Profilin1 regulates PI(3,4)P2 and lamellipodin accumulation at the leading edge thus influencing motility of MDA-MB-231 cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 50, 2010, Pages 21547-21552

  Bae, Yong Ho ^a   Ding, Zhijie ^a   Das, Tuhin ^a   Wells, Alan ^a,b,c   Gertler, Frank ^d   Roy, Partha ^a,b  

^a University of Pittsburgh   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c Pittsburgh Veterans Afffairs Medical Center   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; LAMELLIPODIN; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROFILIN; UNCLASSIFIED DRUG; VASODILATOR STIMULATED PHOSPHOPROTEIN;

ARTICLE; BREAST CANCER; CANCER CELL; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN LOCALIZATION; PROTEIN TARGETING;

CARRIER PROTEINS; CELL ADHESION MOLECULES; CELL LINE, TUMOR; CELL MOVEMENT; HUMANS; MEMBRANE PROTEINS; MICROFILAMENT PROTEINS; PHOSPHATIDYLINOSITOLS; PHOSPHOPROTEINS; PROFILINS;

EID: 78650722061     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1002309107     Document Type: Article

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