026533094
-
Combination daytime chlorpropamide-metformin/bedtime insulin in the treatment of secondary failures in non insulin dependent diabetes
-
Aguilar CA, Wong B, Gomez-Perez FJ, Rull JA. Combination daytime chlorpropamide-metformin/bedtime insulin in the treatment of secondary failures in non insulin dependent diabetes. Rev Invest Clin. 1992;44:71-76.
-
(1992)
Rev Invest Clin
, vol.44
, pp. 71-76
-
-
Aguilar, C.A.1
Wong, B.2
Gomez-Perez, F.J.3
Rull, J.A.4
-
27
-
-
0344945006
-
Experience with biguanide treatment for diabetes mellitus
-
Andras K, Tamas H, Gyorgy K. Experience with biguanide treatment for diabetes mellitus [in Polish]. Orv Hetil. 1962;103:1029-1032.
-
(1962)
Orv Hetil
, vol.103
, pp. 1029-1032
-
-
Andras, K.1
Tamas, H.2
Gyorgy, K.3
-
28
-
-
0345425783
-
Effects of metformin in patients with poorly controlled, insulin-treated type 2 diabetes mellitus: A randomized, double-blind, placebo-controlled trial
-
Aviles-Santa L, Sinding J, Raskin P. Effects of metformin in patients with poorly controlled, insulin-treated type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial. Ann Intern Med. 1999;131:182-188.
-
(1999)
Ann Intern Med
, vol.131
, pp. 182-188
-
-
Aviles-Santa, L.1
Sinding, J.2
Raskin, P.3
-
29
-
-
0344082966
-
Treatment of diabetes with NN-dimethyl biguanide
-
Azerad E, Lasry M. Treatment of diabetes with NN-dimethyl biguanide [in French]. Gaz Med Fr. 1960;1:1555-1558.
-
(1960)
Gaz Med Fr
, vol.1
, pp. 1555-1558
-
-
Azerad, E.1
Lasry, M.2
-
30
-
-
0344514224
-
N.N. dimethyl-biguanide (DMGG) in the treatment of diabetes mellitus
-
Bacci L, Cassarini F. N.N. dimethyl-biguanide (DMGG) in the treatment of diabetes mellitus [in Italian]. Minerva Med. 1961;52:2770-2773.
-
(1961)
Minerva Med
, vol.52
, pp. 2770-2773
-
-
Bacci, L.1
Cassarini, F.2
-
31
-
-
0030070954
-
A comparison of acarbose versus metformin as an adjuvant therapy in sulfonylurea-treated NIDDM patients
-
Bayraktar M, Van Thiel DH, Adalar N. A comparison of acarbose versus metformin as an adjuvant therapy in sulfonylurea-treated NIDDM patients. Diabetes Care. 1996;19:252-254.
-
(1996)
Diabetes Care
, vol.19
, pp. 252-254
-
-
Bayraktar, M.1
Van Thiel, D.H.2
Adalar, N.3
-
32
-
-
0032939905
-
Metformin reduces systemic methylglyoxal levels in type 2 diabetes
-
Beisswenger PJ, Howell SK, Touchette AD, et al. Metformin reduces systemic methylglyoxal levels in type 2 diabetes. Diabetes. 1999;48:198-202.
-
(1999)
Diabetes
, vol.48
, pp. 198-202
-
-
Beisswenger, P.J.1
Howell, S.K.2
Touchette, A.D.3
-
33
-
-
0003156401
-
Outcome of metformin-facilitated reinitiation of oral diabetic therapy in insulin-treated patients with non-insulin-dependent diabetes mellitus
-
Bell DSH, Mayo MS. Outcome of metformin-facilitated reinitiation of oral diabetic therapy in insulin-treated patients with non-insulin-dependent diabetes mellitus. Endocr Pract. 1997;3:73-76.
-
(1997)
Endocr Pract
, vol.3
, pp. 73-76
-
-
Bell, D.S.H.1
Mayo, M.S.2
-
34
-
-
0016707304
-
Results in the treatment of diabetes with glucophage retard
-
Beyer G. Results in the treatment of diabetes with glucophage retard [in German]. TherGgw. 1975;114:1426-1437.
-
(1975)
TherGgw
, vol.114
, pp. 1426-1437
-
-
Beyer, G.1
-
35
-
-
0344082965
-
Metformin combined with chlorpropamide in the treatment of diabetes mellitus
-
Bingle JP, James JI. Metformin combined with chlorpropamide in the treatment of diabetes mellitus. Practitioner. 1964;192:567-572.
-
(1964)
Practitioner
, vol.192
, pp. 567-572
-
-
Bingle, J.P.1
James, J.I.2
-
36
-
-
0018149854
-
Influence of phenformin and metformin on exercise induced lactataemia in patients with diabetes mellitus
-
Bjorntorp P, Carlstrom S, Fagerberg SE, et al. Influence of phenformin and metformin on exercise induced lactataemia in patients with diabetes mellitus. Diabetologia. 1978;15:95-98.
-
(1978)
Diabetologia
, vol.15
, pp. 95-98
-
-
Bjorntorp, P.1
Carlstrom, S.2
Fagerberg, S.E.3
-
37
-
-
85086808707
-
Effectiveness of treatment with metformin in patients with type 2 diabetes mellitus poorly controlled with insulin treatment
-
Boronat CM, Merrero AD, La Roche BF, et al. Effectiveness of treatment with metformin in patients with type 2 diabetes mellitus poorly controlled with insulin treatment [in Spanish]. Rev Clin Esp. 2000;200:74-76.
-
(2000)
Rev Clin Esp
, vol.200
, pp. 74-76
-
-
Boronat, C.M.1
Merrero, A.D.2
La Roche, B.F.3
-
38
-
-
0017401527
-
Association of lactic acidosis with biguanide therapy
-
Botha JI, Viking AI, Jackson WP. Association of lactic acidosis with biguanide therapy [letter]. S Afr Med J. 1977;52:301-302.
-
(1977)
S Afr Med J
, vol.52
, pp. 301-302
-
-
Botha, J.I.1
Viking, A.I.2
Jackson, W.P.3
-
39
-
-
0026817052
-
Insulin, glibenclamide or metformin treatment for non insulin dependent diabetes: Heterogeneous responses of standard measures of insulin action and insulin secretion before and after differing hypoglycaemic therapy
-
Boyd K, Rogers C, Boreham C, et al. Insulin, glibenclamide or metformin treatment for non insulin dependent diabetes: heterogeneous responses of standard measures of insulin action and insulin secretion before and after differing hypoglycaemic therapy. Diabetes Res. 1992;19:69-76.
-
(1992)
Diabetes Res
, vol.19
, pp. 69-76
-
-
Boyd, K.1
Rogers, C.2
Boreham, C.3
-
40
-
-
0032740178
-
Metformin as secondary therapy in a defined population with type 2 diabetes
-
Brown JB, Pedula KL. Metformin as secondary therapy in a defined population with type 2 diabetes. Clin Ther. 1999;21:1678-1687.
-
(1999)
Clin Ther
, vol.21
, pp. 1678-1687
-
-
Brown, J.B.1
Pedula, K.L.2
-
41
-
-
0017727138
-
A comparison of phenformin and metformin in the treatment of maturity onset diabetes
-
Cairns SA, Shalet S, Marshall AJ, Hartog M. A comparison of phenformin and metformin in the treatment of maturity onset diabetes. Diabete Metab. 1977;3:183-188.
-
(1977)
Diabete Metab
, vol.3
, pp. 183-188
-
-
Cairns, S.A.1
Shalet, S.2
Marshall, A.J.3
Hartog, M.4
-
42
-
-
0028856193
-
Comparison between acarbose, metformin, and insulin treatment in type 2 diabetic patients with secondary failure to sulfonylurea treatment
-
Calle-Pascual AI, Garcia-Honduvilla J, Martin-Alvarez PJ, et al. Comparison between acarbose, metformin, and insulin treatment in type 2 diabetic patients with secondary failure to sulfonylurea treatment Diabete Metab. 1995;21:256-260.
-
(1995)
Diabete Metab
, vol.21
, pp. 256-260
-
-
Calle-Pascual, A.I.1
Garcia-Honduvilla, J.2
Martin-Alvarez, P.J.3
-
43
-
-
0141526203
-
Effects of metformin on blood pressure and microalbuminuria in diabetes mellitus
-
Campbell IW, Menzies DG, McBain AM, Brown IRF. Effects of metformin on blood pressure and microalbuminuria in diabetes mellitus. Diabete Metab. 1988;14:613-617.
-
(1988)
Diabete Metab
, vol.14
, pp. 613-617
-
-
Campbell, I.W.1
Menzies, D.G.2
McBain, A.M.3
Brown, I.R.F.4
-
44
-
-
0028605970
-
One year comparative trial of metformin and glipizide in type 2 diabetes mellitus
-
Campbell IW, Menzies DG, Chalmers J, et al. One year comparative trial of metformin and glipizide in type 2 diabetes mellitus. Diabete Metab. 1994;20:394-400.
-
(1994)
Diabete Metab
, vol.20
, pp. 394-400
-
-
Campbell, I.W.1
Menzies, D.G.2
Chalmers, J.3
-
45
-
-
0344082964
-
The treatment of diabetes mellitus: Statistical results after a review of 1190 cases
-
Canivet J, Roux P. The treatment of diabetes mellitus: statistical results after a review of 1190 cases [in French]. Presse Med. 1962;70:2038-2040.
-
(1962)
Presse Med
, vol.70
, pp. 2038-2040
-
-
Canivet, J.1
Roux, P.2
-
46
-
-
0016679871
-
Influence of metformin on arginine-induced glucagon secretion in human diabetes
-
Carpentier J, Luyckx AS, Lefebvre PJ. Influence of metformin on arginine-induced glucagon secretion in human diabetes. Diabete Metab. 1975;1:23-28.
-
(1975)
Diabete Metab
, vol.1
, pp. 23-28
-
-
Carpentier, J.1
Luyckx, A.S.2
Lefebvre, P.J.3
-
47
-
-
0024550925
-
The hyperlactatemic effect of biguanides: A comparison between phenformin and metformin during a 6-month treatment
-
Cavallo-Perin P, Aluffi E, Estivi P, et al. The hyperlactatemic effect of biguanides: a comparison between phenformin and metformin during a 6-month treatment. Riv Eur Sci Med Farmacol. 1989;11:45-49.
-
(1989)
Riv Eur Sci Med Farmacol
, vol.11
, pp. 45-49
-
-
Cavallo-Perin, P.1
Aluffi, E.2
Estivi, P.3
-
48
-
-
0001172619
-
Fibrinolytic effect of metformin in coronary-artery disease
-
Chakrabarti R, Hocking ED, Fearnley GR. Fibrinolytic effect of metformin in coronary-artery disease. Lancet. 1965;2:256-259
-
(1965)
Lancet
, vol.2
, pp. 256-259
-
-
Chakrabarti, R.1
Hocking, E.D.2
Fearnley, G.R.3
-
49
-
-
0027193068
-
Metabolic and hemodynamic effects of metformin and glibenclamide in normotensive NIDDM patients
-
Chan JC, Tomlinson B, Critchley JA, et al. Metabolic and hemodynamic effects of metformin and glibenclamide in normotensive NIDDM patients. Diabetes Care. 1993;16:1035-1038.
-
(1993)
Diabetes Care
, vol.16
, pp. 1035-1038
-
-
Chan, J.C.1
Tomlinson, B.2
Critchley, J.A.3
-
50
-
-
0027947449
-
The efficacy of acarbose in the treatment of patients with non-insulin-dependent diabetes mellitus: A multicenter controlled clinical trial
-
Chiasson J-L, Josse RG, Hunt JA, et al. The efficacy of acarbose in the treatment of patients with non-insulin-dependent diabetes mellitus: a multicenter controlled clinical trial. Ann Intern Med. 1994;121:928-935.
-
(1994)
Ann Intern Med
, vol.121
, pp. 928-935
-
-
Chiasson, J.-L.1
Josse, R.G.2
Hunt, J.A.3
-
51
-
-
0035374524
-
The synergistic effect of miglitol plus metformin combination therapy in the treatment of type 2 diabetes
-
Chiasson J-L, Naditch L. The synergistic effect of miglitol plus metformin combination therapy in the treatment of type 2 diabetes. Diabetes Care. 2001;24:989-994.
