메뉴 건너뛰기




Volumn 42, Issue 4, 2014, Pages 869-889

Lotus leaf (nelumbo nucifera) and its active constituents prevent inflammatory responses in macrophages via JNK/NF-κB signaling pathway

Author keywords

Anti Inflammation; JNK; Lipopolysaccharide (LPS); Nelumbo nucifera Gaertn (NNE); NF B

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CATECHIN; CYCLOOXYGENASE 2; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE; NELUMBO NUCIFERA EXTRACT; QUERCETIN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; AUTACOID; MESSENGER RNA; NOS2 PROTEIN, MOUSE; PLANT EXTRACT; PTGS2 PROTEIN, MOUSE;

EID: 84904330544     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X14500554     Document Type: Article
Times cited : (78)

References (51)
  • 1
    • 24144461211 scopus 로고    scopus 로고
    • Effect of inflammation on cyclooxygenase (COX)-2 expression in benign and malignant oesophageal cells
    • Abdalla, S.I., I.R. Sanderson and R.C. Fitzgerald. Effect of inflammation on cyclooxygenase (COX)-2 expression in benign and malignant oesophageal cells. Carcinogenesis 26: 1627-1633, 2005.
    • (2005) Carcinogenesis , vol.26 , pp. 1627-1633
    • Abdalla, S.I.1    Sanderson, I.R.2    Fitzgerald, R.C.3
  • 2
    • 2542455472 scopus 로고    scopus 로고
    • INOS-mediated nitric oxide production and its regulation
    • Aktan, F. iNOS-mediated nitric oxide production and its regulation. Life Sci. 75: 639-653, 2004.
    • (2004) Life Sci. , vol.75 , pp. 639-653
    • Aktan, F.1
  • 3
    • 0035425503 scopus 로고    scopus 로고
    • Nitric oxide synthases: Structure, function and inhibition
    • Alderton, W.K., C.E. Cooper and R.G. Knowles. Nitric oxide synthases: Structure, function and inhibition. Biochem. J. 357: 593-615, 2001.
    • (2001) Biochem. J. , vol.357 , pp. 593-615
    • Alderton, W.K.1    Cooper, C.E.2    Knowles, R.G.3
  • 4
    • 0036261025 scopus 로고    scopus 로고
    • The pulmonary physician in critical care. 5: Acute lung injury and the acute respiratory distress syndrome: Definitions and epidemiology
    • Atabai, K. and M.A. Matthay. The pulmonary physician in critical care. 5: Acute lung injury and the acute respiratory distress syndrome: Definitions and epidemiology. Thorax. 57: 452-458, 2002.
    • (2002) Thorax. , vol.57 , pp. 452-458
    • Atabai, K.1    Matthay, M.A.2
  • 5
    • 3843106031 scopus 로고    scopus 로고
    • Toll-like receptor stimulation induces airway hyper-responsiveness to bradykinin, an effect mediated by JNK and NF-kappa B signaling pathways
    • Bachar, O., M. Adner, R. Uddman and L.O. Cardell. Toll-like receptor stimulation induces airway hyper-responsiveness to bradykinin, an effect mediated by JNK and NF-kappa B signaling pathways. Eur. J. Immunol. 34: 1196-1207, 2004.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 1196-1207
    • Bachar, O.1    Adner, M.2    Uddman, R.3    Cardell, L.O.4
  • 6
    • 0028579731 scopus 로고
    • Cytokines and macrophages
    • Cavaillon, J.M. Cytokines and macrophages. Biomed. Pharmacother. 48: 445-453, 1994.
    • (1994) Biomed. Pharmacother. , vol.48 , pp. 445-453
    • Cavaillon, J.M.1
  • 7
    • 0034213030 scopus 로고    scopus 로고
    • Oroxylin A inhibition of lipopolysaccharide-induced iNOS and COX-2 gene expression via suppression of nuclear factor-kappaB activation
    • Chen, Y., L. Yang and T.J. Lee. Oroxylin A inhibition of lipopolysaccharide-induced iNOS and COX-2 gene expression via suppression of nuclear factor-kappaB activation. Biochem. Pharmacol. 59: 1445-1457, 2000.
