Epigenetic regulation of Smad2 and Smad3 by profilin-2 promotes lung cancer growth and metastasis

Nature Communications

Volumn 6, Issue , 2015, Pages

  Tang, Yun Neng ^a   Ding, Wei Qiao ^a   Guo, Xiao Jie ^a   Yuan, Xin Wang ^a   Wang, Dong Mei ^a   Song, Jian Guo ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN BINDING PROTEIN; CONNECTIVE TISSUE GROWTH FACTOR; HISTONE DEACETYLASE 1; PROFILIN 2; SMAD2 PROTEIN; SMAD3 PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN; CTGF PROTEIN, HUMAN; HDAC1 PROTEIN, HUMAN; PFN2 PROTEIN, HUMAN; PROFILIN; SMAD2 PROTEIN, HUMAN; SMAD3 PROTEIN, HUMAN; TGFB1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

CANCER; DRUG; GENE EXPRESSION; GENETICS; GROWTH; MOLECULAR ANALYSIS; PROTEIN; TUMOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; CANCER PATIENT; CANCER PROGNOSIS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EPIGENETICS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG METASTASIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION; ANIMAL; CANCER TRANSPLANTATION; CHROMATIN IMMUNOPRECIPITATION; CONFOCAL MICROSCOPY; EPITHELIAL MESENCHYMAL TRANSITION; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; HEK293 CELL LINE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LUNG TUMOR; METABOLISM; METASTASIS; NUDE MOUSE; PATHOLOGY; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR CELL LINE; TUMOR VOLUME;

ANIMALS; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; CONNECTIVE TISSUE GROWTH FACTOR; EPIGENESIS, GENETIC; EPITHELIAL-MESENCHYMAL TRANSITION; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HISTONE DEACETYLASE 1; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LUNG NEOPLASMS; MICE; MICE, NUDE; MICROSCOPY, CONFOCAL; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; PROFILINS; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TUMOR BURDEN; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84941595668     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9230     Document Type: Article

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