Both sub-acute, moderate-dose and short-term, low-dose dietary exposure of mice to perfluorooctane sulfonate exacerbates concanavalin A-induced hepatitis

Toxicology Letters

Volumn 217, Issue 1, 2013, Pages 67-74

  Qazi, Mousumi Rahman ^a   Hassan, Moustapha ^b   Nelson, B Dean ^a   DePierre, Joseph W ^a   Abedi Valugerdi, Manuchehr ^a,b,c  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c ImmunoBioTox (IBT) AB   (Sweden)

Author keywords

Concanavalin A; Hepatitis; Hepatomegaly; Perfluorooctane sulfonate; Pro inflammatory cytokines

Indexed keywords

ALANINE AMINOTRANSFERASE; AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CONCANAVALIN A; CYTOKINE; DNA; GAMMA INTERFERON; PERFLUOROOCTANESULFONIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD SAMPLING; BODY WEIGHT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIETARY INTAKE; DISEASE EXACERBATION; DNA FRAGMENTATION; DRUG EFFICACY; DRUG EXPOSURE; DRUG SAFETY; IMMUNE RESPONSE; LIVER; LIVER INJURY; LOW DRUG DOSE; MALE; MEDIATOR; MOUSE; NONHUMAN; PRIORITY JOURNAL; TOXIC HEPATITIS;

ALKANESULFONIC ACIDS; ANIMALS; APOPTOSIS; CONCANAVALIN A; CYTOKINES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-INDUCED LIVER INJURY; ENVIRONMENTAL POLLUTANTS; FLUOROCARBONS; HEPATOMEGALY; IMMUNOLOGIC FACTORS; LIVER; MALE; MICE; MICE, INBRED C57BL; RANDOM ALLOCATION; TIME FACTORS; TRANSAMINASES;

MUS; RODENTIA;

EID: 84872152933     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.12.001     Document Type: Article

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