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 1445-1457
    • Chen, Y.1    Yang, L.2    Lee, T.J.3
  • 8
    • 78650510594 scopus 로고    scopus 로고
    • Pyrrolidine dithiocarbamate (PDTC)/Cu complex induces lung epithelial cell apoptosis through mitochondria and ER-stress pathways
    • Chen, Y.W., K.L. Chen, C.H. Chen, H.C. Wu, C.C. Su, C.C. Wu, T.D. Way, D.Z. Hung, C.C. Yen, Y.T. Yang and T.H. Lu. Pyrrolidine dithiocarbamate (PDTC)/Cu complex induces lung epithelial cell apoptosis through mitochondria and ER-stress pathways. Toxicol. Lett. 199: 333-340, 2010.
    • (2010) Toxicol. Lett. , vol.199 , pp. 333-340
    • Chen, Y.W.1    Chen, K.L.2    Chen, C.H.3    Wu, H.C.4    Su, C.C.5    Wu, C.C.6    Way, T.D.7    Hung, D.Z.8    Yen, C.C.9    Yang, Y.T.10    Lu, T.H.11
  • 10
    • 57149106968 scopus 로고    scopus 로고
    • Interleukin-6 acts in the fashion of a classical chemokine on monocytic cells by inducing integrin activation, cell adhesion, actin polymerization, chemotaxis, and transmigration
    • Clahsen, T. and F. Schaper. Interleukin-6 acts in the fashion of a classical chemokine on monocytic cells by inducing integrin activation, cell adhesion, actin polymerization, chemotaxis, and transmigration. J. Leukoc. Biol. 84: 1521-1529, 2008.
    • (2008) J. Leukoc. Biol. , vol.84 , pp. 1521-1529
    • Clahsen, T.1    Schaper, F.2
  • 11
    • 0035125632 scopus 로고    scopus 로고
    • Bacterial infections and inflammation in the lungs of cystic fibrosis patients
    • Conese, M. and B.M. Assael. Bacterial infections and inflammation in the lungs of cystic fibrosis patients. Pediatr. Infect. Dis. J. 20: 207-213, 2001.
    • (2001) Pediatr. Infect. Dis. J. , vol.20 , pp. 207-213
    • Conese, M.1    Assael, B.M.2
  • 12
    • 34247580832 scopus 로고    scopus 로고
    • JNK pathway: Diseases and therapeutic potential
    • Cui, J., M. Zhang, Y.Q. Zhang and Z.H. Xu. JNK pathway: Diseases and therapeutic potential. Acta. Pharmacol. Sin. 28: 601-608, 2007.
    • (2007) Acta. Pharmacol. Sin. , vol.28 , pp. 601-608
    • Cui, J.1    Zhang, M.2    Zhang, Y.Q.3    Xu, Z.H.4
  • 13
    • 0028675999 scopus 로고
    • Cytokines, inflammation, and brain injury: Role of tumor necrosis factor-alpha
    • Feuerstein, G.Z., T. Liu and F.C. Barone. Cytokines, inflammation, and brain injury: Role of tumor necrosis factor-alpha. Cerebrovasc. Brain Metab. Rev. 6: 341-360, 1994.
    • (1994) Cerebrovasc. Brain Metab. Rev. , vol.6 , pp. 341-360
    • Feuerstein, G.Z.1    Liu, T.2    Barone, F.C.3
  • 14
    • 54949147176 scopus 로고    scopus 로고
    • New regulators of NF-kappaB in inflammation
    • Ghosh, S. and M.S. Hayden. New regulators of NF-kappaB in inflammation. Nat. Rev. Immunol. 8: 837-848, 2008.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 837-848
    • Ghosh, S.1    Hayden, M.S.2
  • 16
    • 79957653522 scopus 로고    scopus 로고
    • Attenuation of the cardiac inflammatory changes and lipid anomalies by (-)-epigallocatechin-gallate in cigarette smoke-exposed rats
    • Gokulakrisnan, A., B. Jayachandran Dare and C. Thirunavukkarasu. Attenuation of the cardiac inflammatory changes and lipid anomalies by (-)-epigallocatechin-gallate in cigarette smoke-exposed rats. Mol. Cell. Biochem. 354: 1-10, 2011.
