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Volumn 9, Issue 5, 2014, Pages

Changes in gene expression associated with FTO overexpression in mice

Author keywords

[No Author keywords available]

Indexed keywords

6 N METHYLADENOSINE; MESSENGER RNA; FTO PROTEIN, MOUSE; LYASE; MIXED FUNCTION OXIDASE;

EID: 84901317984     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097162     Document Type: Article
Times cited : (26)

References (57)
  • 2
    • 85027911010 scopus 로고    scopus 로고
    • The bigger picture of FTO-the first GWAS-identified obesity gene
    • Loos RJ, Yeo GS (2013) The bigger picture of FTO-the first GWAS-identified obesity gene. Nat Rev Endocrinol.
    • (2013) Nat Rev Endocrinol
    • Loos, R.J.1    Yeo, G.S.2
  • 3
    • 77955981202 scopus 로고    scopus 로고
    • The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels
    • Berulava T, Horsthemke B (2010) The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels. Eur J Hum Genet 18: 1054-1056.
    • (2010) Eur J Hum Genet , vol.18 , pp. 1054-1056
    • Berulava, T.1    Horsthemke, B.2
  • 6
    • 78649512744 scopus 로고    scopus 로고
    • The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice
    • Gao X, Shin YH, Li M, Wang F, Tong Q, et al. (2010) The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice. PLoS One 5: e14005.
    • (2010) PLoS One , vol.5
    • Gao, X.1    Shin, Y.H.2    Li, M.3    Wang, F.4    Tong, Q.5
  • 7
    • 84873520661 scopus 로고    scopus 로고
    • Adult onset global loss of the Fto gene alters body composition and metabolism in the mouse
    • McMurray F, Church CD, Larder R, Nicholson G, Wells S, et al. (2012) Adult onset global loss of the Fto gene alters body composition and metabolism in the mouse. PLoS Genet.
    • (2012) PLoS Genet
    • McMurray, F.1    Church, C.D.2    Larder, R.3    Nicholson, G.4    Wells, S.5
  • 8
    • 70149100469 scopus 로고    scopus 로고
    • A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene
    • Church C, Lee S, Bagg EA, McTaggart JS, Deacon R, et al. (2009) A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene. PLoS Genet 5: e1000599.
    • (2009) PLoS Genet , vol.5
    • Church, C.1    Lee, S.2    Bagg, E.A.3    McTaggart, J.S.4    Deacon, R.5
  • 9
    • 78649459183 scopus 로고    scopus 로고
    • Overexpression of Fto leads to increased food intake and results in obesity
    • Church C, Moir L, McMurray F, Girard C, Banks GT, et al. (2010) Overexpression of Fto leads to increased food intake and results in obesity. Nat Genet 42: 1086-1092.
    • (2010) Nat Genet , vol.42 , pp. 1086-1092
    • Church, C.1    Moir, L.2    McMurray, F.3    Girard, C.4    Banks, G.T.5
  • 11
    • 54849381000 scopus 로고    scopus 로고
    • Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO
    • Jia G, Yang CG, Yang S, Jian X, Yi C, et al. (2008) Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO. FEBS Lett 582: 3313-3319.
    • (2008) FEBS Lett , vol.582 , pp. 3313-3319
    • Jia, G.1    Yang, C.G.2    Yang, S.3    Jian, X.4    Yi, C.5
  • 12
    • 81355146483 scopus 로고    scopus 로고
    • N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
    • Jia G, Fu Y, Zhao X, Dai Q, Zheng G, et al. (2011) N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol 7: 885-887.
