-
1
-
-
0031682742
-
The IGF family and folliculogenesis
-
E.Y. Adashi The IGF family and folliculogenesis J Reprod Immunol 39 1998 13 19
-
(1998)
J Reprod Immunol
, vol.39
, pp. 13-19
-
-
Adashi, E.Y.1
-
2
-
-
53849118108
-
Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth
-
C. Algire, M. Zakikhani, M.J. Blouin, J.H. Shuai, and M. Pollak Metformin attenuates the stimulatory effect of a high-energy diet on in vivo LLC1 carcinoma growth Endocr Relat Cancer 15 2008 833 839
-
(2008)
Endocr Relat Cancer
, vol.15
, pp. 833-839
-
-
Algire, C.1
Zakikhani, M.2
Blouin, M.J.3
Shuai, J.H.4
Pollak, M.5
-
3
-
-
65349175605
-
Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro
-
I.N. Alimova, B. Liu, Z. Fan, S.M. Edgerton, T. Dillon, and S.E. Lind Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro Cell Cycle 8 2009 909 915
-
(2009)
Cell Cycle
, vol.8
, pp. 909-915
-
-
Alimova, I.N.1
Liu, B.2
Fan, Z.3
Edgerton, S.M.4
Dillon, T.5
Lind, S.E.6
-
4
-
-
24644475793
-
Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice
-
V.N. Anisimov, L.M. Berstein, P.A. Egormin, T.S. Piskunova, I.G. Popovich, and M.A. Zabezhinski Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice Exp Gerontol 40 2005 685 693
-
(2005)
Exp Gerontol
, vol.40
, pp. 685-693
-
-
Anisimov, V.N.1
Berstein, L.M.2
Egormin, P.A.3
Piskunova, T.S.4
Popovich, I.G.5
Zabezhinski, M.A.6
-
5
-
-
25444462729
-
Metformin decelerates aging and development of mammary tumors in HER-2/neu transgenic mice
-
V.N. Anisimov, P.A. Egormin, L.M. Bershtein, M.A. Zabezhinskii, T.S. Piskunova, and I.G. Popovich Metformin decelerates aging and development of mammary tumors in HER-2/neu transgenic mice Bull Exp Biol Med 139 2005 721 723
-
(2005)
Bull Exp Biol Med
, vol.139
, pp. 721-723
-
-
Anisimov, V.N.1
Egormin, P.A.2
Bershtein, L.M.3
Zabezhinskii, M.A.4
Piskunova, T.S.5
Popovich, I.G.6
-
6
-
-
44849099894
-
The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level
-
I. Ben Sahra, K. Laurent, A. Loubat, S. Giorgetti-Peraldi, P. Colosetti, and P. Auberger The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level Oncogene 27 2008 3576 3586
-
(2008)
Oncogene
, vol.27
, pp. 3576-3586
-
-
Ben Sahra, I.1
Laurent, K.2
Loubat, A.3
Giorgetti-Peraldi, S.4
Colosetti, P.5
Auberger, P.6
-
7
-
-
34247872895
-
Characterization of insulin/IGF hybrid receptors: Contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activation
-
S. Benyoucef, K.H. Surinya, D. Hadaschik, and K. Siddle Characterization of insulin/IGF hybrid receptors: contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activation Biochem J 403 2007 603 613
-
(2007)
Biochem J
, vol.403
, pp. 603-613
-
-
Benyoucef, S.1
Surinya, K.H.2
Hadaschik, D.3
Siddle, K.4
-
8
-
-
20444371028
-
Breast cancer receptor status in smoking and diabetic patients
-
L.M. Bershtein, E.V. Tsyrlina, I.G. Kovalenko, D.A. Vasil'ev, and V.F. Semiglazov Breast cancer receptor status in smoking and diabetic patients Vopr Onkol 51 2005 187 191
-
(2005)
Vopr Onkol
, vol.51
, pp. 187-191
-
-
Bershtein, L.M.1
Tsyrlina, E.V.2
Kovalenko, I.G.3
Vasil'Ev, D.A.4
Semiglazov, V.F.5
-
9
-
-
33646073085
-
Genotoxic factors associated with the development of receptor-negative breast cancer: Potential role of the phenomenon of switching of estrogen effects
-
L.M. Berstein, E.V. Tsyrlina, T.E. Poroshina, V.V. Levina, D.A. Vasilyev, and I.G. Kovalenko Genotoxic factors associated with the development of receptor-negative breast cancer: potential role of the phenomenon of switching of estrogen effects Exp Oncol 28 2006 64 69
-
(2006)
Exp Oncol
, vol.28
, pp. 64-69
-
-
Berstein, L.M.1
Tsyrlina, E.V.2
Poroshina, T.E.3
Levina, V.V.4
Vasilyev, D.A.5
Kovalenko, I.G.6
-
10
-
-
77953539812
-
Long-term metformin use is associated with decreased risk of breast cancer
-
M. Bodmer, C. Meier, S. Krahenbuhl, S.S. Jick, and C.R. Meier Long-term metformin use is associated with decreased risk of breast cancer Diabetes Care 33 2010 1304 1308
-
(2010)
Diabetes Care
, vol.33
, pp. 1304-1308
-
-
Bodmer, M.1
Meier, C.2
Krahenbuhl, S.3
Jick, S.S.4
Meier, C.R.5
-
11
-
-
3142729250
-
Diabetes mellitus and risk of prostate cancer: A meta-analysis
