-
1
-
-
84861205063
-
Cell-cell transmission enables HIV-1 to evade inhibition by potent CD4bs directed antibodies
-
I.A. Abela, L. Berlinger, M. Schanz, L. Reynell, H.F. Günthard, P. Rusert, and A. Trkola Cell-cell transmission enables HIV-1 to evade inhibition by potent CD4bs directed antibodies PLoS Pathog. 8 2012 e1002634
-
(2012)
PLoS Pathog.
, vol.8
, pp. e1002634
-
-
Abela, I.A.1
Berlinger, L.2
Schanz, M.3
Reynell, L.4
Günthard, H.F.5
Rusert, P.6
Trkola, A.7
-
2
-
-
76449098262
-
PHENIX: A comprehensive Python-based system for macromolecular structure solution
-
P.D. Adams, P.V. Afonine, G. Bunkóczi, V.B. Chen, I.W. Davis, N. Echols, J.J. Headd, L.W. Hung, G.J. Kapral, R.W. Grosse-Kunstleve, and et al. PHENIX: a comprehensive Python-based system for macromolecular structure solution Acta Crystallogr. D Biol. Crystallogr. 66 2010 213 221
-
(2010)
Acta Crystallogr. D Biol. Crystallogr.
, vol.66
, pp. 213-221
-
-
Adams, P.D.1
Afonine, P.V.2
Bunkóczi, G.3
Chen, V.B.4
Davis, I.W.5
Echols, N.6
Headd, J.J.7
Hung, L.W.8
Kapral, G.J.9
Grosse-Kunstleve, R.W.10
-
3
-
-
77952001983
-
Role of complex carbohydrates in human immunodeficiency virus type 1 infection and resistance to antibody neutralization
-
J.M. Binley, Y.E. Ban, E.T. Crooks, D. Eggink, K. Osawa, W.R. Schief, and R.W. Sanders Role of complex carbohydrates in human immunodeficiency virus type 1 infection and resistance to antibody neutralization J. Virol. 84 2010 5637 5655
-
(2010)
J. Virol.
, vol.84
, pp. 5637-5655
-
-
Binley, J.M.1
Ban, Y.E.2
Crooks, E.T.3
Eggink, D.4
Osawa, K.5
Schief, W.R.6
Sanders, R.W.7
-
4
-
-
84900467984
-
Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers
-
C. Blattner, J.H. Lee, K. Sliepen, R. Derking, E. Falkowska, A.T. de la Peña, A. Cupo, J.P. Julien, M. van Gils, P.S. Lee, and et al. Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers Immunity 40 2014 669 680
-
(2014)
Immunity
, vol.40
, pp. 669-680
-
-
Blattner, C.1
Lee, J.H.2
Sliepen, K.3
Derking, R.4
Falkowska, E.5
De La Peña, A.T.6
Cupo, A.7
Julien, J.P.8
Van Gils, M.9
Lee, P.S.10
-
5
-
-
0024575860
-
Designing CD4 immunoadhesins for AIDS therapy
-
D.J. Capon, S.M. Chamow, J. Mordenti, S.A. Marsters, T. Gregory, H. Mitsuya, R.A. Byrn, C. Lucas, F.M. Wurm, J.E. Groopman, and et al. Designing CD4 immunoadhesins for AIDS therapy Nature 337 1989 525 531
-
(1989)
Nature
, vol.337
, pp. 525-531
-
-
Capon, D.J.1
Chamow, S.M.2
Mordenti, J.3
Marsters, S.A.4
Gregory, T.5
Mitsuya, H.6
Byrn, R.A.7
Lucas, C.8
Wurm, F.M.9
Groopman, J.E.10
-
6
-
-
84928405730
-
Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117
-
M. Caskey, F. Klein, J.C. Lorenzi, M.S. Seaman, A.P. West Jr., N. Buckley, G. Kremer, L. Nogueira, M. Braunschweig, J.F. Scheid, and et al. Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117 Nature 522 2015 487 491
-
(2015)
Nature
, vol.522
, pp. 487-491
-
-
Caskey, M.1
Klein, F.2
Lorenzi, J.C.3
Seaman, M.S.4
West, A.P.5
Buckley, N.6
Kremer, G.7
Nogueira, L.8
Braunschweig, M.9
Scheid, J.F.10
-
7
-
-
84926453015
-
Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer
-
R. Derking, G. Ozorowski, K. Sliepen, A. Yasmeen, A. Cupo, J.L. Torres, J.P. Julien, J.H. Lee, T. van Montfort, S.W. de Taeye, and et al. Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer PLoS Pathog. 11 2015 e1004767
-
(2015)
PLoS Pathog.