    • (2011) Mol. Cell. Biochem. , vol.354 , pp. 1-10
    • Gokulakrisnan, A.1    Jayachandran Dare, B.2    Thirunavukkarasu, C.3
  • 17
    • 0034687729 scopus 로고    scopus 로고
    • C-Jun N-terminal kinase (JNK) repression during the inflammatory response? Just say NO
    • Hall, J.P., E. Merithew and R.J. Davis. c-Jun N-terminal kinase (JNK) repression during the inflammatory response? Just say NO. Proc. Natl. Acad. Sci. USA 97: 14022-14024, 2000.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 14022-14024
    • Hall, J.P.1    Merithew, E.2    Davis, R.J.3
  • 18
    • 84863675803 scopus 로고    scopus 로고
    • Berberine ameliorates pro-inflammatory cytokine-induced endoplasmic reticulum stress in human intestinal epithelial cells in vitro
    • Hao, X., A. Yao, J. Gong, W. Zhu, N. Li and J. Li. Berberine ameliorates pro-inflammatory cytokine-induced endoplasmic reticulum stress in human intestinal epithelial cells in vitro. Inflammation 35: 841-849, 2012.
    • (2012) Inflammation , vol.35 , pp. 841-849
    • Hao, X.1    Yao, A.2    Gong, J.3    Zhu, W.4    Li, N.5    Li, J.6
  • 19
    • 0037336996 scopus 로고    scopus 로고
    • Inhibition of the iNOS pathway in inflammatory macrophages by low-dose X-irradiation in vitro. Is there a time dependence?
    • Hildebrandt, G., G. Loppnow, J. Jahns, M. Hindemith, U. Anderegg, A. Saalbach and F. Kamprad. Inhibition of the iNOS pathway in inflammatory macrophages by low-dose X-irradiation in vitro. Is there a time dependence? Strahlenther. Onkol. 179: 158-166, 2003.
    • (2003) Strahlenther. Onkol. , vol.179 , pp. 158-166
    • Hildebrandt, G.1    Loppnow, G.2    Jahns, J.3    Hindemith, M.4    Anderegg, U.5    Saalbach, A.6    Kamprad, F.7
  • 20
    • 84872684244 scopus 로고    scopus 로고
    • Yuwen02f1 suppresses LPS-induced endotoxemia and adjuvant-induced arthritis primarily through blockade of ROS formation, NFkB and MAPK activation
    • Hsu, C.C., J.C. Lien, C.W. Chang, C.H. Chang, S.C. Kuo and T.F. Huang. Yuwen02f1 suppresses LPS-induced endotoxemia and adjuvant-induced arthritis primarily through blockade of ROS formation, NFkB and MAPK activation. Biochem. Pharmacol. 85: 385-395, 2013.
    • (2013) Biochem. Pharmacol. , vol.85 , pp. 385-395
    • Hsu, C.C.1    Lien, J.C.2    Chang, C.W.3    Chang, C.H.4    Kuo, S.C.5    Huang, T.F.6
  • 21
    • 0034906265 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha enhances bradykinin-induced signal transduction via activation of Ras/Raf/MEK/MAPK in canine tracheal smooth muscle cells
    • Hsu, Y.M., C.T. Chiu, C.C. Wang, C.S. Chien, S.F. Luo, L.D. Hsiao, K.Y. Liang and C.M. Yang. Tumour necrosis factor-alpha enhances bradykinin-induced signal transduction via activation of Ras/Raf/MEK/MAPK in canine tracheal smooth muscle cells. Cell. Signal. 13: 633-643, 2001.