-
S. Bonovas, K. Filioussi, and A. Tsantes Diabetes mellitus and risk of prostate cancer: a meta-analysis Diabetologia 47 2004 1071 1078
-
(2004)
Diabetologia
, vol.47
, pp. 1071-1078
-
-
Bonovas, S.1
Filioussi, K.2
Tsantes, A.3
-
12
-
-
33645766204
-
Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin
-
S.L. Bowker, S.R. Majumdar, P. Veugelers, and J.A. Johnson Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin Diabetes Care 29 2006 254 258
-
(2006)
Diabetes Care
, vol.29
, pp. 254-258
-
-
Bowker, S.L.1
Majumdar, S.R.2
Veugelers, P.3
Johnson, J.A.4
-
13
-
-
70749106139
-
Metformin is a potent inhibitor of endometrial cancer cell proliferation-implications for a novel treatment strategy
-
L.A. Cantrell, C. Zhou, A. Mendivil, K.M. Malloy, P.A. Gehrig, and V.L. Bae-Jump Metformin is a potent inhibitor of endometrial cancer cell proliferation-implications for a novel treatment strategy Gynecol Oncol 116 2010 92 98
-
(2010)
Gynecol Oncol
, vol.116
, pp. 92-98
-
-
Cantrell, L.A.1
Zhou, C.2
Mendivil, A.3
Malloy, K.M.4
Gehrig, P.A.5
Bae-Jump, V.L.6
-
14
-
-
0037083568
-
Weight loss in breast cancer patient management
-
R.T. Chlebowski, E. Aiello, and A. McTiernan Weight loss in breast cancer patient management J Clin Oncol 20 2002 1128 1143
-
(2002)
J Clin Oncol
, vol.20
, pp. 1128-1143
-
-
Chlebowski, R.T.1
Aiello, E.2
McTiernan, A.3
-
15
-
-
68449094325
-
The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
-
C.J. Currie, C.D. Poole, and E.A. Gale The influence of glucose-lowering therapies on cancer risk in type 2 diabetes Diabetologia 52 2009 1766 1777
-
(2009)
Diabetologia
, vol.52
, pp. 1766-1777
-
-
Currie, C.J.1
Poole, C.D.2
Gale, E.A.3
-
18
-
-
0028804071
-
M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity
-
A.T. De Souza, G.R. Hankins, M.K. Washington, T.C. Orton, and R.L. Jirtle M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity Nat Genet 11 1995 447 449
-
(1995)
Nat Genet
, vol.11
, pp. 447-449
-
-
De Souza, A.T.1
Hankins, G.R.2
Washington, M.K.3
Orton, T.C.4
Jirtle, R.L.5
-
19
-
-
75149162547
-
Metformin: An old medication of new fashion: Evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome
-
E. Diamanti-Kandarakis, C.D. Christakou, E. Kandaraki, and F.N. Economou Metformin: an old medication of new fashion: evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome Eur J Endocrinol 162 2010 193 212
-
(2010)
Eur J Endocrinol
, vol.162
, pp. 193-212
-
-
Diamanti-Kandarakis, E.1
Christakou, C.D.2
Kandaraki, E.3
Economou, F.N.4
-
20
-
-
36348950449
-
Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells
-
R.J. Dowling, M. Zakikhani, I.G. Fantus, M. Pollak, and N. Sonenberg Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells Cancer Res 67 2007 10804 10812
-
(2007)
Cancer Res
, vol.67
, pp. 10804-10812
-
-
Dowling, R.J.1
Zakikhani, M.2
Fantus, I.G.3
Pollak, M.4
Sonenberg, N.5
-
21
-
-
20444461067
-
Metformin and reduced risk of cancer in diabetic patients
-
J.M. Evans, L.A. Donnelly, A.M. Emslie-Smith, D.R. Alessi, and A.D. Morris Metformin and reduced risk of cancer in diabetic patients BMJ 330 2005 1304 1305
-
(2005)
BMJ
, vol.330
, pp. 1304-1305
-
-
Evans, J.M.1
Donnelly, L.A.2
Emslie-Smith, A.M.3
Alessi, D.R.4
Morris, A.D.5
-
22
-
-
0029017953
-
Diabetes mellitus as a risk factor for pancreatic cancer. A meta-analysis
-
J. Everhart, and D. Wright Diabetes mellitus as a risk factor for pancreatic cancer. A meta-analysis JAMA 273 1995 1605 1609
-
(1995)
JAMA
, vol.273
, pp. 1605-1609
-
-
Everhart, J.1
Wright, D.2
-
23
-
-
34249948987
-
Diabetes mellitus and risk of endometrial cancer: A meta-analysis
-
E. Friberg, N. Orsini, C.S. Mantzoros, and A. Wolk Diabetes mellitus and risk of endometrial cancer: A meta-analysis Diabetologia 50 2007 1365 1374
-
(2007)
Diabetologia
, vol.50
, pp. 1365-1374
-
-
Friberg, E.1
Orsini, N.2
Mantzoros, C.S.3
Wolk, A.4
-
24
-
-
77949703788
-
Metformin: A therapeutic opportunity in breast cancer
-
A.M. Gonzalez-Angulo, and F. Meric-Bernstam Metformin: a therapeutic opportunity in breast cancer Clin Cancer Res 16 2010 1695 1700