-
(2001)
Diabetes Care
, vol.24
, pp. 989-994
-
-
Chiasson, J.-L.1
Naditch, L.2
-
52
-
-
0026895212
-
Plasma t-PA and PAI-1 antigen concentrations in non-insulin dependent diabetic patients: Effects of treatment modality on fibrinolysis
-
Cho YW, Yang DH Oh DY, et al. Plasma t-PA and PAI-1 antigen concentrations in non-insulin dependent diabetic patients: effects of treatment modality on fibrinolysis. Korean J Intern Med. 1992;7:81-86.
-
(1992)
Korean J Intern Med
, vol.7
, pp. 81-86
-
-
Cho, Y.W.1
Yang, D.H.2
Oh, D.Y.3
-
53
-
-
0344082963
-
Combined metformin-chlorpropamide therapy in 108 diabetic sulphonylurea-failures
-
Clarke BF, Duncan LJP. Combined metformin-chlorpropamide therapy in 108 diabetic sulphonylurea-failures. Lancet. 1965;1:1248-1251.
-
(1965)
Lancet
, vol.1
, pp. 1248-1251
-
-
Clarke, B.F.1
Duncan, L.J.P.2
-
54
-
-
0014423575
-
Comparison of chlorpropamide and metformin treatment on weight and blood-glucose response of uncontrolled obese diabetics
-
Clarke BF, Duncan LJ. Comparison of chlorpropamide and metformin treatment on weight and blood-glucose response of uncontrolled obese diabetics. Lancet. 1968;1:123-126.
-
(1968)
Lancet
, vol.1
, pp. 123-126
-
-
Clarke, B.F.1
Duncan, L.J.2
-
55
-
-
0017754243
-
Comparison of metformin and chlorpropamide in nonobese, maturity-onset diabetics uncontrolled by diet
-
Clarke B, Campbell IW. Comparison of metformin and chlorpropamide in nonobese, maturity-onset diabetics uncontrolled by diet. BMJ. 1977;2:1576-1578.
-
(1977)
BMJ
, vol.2
, pp. 1576-1578
-
-
Clarke, B.1
Campbell, I.W.2
-
56
-
-
0024809869
-
Effect of glycaemic control, metformin and gliclazide on platelet density and aggregability in recently diagnosed type 2 (non-insulin-dependent) diabetic patients
-
Collier A, Watson HH, Patrick AW, et al. Effect of glycaemic control, metformin and gliclazide on platelet density and aggregability in recently diagnosed type 2 (non-insulin-dependent) diabetic patients. Diabete Metab. 1989;15:420-425.
-
(1989)
Diabete Metab
, vol.15
, pp. 420-425
-
-
Collier, A.1
Watson, H.H.2
Patrick, A.W.3
-
57
-
-
0030226043
-
Comparison of two treatment models in type-II diabetic patients with poor metabolic control: Preformed combination of glibenclamide 2,5 mg+metformin 400 mg or mono-therapy with sulfonylurea at maximal doses? An evaluation at six months
-
D'Argenzio R, Cavallo P, Merante D, Morelli A. Comparison of two treatment models in type-II diabetic patients with poor metabolic control: preformed combination of glibenclamide 2,5 mg+metformin 400 mg or mono-therapy with sulfonylurea at maximal doses? an evaluation at six months. Minerva Endocrinol. 1996;21:101-110.
-
(1996)
Minerva Endocrinol
, vol.21
, pp. 101-110
-
-
D'Argenzio, R.1
Cavallo, P.2
Merante, D.3
Morelli, A.4
-
58
-
-
3543004668
-
Irreversibility of the defect in glycogen syntheses activity in skeletal muscle from obese patients with NIDDM treated with diet and metformin
-
Damsbo P, Hermann LS, Vaag A, et al. Irreversibility of the defect in glycogen syntheses activity in skeletal muscle from obese patients with NIDDM treated with diet and metformin. Diabetes Care. 1998;21:1489-1494.
-
(1998)
Diabetes Care
, vol.21
, pp. 1489-1494
-
-
Damsbo, P.1
Hermann, L.S.2
Vaag, A.3
-
59
-
-
4244092507
-
Effect of metformin/glyburide tablets on HBA1c in first-line treatment of type 2 diabetes
-
Davidson J, Mooradian A, Piper B. Effect of metformin/glyburide tablets on HBA1c in first-line treatment of type 2 diabetes [abstract]. Diabetologia. 2000;43 (suppl 1):A184.
-
(2000)
Diabetologia
, vol.43
, Issue.SUPPL. 1
-
-
Davidson, J.1
Mooradian, A.2
Piper, B.3
-
60
-
-
0018673428
-
Metformin and clofibrate in maturity onset diabetes mellitus: Advantages of combined treatment
-
De Silva SR, Betteridge DJ, Shawe JEH, et al. Metformin and clofibrate in maturity onset diabetes mellitus: advantages of combined treatment. Diabete Metab. 1979;5:223-229.
-
(1979)
Diabete Metab
, vol.5
, pp. 223-229
-
-
De Silva, S.R.1
Betteridge, D.J.2
Shawe, J.E.H.3
-
61
-
-
0025837055
-
Mechanism of metformin action in obese and lean noninsulin-dependent diabetic subjects
-
DeFronzo RA, Barzilai N, Simonson D. Mechanism of metformin action in obese and lean noninsulin-dependent diabetic subjects. J Clin Endocrinol Metab. 1991;73:1294-1301.
-
(1991)
J Clin Endocrinol Metab
, vol.73
, pp. 1294-1301
-
-
DeFronzo, R.A.1
Barzilai, N.2
Simonson, D.3
-
62
-
-
0029099086
-
Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus: The Multicenter Metformin Study Group
-
DeFronzo RA, Goodman AM. Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus: the Multicenter Metformin Study Group. N Engl J Med. 1995;333:541-549.
-
(1995)
N Engl J Med
, vol.333
, pp. 541-549
-
-
DeFronzo, R.A.1
Goodman, A.M.2
-
63
-
-
0017952574
-
Long range results (5 years) in the treatment of stable diabetes with low doses of clorpropamide-metformin
-
Dies H, Lozano Castaneda O, Garcia Viveros M, et al. Long range results (5 years) in the treatment of stable diabetes with low doses of clorpropamide-metformin (author's transl) [in Spanish]. Rev Invest Clin. 1978;30:131-134.
-
(1978)
Rev Invest Clin
, vol.30
, pp. 131-134
-
-
Dies, H.1
Lozano Castaneda, O.2
Garcia Viveros, M.3
-
64
-
-
0345376307
-
Dimethyldiguanide in diabetes mellitus: Report of a small trial
-
Donnelly P. Dimethyldiguanide in diabetes mellitus: report of a small trial. J Ir Med Assoc. 1960;47:142-145.
-
(1960)
J Ir Med Assoc
, vol.47
, pp. 142-145
-
-
Donnelly, P.1
-
65
-
-
0025763252
-
Double-blind evaluation of efficacy and tolerability of metformin in NIDDM
-
Dornan TI, Heller SR, Peck GM, et al. Double-blind evaluation of efficacy and tolerability of metformin in NIDDM. Diabetes Care. 1991;14:342-344.
-
(1991)
Diabetes Care
, vol.14
, pp. 342-344
-
-
Dornan, T.I.1
Heller, S.R.2
Peck, G.M.3
-
66
-
-
0025777479
-
The effects of oral hypoglycaemic drugs on serum lipids and lipoproteins in non-insulin-dependent diabetes (NIDDM)
-
Elkeles RS. The effects of oral hypoglycaemic drugs on serum lipids and lipoproteins in non-insulin-dependent diabetes (NIDDM). Diabete Metab. 1991;17(pt 2):197-200.
-
(1991)
Diabete Metab
, vol.17
, Issue.PART 2
, pp. 197-200
-
-
Elkeles, R.S.1
-
67
-
-
0033139279
-
A comparison of preconstituted, fixed combinations of low-dose glyburide plus metformin versus high-dose glyburide alone in the treatment of type 2 diabetic patients
-
Erle G, Lovise S, Stocchiero C, et al. A comparison of preconstituted, fixed combinations of low-dose glyburide plus metformin versus high-dose glyburide alone in the treatment of type 2 diabetic patients. Acta Diabetol. 1999;36:61-65.
-
(1999)
Acta Diabetol
, vol.36
, pp. 61-65
-
-
Erle, G.1
Lovise, S.2
Stocchiero, C.3
-
68
-
-
0029905092
-
Metformin's effects on glucose and lipid metabolism in patients with secondary failure to sulfonylureas
-
Fanghanel G, Sanchez-Reyes L, Trujillo C, et al. Metformin's effects on glucose and lipid metabolism in patients with secondary failure to sulfonylureas. Diabetes Care. 1996;19:1185-1189.
-
(1996)
Diabetes Care
, vol.19
, pp. 1185-1189
-
-
Fanghanel, G.1
Sanchez-Reyes, L.2
Trujillo, C.3
-
69
-
-
2442745971
-
Effects of metformin on fibrinogen levels in obese patients with type 2 diabetes
-
Fanghanel G, Silva U, Sanchez-Reyes L, et al. Effects of metformin on fibrinogen levels in obese patients with type 2 diabetes. Rev Invest Clin. 1998;50:389-394.
-
(1998)
Rev Invest Clin
, vol.50
, pp. 389-394
-
-
Fanghanel, G.1
Silva, U.2
Sanchez-Reyes, L.3
-
70
-
-
0023916412
-
Impaired β-cell responses improve when fasting blood glucose concentration is reduced in non-insulin-dependent diabetes
-
Ferner RE, Rawlins MD, Alberti KG. Impaired β-cell responses improve when fasting blood glucose concentration is reduced in non-insulin-dependent diabetes. Q J Med. 1988;66:137-146.
-
(1988)
Q J Med
, vol.66
, pp. 137-146
-
-
Ferner, R.E.1
Rawlins, M.D.2
Alberti, K.G.3
-
71
-
-
0035138728
-
Oral antidiabetic treatment in patients with coronary disease: Time-related increased mortality on combined glyburide/metformin therapy over a 7.7-year follow-up
-
Fisman EZ, Tennenbaum A, Boyko V, et al. Oral antidiabetic treatment in patients with coronary disease: time-related increased mortality on combined glyburide/metformin therapy over a 7.7-year follow-up. Clin Cardiol. 2001;24:151-158.
-
(2001)
Clin Cardiol
, vol.24
, pp. 151-158
-
-
Fisman, E.Z.1
Tennenbaum, A.2
Boyko, V.3
-
72
-
-
0034607438
-
Effect of metformin and rosiglitazone combination therapy in patients with type 2 diabetes mellitus: A randomized controlled trial
-
Fonseca V, Rosenstock J, Patwardhan R, Salzman A. Effect of metformin and rosiglitazone combination therapy in patients with type 2 diabetes mellitus: a randomized controlled trial. JAMA. 2000;283:1695-1702.
-
(2000)
JAMA
, vol.283
, pp. 1695-1702
-
-
Fonseca, V.1
Rosenstock, J.2
Patwardhan, R.3
Salzman, A.4
-
73
-
-
0034154095
-
Intensive insulin therapy combined with metformin in obese type 2 diabetic patients
-
Fritsche A, Schmulling RM, Haring HU, Stumvoll M. Intensive insulin therapy combined with metformin in obese type 2 diabetic patients. Acta Diabetol. 2000;37:13-18.
-
(2000)
Acta Diabetol
, vol.37
, pp. 13-18
-
-
Fritsche, A.1
Schmulling, R.M.2
Haring, H.U.3
Stumvoll, M.4
-
74
-
-
0032150977
-
Gliclazide and metformin combination in patients with type 2 diabetes: Preliminary data
-
Galeone F, Fiore G, Arcangeli A, Mannucci E. Gliclazide and metformin combination in patients with type 2 diabetes: preliminary data [in Italian]. Minerva Endocrinol. 1998;23:71-75.
-
(1998)
Minerva Endocrinol
, vol.23
, pp. 71-75
-
-
Galeone, F.1
Fiore, G.2
Arcangeli, A.3
Mannucci, E.4
-
75
-
-
0031472452
-
Efficacy of metformin in type II diabetes: Results of a double-blind, placebo-controlled, dose-response trial
-
Garber AJ, Duncan TG, Goodman AM, et al. Efficacy of metformin in type II diabetes: results of a double-blind, placebo-controlled, dose-response trial. Am J Med. 1997;103:491-497.
