Reactive oxygen species mediate nitric oxide production through ERK/JNK MAPK signaling in HAPI microglia after PFOS exposure

Toxicology and Applied Pharmacology

Volumn 288, Issue 2, 2015, Pages 143-151

  Wang, Cheng ^a   Nie, Xiaoke ^a   Zhang, Yan ^a   Li, Ting ^a   Mao, Jiamin ^a   Liu, Xinhang ^a   Gu, Yiyang ^a   Shi, Jiyun ^a   Xiao, Jing ^a   Wan, Chunhua ^a   Wu, Qiyun ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

ERK JNK MAPK; INOS; Microglia; NO; PFOS; ROS

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ACETYLCYSTEINE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PERFLUOROOCTANESULFONIC ACID; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; ALKANESULFONIC ACID; ANTIOXIDANT; AUTACOID; FLUOROCARBON; NOS2 PROTEIN, RAT; POLLUTANT; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; IMMUNOFLUORESCENCE TEST; INFLAMMATION; MACROPHAGE ACTIVATION; MEDIATOR RELEASE; MICROGLIA; NERVE CELL NECROSIS; NONHUMAN; OXIDATIVE STRESS; RAT; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; HUMAN; METABOLISM; NERVE CELL; PARACRINE SIGNALING; PATHOLOGY; POLLUTANT; TIME; TOXICITY; TUMOR CELL LINE;

ALKANESULFONIC ACIDS; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLUOROCARBONS; HUMANS; INFLAMMATION MEDIATORS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICROGLIA; NEURONS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PARACRINE COMMUNICATION; PROTEIN KINASE INHIBITORS; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84942293952     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2015.06.012     Document Type: Article

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