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1695-1700
-
-
Gonzalez-Angulo, A.M.1
Meric-Bernstam, F.2
-
25
-
-
60549102941
-
Insulin-lowering effects of metformin in women with early breast cancer
-
P.J. Goodwin, K.I. Pritchard, M. Ennis, M. Clemons, M. Graham, and I.G. Fantus Insulin-lowering effects of metformin in women with early breast cancer Clin Breast Cancer 8 2008 501 505
-
(2008)
Clin Breast Cancer
, vol.8
, pp. 501-505
-
-
Goodwin, P.J.1
Pritchard, K.I.2
Ennis, M.3
Clemons, M.4
Graham, M.5
Fantus, I.G.6
-
26
-
-
34247520866
-
Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors
-
C.A. Granville, N. Warfel, J. Tsurutani, M.C. Hollander, M. Robertson, and S.D. Fox Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors Clin Cancer Res 13 2007 2281 2289
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2281-2289
-
-
Granville, C.A.1
Warfel, N.2
Tsurutani, J.3
Hollander, M.C.4
Robertson, M.5
Fox, S.D.6
-
27
-
-
0036830256
-
Inhibitors of mTOR reverse doxorubicin resistance conferred by PTEN status in prostate cancer cells
-
V. Grunwald, L. DeGraffenried, D. Russel, W.E. Friedrichs, R.B. Ray, and M. Hidalgo Inhibitors of mTOR reverse doxorubicin resistance conferred by PTEN status in prostate cancer cells Cancer Res 62 2002 6141 6145
-
(2002)
Cancer Res
, vol.62
, pp. 6141-6145
-
-
Grunwald, V.1
Degraffenried, L.2
Russel, D.3
Friedrichs, W.E.4
Ray, R.B.5
Hidalgo, M.6
-
28
-
-
2442659101
-
Breast cancer: Biological characteristics in postmenopausal type 2 diabetic women. Identification of therapeutic targets
-
E. Guastamacchia, F. Resta, A. Mangia, F. Schittulli, A. Ciampolillo, and V. Triggiani Breast cancer: biological characteristics in postmenopausal type 2 diabetic women. Identification of therapeutic targets Curr Drug Targets Immune Endocr Metabol Disord 3 2003 205 209
-
(2003)
Curr Drug Targets Immune Endocr Metabol Disord
, vol.3
, pp. 205-209
-
-
Guastamacchia, E.1
Resta, F.2
Mangia, A.3
Schittulli, F.4
Ciampolillo, A.5
Triggiani, V.6
-
29
-
-
78149456040
-
Gene signature of metformin actions on primary breast cancer within a window of opportunity randomized clinical trial
-
S. Hadad, J. Dewar, E. Elseedawy, L. Jordan, C. Purdie, and S. Bray Gene signature of metformin actions on primary breast cancer within a window of opportunity randomized clinical trial J Clin Oncol Vol. 28 2010 560 (Suppl)
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL.
, pp. 560
-
-
Hadad, S.1
Dewar, J.2
Elseedawy, E.3
Jordan, L.4
Purdie, C.5
Bray, S.6
-
30
-
-
33748118458
-
Neither LKB1 nor AMPK are the direct targets of metformin
-
author reply 974-975.
-
D.G. Hardie Neither LKB1 nor AMPK are the direct targets of metformin Gastroenterology 131 2006 973 author reply 974-975.
-
(2006)
Gastroenterology
, vol.131
, pp. 973
-
-
Hardie, D.G.1
-
31
-
-
0036324142
-
The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism
-
S.A. Hawley, A.E. Gadalla, G.S. Olsen, and D.G. Hardie The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism Diabetes 51 2002 2420 2425
-
(2002)
Diabetes
, vol.51
, pp. 2420-2425
-
-
Hawley, S.A.1
Gadalla, A.E.2
Olsen, G.S.3
Hardie, D.G.4
-
32
-
-
4043171462
-
Upstream and downstream of mTOR
-
N. Hay, and N. Sonenberg Upstream and downstream of mTOR Genes Dev 18 2004 1926 1945
-
(2004)
Genes Dev
, vol.18
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
33
-
-
77952098898
-
Diabetes therapy and cancer risk: Causal effects and other plausible explanations
-
S. Hernandez-Diaz, and H.O. Adami Diabetes therapy and cancer risk: causal effects and other plausible explanations Diabetologia 53 2010 802 808
-
(2010)
Diabetologia
, vol.53
, pp. 802-808
-
-
Hernandez-Diaz, S.1
Adami, H.O.2
-
34
-
-
70350236538
-
Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission
-
H.A. Hirsch, D. Iliopoulos, P.N. Tsichlis, and K. Struhl Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission Cancer Res 69 2009 7507 7511
-
(2009)
Cancer Res
, vol.69
, pp. 7507-7511
-
-
Hirsch, H.A.1
Iliopoulos, D.2
Tsichlis, P.N.3
Struhl, K.4
-
35
-
-
77956411030
-
Metformin suppresses colorectal aberrant crypt foci in a short-term clinical trial
-