    • (2011) Nat Chem Biol , vol.7 , pp. 885-887
    • Jia, G.1    Fu, Y.2    Zhao, X.3    Dai, Q.4    Zheng, G.5
  • 13
    • 0021022446 scopus 로고
    • 6A) in pre-mRNA are important for formation of late Simian virus 40 mRNAs
    • Finkel D, Groner Y (1983) Methylations of adenosine residues (m6A) in pre-mRNA are important for formation of late simian virus 40 mRNAs. Virology 131: 409-425. (Pubitemid 14175443)
    • (1983) Virology , vol.131 , Issue.2 , pp. 409-425
    • Finkel, D.1    Groner, Y.2
  • 14
    • 0020074714 scopus 로고
    • Accumulation of spliced avian retrovirus mRNA is inhibited in S-adenosylmethionine-depleted chicken embryo fibroblasts
    • Stoltzfus CM, Dane RW (1982) Accumulation of spliced avian retrovirus mRNA is inhibited in S-adenosylmethionine-depleted chicken embryo fibroblasts. J Virol 42: 918-931. (Pubitemid 12125637)
    • (1982) Journal of Virology , vol.42 , Issue.3 , pp. 918-931
    • Stoltzfus, C.M.1    Dane, R.W.2
  • 15
    • 0021398869 scopus 로고
    • Effect of undermethylation on mRNA cytoplasmic appearance and half-life
    • Camper SA, Albers RJ, Coward JK, Rottman FM (1984) Effect of undermethylation on mRNA cytoplasmic appearance and half-life. Mol Cell Biol 4: 538-543.
    • (1984) Mol Cell Biol , vol.4 , pp. 538-543
    • Camper, S.A.1    Albers, R.J.2    Coward, J.K.3    Rottman, F.M.4
  • 16
    • 0018715582 scopus 로고
    • Methylation of nuclear simian virus 40 RNAs
    • Aloni Y, Dhar R, Khoury G (1979) Methylation of nuclear simian virus 40 RNAs. J Virol 32: 52-60. (Pubitemid 10250012)
    • (1979) Journal of Virology , vol.32 , Issue.1 , pp. 52-60
    • Aloni, Y.1    Dhar, R.2    Khoury, G.3
  • 17
    • 0018657266 scopus 로고
    • 6-methyladenosine containing sequences in Simian Virus 40 RNA
    • Canaani D, Kahana C, Lavi S, Groner Y (1979) Identification and mapping of N6-methyladenosine containing sequences in simian virus 40 RNA. Nucleic Acids Res 6: 2879-2899. (Pubitemid 9211294)
    • (1979) Nucleic Acids Research , vol.6 , Issue.8 , pp. 2879-2899
    • Canaani, D.1    Kahana, C.2    Lavi, S.3    Groner, Y.4
  • 18
    • 0018793158 scopus 로고
    • N-6-methyl-adenosine in adenovirus type 2 nuclear RNA is conserved in the formation of messenger RNA
    • Chen-Kiang S, Nevins JR, Darnell JE Jr (1979) N-6-methyl-adenosine in adenovirus type 2 nuclear RNA is conserved in the formation of messenger RNA. J Mol Biol 135: 733-752.
    • (1979) J Mol Biol , vol.135 , pp. 733-752
    • Chen-Kiang, S.1    Nevins, J.R.2    Darnell Jr., J.E.3
  • 19
    • 0032872977 scopus 로고    scopus 로고
    • Inhibition of 6-methyladenine formation decreases the translation efficiency of dihydrofolate reductase transcripts
    • DOI 10.1016/S1357-2725(99)00041-2, PII S1357272599000412
    • Tuck MT, Wiehl PE, Pan T (1999) Inhibition of 6-methyladenine formation decreases the translation efficiency of dihydrofolate reductase transcripts. Int J Biochem Cell Biol 31: 837-851. (Pubitemid 29354080)
    • (1999) International Journal of Biochemistry and Cell Biology , vol.31 , Issue.8 , pp. 837-851
    • Tuck, M.T.1    Wiehl, P.E.2    Pan, T.3
  • 20
    • 84897110592 scopus 로고    scopus 로고
    • A METTL3-METTL14 complex mediates mammalian nuclear RNA N(6)-adenosine methylation
    • Liu J, Yue Y, Han D, Wang X, Fu Y, et al. (2014) A METTL3-METTL14 complex mediates mammalian nuclear RNA N(6)-adenosine methylation. Nat Chem Biol 10: 93-95.
    • (2014) Nat Chem Biol , vol.10 , pp. 93-95
    • Liu, J.1    Yue, Y.2    Han, D.3    Wang, X.4    Fu, Y.5
  • 21
    • 84893746230 scopus 로고    scopus 로고
    • Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase
    • Ping XL, Sun BF, Wang L, Xiao W, Yang X, et al. (2014) Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase. Cell Res 24: 177-189.
