Isoorientin attenuates lipopolysaccharide-induced pro-inflammatory responses through down-regulation of ROS-related MAPK/NF-κB signaling pathway in BV-2 microglia

Molecular and Cellular Biochemistry

Volumn 386, Issue 1-2, 2014, Pages 153-165

  Yuan, Li ^a   Wu, Yuchen ^a   Ren, Xiaomeng ^a   Liu, Qian ^a   Wang, Jing ^a   Liu, Xuebo ^a  

^a NORTHWEST A F UNIVERSITY   (China)

Author keywords

Isoorientin; MAPK kinases; Microglia; Neuroinflammatory; NF B; ROS

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; ISOORIENTIN; LAMIN B; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PYRROLIDINE DITHIOCARBAMATE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOTOXICITY; ENZYME ACTIVATION; MICROGLIA; MOUSE; NERVE CELL LESION; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; BLOTTING, WESTERN; CELL LINE; CYTOKINES; DOWN-REGULATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; INFLAMMATION; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; LUTEOLIN; MAP KINASE SIGNALING SYSTEM; MICE; MICROGLIA; NF-KAPPA B; NITRIC OXIDE; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84891534157     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-013-1854-9     Document Type: Article

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