K. Hosono, H. Endo, H. Takahashi, M. Sugiyama, E. Sakai, and T. Uchiyama Metformin suppresses colorectal aberrant crypt foci in a short-term clinical trial Cancer Prev Res (Phila) 3 2010 1077 1083
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 1077-1083
-
-
Hosono, K.1
Endo, H.2
Takahashi, H.3
Sugiyama, M.4
Sakai, E.5
Uchiyama, T.6
-
36
-
-
77954468475
-
Metformin suppresses azoxymethane-induced colorectal aberrant crypt foci by activating AMP-activated protein kinase
-
K. Hosono, H. Endo, H. Takahashi, M. Sugiyama, T. Uchiyama, and K. Suzuki Metformin suppresses azoxymethane-induced colorectal aberrant crypt foci by activating AMP-activated protein kinase Mol Carcinog 49 2010 662 671
-
(2010)
Mol Carcinog
, vol.49
, pp. 662-671
-
-
Hosono, K.1
Endo, H.2
Takahashi, H.3
Sugiyama, M.4
Uchiyama, T.5
Suzuki, K.6
-
37
-
-
33747663672
-
Metformin treatment to prevent early puberty in girls with precocious pubarche
-
L. Ibanez, K. Ong, C. Valls, M.V. Marcos, D.B. Dunger, and F. de Zegher Metformin treatment to prevent early puberty in girls with precocious pubarche J Clin Endocrinol Metab 91 2006 2888 2891
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 2888-2891
-
-
Ibanez, L.1
Ong, K.2
Valls, C.3
Marcos, M.V.4
Dunger, D.B.5
De Zegher, F.6
-
38
-
-
11244297916
-
Dysregulation of the TSC-mTOR pathway in human disease
-
K. Inoki, M.N. Corradetti, and K.L. Guan Dysregulation of the TSC-mTOR pathway in human disease Nat Genet 37 2005 19 24
-
(2005)
Nat Genet
, vol.37
, pp. 19-24
-
-
Inoki, K.1
Corradetti, M.N.2
Guan, K.L.3
-
39
-
-
0345167800
-
TSC2 mediates cellular energy response to control cell growth and survival
-
K. Inoki, T. Zhu, and K.L. Guan TSC2 mediates cellular energy response to control cell growth and survival Cell 115 2003 577 590
-
(2003)
Cell
, vol.115
, pp. 577-590
-
-
Inoki, K.1
Zhu, T.2
Guan, K.L.3
-
40
-
-
67749144226
-
Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer
-
S. Jiralerspong, S.L. Palla, S.H. Giordano, F. Meric-Bernstam, C. Liedtke, and C.M. Barnett Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer J Clin Oncol 27 2009 3297 3302
-
(2009)
J Clin Oncol
, vol.27
, pp. 3297-3302
-
-
Jiralerspong, S.1
Palla, S.L.2
Giordano, S.H.3
Meric-Bernstam, F.4
Liedtke, C.5
Barnett, C.M.6
-
41
-
-
33845328853
-
A meta-analysis of diabetes mellitus and the risk of prostate cancer
-
J.S. Kasper, and E. Giovannucci A meta-analysis of diabetes mellitus and the risk of prostate cancer Cancer Epidemiol Biomarkers Prev 15 2006 2056 2062
-
(2006)
Cancer Epidemiol Biomarkers Prev
, vol.15
, pp. 2056-2062
-
-
Kasper, J.S.1
Giovannucci, E.2
-
42
-
-
11144355692
-
Sterol regulatory element-binding protein (SREBP)-1: Gene regulatory target for insulin resistance?
-
J. Kotzka, and D. Muller-Wieland Sterol regulatory element-binding protein (SREBP)-1: gene regulatory target for insulin resistance? Expert Opin Ther Targets 8 2004 141 149
-
(2004)
Expert Opin Ther Targets
, vol.8
, pp. 141-149
-
-
Kotzka, J.1
Muller-Wieland, D.2
-
43
-
-
75149179169
-
Metformin associated with lower cancer mortality in type 2 diabetes: ZODIAC-16
-
G.W. Landman, N. Kleefstra, K.J. van Hateren, K.H. Groenier, R.O. Gans, and H.J. Bilo Metformin associated with lower cancer mortality in type 2 diabetes: ZODIAC-16 Diabetes Care 33 2010 322 326
-
(2010)
Diabetes Care
, vol.33
, pp. 322-326
-
-
Landman, G.W.1
Kleefstra, N.2
Van Hateren, K.J.3
Groenier, K.H.4
Gans, R.O.5
Bilo, H.J.6
-
44
-
-
66149147056
-
Glycemic load, glycemic index and breast cancer risk in a prospective cohort of Swedish women
-
S.C. Larsson, L. Bergkvist, and A. Wolk Glycemic load, glycemic index and breast cancer risk in a prospective cohort of Swedish women Int J Cancer 125 2009 153 157
-
(2009)
Int J Cancer
, vol.125
, pp. 153-157
-
-
Larsson, S.C.1
Bergkvist, L.2
Wolk, A.3
-
45
-
-
34547127614
-
Diabetes mellitus and risk of breast cancer: A meta-analysis
-
S.C. Larsson, C.S. Mantzoros, and A. Wolk Diabetes mellitus and risk of breast cancer: a meta-analysis Int J Cancer 121 2007 856 862
-
(2007)
Int J Cancer
, vol.121
, pp. 856-862
-
-
Larsson, S.C.1
Mantzoros, C.S.2
Wolk, A.3
-
46
-
-
33750930105