    • (2001) Cell. Signal. , vol.13 , pp. 633-643
    • Hsu, Y.M.1    Chiu, C.T.2    Wang, C.C.3    Chien, C.S.4    Luo, S.F.5    Hsiao, L.D.6    Liang, K.Y.7    Yang, C.M.8
  • 22
    • 79951734217 scopus 로고    scopus 로고
    • Extract of lotus leaf (Nelumbo nucifera) and its active constituent catechin with insulin secretagogue activity
    • Huang, C.F., Y.W. Chen, C.Y. Yang, H.Y. Lin, T.D. Way, W. Chiang and S.H. Liu. Extract of lotus leaf (Nelumbo nucifera) and its active constituent catechin with insulin secretagogue activity. J. Agric. Food. Chem. 59: 1087-1094, 2011.
    • (2011) J. Agric. Food. Chem. , vol.59 , pp. 1087-1094
    • Huang, C.F.1    Chen, Y.W.2    Yang, C.Y.3    Lin, H.Y.4    Way, T.D.5    Chiang, W.6    Liu, S.H.7
  • 24
    • 34547164540 scopus 로고    scopus 로고
    • The c-jun kinase/stress-activated pathway: Regulation, function and role in human disease
    • Johnson, G.L. and K. Nakamura. The c-jun kinase/stress-activated pathway: Regulation, function and role in human disease. Biochem. Biophys. Acta 1773: 1341-1348, 2007.
    • (2007) Biochem. Biophys. Acta , vol.1773 , pp. 1341-1348
    • Johnson, G.L.1    Nakamura, K.2
  • 26
    • 84863249806 scopus 로고    scopus 로고
    • Inhibitory Effect of Nelumbo nucifera (Gaertn) on the development of atopic dermatitis-like skin lesions in NC/Nga mice
    • Karki, R., M.A. Jung, K.J. Kim and D.W. Kim. Inhibitory Effect of Nelumbo nucifera (Gaertn) on the development of atopic dermatitis-like skin lesions in NC/Nga mice. Evid. Based Complement. Alternat. Med. 2012: 153568, 2012.
    • (2012) Evid. Based Complement. Alternat. Med. , vol.2012 , pp. 153568
    • Karki, R.1    Jung, M.A.2    Kim, K.J.3    Kim, D.W.4
  • 28
    • 33748316472 scopus 로고    scopus 로고
    • Functions of the MAPK family in vertebrate-development
    • Krens, S.F., H.P. Spaink and B.E. Snaar-Jagalska. Functions of the MAPK family in vertebrate-development. FEBS. Lett. 580: 4984-4990, 2006.
    • (2006) FEBS. Lett. , vol.580 , pp. 4984-4990
    • Krens, S.F.1    Spaink, H.P.2    Snaar-Jagalska, B.E.3
  • 29
    • 84872322092 scopus 로고    scopus 로고
    • Salidroside attenuates inflammatory responses by suppressing nuclear factor-kappaB and mitogen activated protein kinases activation in lipopolysaccharide-induced mastitis in mice
    • Li, D., Y. Fu, W. Zhang, G. Su, B. Liu, M. Guo, F. Li, D. Liang, Z. Liu, X. Zhang, Y. Cao, N. Zhang and Z. Yang. Salidroside attenuates inflammatory responses by suppressing nuclear factor-kappaB and mitogen activated protein kinases activation in lipopolysaccharide-induced mastitis in mice. Inflamm. Res. 62: 9-15, 2013.
    • (2013) Inflamm. Res. , vol.62 , pp. 9-15
    • Li, D.1    Fu, Y.2    Zhang, W.3    Su, G.4    Liu, B.5    Guo, M.6    Li, F.7    Liang, D.8    Liu, Z.9    Zhang, X.10    Cao, Y.11    Zhang, N.12    Yang, Z.13
  • 30
    • 68249122133 scopus 로고    scopus 로고
    • Antioxidative effect and active components from leaves of Lotus (Nelumbo nucifera)
    • Lin, H.Y., Y.H. Kuo, Y.L. Lin and W. Chiang. Antioxidative effect and active components from leaves of Lotus (Nelumbo nucifera). J. Agric. Food. Chem. 57: 6623-6629, 2009.