-
(1997)
Am J Med
, vol.103
, pp. 491-497
-
-
Garber, A.J.1
Duncan, T.G.2
Goodman, A.M.3
-
76
-
-
18244426922
-
Chlorpropamide-metformin in obese diabetics or diabetics with side effects from sulfonylureas: 2-Year results
-
Garcia Viveros M, Prado Vega R, Rull JA, Lozano-Castaneda O. Chlorpropamide-metformin in obese diabetics or diabetics with side effects from sulfonylureas: 2-year results [in Spanish]. Prensa Med Mex. 1971;36:347-349.
-
(1971)
Prensa Med Mex
, vol.36
, pp. 347-349
-
-
Garcia Viveros, M.1
Prado Vega, R.2
Rull, J.A.3
Lozano-Castaneda, O.4
-
77
-
-
0027411979
-
Metformin for obese, insulin-treated diabetic patients: Improvement in glycaemic control and reduction of metabolic risk factors
-
Giugliano D, Quatraro A, Consoli G, et al. Metformin for obese, insulin-treated diabetic patients: improvement in glycaemic control and reduction of metabolic risk factors. Eur J Clin Pharmacol. 1993;44:107-112.
-
(1993)
Eur J Clin Pharmacol
, vol.44
, pp. 107-112
-
-
Giugliano, D.1
Quatraro, A.2
Consoli, G.3
-
78
-
-
0345376310
-
Metformin in treatment of diabetes mellitus
-
Gottlieb B. Metformin in treatment of diabetes mellitus. British Med J. 1962;5279:680-682.
-
(1962)
British Med J
, vol.5279
, pp. 680-682
-
-
Gottlieb, B.1
-
79
-
-
0025726560
-
Metformin causes a reduction in basal and post-venous occlusion plasminogen activator inhibitor-1 in type 2 diabetic patients
-
Grant PJ, Stickland MH, Booth NA, Prentice CR. Metformin causes a reduction in basal and post-venous occlusion plasminogen activator inhibitor-1 in type 2 diabetic patients. Diabet Med. 1991;8:361-365.
-
(1991)
Diabet Med
, vol.8
, pp. 361-365
-
-
Grant, P.J.1
Stickland, M.H.2
Booth, N.A.3
Prentice, C.R.4
-
80
-
-
0030022720
-
The effects of high- and medium-dose metformin therapy on cardiovascular risk factors in patients with type (I diabetes
-
Grant PJ. The effects of high- and medium-dose metformin therapy on cardiovascular risk factors in patients with type (I diabetes. Diabetes Care. 1996;19:64-66.
-
(1996)
Diabetes Care
, vol.19
, pp. 64-66
-
-
Grant, P.J.1
-
81
-
-
0031901216
-
Metformin reduces circulating factor VII concentrations in patients with type 2 diabetes mellitus
-
Grant PJ. Metformin reduces circulating factor VII concentrations in patients with type 2 diabetes mellitus. Thromb Haemost 1998;80:209-210.
-
(1998)
Thromb Haemost
, vol.80
, pp. 209-210
-
-
Grant, P.J.1
-
82
-
-
0024459304
-
Body mass index, blood lactate and therapeutic effectiveness of metformin in type II diabetes mellitus
-
Gregorio F, Ambrosi, F, Angelic F, et al. Body mass index, blood lactate and therapeutic effectiveness of metformin in type II diabetes mellitus. Medicina (Firenze), 1989:200-204.
-
(1989)
Medicina (Firenze)
, pp. 200-204
-
-
Gregorio, F.1
Ambrosi, F.2
Angelic, F.3
-
83
-
-
0025080219
-
Low dose metformin in the treatment of type II non-insulin-dependent diabetes: Clinical and metabolic evaluations
-
Gregorio F, Ambrosi F, Marchetti P, et al. Low dose metformin in the treatment of type II non-insulin-dependent diabetes: clinical and metabolic evaluations. Acta Diabetol Lat. 1990;27:139-155.
-
(1990)
Acta Diabetol Lat
, vol.27
, pp. 139-155
-
-
Gregorio, F.1
Ambrosi, F.2
Marchetti, P.3
-
84
-
-
0030789574
-
Metformin, plasma glucose and free fatty acids in type II diabetic out-patients: Results of a clinical study
-
Gregorio F, Ambrosi F, Manfrini S, et al. Metformin, plasma glucose and free fatty acids in type II diabetic out-patients: results of a clinical study. Diabetes Res Clin Pract. 1997;37:21-33.
-
(1997)
Diabetes Res Clin Pract
, vol.37
, pp. 21-33
-
-
Gregorio, F.1
Ambrosi, F.2
Manfrini, S.3
-
85
-
-
0024342099
-
Different effects of insulin and oral antidiabetic agents on glucose and energy metabolism in type 2 (non-insulin-dependent) diabetes mellitus
-
Groop L, Widen E, Franssila-Kallunki A, et al. Different effects of insulin and oral antidiabetic agents on glucose and energy metabolism in type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 1989;32:599-605.
-
(1989)
Diabetologia
, vol.32
, pp. 599-605
-
-
Groop, L.1
Widen, E.2
Franssila-Kallunki, A.3
-
86
-
-
0025863198
-
Treatment strategies for secondary sulfonylurea failure: Should we start insulin or add metformin? is there a place for intermittent insulin therapy?
-
Groop L, Widen E. Treatment strategies for secondary sulfonylurea failure: should we start insulin or add metformin? is there a place for intermittent insulin therapy? Diabete Metab. 1991;17(pt 2):218-223.
-
(1991)
Diabete Metab
, vol.17
, Issue.PART 2
, pp. 218-223
-
-
Groop, L.1
Widen, E.2
-
87
-
-
0030865685
-
Monitoring of metabolic control in patients with non-insulin-dependent diabetes mellitus on oral hypoglycaemic agents: Value of evening blood glucose determination
-
Guillausseau PJ. Monitoring of metabolic control in patients with non-insulin-dependent diabetes mellitus on oral hypoglycaemic agents: value of evening blood glucose determination. Diabet Med. 1997;14:798-802.
-
(1997)
Diabet Med
, vol.14
, pp. 798-802
-
-
Guillausseau, P.J.1
-
88
-
-
4243613114
-
The effect of metformin on insulin resistance and serum lipid profiles
-
Gursoy N, Ilcol Y, Tuncel E, et al. The effect of metformin on insulin resistance and serum lipid profiles [abstract]. Diabetologia. 2000;43(suppl 1):A150.
-
(2000)
Diabetologia
, vol.43
, Issue.SUPPL. 1
-
-
Gursoy, N.1
Ilcol, Y.2
Tuncel, E.3
-
89
-
-
0025904437
-
Oral antidiabetic combination therapy with sulphonylureas and metformin
-
Haupt E, Knick B, Koschinsky T, et al. Oral antidiabetic combination therapy with sulphonylureas and metformin. Diabete Metab. 1991;17(pt 2):224-231.
-
(1991)
Diabete Metab
, vol.17
, Issue.PART 2
, pp. 224-231
-
-
Haupt, E.1
Knick, B.2
Koschinsky, T.3
-
90
-
-
0345376308
-
Dimethyldiguanide (glucophage, LA 6023) in diabetes mellitus
-
Herman JB, Jackson WPU. Dimethyldiguanide (glucophage, LA 6023) in diabetes mellitus. S Afr Med J. 1961;35:286-288.
-
(1961)
S Afr Med J
, vol.35
, pp. 286-288
-
-
Herman, J.B.1
Jackson, W.P.U.2
-
91
-
-
0025843624
-
Comparative efficacy of mettormin and glibenclamide in patients with non-insulin-dependent diabetes mellitus
-
Hermann LS, Bitzen PO, Kjellstrom T, et al. Comparative efficacy of mettormin and glibenclamide in patients with non-insulin-dependent diabetes mellitus. Diabete Metab. 1991;17(pt 2):201-208.
-
(1991)
Diabete Metab
, vol.17
, Issue.PART 2
, pp. 201-208
-
-
Hermann, L.S.1
Bitzen, P.O.2
Kjellstrom, T.3
-
92
-
-
0025873686
-
Prospective comparative study in NIDDM patients of metformin and glibenclamide with special reference to lipid profiles
-
Hermann LS, Karlsson JE, Sjostrand A. Prospective comparative study in NIDDM patients of metformin and glibenclamide with special reference to lipid profiles. Eur J Clin Pharmacol. 1991;41:263-265.
-
(1991)
Eur J Clin Pharmacol
, vol.41
, pp. 263-265
-
-
Hermann, L.S.1
Karlsson, J.E.2
Sjostrand, A.3
-
93
-
-
0028034406
-
Antihyperglycaemic efficacy, response prediction and dose-response relations of treatment with metformin and sulphonylurea, alone and in primary combination
-
Hermann LS, Schersten B, Melander A. Antihyperglycaemic efficacy, response prediction and dose-response relations of treatment with metformin and sulphonylurea, alone and in primary combination. Diabet Med. 1994;11:953-960.
-
(1994)
Diabet Med
, vol.11
, pp. 953-960
-
-
Hermann, L.S.1
Schersten, B.2
Melander, A.3
-
94
-
-
0027935577
-
Therapeutic comparison of metformin and sulfonylurea, alone and in various combinations: A double-blind controlled study
-
Hermann LS, Schersten B, Bitzen PO, et al. Therapeutic comparison of metformin and sulfonylurea, alone and in various combinations: a double-blind controlled study. Diabetes Care. 1994;17:1100-1109.
-
(1994)
Diabetes Care
, vol.17
, pp. 1100-1109
-
-
Hermann, L.S.1
Schersten, B.2
Bitzen, P.O.3
-
95
-
-
0018662796
-
Double-blind trial of metformin in the therapy of non-ketotic diabetics
-
Higginbotham L, Martin FIR. Double-blind trial of metformin in the therapy of non-ketotic diabetics. Med J Aust. 1979;2:154-156.
-
(1979)
Med J Aust
, vol.2
, pp. 154-156
-
-
Higginbotham, L.1
Martin, F.I.R.2
-
96
-
-
0344915174
-
Metformin added to insulin therapy in poorly controlled type 2 diabetes
-
Hirsch IB. Metformin added to insulin therapy in poorly controlled type 2 diabetes [letter]. Diabetes Care. 1999;22:854.
-
(1999)
Diabetes Care
, vol.22
, pp. 854
-
-
Hirsch, I.B.1
-
97
-
-
0031460261
-
Efficacy of 24-week monotherapy with acarbose, metformin, or placebo in dietary-treated NIDDM patients: The Essen-II Study
-
Hoffmann J, Spengler M. Efficacy of 24-week monotherapy with acarbose, metformin, or placebo in dietary-treated NIDDM patients: the Essen-II Study. Am J Med. 1997;103:483-490.
-
(1997)
Am J Med
, vol.103
, pp. 483-490
-
-
Hoffmann, J.1
Spengler, M.2
-
98
-
-
0026040202
-
Effects of metformin on glucose, insulin and lipid metabolism in patients with mild hypertriglyceridaemia and non-insulin dependent diabetes by glucose tolerance test criteria
-
Hollenbeck CB, Johnston P, Varasteh BB, et al. Effects of metformin on glucose, insulin and lipid metabolism in patients with mild hypertriglyceridaemia and non-insulin dependent diabetes by glucose tolerance test criteria. Diabete Metab. 1991;17:483-489.
-
(1991)
Diabete Metab
, vol.17
, pp. 483-489
-
-
Hollenbeck, C.B.1
Johnston, P.2
Varasteh, B.B.3
-
99
-
-
0023190847
-
Sulphonylurea failure in type 2 diabetes: Treatment with a basal insulin supplement
-
Holman RR, Steemson J, Turner RC. Sulphonylurea failure in type 2 diabetes: treatment with a basal insulin supplement. Diabet Med. 1987;4:457-462.
-
(1987)
Diabet Med
, vol.4
, pp. 457-462
-
-
Holman, R.R.1
Steemson, J.2
Turner, R.C.3
-
100
-
-
0033754777
-
Nateglinide alone and in combination with metformin improves glycemic control by reducing mealtime glucose levels in type 2 diabetes
-
Horton ES, Clinkenbeard C, Gatlin M, et al. Nateglinide alone and in combination with metformin improves glycemic control by reducing mealtime glucose levels in type 2 diabetes. Diabetes Care. 2000;23:1660-1665.
