Perfluorooctane sulfonate induces apoptosis of cerebellar granule cells via a ROS-dependent protein kinase C signaling pathway

NeuroToxicology

Volumn 33, Issue 3, 2012, Pages 314-320

  Lee, Hyun Gyo ^a   Lee, Youn Ju ^a   Yang, Jae Ho ^a  

^a Catholic University of Daegu   (South Korea)

Author keywords

Apoptosis; Cerebellar granule cell; Perfluorooctane sulfonate; Protein kinase C; ROS

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; PERFLUOROOCTANESULFONIC ACID; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C BETA II; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C LAMBDA; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; CELL FRACTIONATION; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CEREBELLUM; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; ENZYME ACTIVITY; FLUORESCENCE MICROSCOPY; GENE TRANSLOCATION; GENETIC TRANSFECTION; GRANULE CELL; LEARNING; LONG TERM POTENTIATION; MEMORY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ALKANESULFONIC ACIDS; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CASPASE 3; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FLUOROCARBONS; IN SITU NICK-END LABELING; ISOENZYMES; NEURONS; NEUROTOXICITY SYNDROMES; OXIDATIVE STRESS; PROTEIN KINASE C; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSFECTION;

RATTUS;

EID: 84862799814     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2012.01.017     Document Type: Article

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