-
Diabetes mellitus and risk of bladder cancer: A meta-analysis
-
S.C. Larsson, N. Orsini, K. Brismar, and A. Wolk Diabetes mellitus and risk of bladder cancer: a meta-analysis Diabetologia 49 2006 2819 2823
-
(2006)
Diabetologia
, vol.49
, pp. 2819-2823
-
-
Larsson, S.C.1
Orsini, N.2
Brismar, K.3
Wolk, A.4
-
47
-
-
27944450832
-
Diabetes mellitus and risk of colorectal cancer: A meta-analysis
-
S.C. Larsson, N. Orsini, and A. Wolk Diabetes mellitus and risk of colorectal cancer: a meta-analysis J Natl Cancer Inst 97 2005 1679 1687
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1679-1687
-
-
Larsson, S.C.1
Orsini, N.2
Wolk, A.3
-
48
-
-
67650945180
-
Antidiabetic therapies affect risk of pancreatic cancer
-
D. Li, S.C. Yeung, M.M. Hassan, M. Konopleva, and J.L. Abbruzzese Antidiabetic therapies affect risk of pancreatic cancer Gastroenterology 137 2009 482 488
-
(2009)
Gastroenterology
, vol.137
, pp. 482-488
-
-
Li, D.1
Yeung, S.C.2
Hassan, M.M.3
Konopleva, M.4
Abbruzzese, J.L.5
-
49
-
-
79955673061
-
Effects of metformin and rosiglitazone on peripheral insulin resistance and beta-cell function in obesity: A double-blind, randomized, controlled study
-
X. Li, N. Zhang, Y. Li, Y. Shi, D. Li, and Y. Xie Effects of metformin and rosiglitazone on peripheral insulin resistance and beta-cell function in obesity: a double-blind, randomized, controlled study J Int Med Res 39 2011 358 365
-
(2011)
J Int Med Res
, vol.39
, pp. 358-365
-
-
Li, X.1
Zhang, N.2
Li, Y.3
Shi, Y.4
Li, D.5
Xie, Y.6
-
50
-
-
69549097703
-
New users of metformin are at low risk of incident cancer: A cohort study among people with type 2 diabetes
-
G. Libby, L.A. Donnelly, P.T. Donnan, D.R. Alessi, A.D. Morris, and J.M. Evans New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes Diabetes Care 32 2009 1620 1625
-
(2009)
Diabetes Care
, vol.32
, pp. 1620-1625
-
-
Libby, G.1
Donnelly, L.A.2
Donnan, P.T.3
Alessi, D.R.4
Morris, A.D.5
Evans, J.M.6
-
51
-
-
67650514082
-
Metformin induces unique biological and molecular responses in triple negative breast cancer cells
-
B. Liu, Z. Fan, S.M. Edgerton, X.S. Deng, I.N. Alimova, and S.E. Lind Metformin induces unique biological and molecular responses in triple negative breast cancer cells Cell Cycle 8 2009 2031 2040
-
(2009)
Cell Cycle
, vol.8
, pp. 2031-2040
-
-
Liu, B.1
Fan, Z.2
Edgerton, S.M.3
Deng, X.S.4
Alimova, I.N.5
Lind, S.E.6
-
52
-
-
0142247208
-
Metformin in polycystic ovary syndrome: Systematic review and meta-analysis
-
J.M. Lord, I.H. Flight, and R.J. Norman Metformin in polycystic ovary syndrome: systematic review and meta-analysis BMJ 327 2003 951 953
-
(2003)
BMJ
, vol.327
, pp. 951-953
-
-
Lord, J.M.1
Flight, I.H.2
Norman, R.J.3
-
53
-
-
0035883890
-
Metformin in non-alcoholic steatohepatitis
-
G. Marchesini, M. Brizi, G. Bianchi, S. Tomassetti, M. Zoli, and N. Melchionda Metformin in non-alcoholic steatohepatitis Lancet 358 2001 893 894
-
(2001)
Lancet
, vol.358
, pp. 893-894
-
-
Marchesini, G.1
Brizi, M.2
Bianchi, G.3
Tomassetti, S.4
Zoli, M.5
Melchionda, N.6
-
54
-
-
77949323798
-
Incorporating the antidiabetic drug metformin in HER2-positive breast cancer treated with neo-adjuvant chemotherapy and trastuzumab: An ongoing clinical-translational research experience at the Catalan Institute of Oncology
-
B. Martin-Castillo, J. Dorca, A. Vazquez-Martin, C. Oliveras-Ferraros, E. Lopez-Bonet, and M. Garcia Incorporating the antidiabetic drug metformin in HER2-positive breast cancer treated with neo-adjuvant chemotherapy and trastuzumab: an ongoing clinical-translational research experience at the Catalan Institute of Oncology Ann Oncol 21 2010 187 189
-
(2010)
Ann Oncol
, vol.21
, pp. 187-189
-
-
Martin-Castillo, B.1
Dorca, J.2
Vazquez-Martin, A.3
Oliveras-Ferraros, C.4
Lopez-Bonet, E.5
Garcia, M.6
-
55
-
-
77956415337
-
Metformin prevents tobacco carcinogen-induced lung tumorigenesis
-
R.M. Memmott, J.R. Mercado, C.R. Maier, S. Kawabata, S.D. Fox, and P.A. Dennis Metformin prevents tobacco carcinogen-induced lung tumorigenesis Cancer Prev Res (Phila) 3 2010 1066 1076
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 1066-1076