-
(2000)
Diabetes Care
, vol.23
, pp. 1660-1665
-
-
Horton, E.S.1
Clinkenbeard, C.2
Gatlin, M.3
-
101
-
-
0024519649
-
Metformin improves peripheral but not hepatic insulin action in obese patients with type II diabetes
-
Hother-Nielsen O, Schmitz O, Andersen PH, et al. Metformin improves peripheral but not hepatic insulin action in obese patients with type II diabetes. Acta Endocrinol (Copenh). 1989;120:257-265.
-
(1989)
Acta Endocrinol (Copenh)
, vol.120
, pp. 257-265
-
-
Hother-Nielsen, O.1
Schmitz, O.2
Andersen, P.H.3
-
102
-
-
0031768586
-
Effect of troglitazone on microalbuminuria in patients with incipient diabetic nephropathy
-
Imano E, Kanda T, Nakatani Y, et al. Effect of troglitazone on microalbuminuria in patients with incipient diabetic nephropathy. Diabetes Care. 1998;21:2135-2139.
-
(1998)
Diabetes Care
, vol.21
, pp. 2135-2139
-
-
Imano, E.1
Kanda, T.2
Nakatani, Y.3
-
103
-
-
0032568257
-
Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus
-
Inzucchi SE, Maggs DG, Spollett GR, et al. Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus. N Engl J Med. 1998;338:867-872.
-
(1998)
N Engl J Med
, vol.338
, pp. 867-872
-
-
Inzucchi, S.E.1
Maggs, D.G.2
Spollett, G.R.3
-
104
-
-
0344945004
-
Combined oral therapy in diabetes
-
Jackson WPU. Combined oral therapy in diabetes. S Afr Med J. 1962;36:727-729.
-
(1962)
S Afr Med J
, vol.36
, pp. 727-729
-
-
Jackson, W.P.U.1
-
105
-
-
0023551820
-
Mechanism of metformin action in non-insulin-dependent diabetes
-
Jackson RA, Hawa MI, Jaspan JB, et al. Mechanism of metformin action in non-insulin-dependent diabetes. Diabetes. 1987;36:632-640.
-
(1987)
Diabetes
, vol.36
, pp. 632-640
-
-
Jackson, R.A.1
Hawa, M.I.2
Jaspan, J.B.3
-
106
-
-
0027981053
-
Effect of metformin on postprandial lipemia in patients with fairly to poorly controlled NIDDM
-
Jeppesen J, Zhou MY, Chen YDI, Reaven GM. Effect of metformin on postprandial lipemia in patients with fairly to poorly controlled NIDDM. Diabetes Care. 1994;17:1093-1099.
-
(1994)
Diabetes Care
, vol.17
, pp. 1093-1099
-
-
Jeppesen, J.1
Zhou, M.Y.2
Chen, Y.D.I.3
Reaven, G.M.4
-
107
-
-
0021739608
-
Acarbose treatment of sulfonylurea-treated non-insulin dependent diabetics: A double-blind cross-over comparison of an α-glucosidase inhibitor with metformin
-
Johansen K. Acarbose treatment of sulfonylurea-treated non-insulin dependent diabetics: a double-blind cross-over comparison of an α-glucosidase inhibitor with metformin. Diabete Metab. 1984;10:219-223.
-
(1984)
Diabete Metab
, vol.10
, pp. 219-223
-
-
Johansen, K.1
-
108
-
-
0027495982
-
The impact of metformin therapy on hepatic glucose production and skeletal muscle glycogen synthase activity in overweight type II diabetic patients
-
Johnson AB, Webster JM, Sum CF, et al. The impact of metformin therapy on hepatic glucose production and skeletal muscle glycogen synthase activity in overweight type II diabetic patients. Metabolism. 1993;42:1217-1222.
-
(1993)
Metabolism
, vol.42
, pp. 1217-1222
-
-
Johnson, A.B.1
Webster, J.M.2
Sum, C.F.3
-
109
-
-
0031689940
-
A retrospective chart review of uncontrolled use of metformin as an add-on therapy in type 2 diabetes
-
Johnson M, Krosnick A, Carson P, McDade AM, Laraway K. A retrospective chart review of uncontrolled use of metformin as an add-on therapy in type 2 diabetes. Clin Ther. 1998;20:691-698.
-
(1998)
Clin Ther
, vol.20
, pp. 691-698
-
-
Johnson, M.1
Krosnick, A.2
Carson, P.3
McDade, A.M.4
Laraway, K.5
-
110
-
-
0000543683
-
Long-term efficacy of rosiglitazone as monotherapy or in combination with metformin
-
Jones NP, Mather R, Owen S, et al. Long-term efficacy of rosiglitazone as monotherapy or in combination with metformin [abstract]. Diabetologia. 2000;43 (suppl 1):A192.
-
(2000)
Diabetologia
, vol.43
, Issue.SUPPL. 1
-
-
Jones, N.P.1
Mather, R.2
Owen, S.3
-
111
-
-
0003088727
-
Addition of rosiglitazone to metformin is effective in obese, insulin-resistant patients with type 2 diabetes
-
Jones T, Jones NP, Sautter M. Addition of rosiglitazone to metformin is effective in obese, insulin-resistant patients with type 2 diabetes [abstract]. Diabetologia. 2000;43(suppl 1):A191.
-
(2000)
Diabetologia
, vol.43
, Issue.SUPPL. 1
-
-
Jones, T.1
Jones, N.P.2
Sautter, M.3
-
112
-
-
0025313775
-
Comparison of tolbutamide and metformin in elderly diabetic patients
-
Josephkutty S, Potter JM. Comparison of tolbutamide and metformin in elderly diabetic patients. Diabet Med. 1990;7:510-514.
-
(1990)
Diabet Med
, vol.7
, pp. 510-514
-
-
Josephkutty, S.1
Potter, J.M.2
-
113
-
-
0029143428
-
Acarbose for the treatment of type II diabetes: The results of a Canadian multi-centre trial
-
Josse RG. Acarbose for the treatment of type II diabetes: the results of a Canadian multi-centre trial [published correction appears in Diabetes Res Clin Pract. 1995;29:215]. Diabetes Res Clin Pract. 1995;28(suppl):S167-S172.
-
(1995)
Diabetes Res Clin Pract
, vol.28
, Issue.SUPPL.
-
-
Josse, R.G.1
-
114
-
-
0028799977
-
-
published correction appears
-
Josse RG. Acarbose for the treatment of type II diabetes: the results of a Canadian multi-centre trial [published correction appears in Diabetes Res Clin Pract. 1995;29:215]. Diabetes Res Clin Pract. 1995;28(suppl):S167-S172.
-
(1995)
Diabetes Res Clin Pract
, vol.29
, pp. 215
-
-
-
116
-
-
0033223745
-
Troglitazone or metformin in combination with sulfonylureas for patients with type 2 diabetes?
-
Kirk JK, Pearce KA, Michielutte R, Summerson JH. Troglitazone or metformin in combination with sulfonylureas for patients with type 2 diabetes? J Fam Pract. 1999;48:879-882.
-
(1999)
J Fam Pract
, vol.48
, pp. 879-882
-
-
Kirk, J.K.1
Pearce, K.A.2
Michielutte, R.3
Summerson, J.H.4
-
117
-
-
0016640429
-
Therapy of diabetes mellitus using metformin: Clinical study on 60 patients
-
Klein W, Herrmann A. Therapy of diabetes mellitus using metformin: clinical study on 60 patients [in German]. Med Welt. 1975;26:516-519.
-
(1975)
Med Welt
, vol.26
, pp. 516-519
-
-
Klein, W.1
Herrmann, A.2
-
118
-
-
0025758263
-
Sulfonylurea-metformin-combination versus sulfonylurea-insulin-combination in secondary failures of sulfonylurea monotherapy: Results of a prospective randomized study in 50 patients
-
Klein W. Sulfonylurea-metformin-combination versus sulfonylurea-insulin-combination in secondary failures of sulfonylurea monotherapy: results of a prospective randomized study in 50 patients. Diabete Metab. 1991;17(pt 2): 235-240.
-
(1991)
Diabete Metab
, vol.17
, Issue.PART 2
, pp. 235-240
-
-
Klein, W.1
-
119
-
-
0025076621
-
Type 2 diabetes in the elderly: An assessment of metformin (metformin in the elderly)
-
Lalau JD, Vermersch A, Hary L, et al. Type 2 diabetes in the elderly: an assessment of metformin (metformin in the elderly). Int J Clin Pharmacol Ther Toxicol. 1990;28:329-332.
-
(1990)
Int J Clin Pharmacol Ther Toxicol
, vol.28
, pp. 329-332
-
-
Lalau, J.D.1
Vermersch, A.2
Hary, L.3
-
120
-
-
0025356354
-
Placebo-controlled trial of the effects of guar gum and metformin on fasting blood glucose and serum lipids in obese, type 2 diabetic patients
-
Lalor BC, Bhatnagar D, Winocour PH, et al. Placebo-controlled trial of the effects of guar gum and metformin on fasting blood glucose and serum lipids in obese, type 2 diabetic patients. Diabet Med. 1990;7:242-245.
-
(1990)
Diabet Med
, vol.7
, pp. 242-245
-
-
Lalor, B.C.1
Bhatnagar, D.2
Winocour, P.H.3
-
121
-
-
0031850851
-
Acarbose in NIDDM patients with poor control on conventional oral agents
-
Lam KSL, Tiu SC, Tsang MW, et al. Acarbose in NIDDM patients with poor control on conventional oral agents. Diabetes Care. 1998;21:1154-1158.
-
(1998)
Diabetes Care
, vol.21
, pp. 1154-1158
-
-
Lam, K.S.L.1
Tiu, S.C.2
Tsang, M.W.3
-
122
-
-
0026443171
-
Evaluation of the efficacy of metformin-glibenclamide treatment in overweight non-insulin dependent diabetics
-
Laurenti O, Bravi MC, Faldetta MC, De Mattia G. Evaluation of the efficacy of metformin-glibenclamide treatment in overweight non-insulin dependent diabetics. Clin Ter. 1992;140:259-263.
-
(1992)
Clin Ter
, vol.140
, pp. 259-263
-
-
Laurenti, O.1
Bravi, M.C.2
Faldetta, M.C.3
De Mattia, G.4
-
123
-
-
0020611467
-
Ciclazindol: An oral agent with weight reducing properties and hypoglycaemic activity
-
Lean ME, Borthwick LJ. Ciclazindol: an oral agent with weight reducing properties and hypoglycaemic activity. Eur J Clin Pharmacol. 1983;25:41-45.
-
(1983)
Eur J Clin Pharmacol
, vol.25
, pp. 41-45
-
-
Lean, M.E.1
Borthwick, L.J.2
-
124
-
-
0031614038
-
Metformin decreases food consumption and induces weight loss in subjects with obesity with type II non-insulin-dependent diabetes
-
Lee A, Morley JE. Metformin decreases food consumption and induces weight loss in subjects with obesity with type II non-insulin-dependent diabetes. Obes Res. 1998;6:47-53.
-
(1998)
Obes Res
, vol.6
, pp. 47-53
-
-
Lee, A.1
Morley, J.E.2
-
125
-
-
0020677914
-
Effect of metformin on insulin receptor binding and glycaemic control in type II diabetes
-
Lord JM, White SI, Bailey CJ, et al. Effect of metformin on insulin receptor binding and glycaemic control in type II diabetes. BMJ. 1983;286:830-831.
-
(1983)
BMJ
, vol.286
, pp. 830-831
-
-
Lord, J.M.1
White, S.I.2
Bailey, C.J.3
-
126
-
-
0030175229
-
Different effect of acute and chronic oral metformin administration on glucose and insulin response to bread and to pasta in non-insulin dependent diabetic patients
-
Lunetta M, DiMauro M. Different effect of acute and chronic oral metformin administration on glucose and insulin response to bread and to pasta in non-insulin dependent diabetic patients. Diabetes Res Clin Pract 1996;33:53-58.
-
(1996)
Diabetes Res Clin Pract
, vol.33
, pp. 53-58
-
-
Lunetta, M.1
DiMauro, M.2
-
127
-
-
0344609217
-
Causes of weight gain during insulin therapy with and without metformin in patients with type II diabetes mellitus
-
Makimattila S, Nikkila K, Yki-Jarvinen H. Causes of weight gain during insulin therapy with and without metformin in patients with type II diabetes mellitus. Diabetologia. 1999;42:406-412.
