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Volumn 37, Issue 9, 2014, Pages 2522-2532

Metformin does not affect cancer risk: A cohort study in the U.K. clinical practice research datalink analyzed like an intention-to-treat trial

Author keywords

[No Author keywords available]

Indexed keywords

ACARBOSE; ACETOHEXAMIDE; CHLORPROPAMIDE; EXENDIN 4; GLIBENCLAMIDE; GLIBORNURIDE; GLICLAZIDE; GLIMEPIRIDE; GLIPIZIDE; GLIQUIDONE; GLYMIDINE; HEMOGLOBIN A1C; INSULIN; METFORMIN; NATEGLINIDE; ORAL ANTIDIABETIC AGENT; PIOGLITAZONE; REPAGLINIDE; ROSIGLITAZONE; SITAGLIPTIN; SULFONYLUREA; TOLAZAMIDE; TOLBUTAMIDE; VILDAGLIPTIN; ANTIDIABETIC AGENT; SULFONYLUREA DERIVATIVE;

EID: 84906691535     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc14-0584     Document Type: Article
Times cited : (156)

References (30)
  • 1
    • 84876334434 scopus 로고    scopus 로고
    • Association of metformin use with cancer incidence and mortality: A meta-analysis
    • Zhang P, Li H, Tan X, Chen L, Wang S. Association of metformin use with cancer incidence and mortality: a meta-analysis. Cancer Epidemiol 2013;37:207-218.
    • (2013) Cancer Epidemiol , vol.37 , pp. 207-218
    • Zhang, P.1    Li, H.2    Tan, X.3    Chen, L.4    Wang, S.5
  • 2
    • 84879552899 scopus 로고    scopus 로고
    • Metformin and sulfonylureas in relation to cancer risk in type II diabetes patients: A meta-analysis using primary data of published studies
    • Thakkar B, Aronis KN, Vamvini MT, Shields K, Mantzoros CS. Metformin and sulfonylureas in relation to cancer risk in type II diabetes patients: a meta-analysis using primary data of published studies. Metabolism 2013;62:922-934.
    • (2013) Metabolism , vol.62 , pp. 922-934
    • Thakkar, B.1    Aronis, K.N.2    Vamvini, M.T.3    Shields, K.4    Mantzoros, C.S.5
  • 3
    • 84866138849 scopus 로고    scopus 로고
    • Cancer outcomes and all-cause mortality in adults allocated to metformin: Systematic review and collaborative meta-analysis of randomised clinical trials
    • Stevens RJ, Ali R, Bankhead CR, et al. Cancer outcomes and all-cause mortality in adults allocated to metformin: systematic review and collaborative meta-analysis of randomised clinical trials. Diabetologia 2012;55:2593-2603.
    • (2012) Diabetologia , vol.55 , pp. 2593-2603
    • Stevens, R.J.1    Ali, R.2    Bankhead, C.R.3
  • 4
    • 84869788946 scopus 로고    scopus 로고
    • Metformin and the risk of cancer: Time-related biases in observational studies
    • Suissa S, Azoulay L. Metformin and the risk of cancer: time-related biases in observational studies. Diabetes Care 2012;35:2665-2673.
    • (2012) Diabetes Care , vol.35 , pp. 2665-2673
    • Suissa, S.1    Azoulay, L.2
  • 5
    • 61449524241 scopus 로고    scopus 로고
    • Observational studies analyzed like randomized experiments: An application to postmenopausal hormone therapy and coronary heart disease
    • Hernán MA, Alonso A, Logan R, et al. Observational studies analyzed like randomized experiments: an application to postmenopausal hormone therapy and coronary heart disease. Epidemiology 2008;19:766-779.
    • (2008) Epidemiology , vol.19 , pp. 766-779
    • Hernán, M.A.1    Alonso, A.2    Logan, R.3
  • 6
    • 0030770309 scopus 로고    scopus 로고
    • The UK general practice research database
    • Walley T,Mantgani A. The UK General Practice Research Database. Lancet 1997;350:1097-1099.
    • (1997) Lancet , vol.350 , pp. 1097-1099
    • Walley, T.1    Mantgani, A.2
  • 7
    • 7144259074 scopus 로고    scopus 로고
    • Use of the UK general practice research database for pharmacoepidemiology
    • García Rodríguez LA, Pérez Gutthann S. Use of the UK General Practice Research Database for pharmacoepidemiology. Br J Clin Pharmacol 1998;45:419-425.