-
-
Memmott, R.M.1
Mercado, J.R.2
Maier, C.R.3
Kawabata, S.4
Fox, S.D.5
Dennis, P.A.6
-
56
-
-
69249231052
-
Metformin, diet and breast cancer: An avenue for chemoprevention
-
P. Muti, F. Berrino, V. Krogh, A. Villarini, M. Barba, and S. Strano Metformin, diet and breast cancer: an avenue for chemoprevention Cell Cycle 8 2009 2661
-
(2009)
Cell Cycle
, vol.8
, pp. 2661
-
-
Muti, P.1
Berrino, F.2
Krogh, V.3
Villarini, A.4
Barba, M.5
Strano, S.6
-
57
-
-
79954979578
-
Clinical and biologic effects of metformin in early stage breast cancer
-
Abstract # PD03-06
-
S. Niraula, V. Stambolic, R. Dowling, M. Ennis, M. Chang, and S. Done Clinical and biologic effects of metformin in early stage breast cancer Abstract # PD03-06 Cancer Res Vol. 70 2010 24,Suppl 104S
-
(2010)
Cancer Res
, vol.70
, Issue.SUPPL. 104S
, pp. 24
-
-
Niraula, S.1
Stambolic, V.2
Dowling, R.3
Ennis, M.4
Chang, M.5
Done, S.6
-
58
-
-
33646528017
-
Metabolic syndrome as a prognostic factor for breast cancer recurrences
-
P. Pasanisi, F. Berrino, M. De Petris, E. Venturelli, A. Mastroianni, and S. Panico Metabolic syndrome as a prognostic factor for breast cancer recurrences Int J Cancer 119 2006 236 238
-
(2006)
Int J Cancer
, vol.119
, pp. 236-238
-
-
Pasanisi, P.1
Berrino, F.2
De Petris, M.3
Venturelli, E.4
Mastroianni, A.5
Panico, S.6
-
59
-
-
78149357382
-
Clinical outcomes after radical prostatectomy in diabetic patients treated with metformin
-
T. Patel, G. Hruby, K. Badani, C. Abate-Shen, and J.M. McKiernan Clinical outcomes after radical prostatectomy in diabetic patients treated with metformin Urology 76 2010 1240 1244
-
(2010)
Urology
, vol.76
, pp. 1240-1244
-
-
Patel, T.1
Hruby, G.2
Badani, K.3
Abate-Shen, C.4
McKiernan, J.M.5
-
60
-
-
9744274552
-
Effects of energy balance on cancer in genetically altered mice
-
A.C. Patel, N.P. Nunez, S.N. Perkins, J.C. Barrett, and S.D. Hursting Effects of energy balance on cancer in genetically altered mice J Nutr 134 2004 3394S 3398S
-
(2004)
J Nutr
, vol.134
-
-
Patel, A.C.1
Nunez, N.P.2
Perkins, S.N.3
Barrett, J.C.4
Hursting, S.D.5
-
61
-
-
1842506719
-
Metformin therapy increases insulin-like growth factor binding protein-1 in hyperinsulinemic women with polycystic ovary syndrome
-
L. Pawelczyk, R.Z. Spaczynski, B. Banaszewska, and A.J. Duleba Metformin therapy increases insulin-like growth factor binding protein-1 in hyperinsulinemic women with polycystic ovary syndrome Eur J Obstet Gynecol Reprod Biol 113 2004 209 213
-
(2004)
Eur J Obstet Gynecol Reprod Biol
, vol.113
, pp. 209-213
-
-
Pawelczyk, L.1
Spaczynski, R.Z.2
Banaszewska, B.3
Duleba, A.J.4
-
62
-
-
58149156184
-
Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERalpha negative MDA-MB-435 breast cancer model
-
K.N. Phoenix, F. Vumbaca, and K.P. Claffey Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERalpha negative MDA-MB-435 breast cancer model Breast Cancer Res Treat 113 2009 101 111
-
(2009)
Breast Cancer Res Treat
, vol.113
, pp. 101-111
-
-
Phoenix, K.N.1
Vumbaca, F.2
Claffey, K.P.3
-
63
-
-
20044370885
-
Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction
-
K. Sakamoto, A. McCarthy, D. Smith, K.A. Green, D. Grahame Hardie, and A. Ashworth Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction EMBO J 24 2005 1810 1820
-
(2005)
EMBO J
, vol.24
, pp. 1810-1820
-
-
Sakamoto, K.1
McCarthy, A.2
Smith, D.3
Green, K.A.4
Grahame Hardie, D.5
Ashworth, A.6
-
64
-
-
28844433635
-
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
-
R.J. Shaw, K.A. Lamia, D. Vasquez, S.H. Koo, N. Bardeesy, and R.A. Depinho The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin Science 310 2005 1642 1646
-
(2005)
Science
, vol.310
, pp. 1642-1646
-
-
Shaw, R.J.1
Lamia, K.A.2
Vasquez, D.3
Koo, S.H.4
Bardeesy, N.5
Depinho, R.A.6
-
65
-
-
0036735346
-
Enhanced sensitivity of multiple myeloma cells containing PTEN mutations to CCI-779
-
Y. Shi, J. Gera, L. Hu, J.H. Hsu, R. Bookstein, and W. Li Enhanced sensitivity of multiple myeloma cells containing PTEN mutations to CCI-779 Cancer Res 62 2002 5027 5034
-
(2002)
Cancer Res
, vol.62
, pp. 5027-5034
-
-