-
(1999)
Diabetologia
, vol.42
, pp. 406-412
-
-
Makimattila, S.1
Nikkila, K.2
Yki-Jarvinen, H.3
-
128
-
-
0027930816
-
Metabolic effects of metformin addition to chronic glibenclamide treatment in type 2 diabetes
-
Marena S, Tagliaferro V, Montegrosso G, et al. Metabolic effects of metformin addition to chronic glibenclamide treatment in type 2 diabetes. Diabete Metab. 1994;20:15-19.
-
(1994)
Diabete Metab
, vol.20
, pp. 15-19
-
-
Marena, S.1
Tagliaferro, V.2
Montegrosso, G.3
-
129
-
-
0029778182
-
Metformin improves hemodynamic and rheological responses to L-arginine in NIDDM patients
-
Marfella R, Acampora R, Verrazzo G, et al. Metformin improves hemodynamic and rheological responses to L-arginine in NIDDM patients. Diabetes Care. 1996;19:934-939.
-
(1996)
Diabetes Care
, vol.19
, pp. 934-939
-
-
Marfella, R.1
Acampora, R.2
Verrazzo, G.3
-
130
-
-
0023946973
-
A comparison of treatment with metformin and gliclazide in patients with non-insulin-dependent diabetes
-
McAlpine LG, McAlpine CH, Waclawski ER, et al. A comparison of treatment with metformin and gliclazide in patients with non-insulin-dependent diabetes. Eur J Clin Pharmacol. 1988;34:129-132.
-
(1988)
Eur J Clin Pharmacol
, vol.34
, pp. 129-132
-
-
McAlpine, L.G.1
McAlpine, C.H.2
Waclawski, E.R.3
-
131
-
-
0023765768
-
Effects of improved glycaemic control on calcium and magnesium homeostasis in type II diabetes
-
McBain AM, Brown IR, Menzies DG, Campbell IW. Effects of improved glycaemic control on calcium and magnesium homeostasis in type II diabetes. J Clin Pathol. 1988;41:933-935.
-
(1988)
J Clin Pathol
, vol.41
, pp. 933-935
-
-
McBain, A.M.1
Brown, I.R.2
Menzies, D.G.3
Campbell, I.W.4
-
132
-
-
0026241717
-
Metformin increases insulin sensitivity and basal glucose clearance in type 2 (non-insulin dependent) diabetes mellitus
-
McIntyre HD, Ma A, Bird DM, et al. Metformin increases insulin sensitivity and basal glucose clearance in type 2 (non-insulin dependent) diabetes mellitus. Aust N Z J Med. 1991;21:714-719.
-
(1991)
Aust N Z J Med
, vol.21
, pp. 714-719
-
-
McIntyre, H.D.1
Ma, A.2
Bird, D.M.3
-
133
-
-
0344944999
-
Utility of metformin as a non-hormonal agent in the treatment of diabetes mellitus
-
Mehta MJ, Vakil BJ, Narula DV, Vakil PR. Utility of metformin as a non-hormonal agent in the treatment of diabetes mellitus. J Indian Med Assoc. 1963;40:151-155.
-
(1963)
J Indian Med Assoc
, vol.40
, pp. 151-155
-
-
Mehta, M.J.1
Vakil, B.J.2
Narula, D.V.3
Vakil, P.R.4
-
134
-
-
0024500920
-
Metformin efficacy and tolerance in obese non-insulin dependent diabetics: A comparison of two dosage schedules
-
Menzies DG, Campbell IW, McBain A, Brown IR. Metformin efficacy and tolerance in obese non-insulin dependent diabetics: a comparison of two dosage schedules. Curr Med Res Opin. 1989;11:273-278.
-
(1989)
Curr Med Res Opin
, vol.11
, pp. 273-278
-
-
Menzies, D.G.1
Campbell, I.W.2
McBain, A.3
Brown, I.R.4
-
135
-
-
0345434811
-
Effect of repaglinide addition to metformin monotherapy on glycemic control in patients with type 2 diabetes
-
Moses R, Slobodniuk R, Boyages S, et al. Effect of repaglinide addition to metformin monotherapy on glycemic control in patients with type 2 diabetes. Diabetes Care. 1999;22:119-124.
-
(1999)
Diabetes Care
, vol.22
, pp. 119-124
-
-
Moses, R.1
Slobodniuk, R.2
Boyages, S.3
-
136
-
-
0016857645
-
Treatment of obese diabetic patients using glucophage retard
-
Munk W. Treatment of obese diabetic patients using glucophage retard [in German]. Z Allgemeinmed. 1975;51:681-683.
-
(1975)
Z Allgemeinmed
, vol.51
, pp. 681-683
-
-
Munk, W.1
-
137
-
-
0027399661
-
Effects of metformin on insulin resistance, risk factors for cardiovascular disease, and plasminogen activator inhibitor in NIDDM subjects: A study of two ethnic groups
-
Nagi DK, Yudkin JS. Effects of metformin on insulin resistance, risk factors for cardiovascular disease, and plasminogen activator inhibitor in NIDDM subjects: a study of two ethnic groups. Diabetes Care. 1993;16:621-629.
-
(1993)
Diabetes Care
, vol.16
, pp. 621-629
-
-
Nagi, D.K.1
Yudkin, J.S.2
-
138
-
-
0017619802
-
Comparative effects of phenformin, metformin and glibenclamide on metabolic rhythms in maturity-onset diabetics
-
Nattrass M, Todd PG, Hinks L, et al. Comparative effects of phenformin, metformin and glibenclamide on metabolic rhythms in maturity-onset diabetics. Diabetologia. 1977;13:145-152.
-
(1977)
Diabetologia
, vol.13
, pp. 145-152
-
-
Nattrass, M.1
Todd, P.G.2
Hinks, L.3
-
139
-
-
0032196235
-
Comparison of bedtime NPH insulin or metformin combined with glibenclamide in secondary sulphonylurea failure in obese type II (NIDDM) patients
-
Niazi R, Muzaffar Z. Comparison of bedtime NPH insulin or metformin combined with glibenclamide in secondary sulphonylurea failure in obese type II (NIDDM) patients. J Pak Med Assoc. 1998;48:336-338.
-
(1998)
J Pak Med Assoc
, vol.48
, pp. 336-338
-
-
Niazi, R.1
Muzaffar, Z.2
-
140
-
-
0023275154
-
Effect of metformin on insulin-stimulated glucose turnover and insulin binding to receptors in type 2 diabetes
-
Nosadini R, Avogaro A, Trevisan R, et al. Effect of metformin on insulin-stimulated glucose turnover and insulin binding to receptors in type 2 diabetes. Diabetes Care. 1987;10:62-67.
-
(1987)
Diabetes Care
, vol.10
, pp. 62-67
-
-
Nosadini, R.1
Avogaro, A.2
Trevisan, R.3
-
141
-
-
0025903612
-
Comparative three-month study of the efficacies of metformin and gliclazide in the treatment of NIDD
-
Noury J, Nandeuil A. Comparative three-month study of the efficacies of metformin and gliclazide in the treatment of NIDD. Diabete Metab. 1991;17(pt 2): 209-212.
-
(1991)
Diabete Metab
, vol.17
, Issue.PART 2
, pp. 209-212
-
-
Noury, J.1
Nandeuil, A.2
-
142
-
-
0020590982
-
The influence of dimethylbiguanide on phenprocoumon elimination and its mode of action: A drug interaction study
-
Ohnhaus EE, Berger W, Duckert F, Oesch F. The influence of dimethylbiguanide on phenprocoumon elimination and its mode of action: a drug interaction study. Kiln Wochenschr. 1983;61:851-858.
-
(1983)
Kiln Wochenschr
, vol.61
, pp. 851-858
-
-
Ohnhaus, E.E.1
Berger, W.2
Duckert, F.3
Oesch, F.4
-
143
-
-
0021237694
-
The difficult choice of treatment for poorly controlled maturity onset diabetes: Tablets or insulin?
-
Peacock I, Tattersall RB. The difficult choice of treatment for poorly controlled maturity onset diabetes: tablets or insulin? BMJ. 1984;288:1956-1959.
-
(1984)
BMJ
, vol.288
, pp. 1956-1959
-
-
Peacock, I.1
Tattersall, R.B.2
-
144
-
-
0022446692
-
Platelet behaviour in non-insulin-dependent diabetes: Influence of vascular complications, treatment and metabolic control
-
Peacock I, Hawkins M, Heptinstall S. Platelet behaviour in non-insulin-dependent diabetes: influence of vascular complications, treatment and metabolic control. Thromb Haemost. 1986;55:361-365.
-
(1986)
Thromb Haemost
, vol.55
, pp. 361-365
-
-
Peacock, I.1
Hawkins, M.2
Heptinstall, S.3
-
145
-
-
0345376303
-
The effect of metformin on weight loss in obesity
-
Pedersen J. The effect of metformin on weight loss in obesity. Acta Endocrinol. 1965;49:479-486.
-
(1965)
Acta Endocrinol
, vol.49
, pp. 479-486
-
-
Pedersen, J.1
-
146
-
-
0024574110
-
The effects of metformin on adipocyte insulin action and metabolic control in obese subjects with type 2 diabetes
-
Pedersen O, Nielsen O, Bak J, et al. The effects of metformin on adipocyte insulin action and metabolic control in obese subjects with type 2 diabetes. Diabet Med. 1989;6:249-256.
-
(1989)
Diabet Med
, vol.6
, pp. 249-256
-
-
Pedersen, O.1
Nielsen, O.2
Bak, J.3
-
147
-
-
0344945000
-
A new oral antidiabetic medicine: NN dimethylbiguanide: Clinical trial alternating a placebo with a sulfamide
-
Pirart J, Rutman S. A new oral antidiabetic medicine: NN dimethylbiguanide: clinical trial alternating a placebo with a sulfamide [in French]. Acta Clin Belg. 1961;16:575-589.
-
(1961)
Acta Clin Belg
, vol.16
, pp. 575-589
-
-
Pirart, J.1
Rutman, S.2
-
148
-
-
0033946189
-
Combined metformin and insulin therapy for patients with type 2 diabetes mellitus
-
Ponssen HH, Elte JW, Lehert P, et al. Combined metformin and insulin therapy for patients with type 2 diabetes mellitus. Clin Ther. 2000;22:709-718.
-
(2000)
Clin Ther
, vol.22
, pp. 709-718
-
-
Ponssen, H.H.1
Elte, J.W.2
Lehert, P.3
-
149
-
-
0022881373
-
Effect of metformin on peripheral insulin sensitivity in non insulin dependent diabetes mellitus
-
Prager R, Schernthaner G, Graf H. Effect of metformin on peripheral insulin sensitivity in non insulin dependent diabetes mellitus. Diabete Metab. 1986;12:346-350.
-
(1986)
Diabete Metab
, vol.12
, pp. 346-350
-
-
Prager, R.1
Schernthaner, G.2
Graf, H.3
-
150
-
-
0344082956
-
Experience with the biguanide glucophage
-
Puchegger R. Experience with the biguanide glucophage [in German]. Wien Klin Wochenschr. 1964;76:335-337.
-
(1964)
Wien Klin Wochenschr
, vol.76
, pp. 335-337
-
-
Puchegger, R.1
-
151
-
-
0023755090
-
The effect of glibenclamide and metformin on serum lipoproteins in type 2 diabetes
-
Rains SG, Wilson GA, Richmond W, Elkeles RS. The effect of glibenclamide and metformin on serum lipoproteins in type 2 diabetes. Diabet Med. 1988;5:653-658.
-
(1988)
Diabet Med
, vol.5
, pp. 653-658
-
-
Rains, S.G.1
Wilson, G.A.2
Richmond, W.3
Elkeles, R.S.4
-
152
-
-
0024490520
-
The reduction of low density lipoprotein cholesterol by metformin is maintained with long-term therapy
-
Rains SG, Wilson GA, Richmond W, Elkeles RS. The reduction of low density lipoprotein cholesterol by metformin is maintained with long-term therapy. J R Soc Med. 1989;82:93-94.
-
(1989)
J R Soc Med
, vol.82
, pp. 93-94
-
-
Rains, S.G.1
Wilson, G.A.2
Richmond, W.3
Elkeles, R.S.4
-
153
-
-
0029915090
-
Therapeutic effect of glibenclamide in a fixed combination with metformin or phenformin in NIDDM patients
-
Raptis AE, Tountas NB, Yalouris AG, et al. Therapeutic effect of glibenclamide in a fixed combination with metformin or phenformin in NIDDM patients. Horm Metab Res. 1996;28:89-94.
