JNK and NADPH oxidase involved in fluoride-induced oxidative stress in BV-2 microglia cells

Mediators of Inflammation

Volumn 2013, Issue , 2013, Pages

  Yan, Ling ^a   Liu, Shengnan ^a   Wang, Chen ^a   Wang, Fei ^a   Song, Yingli ^a   Yan, Nan ^a   Xi, Shuhua ^a   Liu, Ziyou ^a   Sun, Guifan ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; APOCYNIN; FLUORIDE; INTERLEUKIN 1BETA; MELATONIN; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; ACETOPHENONE DERIVATIVE; ANTHRA(1,9 CD)PYRAZOL 6(2H) ONE; ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONE; ANTHRACENE DERIVATIVE; ANTIOXIDANT; ENZYME INHIBITOR; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; NITRIC OXIDE; OXYGEN;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL GROWTH; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; IMMUNOCYTOCHEMISTRY; MICROGLIA; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REDUCTION; WESTERN BLOTTING; ANIMAL; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; GENE EXPRESSION REGULATION; INFLAMMATION; METABOLISM; PHOSPHORYLATION; DRUG EFFECTS;

ACETOPHENONES; ANIMALS; ANTHRACENES; ANTIOXIDANTS; CELL LINE; CELL SURVIVAL; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORIDES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INFLAMMATION; MAP KINASE KINASE 4; MELATONIN; MICE; MICROGLIA; NADPH OXIDASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; OXYGEN; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES;

EID: 84884276328     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2013/895975     Document Type: Article

References (45)