    • (2009) J. Agric. Food. Chem. , vol.57 , pp. 6623-6629
    • Lin, H.Y.1    Kuo, Y.H.2    Lin, Y.L.3    Chiang, W.4
  • 31
    • 2542484338 scopus 로고    scopus 로고
    • The extracts from Nelumbo Nucifera suppress cell cycle progression, cytokine genes expression, and cell proliferation in human peripheral blood mononuclear cells
    • Liu, C.P., W.J. Tsai, Y.L. Lin, J.F. Liao, C.F. Chen and Y.C. Kuo. The extracts from Nelumbo Nucifera suppress cell cycle progression, cytokine genes expression, and cell proliferation in human peripheral blood mononuclear cells. Life Sci. 75: 699-716, 2004.
    • (2004) Life Sci. , vol.75 , pp. 699-716
    • Liu, C.P.1    Tsai, W.J.2    Lin, Y.L.3    Liao, J.F.4    Chen, C.F.5    Kuo, Y.C.6
  • 32
    • 84866740088 scopus 로고    scopus 로고
    • Short-chain fatty acids suppress lipopolysaccharide-induced production of nitric oxide and proinflammatory cytokines through inhibition of NF-kappaB pathway in RAW264.7 cells
    • Liu, T., J. Li, Y. Liu, N. Xiao, H. Suo, K. Xie, C. Yang and C. Wu. Short-chain fatty acids suppress lipopolysaccharide-induced production of nitric oxide and proinflammatory cytokines through inhibition of NF-kappaB pathway in RAW264.7 cells. Inflammation 35: 1676-1684, 2012.
    • (2012) Inflammation , vol.35 , pp. 1676-1684
    • Liu, T.1    Li, J.2    Liu, Y.3    Xiao, N.4    Suo, H.5    Xie, K.6    Yang, C.7    Wu, C.8
  • 33
    • 79651473588 scopus 로고    scopus 로고
    • Arsenic induces pancreatic beta-cell apoptosis via the oxidative stress-regulated mitochondria-dependent and endoplasmic reticulum stress-triggered signaling pathways
    • Lu, T.H., C.C. Su, Y.W. Chen, C.Y. Yang, C.C. Wu, D.Z. Hung, C.H. Chen, P.W. Cheng, S.H. Liu and C.F. Huang. Arsenic induces pancreatic beta-cell apoptosis via the oxidative stress-regulated mitochondria-dependent and endoplasmic reticulum stress-triggered signaling pathways. Toxicol. Lett. 201: 15-26, 2011.
    • (2011) Toxicol. Lett. , vol.201 , pp. 15-26
    • Lu, T.H.1    Su, C.C.2    Chen, Y.W.3    Yang, C.Y.4    Wu, C.C.5    Hung, D.Z.6    Chen, C.H.7    Cheng, P.W.8    Liu, S.H.9    Huang, C.F.10
  • 34
    • 84887550914 scopus 로고    scopus 로고
    • Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated pathways
    • Lu, T.H., T.J. Tseng, C.C. Su, F.C. Tang, C.C. Yen, Y.Y. Liu, C.Y. Yang, C.C. Wu, K.L. Chen, D.Z. Hung and Y.W. Chen. Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated pathways. Toxicol. Lett. 224: 130-140, 2014.
    • (2014) Toxicol. Lett. , vol.224 , pp. 130-140
    • Lu, T.H.1    Tseng, T.J.2    Su, C.C.3    Tang, F.C.4    Yen, C.C.5    Liu, Y.Y.6    Yang, C.Y.7    Wu, C.C.8    Chen, K.L.9    Hung, D.Z.10    Chen, Y.W.11
  • 35
    • 0030694038 scopus 로고    scopus 로고
    • Biosynthesis and action of nitric oxide in mammalian cells
    • Mayer, B. and B. Hemmens. Biosynthesis and action of nitric oxide in mammalian cells. Trends. Biochem. Sci. 22: 477-481, 1997.