Shi, Y.1
Gera, J.2
Hu, L.3
Hsu, J.H.4
Bookstein, R.5
Li, W.6
-
66
-
-
0030667702
-
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
-
S.Y. Shieh, M. Ikeda, Y. Taya, and C. Prives DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2 Cell 91 1997 325 334
-
(1997)
Cell
, vol.91
, pp. 325-334
-
-
Shieh, S.Y.1
Ikeda, M.2
Taya, Y.3
Prives, C.4
-
67
-
-
0034947272
-
The relation of type 2 diabetes and cancer
-
H.D. Strickler, J. Wylie-Rosett, T. Rohan, D.R. Hoover, S. Smoller, and R.D. Burk The relation of type 2 diabetes and cancer Diabetes Technol Ther 3 2001 263 274
-
(2001)
Diabetes Technol Ther
, vol.3
, pp. 263-274
-
-
Strickler, H.D.1
Wylie-Rosett, J.2
Rohan, T.3
Hoover, D.R.4
Smoller, S.5
Burk, R.D.6
-
68
-
-
79952290187
-
Metformin treatment exerts antiinvasive and antimetastatic effects in human endometrial carcinoma cells
-
B.K. Tan, R. Adya, J. Chen, H. Lehnert, L.J. Sant Cassia, and H.S. Randeva Metformin treatment exerts antiinvasive and antimetastatic effects in human endometrial carcinoma cells J Clin Endocrinol Metab 96 2011 808 816
-
(2011)
J Clin Endocrinol Metab
, vol.96
, pp. 808-816
-
-
Tan, B.K.1
Adya, R.2
Chen, J.3
Lehnert, H.4
Sant Cassia, L.J.5
Randeva, H.S.6
-
69
-
-
55449124298
-
Metformin suppresses intestinal polyp growth in ApcMin/+ mice
-
A. Tomimoto, H. Endo, M. Sugiyama, T. Fujisawa, K. Hosono, and H. Takahashi Metformin suppresses intestinal polyp growth in ApcMin/+ mice Cancer Sci 99 2008 2136 2141
-
(2008)
Cancer Sci
, vol.99
, pp. 2136-2141
-
-
Tomimoto, A.1
Endo, H.2
Sugiyama, M.3
Fujisawa, T.4
Hosono, K.5
Takahashi, H.6
-
70
-
-
78650754301
-
The anti-diabetic drug metformin suppresses the metastasis-associated protein CD24 in MDA-MB-468 triple-negative breast cancer cells
-
A. Vazquez-Martin, C. Oliveras-Ferraros, S. Cufi, S. del Barco, B. Martin-Castillo, and E. Lopez-Bonet The anti-diabetic drug metformin suppresses the metastasis-associated protein CD24 in MDA-MB-468 triple-negative breast cancer cells Oncol Rep 25 2011 135 140
-
(2011)
Oncol Rep
, vol.25
, pp. 135-140
-
-
Vazquez-Martin, A.1
Oliveras-Ferraros, C.2
Cufi, S.3
Del Barco, S.4
Martin-Castillo, B.5
Lopez-Bonet, E.6
-
71
-
-
77957005003
-
Metformin regulates breast cancer stem cell ontogeny by transcriptional regulation of the epithelial-mesenchymal transition (EMT) status
-
A. Vazquez-Martin, C. Oliveras-Ferraros, S. Cufi, S. del Barco, B. Martin-Castillo, and J.A. Menendez Metformin regulates breast cancer stem cell ontogeny by transcriptional regulation of the epithelial-mesenchymal transition (EMT) status Cell Cycle 9 2010 3807 3814
-
(2010)
Cell Cycle
, vol.9
, pp. 3807-3814
-
-
Vazquez-Martin, A.1
Oliveras-Ferraros, C.2
Cufi, S.3
Del Barco, S.4
Martin-Castillo, B.5
Menendez, J.A.6
-
72
-
-
61649095657
-
The antidiabetic drug metformin: A pharmaceutical AMPK activator to overcome breast cancer resistance to HER2 inhibitors while decreasing risk of cardiomyopathy
-
A. Vazquez-Martin, C. Oliveras-Ferraros, S. del Barco, B. Martin-Castillo, and J.A. Menendez The antidiabetic drug metformin: a pharmaceutical AMPK activator to overcome breast cancer resistance to HER2 inhibitors while decreasing risk of cardiomyopathy Ann Oncol 20 2009 592 595
-
(2009)
Ann Oncol
, vol.20
, pp. 592-595
-
-
Vazquez-Martin, A.1
Oliveras-Ferraros, C.2
Del Barco, S.3
Martin-Castillo, B.4
Menendez, J.A.5
-
73
-
-
70450021431
-
MTOR inhibitors and the anti-diabetic biguanide metformin: New insights into the molecular management of breast cancer resistance to the HER2 tyrosine kinase inhibitor lapatinib (Tykerb)
-
A. Vazquez-Martin, C. Oliveras-Ferraros, S. del Barco, B. Martin-Castillo, and J.A. Menendez mTOR inhibitors and the anti-diabetic biguanide metformin: new insights into the molecular management of breast cancer resistance to the HER2 tyrosine kinase inhibitor lapatinib (Tykerb) Clin Transl Oncol 11 2009 455 459
-
(2009)
Clin Transl Oncol
, vol.11
, pp. 455-459
-
-
Vazquez-Martin, A.1
Oliveras-Ferraros, C.2
Del Barco, S.3
Martin-Castillo, B.4
Menendez, J.A.5
-
74
-
-
79954460690
-
The anti-diabetic drug metformin suppresses self-renewal and proliferation of trastuzumab-resistant tumor-initiating breast cancer stem cells