1. Ozsvath D. L., Fluoride and environmental health: a review. Reviews in Environmental Science and Biotechnology 2009 8 1 59 79 2-s2.0-67649203239 10.1007/s11157-008-9136-9
2. Ekambaram P., Paul V., Calcium preventing locomotor behavioral and dental toxicities of fluoride by decreasing serum fluoride level in rats. Environmental Toxicology and Pharmacology 2001 9 4 141 146 2-s2.0-0035071878 10.1016/S1382-6689(00)00063-6
3. Paul V., Ekambaram P., Jayakumar A. R., Effects of sodium fluoride on locomotor behavior and a few biochemical parameters in rats. Environmental Toxicology and Pharmacology 1998 6 3 187 191 2-s2.0-0031761921 10.1016/S1382-6689(98)00033-7
4. Bhatnagar M., Rao P., Jain S., Bhatnagar R., Neurotoxicity of fluoride: neurodegeneration in hippocampus of female mice. Indian Journal of Experimental Biology 2002 40 5 546 554 2-s2.0-0036013719
5. Choi A. L., Sun G., Zhang Y., Grandjean P., Developmental fluoride neurotoxicity: a systematic review and meta-analysis. Environmental Health Perspectives 2012 120 10 1362 1368
6. Xiang Q., Liang Y., Chen L., Wang C., Chen B., Chen X., Zhou M., Effect of fluoride in drinking water on children's intelligence. Fluoride 2003 36 2 84 94 2-s2.0-0042991481
7. Tang Q. Q., Du J., Ma H. H., Jiang S. J., Zhou X. J., Fluoride and children's intelligence: a meta-analysis. Biological Trace Element Research 2008 126 1-3 115 120 2-s2.0-64849084248 10.1007/s12011-008-8204-x
8. Zhang M., Wang A., He W., He P., Xu B., Xia T., Chen X., Yang K., Effects of fluoride on the expression of NCAM, oxidative stress, and apoptosis in primary cultured hippocampal neurons. Toxicology 2007 236 3 208 216 2-s2.0-34347211369 10.1016/j.tox.2007.04.007
9. Butterfield D. A., Oxidative stress in neurodegenerative disorders. Antioxidants and Redox Signaling 2006 8 11-12 1971 1973 2-s2.0-33947626638
10. Donnelly D. F., Carroll J. L., Mitochondrial function and carotid body transduction. High Altitude Medicine & Biology 2005 6 2 121 132 2-s2.0-25844457269 10.1089/ham.2005.6.121
11. Chinoy N. J., Patel T. N., The influence of fluoride and/or aluminium on free radical toxicity in the brain of female mice and beneficial effects of some anti-dotes. Fluoride 2000 33 1 S8
12. Georgieva N. V., Oxidative stress as a factor of disrupted ecological oxidative balance in biological systems-a review. Bulgarian Journal of Veterinary Medicine 2005 8 1 11
13. Shuhua X., Ziyou L., Ling Y., Fei W., Guifan S., A role of fluoride on free radical generation and oxidative stress in BV-2 microGlia cells. Mediators of Inflammation 2012 2012 8 102954 10.1155/2012/102954
14. Aloisi F., Immune function of microGlia. Glia 2001 36 2 165 179 2-s2.0-0035152836 10.1002/Glia.1106
15. Rock R. B., Gekker G., Hu S., Sheng W. S., Cheeran M., Lokensgard J. R., Peterson P. K., Role of microGlia in central nervous system infections. Clinical Microbiology Reviews 2004 17 4 942 964 2-s2.0-5644271409 10.1128/CMR.17.4.942- 964.2004
16. McGeer P. L., Itagaki S., Boyes B. E., McGeer E. G., Reactive microGlia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 1988 38 8 1285 1291 2-s2.0-0023789193
17. Giulian D., Haverkamp L. J., Li J., Senile plaques stimulate microGlia to release a neurotoxin found in Alzheimer brain. Neurochemistry International 1995 27 1 119 137 2-s2.0-0029040685 10.1016/0197-0186(95)00067-I
18. Rockwell P., Martinez J., Papa L., Gomes E., Redox regulates COX-2 upregulation and cell death in the neuronal response to cadmium. Cellular Signalling 2004 16 3 343 353 2-s2.0-0346996446 10.1016/j.cellsig.2003.08.006
19. Svensson C., Fernaeus S. Z., Part K., Reis K., Land T., LPS-induced iNOS expression in Bv-2 cells is suppressed by an oxidative mechanism acting on the JNK pathway-a potential role for neuroprotection. Brain Research 2010 1322 1 7 2-s2.0-77649235966 10.1016/j.brainres.2010.01.082
20. Pocivavsek A., Burns M. P., Rebeck G. W., Low-density lipoprotein receptors regulate microGlial inflammation through c-Jun N-terminal kinase. Glia 2009 57 4 444 453 2-s2.0-66249122077 10.1002/Glia.20772
21. Emre Y., Hurtaud C., Nübel T., Criscuolo F., Ricquier D., Cassard-Doulcier A.-M., Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages. Biochemical Journal 2007 402 2 271 278 2-s2.0-33847698059 10.1042/BJ20061430
22. Thrane E. V., Refsnes M., Thoresen G. H., Lag M., Schwarze P. E., Fluoride-induced apoptosis in epithelial lung cells involves activation of MAP kinases p38 and possibly JNK. Toxicological Sciences 2001 61 1 83 91 2-s2.0-0035041429 10.1093/toxsci/61.1.83
23. Refsnes M., Skuland T., Schwarze P. E., Ovrevik J., Lag M., Fluoride-induced IL-8 release in human epithelial lung cells: relationship to EGF-receptor-, SRC- and MAP-kinase activation. Toxicology and Applied Pharmacology 2008 227 1 56 67 2-s2.0-38749144704 10.1016/j.taap.2007.09.022