    • (1997) Trends. Biochem. Sci. , vol.22 , pp. 477-481
    • Mayer, B.1    Hemmens, B.2
  • 36
    • 39149129673 scopus 로고    scopus 로고
    • Emerging role of MAP kinase pathways as therapeutic targets in COPD
    • Mercer, B.A. and J.M. D'Armiento. Emerging role of MAP kinase pathways as therapeutic targets in COPD. Int. J. Chron. Obstruct. Pulmon. Dis. 1: 137-150, 2006.
    • (2006) Int. J. Chron. Obstruct. Pulmon. Dis. , vol.1 , pp. 137-150
    • Mercer, B.A.1    D'Armiento, J.M.2
  • 37
    • 84872387809 scopus 로고    scopus 로고
    • Activation of cannabinoid receptor 2 reduces inflammation in acute experimental pancreatitis via intra-acinar activation of p38 and MK2-dependent mechanisms
    • Michler, T., M. Storr, J. Kramer, S. Ochs, A. Malo, S. Reu, B. Goke and C. Schafer. Activation of cannabinoid receptor 2 reduces inflammation in acute experimental pancreatitis via intra-acinar activation of p38 and MK2-dependent mechanisms. Am. J. Physiol. Gastrointest. Liver Physiol. 304: G181-G192, 2013.
    • (2013) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.304
    • Michler, T.1    Storr, M.2    Kramer, J.3    Ochs, S.4    Malo, A.5    Reu, S.6    Goke, B.7    Schafer, C.8
  • 38
    • 4444333049 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases
    • Minghetti, L. Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases. J. Neuropathol. Exp. Neurol. 63: 901-910, 2004.
    • (2004) J. Neuropathol. Exp. Neurol. , vol.63 , pp. 901-910
    • Minghetti, L.1
  • 39
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada, S., R.M. Palmer and E.A. Higgs. Nitric oxide: Physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43: 109-142, 1991.
    • (1991) Pharmacol. Rev. , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 42
    • 84860498875 scopus 로고    scopus 로고
    • 7, 8-Dihy-droxyflavone exhibits anti-inflammatory properties by downregulating the NF-kappaB and MAPK signaling pathways in lipopolysaccharide- treated RAW264.7 Cells
    • Park, H.Y., G.Y. Kim, J.W. Hyun, H.J. Hwang, N.D. Kim, B.W. Kim and Y.H. Choi. 7, 8-Dihy-droxyflavone exhibits anti-inflammatory properties by downregulating the NF-kappaB and MAPK signaling pathways in lipopolysaccharide- treated RAW264.7 cells. Int. J. Mol. Med. 29: 1146-1152, 2012.
    • (2012) Int. J. Mol. Med. , vol.29 , pp. 1146-1152
    • Park, H.Y.1    Kim, G.Y.2    Hyun, J.W.3    Hwang, H.J.4    Kim, N.D.5    Kim, B.W.6    Choi, Y.H.7
  • 43
    • 84862180074 scopus 로고    scopus 로고
    • Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor
    • Qureshi, A.A., X.Q. Guan, J.C. Reis, C.J. Papasian, S. Jabre, D.C. Morrison and N. Qureshi. Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor. Lipids Health Dis. 11: 76, 2012.
    • (2012) Lipids Health Dis. , vol.11 , pp. 76
    • Qureshi, A.A.1    Guan, X.Q.2    Reis, J.C.3    Papasian, C.J.4    Jabre, S.5    Morrison, D.C.6    Qureshi, N.7
  • 44
    • 79955549267 scopus 로고    scopus 로고
    • IL-6 production is positively regulated by two distinct Src homology domain 2-containing tyrosine phosphatase-1 (SHP-1)-dependent CCAAT/enhancer-binding protein (3 and NF-KB pathways and an SHP-1-independent NF-KB pathway in lipopolysaccharide-stimulated bone marrow-derived macrophages
    • Rego, D., A. Kumar, L. Nilchi, K. Wright, S. Huang and M. Kozlowski. IL-6 production is positively regulated by two distinct Src homology domain 2-containing tyrosine phosphatase-1 (SHP-1)-dependent CCAAT/enhancer-binding protein (3 and NF-KB pathways and an SHP-1-independent NF-KB pathway in lipopolysaccharide-stimulated bone marrow-derived macrophages. J. Immuno. 186: 5443-5456, 2011.