-
(1996)
Horm Metab Res
, vol.28
, pp. 89-94
-
-
Raptis, A.E.1
Tountas, N.B.2
Yalouris, A.G.3
-
154
-
-
0026642887
-
Combined metformin-sulfonylurea treatment of patients with noninsulin-dependent diabetes in fair to poor glycemic control
-
Reaven GM, Johnston P, Hollenbeck CB, et al. Combined metformin-sulfonylurea treatment of patients with noninsulin-dependent diabetes in fair to poor glycemic control. J Clin Endocrinol Metab. 1992;74:1020-1026.
-
(1992)
J Clin Endocrinol Metab
, vol.74
, pp. 1020-1026
-
-
Reaven, G.M.1
Johnston, P.2
Hollenbeck, C.B.3
-
155
-
-
0031793008
-
Adding metformin versus insulin dose increase in insulin-treated but poorly controlled type 2 diabetes mellitus: An open-label randomized trial
-
Relimpio F, Pumar A, Losada F, et al. Adding metformin versus insulin dose increase in insulin-treated but poorly controlled type 2 diabetes mellitus: an open-label randomized trial. Diabet Med. 1998;15:997-1002.
-
(1998)
Diabet Med
, vol.15
, pp. 997-1002
-
-
Relimpio, F.1
Pumar, A.2
Losada, F.3
-
156
-
-
0014567985
-
Chlorpropamide-dimethylbiguanide combination in the control of diabetes mellitus with complications
-
Reyes Larrasilla JM. Chlorpropamide-dimethylbiguanide combination in the control of diabetes mellitus with complications [in Spanish]. Prensa Med Mex. 1969;34:378-381.
-
(1969)
Prensa Med Mex
, vol.34
, pp. 378-381
-
-
Reyes Larrasilla, J.M.1
-
157
-
-
0025907205
-
Glucose and lipid metabolism in non-insulin-dependent diabetes: Effect of metformin
-
Riccio A, Del Prato S, Vigili DE, et al. Glucose and lipid metabolism in non-insulin-dependent diabetes: effect of metformin. Diabete Metab. 1991;17(pt 2): 180-184.
-
(1991)
Diabete Metab
, vol.17
, Issue.PART 2
, pp. 180-184
-
-
Riccio, A.1
Del Prato, S.2
Vigili, D.E.3
-
158
-
-
0031767174
-
The effects of metformin on glycemic control and serum lipids in insulin-treated NIDDM patients with suboptimal metabolic control
-
Robinson AC, Burke J, Robinson S, et al. The effects of metformin on glycemic control and serum lipids in insulin-treated NIDDM patients with suboptimal metabolic control. Diabetes Care. 1998;21:701-705.
-
(1998)
Diabetes Care
, vol.21
, pp. 701-705
-
-
Robinson, A.C.1
Burke, J.2
Robinson, S.3
-
159
-
-
0042178103
-
Clinical experience with acarbose: Results of a Canadian multicentre study
-
Rodger NW, Chiasson JL, Josse RG, et al. Clinical experience with acarbose: results of a Canadian multicentre study. Clin Invest Med. 1995;18:318-324.
-
(1995)
Clin Invest Med
, vol.18
, pp. 318-324
-
-
Rodger, N.W.1
Chiasson, J.L.2
Josse, R.G.3
-
160
-
-
0032990785
-
Addition of benfluorex to biguanide improves glycemic control in obese non-insulin-dependent diabetes: A double-blind study versus placebo
-
Roger P, Auclair J, Drain P. Addition of benfluorex to biguanide improves glycemic control in obese non-insulin-dependent diabetes: a double-blind study versus placebo. J Diabetes Complications. 1999;13:62-67.
-
(1999)
J Diabetes Complications
, vol.13
, pp. 62-67
-
-
Roger, P.1
Auclair, J.2
Drain, P.3
-
161
-
-
0031765720
-
Efficacy and safety of acarbose in metformin-treated patients with type 2 diabetes
-
Rosenstock J, Brown A, Fischer J, et al. Efficacy and safety of acarbose in metformin-treated patients with type 2 diabetes. Diabetes Care. 1998;21:2050-2055.
-
(1998)
Diabetes Care
, vol.21
, pp. 2050-2055
-
-
Rosenstock, J.1
Brown, A.2
Fischer, J.3
-
163
-
-
0028801124
-
Changes in insulin receptor tyrosine kinase activity associated with metformin treatment of type 2 diabetes
-
Santos RF, Nomizo R, Wajhenberg BL, et al. Changes in insulin receptor tyrosine kinase activity associated with metformin treatment of type 2 diabetes. Diabete Metab. 1995;21:274-280.
-
(1995)
Diabete Metab
, vol.21
, pp. 274-280
-
-
Santos, R.F.1
Nomizo, R.2
Wajhenberg, B.L.3
-
164
-
-
0025337185
-
Metformin-induced changes in serum lipids, lipoproteins, and apoproteins in non-insulin-dependent diabetes mellitus
-
Schneider J, Erren T, Zofel P, Kaffarnik H. Metformin-induced changes in serum lipids, lipoproteins, and apoproteins in non-insulin-dependent diabetes mellitus. Atherosclerosis. 1990;82:97-103.
-
(1990)
Atherosclerosis
, vol.82
, pp. 97-103
-
-
Schneider, J.1
Erren, T.2
Zofel, P.3
Kaffarnik, H.4
-
165
-
-
0015707642
-
Long-term (3 year) results of the treatment of stable diabetes with low doses of chlopropamide-metformin
-
Schulte J, Garcia Viveros M, Rull J, Lozano-Castaneda O. Long-term (3 year) results of the treatment of stable diabetes with low doses of chlopropamide-metformin [in Spanish]. Prensa Med Mex. 1973;38:281-282.
-
(1973)
Prensa Med Mex
, vol.38
, pp. 281-282
-
-
Schulte, J.1
Garcia Viveros, M.2
Rull, J.3
Lozano-Castaneda, O.4
-
166
-
-
0032606845
-
Assessment of efficacy and safety of acarbose in the treatment of diabetes mellitus: Observation study in the conditions of general health care
-
Siedradzki J, Soszynski P. Assessment of efficacy and safety of acarbose in the treatment of diabetes mellitus: observation study in the conditions of general health care. Przegl Lek. 1999;56:335-341.
-
(1999)
Przegl Lek
, vol.56
, pp. 335-341
-
-
Siedradzki, J.1
Soszynski, P.2
-
167
-
-
0034159977
-
Effect of metformin on glycaemic control in type 2 diabetes in daily practice: A retrospective study
-
Stades AM, Heikens JT, Holleman F, Hoekstra JB. Effect of metformin on glycaemic control in type 2 diabetes in daily practice: a retrospective study. Neth J Med. 2000;56:86-90.
-
(2000)
Neth J Med
, vol.56
, pp. 86-90
-
-
Stades, A.M.1
Heikens, J.T.2
Holleman, F.3
Hoekstra, J.B.4
-
168
-
-
0026008022
-
Metabolic control in diabetic subjects in three Swedish areas with high, medium and low sales of antidiabetic drugs
-
Stalhammer J, Bergman U, Boman K, Dahlen M. Metabolic control in diabetic subjects in three Swedish areas with high, medium and low sales of antidiabetic drugs. Diabetes Care. 1991;14:12-19.
-
(1991)
Diabetes Care
, vol.14
, pp. 12-19
-
-
Stalhammer, J.1
Bergman, U.2
Boman, K.3
Dahlen, M.4
-
169
-
-
0344514220
-
Report on five years experience with metformin
-
Sterne J. Report on five years experience with metformin [in German] Wien Med Wochenschr. 1963;113:599-602.
-
(1963)
Wien Med Wochenschr
, vol.113
, pp. 599-602
-
-
Sterne, J.1
-
170
-
-
0013842907
-
Experience with dimethylbiguanide in late failures of oral diabetes therapy
-
Stratmann FW. Experience with dimethylbiguanide in late failures of oral diabetes therapy [in German]. Med Welt. 1965;49:2743-2746.
-
(1965)
Med Welt
, vol.49
, pp. 2743-2746
-
-
Stratmann, F.W.1
-
171
-
-
0029133235
-
Metabolic effects of metformin in non-insulin-dependent diabetes mellitus
-
Stumvoll M, Nurjhan N, Perriello G, et al. Metabolic effects of metformin in non-insulin-dependent diabetes mellitus. N Engl J Med. 1995;333:550-554.
-
(1995)
N Engl J Med
, vol.333
, pp. 550-554
-
-
Stumvoll, M.1
Nurjhan, N.2
Perriello, G.3
-
172
-
-
0030985872
-
Comparative effects of glibenclamide and metformin on ambulatory blood pressure and cardiovascular reactivity in NIDDM
-
Sundaresan P, Lykos D, Daher A, et al. Comparative effects of glibenclamide and metformin on ambulatory blood pressure and cardiovascular reactivity in NIDDM. Diabetes Care. 1997;20:692-697.
-
(1997)
Diabetes Care
, vol.20
, pp. 692-697
-
-
Sundaresan, P.1
Lykos, D.2
Daher, A.3
-
173
-
-
0032918959
-
Safety and efficacy of metformin in a restricted formulary
-
Swislocki ALM, Knuu Q, Liao E, et al. Safety and efficacy of metformin in a restricted formulary. Am J Manag Care. 1999;5:62-68.
-
(1999)
Am J Manag Care
, vol.5
, pp. 62-68
-
-
Swislocki, A.L.M.1
Knuu, Q.2
Liao, E.3
-
174
-
-
0344944998
-
Combined trial of acetohexamide and two diguanide preparations
-
Szanto S. Combined trial of acetohexamide and two diguanide preparations. Ir J Med Sci. 1964;6:3-11.
-
(1964)
Ir J Med Sci
, vol.6
, pp. 3-11
-
-
Szanto, S.1
-
175
-
-
0020354048
-
A prospective study of the effect of 12 months treatment on serum lipids and apolipoproteins A-I and B in type 2 (non-insulin-dependent) diabetes
-
Taylor KG, John WG, Matthews KA, Wright AD. A prospective study of the effect of 12 months treatment on serum lipids and apolipoproteins A-I and B in type 2 (non-insulin-dependent) diabetes. Diabetologia. 1982;23:507-510.
-
(1982)
Diabetologia
, vol.23
, pp. 507-510
-
-
Taylor, K.G.1
John, W.G.2
Matthews, K.A.3
Wright, A.D.4
-
176
-
-
0028558603
-
Effects of metformin treatment on whole-body and splanchnic amino acid turnover in mild type 2 diabetes
-
Tessari P, Biolo G, Bruttomesso D, et al. Effects of metformin treatment on whole-body and splanchnic amino acid turnover in mild type 2 diabetes. J Clin Endocrinol Metab. 1994;79:1553-1560.
-
(1994)
J Clin Endocrinol Metab
, vol.79
, pp. 1553-1560
-
-
Tessari, P.1
Biolo, G.2
Bruttomesso, D.3
-
177
-
-
0032995666
-
Effects of gliclazide versus metformin on the clinical profile and lipid peroxidation markers in type 2 diabetes
-
Tessier D, Maheux P, Khalil A, Fulop T. Effects of gliclazide versus metformin on the clinical profile and lipid peroxidation markers in type 2 diabetes. Metabolism. 1999;48:897-903.
-
(1999)
Metabolism
, vol.48
, pp. 897-903
-
-
Tessier, D.1
Maheux, P.2
Khalil, A.3
Fulop, T.4
-
178
-
-
0030198355
-
Relationship between plasminogen activator inhibitor type-1 plasma levels and the lipoprotein(a) concentrations in non-insulin-dependent diabetes mellitus
-
Testa R, Bonfigli AR, Piantanelli L, et al. Relationship between plasminogen activator inhibitor type-1 plasma levels and the lipoprotein(a) concentrations in non-insulin-dependent diabetes mellitus. Diabetes Res Clin Pract. 1996;33:111-118.
-
(1996)
Diabetes Res Clin Pract
, vol.33
, pp. 111-118
-
-
Testa, R.1
Bonfigli, A.R.2
Piantanelli, L.3
-
179
-
-
0025893874
-
Prospective randomized two-years clinical study comparing additional metformin treatment with reducing diet in type 2 diabetes
-
Teupe B, Bergis K. Prospective randomized two-years clinical study comparing additional metformin treatment with reducing diet in type 2 diabetes. Diabete Metab. 1991;17(pt 2):213-217.