    • (1998) Br J Clin Pharmacol , vol.45 , pp. 419-425
    • García Rodríguez, L.A.1    Pérez Gutthann, S.2
  • 9
    • 72949102852 scopus 로고    scopus 로고
    • Validation and validity of diagnoses in the General Practice Research Database: A systematic review
    • Herrett E, Thomas SL, Schoonen WM, Smeeth L, Hall AJ. Validation and validity of diagnoses in the General Practice Research Database: a systematic review. Br J Clin Pharmacol 2010;69:4-14.
    • (2010) Br J Clin Pharmacol , vol.69 , pp. 4-14
    • Herrett, E.1    Thomas, S.L.2    Schoonen, W.M.3    Smeeth, L.4    Hall, A.J.5
  • 10
    • 63349104529 scopus 로고    scopus 로고
    • Menopausal status and physical performance in midlife: Findings from a British birth cohort study
    • Cooper R, Mishra G, Clennell S, Guralnik J, Kuh D. Menopausal status and physical performance in midlife: findings from a British birth cohort study. Menopause 2008;15:1079-1085.
    • (2008) Menopause , vol.15 , pp. 1079-1085
    • Cooper, R.1    Mishra, G.2    Clennell, S.3    Guralnik, J.4    Kuh, D.5
  • 11
    • 28844433635 scopus 로고    scopus 로고
    • The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
    • Shaw RJ, Lamia KA, Vasquez D, et al. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science 2005;310:1642-1646.
    • (2005) Science , vol.310 , pp. 1642-1646
    • Shaw, R.J.1    Lamia, K.A.2    Vasquez, D.3
  • 12
    • 34547114031 scopus 로고    scopus 로고
    • Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth
    • BuzzaiM, Jones RG, Amaravadi RK, et al. Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth. Cancer Res 2007;67:6745-6752.
    • (2007) Cancer Res , vol.67 , pp. 6745-6752
    • Buzzai, M.1    Jones, R.G.2    Amaravadi, R.K.3
  • 13
    • 33751284806 scopus 로고    scopus 로고
    • Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells
    • Zakikhani M, Dowling R, Fantus IG, Sonenberg N, Pollak M. Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells. Cancer Res 2006;66:10269-10273.
    • (2006) Cancer Res , vol.66 , pp. 10269-10273
    • Zakikhani, M.1    Dowling, R.2    Fantus, I.G.3    Sonenberg, N.4    Pollak, M.5
  • 14
    • 77953539812 scopus 로고    scopus 로고
    • Long-term metformin use is associated with decreased risk of breast cancer
    • Bodmer M, Meier C, Krähenbühl S, Jick SS, Meier CR. Long-term metformin use is associated with decreased risk of breast cancer. Diabetes Care 2010;33:1304-1308.
    • (2010) Diabetes Care , vol.33 , pp. 1304-1308
    • Bodmer, M.1    Meier, C.2    Krähenbühl, S.3    Jick, S.S.4    Meier, C.R.5
  • 15
    • 33645766204 scopus 로고    scopus 로고
    • Increased cancer-related mortality for patients with type 2 diabeteswho use sulfonylureas or insulin
    • Bowker SL, Majumdar SR, Veugelers P, Johnson JA. Increased cancer-related mortality for patients with type 2 diabeteswho use sulfonylureas or insulin. Diabetes Care 2006;29:254-258.
    • (2006) Diabetes Care , vol.29 , pp. 254-258
    • Bowker, S.L.1    Majumdar, S.R.2    Veugelers, P.3    Johnson, J.A.4
  • 16
    • 68449094325 scopus 로고    scopus 로고
    • The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
    • Currie CJ, Poole CD, Gale EA. The influence of glucose-lowering therapies on cancer risk in type 2 diabetes. Diabetologia 2009;52:1766-1777.
    • (2009) Diabetologia , vol.52 , pp. 1766-1777
    • Currie, C.J.1    Poole, C.D.2    Gale, E.A.3
  • 21
    • 69549097703 scopus 로고    scopus 로고
    • New users of metformin are at low risk of incident cancer: A cohort study among people with type 2 diabetes