    • (2014) Cell Res , vol.24 , pp. 177-189
    • Ping, X.L.1    Sun, B.F.2    Wang, L.3    Xiao, W.4    Yang, X.5
  • 22
    • 84892372347 scopus 로고    scopus 로고
    • N6-methyladenosine-dependent regulation of messenger RNA stability
    • Wang X, Lu Z, Gomez A, Hon GC, Yue Y, et al. (2014) N6-methyladenosine- dependent regulation of messenger RNA stability. Nature 505: 117-120.
    • (2014) Nature , vol.505 , pp. 117-120
    • Wang, X.1    Lu, Z.2    Gomez, A.3    Hon, G.C.4    Yue, Y.5
  • 23
    • 84862649489 scopus 로고    scopus 로고
    • Comprehensive analysis of mRNA methylation reveals enrichment in 3 9 UTRs and near stop codons
    • Meyer KD, Saletore Y, Zumbo P, Elemento O, Mason CE, et al. (2012) Comprehensive analysis of mRNA methylation reveals enrichment in 3 9 UTRs and near stop codons. Cell 149: 1635-1646.
    • (2012) Cell , vol.149 , pp. 1635-1646
    • Meyer, K.D.1    Saletore, Y.2    Zumbo, P.3    Elemento, O.4    Mason, C.E.5
  • 25
    • 84880916638 scopus 로고    scopus 로고
    • The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry
    • Hess ME, Hess S, Meyer KD, Verhagen LA, Koch L, et al. (2013) The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry. Nat Neurosci 16: 1042-1048.
    • (2013) Nat Neurosci , vol.16 , pp. 1042-1048
    • Hess, M.E.1    Hess, S.2    Meyer, K.D.3    Verhagen, L.A.4    Koch, L.5
  • 26
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in realtime RT-PCR
    • Pfaffl MW (2001) A new mathematical model for relative quantification in realtime RT-PCR. Nucleic Acids Res 29: e45.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 27
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, et al. (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3: RESEARCH0034.
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5
  • 29
    • 84880773540 scopus 로고    scopus 로고
    • QTL analysis of dietary obesity in C57BL/6byj X 129P3/J F2 mice: Diet- and sex-dependent effects
    • Lin C, Theodorides ML, McDaniel AH, Tordoff MG, Zhang Q, et al. (2013) QTL analysis of dietary obesity in C57BL/6byj X 129P3/J F2 mice: diet- and sex-dependent effects. PLoS One 8: e68776.
    • (2013) PLoS One , vol.8
    • Lin, C.1    Theodorides, M.L.2    McDaniel, A.H.3    Tordoff, M.G.4    Zhang, Q.5
  • 31
    • 33845289819 scopus 로고    scopus 로고
    • Mechanisms underlying regulation of the expression and activities of the mammalian pyruvate dehydrogenase kinases
    • DOI 10.1080/13813450600935263, PII T6152666M0301757
    • Sugden MC, Holness MJ (2006) Mechanisms underlying regulation of the expression and activities of the mammalian pyruvate dehydrogenase kinases. Arch Physiol Biochem 112: 139-149. (Pubitemid 44871041)
    • (2006) Archives of Physiology and Biochemistry , vol.112 , Issue.3 , pp. 139-149
    • Sugden, M.C.1    Holness, M.J.2
  • 32
    • 66449096802 scopus 로고    scopus 로고
    • Identification of MUP1 as a regulator for glucose and lipid metabolism in mice
    • Zhou Y, Jiang L, Rui L (2009) Identification of MUP1 as a regulator for glucose and lipid metabolism in mice. J Biol Chem 284: 11152-11159.
    • (2009) J Biol Chem , vol.284 , pp. 11152-11159
    • Zhou, Y.1    Jiang, L.2    Rui, L.3
  • 33
    • 67649774119 scopus 로고    scopus 로고
    • Major urinary protein-1 increases energy expenditure and improves glucose intolerance through enhancing mitochondrial function in skeletal muscle of diabetic mice
    • Hui X, Zhu W, Wang Y, Lam KS, Zhang J, et al. (2009) Major urinary protein-1 increases energy expenditure and improves glucose intolerance through enhancing mitochondrial function in skeletal muscle of diabetic mice. J Biol Chem 284: 14050-14057.