    • (2011) J. Immuno. , vol.186 , pp. 5443-5456
    • Rego, D.1    Kumar, A.2    Nilchi, L.3    Wright, K.4    Huang, S.5    Kozlowski, M.6
  • 45
    • 0028180129 scopus 로고
    • Induction of cyclooxygenase-2 by interleukin-1 alpha. Evidence for post-transcriptional regulation
    • Ristimaki, A., S. Garfinkel, J. Wessendorf, T. Maciag and T. Hla. Induction of cyclooxygenase-2 by interleukin-1 alpha. Evidence for post-transcriptional regulation. J. Biol. Chem. 269: 11769-11775, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 11769-11775
    • Ristimaki, A.1    Garfinkel, S.2    Wessendorf, J.3    Maciag, T.4    Hla, T.5
  • 46
    • 39849098748 scopus 로고    scopus 로고
    • Role of the JNK signal transduction pathway in inflammatory bowel disease
    • Roy, P.K., F. Rashid, J. Bragg and J.A. Ibdah. Role of the JNK signal transduction pathway in inflammatory bowel disease. World J. Gastroenterol. 14: 200-202, 2008.
    • (2008) World J. Gastroenterol. , vol.14 , pp. 200-202
    • Roy, P.K.1    Rashid, F.2    Bragg, J.3    Ibdah, J.A.4
  • 48
    • 79953874256 scopus 로고    scopus 로고
    • High glucose induces enhanced expression of resistin in human U937 monocyte-like cell line by MAPK-and NF-KB-dependent mechanisms; The modulating effect of insulin
    • Stan, D., M. Calin, I. Manduteanu, M. Pirvulescu, A.M. Gan, E.D. Butoi, V. Simion and M. Simionescu. High glucose induces enhanced expression of resistin in human U937 monocyte-like cell line by MAPK-and NF-KB-dependent mechanisms; the modulating effect of insulin. Cell Tissue Res. 343: 379-387, 2011.
    • (2011) Cell Tissue Res. , vol.343 , pp. 379-387
    • Stan, D.1    Calin, M.2    Manduteanu, I.3    Pirvulescu, M.4    Gan, A.M.5    Butoi, E.D.6    Simion, V.7    Simionescu, M.8
  • 49
    • 77956440747 scopus 로고    scopus 로고
    • Eriobotryae folium extract suppresses LPS-induced iNOS and COX-2 expression by inhibition of NF-kappaB and MAPK activation in murine macrophages
    • Uto, T., N. Suangkaew, O. Morinaga, H. Kariyazono, S. Oiso and Y. Shoyama. Eriobotryae folium extract suppresses LPS-induced iNOS and COX-2 expression by inhibition of NF-kappaB and MAPK activation in murine macrophages. Am. J. Chin. Med. 38: 985-994, 2010.
    • (2010) Am. J. Chin. Med. , vol.38 , pp. 985-994
    • Uto, T.1    Suangkaew, N.2    Morinaga, O.3    Kariyazono, H.4    Oiso, S.5    Shoyama, Y.6
  • 50
    • 0027939931 scopus 로고
    • Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase
    • Xie, Q.W., Y. Kashiwabara and C. Nathan. Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase. J. Biol. Chem. 269: 4705-4708, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 4705-4708
    • Xie, Q.W.1    Kashiwabara, Y.2    Nathan, C.3
  • 51
    • 0034186090 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase and inflammatory diseases
    • Zamora, R., Y. Vodovotz and T.R. Billiar. Inducible nitric oxide synthase and inflammatory diseases. Mol. Med. 6: 347-373, 2000.
    • (2000) Mol. Med. , vol.6 , pp. 347-373
    • Zamora, R.1    Vodovotz, Y.2    Billiar, T.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.