    • Libby G, Donnelly LA, Donnan PT, Alessi DR, Morris AD, Evans JM. New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes. Diabetes Care 2009;32:1620-1625.
    • (2009) Diabetes Care , vol.32 , pp. 1620-1625
    • Libby, G.1    Donnelly, L.A.2    Donnan, P.T.3    Alessi, D.R.4    Morris, A.D.5    Evans, J.M.6
  • 22
    • 79956226830 scopus 로고    scopus 로고
    • Cohort study of pioglitazone and cancer incidence in patients with diabetes
    • Ferrara A, Lewis JD, Quesenberry CP Jr, et al. Cohort study of pioglitazone and cancer incidence in patients with diabetes. Diabetes Care 2011;34:923-929.
    • (2011) Diabetes Care , vol.34 , pp. 923-929
    • Ferrara, A.1    Lewis, J.D.2    Quesenberry, Jr.C.P.3
  • 23
    • 84874322688 scopus 로고    scopus 로고
    • Initial metformin or sulphonylurea exposure and cancer occurrence among patients with type 2 diabetes mellitus
    • Qiu H, Rhoads GG, Berlin JA, Marcella SW, Demissie K. Initial metformin or sulphonylurea exposure and cancer occurrence among patients with type 2 diabetes mellitus. Diabetes Obes Metab 2013;15:349-357.
    • (2013) Diabetes Obes Metab , vol.15 , pp. 349-357
    • Qiu, H.1    Rhoads, G.G.2    Berlin, J.A.3    Marcella, S.W.4    Demissie, K.5
  • 24
    • 84856698481 scopus 로고    scopus 로고
    • Glucose-lowering agents and the patterns of risk for cancer: A study with the General Practice Research Database and secondary care data
    • van Staa TP, Patel D, Gallagher AM, de Bruin ML. Glucose-lowering agents and the patterns of risk for cancer: a study with the General Practice Research Database and secondary care data. Diabetologia 2012;55:654-665.
    • (2012) Diabetologia , vol.55 , pp. 654-665
    • Van Staa, T.P.1    Patel, D.2    Gallagher, A.M.3    De Bruin, M.L.4
  • 25
  • 26
    • 84872019209 scopus 로고    scopus 로고
    • The use of metformin and the incidence of lung cancer in patients with type 2 diabetes
    • Smiechowski BB, Azoulay L, Yin H, Pollak MN, Suissa S. The use of metformin and the incidence of lung cancer in patients with type 2 diabetes. Diabetes Care 2013;36:124-129.
    • (2013) Diabetes Care , vol.36 , pp. 124-129
    • Smiechowski, B.B.1    Azoulay, L.2    Yin, H.3    Pollak, M.N.4    Suissa, S.5
  • 27
    • 84867998462 scopus 로고    scopus 로고
    • Associations of type 2 diabetes and diabetes treatment with breast cancer risk and mortality: A population-based cohort study among British women
    • Redaniel MT, Jeffreys M, May MT, Ben- Shlomo Y, Martin RM. Associations of type 2 diabetes and diabetes treatment with breast cancer risk and mortality: a population-based cohort study among British women. Cancer Causes Control 2012;23:1785-1795.
    • (2012) Cancer Causes Control , vol.23 , pp. 1785-1795
    • Redaniel, M.T.1    Jeffreys, M.2    May, M.T.3    Ben- Shlomo, Y.4    Martin, R.M.5
  • 29
    • 33845405222 scopus 로고    scopus 로고
    • Glycemic durability of rosiglitazone metformin or glyburide monotherapy
    • ADOPT Study Group
    • Kahn SE, Haffner SM, Heise MA, et al.; ADOPT Study Group. Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. N Engl J Med 2006;355:2427-2443.
    • (2006) N Engl J Med , vol.355 , pp. 2427-2443
    • Kahn, S.E.1    Haffner, S.M.2    Heise, M.A.3
  • 30
    • 67149146438 scopus 로고    scopus 로고
    • Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): A multicentre randomised open-label trial
    • RECORD Study Team
    • Home PD, Pocock SJ, Beck-Nielsen H, et al.; RECORD Study Team. Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial. Lancet 2009;373:2125-2135.
    • (2009) Lancet , vol.373 , pp. 2125-2135
    • Home, P.D.1    Pocock, S.J.2    Beck-Nielsen, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.