-
(1991)
Diabete Metab
, vol.17
, Issue.PART 2
, pp. 213-217
-
-
Teupe, B.1
Bergis, K.2
-
180
-
-
0026531989
-
Comparison of combined therapies in treatment of secondary failure to glyburide
-
Trischitta V, Italia S, Mazzarino S, et al. Comparison of combined therapies in treatment of secondary failure to glyburide. Diabetes Care. 1992;15:539-542.
-
(1992)
Diabetes Care
, vol.15
, pp. 539-542
-
-
Trischitta, V.1
Italia, S.2
Mazzarino, S.3
-
181
-
-
0032434317
-
Efficacy of combined treatments in NIDDM patients with secondary failure to sulphonylureas: Is it predictable?
-
Trischitta V, Italia S, Raimondo M, et al. Efficacy of combined treatments in NIDDM patients with secondary failure to sulphonylureas: is it predictable? J Endocrinol Invest. 1998;21:744-747.
-
(1998)
J Endocrinol Invest
, vol.21
, pp. 744-747
-
-
Trischitta, V.1
Italia, S.2
Raimondo, M.3
-
182
-
-
0029561311
-
Effects of α-glucosidase inhibitor (acarbose) combined with sulfonylurea or sulfonylurea and metformin in treatment of non-insulin-dependent diabetes mellitus
-
Vannasaeng S, Ploybutr S, Nitiyanant W, et al. Effects of α-glucosidase inhibitor (acarbose) combined with sulfonylurea or sulfonylurea and metformin in treatment of non-insulin-dependent diabetes mellitus. J Med Assoc Thai. 1995;78:578-585.
-
(1995)
J Med Assoc Thai
, vol.78
, pp. 578-585
-
-
Vannasaeng, S.1
Ploybutr, S.2
Nitiyanant, W.3
-
183
-
-
0027053312
-
Median-term (4 months) treatment with glibenclamide+metformin substituting for glibenclamide+fenformin lowers the lacticemia levels in type-2 diabetics (NIDDM)
-
Velussi M, Cernigoi AM, Viezzoli L, Caffau C. Median-term (4 months) treatment with glibenclamide+metformin substituting for glibenclamide+fenformin lowers the lacticemia levels in type-2 diabetics (NIDDM) [in Italian]. Clin Ter. 1992;141:483-492.
-
(1992)
Clin Ter
, vol.141
, pp. 483-492
-
-
Velussi, M.1
Cernigoi, A.M.2
Viezzoli, L.3
Caffau, C.4
-
184
-
-
0025818624
-
Treatment of NIDDM patients with secondary failure to glyburide: Comparison of the addition of either metformin or bed-time NPH insulin to glyburide
-
Vigneri R, Trischitta V, Italia S, et al. Treatment of NIDDM patients with secondary failure to glyburide: comparison of the addition of either metformin or bed-time NPH insulin to glyburide. Diabete Metab. 1991;17(pt 2):232-234.
-
(1991)
Diabete Metab
, vol.17
, Issue.PART 2
, pp. 232-234
-
-
Vigneri, R.1
Trischitta, V.2
Italia, S.3
-
185
-
-
0026549721
-
The effects of dexfenfluramine on blood glucose control in patients with type 2 diabetes
-
Willey KA, Moyneaux JE, Overland JE, Yue DK. The effects of dexfenfluramine on blood glucose control in patients with type 2 diabetes. Diabet Med. 1992;9:341-343.
-
(1992)
Diabet Med
, vol.9
, pp. 341-343
-
-
Willey, K.A.1
Moyneaux, J.E.2
Overland, J.E.3
Yue, D.K.4
-
186
-
-
0028145551
-
Obese patients with type 2 diabetes poorly controlled by insulin and metformin: Effects of adjunctive dexfenfluramine therapy on glycaemic control
-
Willey KA, Molyneaux LM, Yue DK. Obese patients with type 2 diabetes poorly controlled by insulin and metformin: effects of adjunctive dexfenfluramine therapy on glycaemic control. Diabet Med. 1994;11:701-704.
-
(1994)
Diabet Med
, vol.11
, pp. 701-704
-
-
Willey, K.A.1
Molyneaux, L.M.2
Yue, D.K.3
-
187
-
-
0032885589
-
Comparison of acarbose and metformin in patients with type 2 diabetes mellitus insufficiently controlled with diet and sulphonylureas: A randomized, placebo-controlled study
-
Willms B, Ruge D. Comparison of acarbose and metformin in patients with type 2 diabetes mellitus insufficiently controlled with diet and sulphonylureas: a randomized, placebo-controlled study. Diabet Med. 1999;16:755-761.
-
(1999)
Diabet Med
, vol.16
, pp. 755-761
-
-
Willms, B.1
Ruge, D.2
-
188
-
-
0024375773
-
A comparison of metformin versus guar in combination with sulphonylureas in the treatment of non insulin dependent diabetes
-
Wilson JA, Scott MM, Gray RS. A comparison of metformin versus guar in combination with sulphonylureas in the treatment of non insulin dependent diabetes. Horm Metab Res. 1989;21:317-319.
-
(1989)
Horm Metab Res
, vol.21
, pp. 317-319
-
-
Wilson, J.A.1
Scott, M.M.2
Gray, R.S.3
-
189
-
-
0028835301
-
One-year acarbose treatment raises fasting serum acetate in diabetic patients
-
Wolever TMS, Radmard R, Chiasson JL, et al. One-year acarbose treatment raises fasting serum acetate in diabetic patients. Diabet Med. 1995;12:164-172.
-
(1995)
Diabet Med
, vol.12
, pp. 164-172
-
-
Wolever, T.M.S.1
Radmard, R.2
Chiasson, J.L.3
-
190
-
-
0033802780
-
Miglitol, an α-glucosidase inhibitor, prevents the metformin-induced fall in serum folate and vitamin B12 in subjects with type 2 diabetes
-
Wolever TMS, Assiff L, Basu T, et al. Miglitol, an α-glucosidase inhibitor, prevents the metformin-induced fall in serum folate and vitamin B12 in subjects with type 2 diabetes. Nutr Res. 2000;20:1447-1456.
-
(2000)
Nutr Res
, vol.20
, pp. 1447-1456
-
-
Wolever, T.M.S.1
Assiff, L.2
Basu, T.3
-
191
-
-
0025057564
-
Effect of metformin on carbohydrate and lipoprotein metabolism in NIDDM patients
-
Wu MS, Johnston P, Sheu WH, et al. Effect of metformin on carbohydrate and lipoprotein metabolism in NIDDM patients. Diabetes Care. 1990;13:1-8.
-
(1990)
Diabetes Care
, vol.13
, pp. 1-8
-
-
Wu, M.S.1
Johnston, P.2
Sheu, W.H.3
-
192
-
-
26144460923
-
Metformin and insulin therapy decreases glycosylated hemoglobin and insulin requirement in type 2 diabetes
-
Wulffele MG, Kooy A, Ogterop C, et al. Metformin and insulin therapy decreases glycosylated hemoglobin and insulin requirement in type 2 diabetes [abstract]. Diabetologia. 2000;43(suppl 1):A184.
-
(2000)
Diabetologia
, vol.43
, Issue.SUPPL. 1
-
-
Wulffele, M.G.1
Kooy, A.2
Ogterop, C.3
-
193
-
-
0343724362
-
Comparison of bedtime insulin regimens in patients with type 2 diabetes mellitus: A randomized, controlled trial
-
Yki-Jarvinen H, Ryysy L, Nikkila K, et al. Comparison of bedtime insulin regimens in patients with type 2 diabetes mellitus: a randomized, controlled trial. Ann Intern Med. 1999;130:389-396.
-
(1999)
Ann Intern Med
, vol.130
, pp. 389-396
-
-
Yki-Jarvinen, H.1
Ryysy, L.2
Nikkila, K.3
-
194
-
-
0033507350
-
A comparison of troglitazone and metformin on insulin requirements in euglycemic intensively insulin-treated type 2 diabetic patients
-
Yu JG, Kruszynska YT, Mulford MI, Olefsky JM. A comparison of troglitazone and metformin on insulin requirements in euglycemic intensively insulin-treated type 2 diabetic patients. Diabetes. 1999;48:2414-2421.
-
(1999)
Diabetes
, vol.48
, pp. 2414-2421
-
-
Yu, J.G.1
Kruszynska, Y.T.2
Mulford, M.I.3
Olefsky, J.M.4
-
195
-
-
0033850956
-
Therapy focused on lowering postprandial glucose, not fasting glucose, may be superior for lowering HbA1c
-
Bastyr EJ, Stuart CA, Bradows RG, et al. Therapy focused on lowering postprandial glucose, not fasting glucose, may be superior for lowering HbA1c. Diabetes Care. 2000;23:1236-1241.
-
(2000)
Diabetes Care
, vol.23
, pp. 1236-1241
-
-
Bastyr, E.J.1
Stuart, C.A.2
Bradows, R.G.3
-
196
-
-
0033851246
-
Increased intake of calcium reverses vitamin B12 malabsorption induced by metformin
-
Bauman WA, Shaw S, Jayatillike E, et al. Increased intake of calcium reverses vitamin B12 malabsorption induced by metformin. Diabetes Care. 2000;23:1227-1231.
-
(2000)
Diabetes Care
, vol.23
, pp. 1227-1231
-
-
Bauman, W.A.1
Shaw, S.2
Jayatillike, E.3
-
197
-
-
0034791788
-
Improved glycaemic control by addition of glimepiride to metformin monotherapy in type 2 diabetic patients
-
Charpentier G, Fleury F, Kabir M, et al. Improved glycaemic control by addition of glimepiride to metformin monotherapy in type 2 diabetic patients. Diabet Med. 2001;18:828-834.
-
(2001)
Diabet Med
, vol.18
, pp. 828-834
-
-
Charpentier, G.1
Fleury, F.2
Kabir, M.3
-
198
-
-
0034531195
-
Pioglitazone hydrochloride in combination with metformin in the treatment of type 2 diabetes mellitus: A randomized, placebo-controlled study
-
Einhorn D, Rendell M, Rosenzweig J, et al. Pioglitazone hydrochloride in combination with metformin in the treatment of type 2 diabetes mellitus: a randomized, placebo-controlled study. Clin Ther. 2000;22:1395-1409.
-
(2000)
Clin Ther
, vol.22
, pp. 1395-1409
-
-
Einhorn, D.1
Rendell, M.2
Rosenzweig, J.3
-
199
-
-
0036068327
-
Troglitazone but not metformin restores insulin-stimulated phosphoinositide 2-kinase activity and increases p110β, protein levels in skeletal muscle of type 2 diabetic subjects
-
Kim Y-B, Ciaraldi TP, Kong A, et al. Troglitazone but not metformin restores insulin-stimulated phosphoinositide 2-kinase activity and increases p110β, protein levels in skeletal muscle of type 2 diabetic subjects. Diabetes. 2002;51:443-448.
-
(2002)
Diabetes
, vol.51
, pp. 443-448
-
-
Kim, Y.-B.1
Ciaraldi, T.P.2
Kong, A.3
-
200
-
-
0035312620
-
Improved endothelial function with metformin in type 2 diabetes mellitus
-
Mather KJ, Verma S, Anderson TJ. Improved endothelial function with metformin in type 2 diabetes mellitus. J Am Coll Cardiol. 2001;37:1344-1350.
-
(2001)
J Am Coll Cardiol
, vol.37
, pp. 1344-1350
-
-
Mather, K.J.1
Verma, S.2
Anderson, T.J.3
-
201
-
-
0035512619
-
Effects of sibutramine in obese female subjects with type 2 diabetes and poor blood glucose control
-
Gokcel A, Karakose H, Ertorer EM, et al. Effects of sibutramine in obese female subjects with type 2 diabetes and poor blood glucose control. Diabetes Care. 2001;24:1957-1960.
-
(2001)
Diabetes Care
, vol.24
, pp. 1957-1960
-
-
Gokcel, A.1
Karakose, H.2
Ertorer, E.M.3
-
202
-
-
0035107074
-
Improved glycaemic control with miglitol in inadequately controlled type 2 diabetics
-
Standl E, Schernthaner G, Rybka J, et al. Improved glycaemic control with miglitol in inadequately controlled type 2 diabetics. Diabetes Res Clin Pract. 2001;52:205-213.