    • (2009) J Biol Chem , vol.284 , pp. 14050-14057
    • Hui, X.1    Zhu, W.2    Wang, Y.3    Lam, K.S.4    Zhang, J.5
  • 34
    • 0028845877 scopus 로고
    • Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
    • Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, et al. (1995) Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1: 1155-1161.
    • (1995) Nat Med , vol.1 , pp. 1155-1161
    • Maffei, M.1    Halaas, J.2    Ravussin, E.3    Pratley, R.E.4    Lee, G.H.5
  • 35
    • 84857350273 scopus 로고    scopus 로고
    • Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance
    • Zong H, Armoni M, Harel C, Karnieli E, Pessin JE (2012) Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance. Am J Physiol Endocrinol Metab 302: E532-539.
    • (2012) Am J Physiol Endocrinol Metab , vol.302
    • Zong, H.1    Armoni, M.2    Harel, C.3    Karnieli, E.4    Pessin, J.E.5
  • 36
    • 33845193881 scopus 로고    scopus 로고
    • Obesity-induced increase of CYP2E1 activity and its effect on disposition kinetics of chlorzoxazone in Zucker rats
    • DOI 10.1016/j.bcp.2006.09.006, PII S0006295206005764
    • Khemawoot P, Yokogawa K, Shimada T, Miyamoto K (2007) Obesity-induced increase of CYP2E1 activity and its effect on disposition kinetics of chlorzoxazone in Zucker rats. Biochem Pharmacol 73: 155-162. (Pubitemid 44853929)
    • (2007) Biochemical Pharmacology , vol.73 , Issue.1 , pp. 155-162
    • Khemawoot, P.1    Yokogawa, K.2    Shimada, T.3    Miyamoto, K.-i.4
  • 37
    • 0037040253 scopus 로고    scopus 로고
    • PGC-1 functions as a transcriptional coactivator for the retinoid X receptors
    • DOI 10.1074/jbc.M109409200
    • Delerive P, Wu Y, Burris TP, Chin WW, Suen CS (2002) PGC-1 functions as a transcriptional coactivator for the retinoid X receptors. J Biol Chem 277: 3913-3917. (Pubitemid 34968643)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.6 , pp. 3913-3917
    • Delerive, P.1    Wu, Y.2    Burris, T.P.3    Chin, W.W.4    Suen, C.S.5
  • 39
    • 79957945033 scopus 로고    scopus 로고
    • Involvement of leptin receptor long isoform (LepRb)-STAT3 signaling pathway in brain fat mass- and obesity-associated (FTO) downregulation during energy restriction
    • Wang P, Yang FJ, Du H, Guan YF, Xu TY, et al. (2011) Involvement of leptin receptor long isoform (LepRb)-STAT3 signaling pathway in brain fat mass- and obesity-associated (FTO) downregulation during energy restriction. Mol Med 17: 523-532.
    • (2011) Mol Med , vol.17 , pp. 523-532
    • Wang, P.1    Yang, F.J.2    Du, H.3    Guan, Y.F.4    Xu, T.Y.5
  • 40
    • 84892415195 scopus 로고    scopus 로고
    • FTO contributes to hepatic metabolism regulation through regulation of leptin action and STAT3 signalling in liver
    • Bravard A, Vial G, Chauvin MA, Rouille Y, Bailleul B, et al. (2014) FTO contributes to hepatic metabolism regulation through regulation of leptin action and STAT3 signalling in liver. Cell Commun Signal 12: 4.
    • (2014) Cell Commun Signal , vol.12 , pp. 4
    • Bravard, A.1    Vial, G.2    Chauvin, M.A.3    Rouille, Y.4    Bailleul, B.5
  • 41
    • 84859023893 scopus 로고    scopus 로고
    • Adiponectin: Regulation of its production and its role in human diseases
    • Athens
    • Shehzad A, Iqbal W, Shehzad O, Lee YS (2012) Adiponectin: regulation of its production and its role in human diseases. Hormones (Athens) 11: 8-20.