24. Refsnes M., Thrane E. V., Lag M., Hege Thoresen G., Schwarze P. E., Mechanisms in fluoride-induced interleukin-8 synthesis in human lung epithelial cells. Toxicology 2001 167 2 145 158 2-s2.0-0035888054 10.1016/S0300-483X(01) 00448-6
25. Yuan H., Perry C. N., Huang C., Iwai-Kanai E., Carreira R. S., Glembotski C. C., Gottlieb R. A., LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection. American Journal of Physiology 2009 296 2 H470 H479 2-s2.0-61949346360 10.1152/ajpheart.01051.2008
26. Bruce S., Fluoride and intelligence. Fluoride 2000 33 2 49 52 2-s2.0-0033740094
27. Chioca L. R., Raupp I. M., Da Cunha C., Losso E. M., Andreatini R., Subchronic fluoride intake induces impairment in habituation and active avoidance tasks in rats. European Journal of Pharmacology 2008 579 1-3 196 201 2-s2.0-37549009200 10.1016/j.ejphar.2007.10.019
28. García-Montalvo E. A., Reyes-Pérez H., Del Razo L. M., Fluoride exposure impairs glucose tolerance via decreased insulin expression and oxidative stress. Toxicology 2009 263 2-3 75 83 2-s2.0-68549115156 10.1016/j.tox.2009.06.008
29. Izquierdo-Vega J. A., Sánchez-Gutiérrez M., Del Razo L. M., Decreased in vitro fertility in male rats exposed to fluoride-induced oxidative stress damage and mitochondrial transmembrane potential loss. Toxicology and Applied Pharmacology 2008 230 3 352 357 2-s2.0-46749109555 10.1016/j.taap.2008. 03.008
30. Kraft A. D., Jean Harry G., Features of microGlia and neuroinflammation relevant to environmental exposure and neurotoxicity. International Journal of Environmental Research and Public Health 2011 8 7 2980 3018 2-s2.0-79960784323 10.3390/ijerph8072980
31. Chao C. C., Hu S., Ehrlich L., Peterson P. K., Interleukin-1 and tumor necrosis factor- α synergistically mediate neurotoxicity: involvement of nitric oxide and of N -methyl-D-aspartate receptors. Brain, Behavior, and Immunity 1995 9 4 355 365 2-s2.0-0029620390 10.1006/brbi.1995.1033
32. Chew L.-J., Takanohashi A., Bell M., MicroGlia and inflammation: impact on developmental brain injuries. Mental Retardation and Developmental Disabilities Research Reviews 2006 12 2 105 112 2-s2.0-33745685998 10.1002/mrdd.20102
33. Irani K., Oxidant signaling in vascular cell growth, death, and survival: a review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling. Circulation Research 2000 87 3 179 183 2-s2.0-0033886373
34. Bhat N. R., Zhang P., Lee J. C., Hogan E. L., Extracellular signal-regulated kinase and p38 subgroups of mitogen- activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor- α gene expression in endotoxin-stimulated primary Glial cultures. Journal of Neuroscience 1998 18 5 1633 1641 2-s2.0-0032032424
35. Hidding U., Mielke K., Waetzig V., Brecht S., Hanisch U., Behrens A., Wagner E., Herdegen T., The c-Jun N-terminal kinases in cerebral microGlia: immunological functions in the brain. Biochemical Pharmacology 2002 64 5-6 781 788 2-s2.0-0036710505 10.1016/S0006-2952(02)01139-5
36. Baldwin A. S. Jr., The transcription factor NF- B and human disease. Journal of Clinical Investigation 2001 107 1 3 6 2-s2.0-0035174615
37. Chandrasekar B., Freeman G. L., Induction of nuclear factor B and activation protein 1 in postischemic myocardium. FEBS Letters 1997 401 1 30 34 2-s2.0-0031014865 10.1016/S0014-5793(96)01426-3
38. Chen Z., Gibson T. B., Robinson F., Silvestro L., Pearson G., Xu B.-E., Wright A., Vanderbilt C., Cobb M. H., MAP kinases. Chemical Reviews 2001 101 8 2449 2476 2-s2.0-0035413618 10.1021/cr000241p
39. Kyriakis J. M., Avruch J., Sounding the alarm: protein kinase cascades activated by stress and inflammation. Journal of Biological Chemistry 1996 271 40 24313 24316 2-s2.0-0029744885 10.1074/jbc.271.40.24313
40. Lau K. H., Baylink D. J., Molecular mechanism of action of fluoride on bone cells. Journal of Bone and Mineral Research 1998 13 11 1660 1667 2-s2.0-0031722817 10.1359/jbmr.1998.13.11.1660
41. Karmann K., Min W., Fanslow W. C., Pober J. S., Activation and homologous desensitization of human endothelial cells by CD40 ligand, tumor necrosis factor, and interleukin 1. Journal of Experimental Medicine 1996 184 1 173 182 2-s2.0-0030054637 10.1084/jem.184.1.173
42. McCubrey J. A., LaHair M. M., Franklin R. A., Reactive oxygen species-induced activation of the MAP kinase signaling pathways. Antioxidants & Redox Signaling 2006 8 9-10 1775 1789 2-s2.0-33750909999 10.1089/ars.2006.8.1775
43. Torres M., Forman H. J., Redox signaling and the MAP kinase pathways. Biofactors 2003 17 1-4 287 296 2-s2.0-0142043984
44. Reiter R. J., Melchiorri D., Sewerynek E., Poeggeler B., Barlow Walden L., Chuang J. I., Ortiz G. G., Acuna Castroviejo D., A review of the evidence supporting melatonin's role as an antioxidant. Journal of Pineal Research 1995 18 1 1 11 2-s2.0-0029105296
45. Agrawal R., Tyagi E., Shukla R., Nath C., Effect of insulin and melatonin on acetylcholinesterase activity in the brain of amnesic mice. Behavioural Brain Research 2008 189 2 381 386 2-s2.0-41149117860 10.1016/j.bbr.2008.01.015