-
(2001)
Diabetes Res Clin Pract
, vol.52
, pp. 205-213
-
-
Standl, E.1
Schernthaner, G.2
Rybka, J.3
-
203
-
-
0035339878
-
The effect of a thiazolidinedione drug, troglitazone, on glycemia in patients with type 2 diabetes mellitus poorly controlled with sulfonylurea and metformin
-
Yale J-F, Valiquett TR, Ghazzi MN, et al. The effect of a thiazolidinedione drug, troglitazone, on glycemia in patients with type 2 diabetes mellitus poorly controlled with sulfonylurea and metformin. Ann Intern Med. 2001;134:737-745.
-
(2001)
Ann Intern Med
, vol.134
, pp. 737-745
-
-
Yale, J.-F.1
Valiquett, T.R.2
Ghazzi, M.N.3
-
204
-
-
0036097556
-
Regulation of glucose transport and insulin signaling by troglitazone or metformin in adipose tissue of type 2 diabetic subjects
-
Ciraldi TP, Kong APS, Chu NV, et al. Regulation of glucose transport and insulin signaling by troglitazone or metformin in adipose tissue of type 2 diabetic subjects. Diabetes. 2002;51:30-36.
-
(2002)
Diabetes
, vol.51
, pp. 30-36
-
-
Ciraldi, T.P.1
Kong, A.P.S.2
Chu, N.V.3
-
205
-
-
0033673203
-
Mechanism by which metformin reduces glucose production in type 2 diabetes
-
Hundal RS, Krssak M, Duforur S, et al. Mechanism by which metformin reduces glucose production in type 2 diabetes. Diabetes. 2000;49:2063-2069.
-
(2000)
Diabetes
, vol.49
, pp. 2063-2069
-
-
Hundal, R.S.1
Krssak, M.2
Duforur, S.3
-
206
-
-
0034321659
-
The effect of metformin on glycemic control, serum lipids and lipoproteins in diet alone and sulfonylurea-treated type 2 diabetic patients with sub-optimal metabolic control
-
Mughal MZ, Jan M, Maheri WM, Memon MY, Ali M. The effect of metformin on glycemic control, serum lipids and lipoproteins in diet alone and sulfonylurea-treated type 2 diabetic patients with sub-optimal metabolic control. J Pak Med Assoc. 2000;50:381-386.
-
(2000)
J Pak Med Assoc
, vol.50
, pp. 381-386
-
-
Mughal, M.Z.1
Jan, M.2
Maheri, W.M.3
Memon, M.Y.4
Ali, M.5
-
207
-
-
0035167387
-
Metabolic and haemodynamic effects of metformin in patients with type 2 diabetes mellitus and hypertension
-
Uehara MH, Kohlmann NEB, Zanella MT, Ferreira SRG. Metabolic and haemodynamic effects of metformin in patients with type 2 diabetes mellitus and hypertension. Diabetes Obes Metab. 2001;3:319-325.
-
(2001)
Diabetes Obes Metab
, vol.3
, pp. 319-325
-
-
Uehara, M.H.1
Kohlmann, N.E.B.2
Zanella, M.T.3
Ferreira, S.R.G.4
-
208
-
-
0034813089
-
Monotherapy with metformin: Does it improve hypoxia in type 2 diabetic patients?
-
Cosic V, Antic S, Pesic M, et al. Monotherapy with metformin: does it improve hypoxia in type 2 diabetic patients? Clin Chem Lab Med. 2001;39:818-821.
-
(2001)
Clin Chem Lab Med
, vol.39
, pp. 818-821
-
-
Cosic, V.1
Antic, S.2
Pesic, M.3
-
209
-
-
0034464263
-
The short-term effect of a switch from glibenclamide to metformin on blood pressure and microalbuminuria in patients with type 2 diabetes mellitus
-
Amador-Licona N, Guizar-Mendoza J-M, Vargas E, et al. The short-term effect of a switch from glibenclamide to metformin on blood pressure and microalbuminuria in patients with type 2 diabetes mellitus. Arch Med Res. 2000;31:571-575.
-
(2000)
Arch Med Res
, vol.31
, pp. 571-575
-
-
Amador-Licona, N.1
Guizar-Mendoza, J.-M.2
Vargas, E.3
-
210
-
-
0034332118
-
Metformin-induced lacticacidemia in patients with type 2 diabetes mellitus
-
Abbasi AA, Kasmikha R, Sotingeanu DG. Metformin-induced lacticacidemia in patients with type 2 diabetes mellitus. Endocr Pract. 2000;6:442-446.
-
(2000)
Endocr Pract
, vol.6
, pp. 442-446
-
-
Abbasi, A.A.1
Kasmikha, R.2
Sotingeanu, D.G.3
-
211
-
-
0035515324
-
The effects of metformin and diet on plasma testosterone and leptin levels in obese
-
Ozata M, Oktenli C, Bingol N, Ozdemir IC. The effects of metformin and diet on plasma testosterone and leptin levels in obese. Men. Obes Res. 2001;9:662-667.
-
(2001)
Men Obes Res
, vol.9
, pp. 662-667
-
-
Ozata, M.1
Oktenli, C.2
Bingol, N.3
Ozdemir, I.C.4
-
212
-
-
0035179630
-
Miglitol combined with metformin improves glycaemic control in type 2 diabetes
-
Van Gaal L, Maislos M, Schernthaner G, et al. Miglitol combined with metformin improves glycaemic control in type 2 diabetes. Diabetes Obes Metab. 2001;3:326-331.
-
(2001)
Diabetes Obes Metab
, vol.3
, pp. 326-331
-
-
Van Gaal, L.1
Maislos, M.2
Schernthaner, G.3
-
213
-
-
0032724997
-
Contra-indications to metformin therapy are largely disregarded
-
Holstein A, Nahrwold D, Hinze S, Egbert EH. Contra-indications to metformin therapy are largely disregarded. Diabet Med. 1999;16:692-696.
-
(1999)
Diabet Med
, vol.16
, pp. 692-696
-
-
Holstein, A.1
Nahrwold, D.2
Hinze, S.3
Egbert, E.H.4
-
214
-
-
0027054576
-
Biguanide related lactic acidosis: Incidence and risk factors
-
Aguilar C, Reza A, Garcia JE, Rull JA. Biguanide related lactic acidosis: incidence and risk factors. Arch Med Res. 1992;23:19-24.
-
(1992)
Arch Med Res
, vol.23
, pp. 19-24
-
-
Aguilar, C.1
Reza, A.2
Garcia, J.E.3
Rull, J.A.4
-
215
-
-
0018147397
-
The risk of lactic acidosis: A comparison of the 3 biguanides in treatment of diabetics
-
Irsigler K, Kritz H, Regal H, Foltin E. The risk of lactic acidosis: a comparison of the 3 biguanides in treatment of diabetics (authors' transl) [in German]. Wien Klin Wochenschr. 1978;90:332-337.
-
(1978)
Wien Klin Wochenschr
, vol.90
, pp. 332-337
-
-
Irsigler, K.1
Kritz, H.2
Regal, H.3
Foltin, E.4
-
216
-
-
0018225059
-
Effect of biguanide therapy on lactate metabolism during graded submaximal ergometric testing
-
Pilger E, Schmid P, Goebel R. Effect of biguanide therapy on lactate metabolism during graded submaximal ergometric testing. Acta Med Austriaca. 1978;5:91-95.
-
(1978)
Acta Med Austriaca
, vol.5
, pp. 91-95
-
-
Pilger, E.1
Schmid, P.2
Goebel, R.3
-
217
-
-
0028139101
-
Re-evaluation of a biguanide, metformin: Mechanism of action and tolerability
-
Sirtori CR, Pasik C. Re-evaluation of a biguanide, metformin: mechanism of action and tolerability. Pharmacol Res. 1994;30:187-228.
-
(1994)
Pharmacol Res
, vol.30
, pp. 187-228
-
-
Sirtori, C.R.1
Pasik, C.2
-
218
-
-
0029933886
-
Clinical pharmacokinetics of metformin
-
Scheen AJ. Clinical pharmacokinetics of metformin. Clin Pharmacokinet. 1996;30:359-371.
-
(1996)
Clin Pharmacokinet
, vol.30
, pp. 359-371
-
-
Scheen, A.J.1
-
219
-
-
0032185972
-
Metformin and lactic acidosis: Guilt by association [editorial]?
-
Stacpoole PW. Metformin and lactic acidosis: guilt by association [editorial]? Diabetes Care. 1998;21:1587-1588.
-
(1998)
Diabetes Care
, vol.21
, pp. 1587-1588
-
-
Stacpoole, P.W.1
-
220
-
-
0344514214
-
Study of lactic acid levels on an empty stomach in diabetic patients treated with N-N-dimethylbiguanide
-
Debry G, Anziani C, Laurent J. Study of lactic acid levels on an empty stomach in diabetic patients treated with N-N-dimethylbiguanide. Diabetes. 1964;12:239-245.
-
(1964)
Diabetes
, vol.12
, pp. 239-245
-
-
Debry, G.1
Anziani, C.2
Laurent, J.3
-
221
-
-
0020585332
-
Metformin reduces insulin requirement in type 1 (insulin-dependent) diabetes
-
Pagano G, Tagliaferro V, Carta Q, et al. Metformin reduces insulin requirement in type 1 (insulin-dependent) diabetes. Diabetologia. 1983;24:351-354.
-
(1983)
Diabetologia
, vol.24
, pp. 351-354
-
-
Pagano, G.1
Tagliaferro, V.2
Carta, Q.3
-
222
-
-
0020554203
-
Metformin normalizes insulin binding to monocytes from obese nondiabetic subjects and obese type II diabetic patients
-
Trischitta V, Gullo D, Pezzino V, Vigneri R. Metformin normalizes insulin binding to monocytes from obese nondiabetic subjects and obese type II diabetic patients. J Clin Endocrinol Metab. 1983;57:713-718.
-
(1983)
J Clin Endocrinol Metab
, vol.57
, pp. 713-718
-
-
Trischitta, V.1
Gullo, D.2
Pezzino, V.3
Vigneri, R.4
-
223
-
-
0029946976
-
Metformin treatment in NIDDM patients with mild renal impairment
-
Connolly V, Kesson CM. Metformin treatment in NIDDM patients with mild renal impairment. Postgrad Med J. 1996;72:352-354.
-
(1996)
Postgrad Med J
, vol.72
, pp. 352-354
-
-
Connolly, V.1
Kesson, C.M.2
-
224
-
-
0018140927
-
Epidemiology of adverse drug reactions to phenformin and metformin
-
Bergman U, Boman G, Wiholm BE. Epidemiology of adverse drug reactions to phenformin and metformin. BMJ. 1978;2:464-466.
-
(1978)
BMJ
, vol.2
, pp. 464-466
-
-
Bergman, U.1
Boman, G.2
Wiholm, B.E.3
-
225
-
-
0017843124
-
Lactic acidosis in biguanide-treated diabetics: A review of 330 cases
-
Luft D, Schmulling D, Eggstein M. Lactic acidosis in biguanide-treated diabetics: a review of 330 cases. Diabetologia. 1978;14:75-87.
-
(1978)
Diabetologia
, vol.14
, pp. 75-87
-
-
Luft, D.1
Schmulling, D.2
Eggstein, M.3
-
226
-
-
0026468247
-
Biguanide-associated lactic acidosis: Case report and review of the literature
-
Gan SC, Barr J, Arieff AI, Pearl RG. Biguanide-associated lactic acidosis: case report and review of the literature. Arch Intern Med. 1992;152:2333-2336.
-
(1992)
Arch Intern Med
, vol.152
, pp. 2333-2336
-
-
Gan, S.C.1
Barr, J.2
Arieff, A.I.3
Pearl, R.G.4
-
227
-
-
0027983612
-
Metformin-associated lactic acidosis in diabetic patients with acute renal failure: A critical analysis of its pathogenesis and prognosis
-
Lalau JD, Lacroix C, De Cagny B, Fournier A. Metformin-associated lactic acidosis in diabetic patients with acute renal failure: a critical analysis of its pathogenesis and prognosis. Nephrol Dial Transplant 1994;9(suppl 4):126-129.
-
(1994)
Nephrol Dial Transplant
, vol.9
, Issue.SUPPL. 4
, pp. 126-129
-
-
Lalau, J.D.1
Lacroix, C.2
De Cagny, B.3
Fournier, A.4
|