    • (2012) Hormones , vol.11 , pp. 8-20
    • Shehzad, A.1    Iqbal, W.2    Shehzad, O.3    Lee, Y.S.4
  • 46
    • 0028787490 scopus 로고
    • A novel serum protein similar to C1q, produced exclusively in adipocytes
    • Scherer PE, Williams S, Fogliano M, Baldini G, Lodish HF (1995) A novel serum protein similar to C1q, produced exclusively in adipocytes. J Biol Chem 270: 26746-26749.
    • (1995) J Biol Chem , vol.270 , pp. 26746-26749
    • Scherer, P.E.1    Williams, S.2    Fogliano, M.3    Baldini, G.4    Lodish, H.F.5
  • 47
    • 42149097942 scopus 로고    scopus 로고
    • Upregulation of rat adipose tissue adiponectin gene expression by long-term but not by short-term food restriction
    • Turyn J, Korczynska J, Presler M, Stelmanska E, Goyke E, et al. (2008) Upregulation of rat adipose tissue adiponectin gene expression by long-term but not by short-term food restriction. Mol Cell Biochem 312: 185-191.
    • (2008) Mol Cell Biochem , vol.312 , pp. 185-191
    • Turyn, J.1    Korczynska, J.2    Presler, M.3    Stelmanska, E.4    Goyke, E.5
  • 49
    • 77956446435 scopus 로고    scopus 로고
    • Major urinary protein regulation of chemical communication and nutrient metabolism
    • Zhou Y, Rui L (2010) Major urinary protein regulation of chemical communication and nutrient metabolism. Vitam Horm 83: 151-163.
    • (2010) Vitam Horm , vol.83 , pp. 151-163
    • Zhou, Y.1    Rui, L.2
  • 50
    • 84878458278 scopus 로고    scopus 로고
    • Major urinary protein 5, a scent communication protein, is regulated by dietary restriction and subsequent re-feeding in mice
    • Giller K, Huebbe P, Doering F, Pallauf K, Rimbach G (2013) Major urinary protein 5, a scent communication protein, is regulated by dietary restriction and subsequent re-feeding in mice. Proc Biol Sci 280: 20130101.
    • (2013) Proc Biol Sci , vol.280 , pp. 20130101
    • Giller, K.1    Huebbe, P.2    Doering, F.3    Pallauf, K.4    Rimbach, G.5
  • 52
    • 52249112074 scopus 로고    scopus 로고
    • Differential screening identifies transcripts with depot-dependent expression in white adipose tissues
    • Wu Y, Kim JY, Zhou S, Smas CM (2008) Differential screening identifies transcripts with depot-dependent expression in white adipose tissues. BMC Genomics 9: 397.
    • (2008) BMC Genomics , vol.9 , pp. 397
    • Wu, Y.1    Kim, J.Y.2    Zhou, S.3    Smas, C.M.4
  • 54
    • 0026500754 scopus 로고
    • The formation of internal 6-methyladenine residues in eucaryotic messenger RNA
    • Tuck MT (1992) The formation of internal 6-methyladenine residues in eucaryotic messenger RNA. Int J Biochem 24: 379-386.
    • (1992) Int J Biochem , vol.24 , pp. 379-386
    • Tuck, M.T.1
  • 55
    • 0026463886 scopus 로고
    • Partial purification of a 6-methyladenine mRNA methyltransferase which modifies internal adenine residues
    • Tuck MT (1992) Partial purification of a 6-methyladenine mRNA methyltransferase which modifies internal adenine residues. Biochem J 288 (Pt 1): 233-240.
    • (1992) Biochem J , vol.288 , Issue.PART 1 , pp. 233-240
    • Tuck, M.T.1
  • 57
    • 78751542337 scopus 로고    scopus 로고
    • FTO is increased in muscle during type 2 diabetes, and its overexpression in myotubes alters insulin signaling, enhances lipogenesis and ROS production, and induces mitochondrial dysfunction
    • Bravard A, Lefai E, Meugnier E, Pesenti S, Disse E, et al. (2011) FTO is increased in muscle during type 2 diabetes, and its overexpression in myotubes alters insulin signaling, enhances lipogenesis and ROS production, and induces mitochondrial dysfunction. Diabetes 60: 258-268.
    • (2011) Diabetes , vol.60 , pp. 258-268
    • Bravard, A.1    Lefai, E.2    Meugnier, E.3    Pesenti, S.4    Disse, E.5


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