-
A. Vazquez-Martin, C. Oliveras-Ferraros, S. del Barco, B. Martin-Castillo, and J.A. Menendez The anti-diabetic drug metformin suppresses self-renewal and proliferation of trastuzumab-resistant tumor-initiating breast cancer stem cells Breast Cancer Res Treat 126 2011 355 364
-
(2011)
Breast Cancer Res Treat
, vol.126
, pp. 355-364
-
-
Vazquez-Martin, A.1
Oliveras-Ferraros, C.2
Del Barco, S.3
Martin-Castillo, B.4
Menendez, J.A.5
-
75
-
-
60749108023
-
The antidiabetic drug metformin suppresses HER2 (erbB-2) oncoprotein overexpression via inhibition of the mTOR effector p70S6K1 in human breast carcinoma cells
-
A. Vazquez-Martin, C. Oliveras-Ferraros, and J.A. Menendez The antidiabetic drug metformin suppresses HER2 (erbB-2) oncoprotein overexpression via inhibition of the mTOR effector p70S6K1 in human breast carcinoma cells Cell Cycle 8 2009 88 96
-
(2009)
Cell Cycle
, vol.8
, pp. 88-96
-
-
Vazquez-Martin, A.1
Oliveras-Ferraros, C.2
Menendez, J.A.3
-
76
-
-
12444279265
-
On the origin of cancer cells
-
O. Warburg On the origin of cancer cells Science 123 1956 309 314
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
77
-
-
14644433735
-
The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy
-
G.S. Warshamana-Greene, J. Litz, E. Buchdunger, C. Garcia-Echeverria, F. Hofmann, and G.W. Krystal The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy Clin Cancer Res 11 2005 1563 1571
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1563-1571
-
-
Warshamana-Greene, G.S.1
Litz, J.2
Buchdunger, E.3
Garcia-Echeverria, C.4
Hofmann, F.5
Krystal, G.W.6
-
78
-
-
13344270279
-
Diabetes mellitus and breast cancer
-
I. Wolf, S. Sadetzki, R. Catane, A. Karasik, and B. Kaufman Diabetes mellitus and breast cancer Lancet Oncol 6 2005 103 111
-
(2005)
Lancet Oncol
, vol.6
, pp. 103-111
-
-
Wolf, I.1
Sadetzki, S.2
Catane, R.3
Karasik, A.4
Kaufman, B.5
-
79
-
-
70350583054
-
Metformin use and prostate cancer in Caucasian men: Results from a population-based case-control study
-
J.L. Wright, and J.L. Stanford Metformin use and prostate cancer in Caucasian men: results from a population-based case-control study Cancer Causes Control 20 2009 1617 1622
-
(2009)
Cancer Causes Control
, vol.20
, pp. 1617-1622
-
-
Wright, J.L.1
Stanford, J.L.2
-
80
-
-
33751509395
-
Increased tumor growth in mice with diet-induced obesity: Impact of ovarian hormones
-
S. Yakar, N.P. Nunez, P. Pennisi, P. Brodt, H. Sun, and L. Fallavollita Increased tumor growth in mice with diet-induced obesity: impact of ovarian hormones Endocrinology 147 2006 5826 5834
-
(2006)
Endocrinology
, vol.147
, pp. 5826-5834
-
-
Yakar, S.1
Nunez, N.P.2
Pennisi, P.3
Brodt, P.4
Sun, H.5
Fallavollita, L.6
-
81
-
-
33751284806
-
Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells
-
M. Zakikhani, R. Dowling, I.G. Fantus, N. Sonenberg, and M. Pollak Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells Cancer Res 66 2006 10269 10273
-
(2006)
Cancer Res
, vol.66
, pp. 10269-10273
-
-
Zakikhani, M.1
Dowling, R.2
Fantus, I.G.3
Sonenberg, N.4
Pollak, M.5
-
82
-
-
61449113987
-
The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase
-
M. Zakikhani, R.J. Dowling, N. Sonenberg, and M.N. Pollak The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase Cancer Prev Res (Phila) 1 2008 369 375
-
(2008)
Cancer Prev Res (Phila)
, vol.1
, pp. 369-375
-
-
Zakikhani, M.1
Dowling, R.J.2
Sonenberg, N.3
Pollak, M.N.4
-
83
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
G. Zhou, R. Myers, Y. Li, Y. Chen, X. Shen, and J. Fenyk-Melody Role of AMP-activated protein kinase in mechanism of metformin action J Clin Investig 108 2001 1167 1174
-
(2001)
J Clin Investig
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
-
84
-
-
58149354390
-
Cell cycle arrest in Metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27Kip1 or p21Cip1
-
Y. Zhuang, and W.K. Miskimins Cell cycle arrest in Metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27Kip1 or p21Cip1 J Mol Signal 3 2008 18
-
(2008)
J Mol Signal
, vol.3
, pp. 18
-
-
Zhuang, Y.1
Miskimins, W.K.2
|