, vol.11
, pp. e1004767
-
-
Derking, R.1
Ozorowski, G.2
Sliepen, K.3
Yasmeen, A.4
Cupo, A.5
Torres, J.L.6
Julien, J.P.7
Lee, J.H.8
Van Montfort, T.9
De Taeye, S.W.10
-
8
-
-
77951939875
-
Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity
-
R. Diskin, P.M. Marcovecchio, and P.J. Bjorkman Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity Nat. Struct. Mol. Biol. 17 2010 608 613
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 608-613
-
-
Diskin, R.1
Marcovecchio, P.M.2
Bjorkman, P.J.3
-
9
-
-
82755184131
-
Increasing the potency and breadth of an HIV antibody by using structure-based rational design
-
R. Diskin, J.F. Scheid, P.M. Marcovecchio, A.P. West Jr., F. Klein, H. Gao, P.N. Gnanapragasam, A. Abadir, M.S. Seaman, M.C. Nussenzweig, and P.J. Bjorkman Increasing the potency and breadth of an HIV antibody by using structure-based rational design Science 334 2011 1289 1293
-
(2011)
Science
, vol.334
, pp. 1289-1293
-
-
Diskin, R.1
Scheid, J.F.2
Marcovecchio, P.M.3
West, A.P.4
Klein, F.5
Gao, H.6
Gnanapragasam, P.N.7
Abadir, A.8
Seaman, M.S.9
Nussenzweig, M.C.10
Bjorkman, P.J.11
-
10
-
-
0025076063
-
Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase i
-
A.D. Elbein, J.E. Tropea, M. Mitchell, and G.P. Kaushal Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I J. Biol. Chem. 265 1990 15599 15605
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 15599-15605
-
-
Elbein, A.D.1
Tropea, J.E.2
Mitchell, M.3
Kaushal, G.P.4
-
12
-
-
84922224963
-
Intra-spike crosslinking overcomes antibody evasion by HIV-1
-
R.P. Galimidi, J.S. Klein, M.S. Politzer, S. Bai, M.S. Seaman, M.C. Nussenzweig, A.P. West Jr., and P.J. Bjorkman Intra-spike crosslinking overcomes antibody evasion by HIV-1 Cell 160 2015 433 446
-
(2015)
Cell
, vol.160
, pp. 433-446
-
-
Galimidi, R.P.1
Klein, J.S.2
Politzer, M.S.3
Bai, S.4
Seaman, M.S.5
Nussenzweig, M.C.6
West, A.P.7
Bjorkman, P.J.8
-
13
-
-
79961184231
-
Characterization of glycosylation profiles of HIV-1 transmitted/founder envelopes by mass spectrometry
-
E.P. Go, G. Hewawasam, H.X. Liao, H. Chen, L.H. Ping, J.A. Anderson, D.C. Hua, B.F. Haynes, and H. Desaire Characterization of glycosylation profiles of HIV-1 transmitted/founder envelopes by mass spectrometry J. Virol. 85 2011 8270 8284
-
(2011)
J. Virol.
, vol.85
, pp. 8270-8284
-
-
Go, E.P.1
Hewawasam, G.2
Liao, H.X.3
Chen, H.4
Ping, L.H.5
Anderson, J.A.6
Hua, D.C.7
Haynes, B.F.8
Desaire, H.9
-
14
-
-
84923164032
-
Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env
-
M. Guttman, A. Cupo, J.P. Julien, R.W. Sanders, I.A. Wilson, J.P. Moore, and K.K. Lee Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env Nat. Commun. 6 2015 6144
-
(2015)
Nat. Commun.
, vol.6
, pp. 6144
-
-
Guttman, M.1
Cupo, A.2
Julien, J.P.3
Sanders, R.W.4
Wilson, I.A.5
Moore, J.P.6
Lee, K.K.7
-
15
-
-
79960974710
-
Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures
-
A. Harris, M.J. Borgnia, D. Shi, A. Bartesaghi, H. He, R. Pejchal, Y.K. Kang, R. Depetris, A.J. Marozsan, R.W. Sanders, and et al. Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures Proc. Natl. Acad. Sci. USA 108 2011 11440 11445
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 11440-11445
-
-
Harris, A.1
Borgnia, M.J.2
Shi, D.3
Bartesaghi, A.4
He, H.5
Pejchal, R.6
Kang, Y.K.7
Depetris, R.8
Marozsan, A.J.9
Sanders, R.W.10
-
16
-
-
84885338257
-
HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice
-
J.A. Horwitz, A. Halper-Stromberg, H. Mouquet, A.D. Gitlin, A. Tretiakova, T.R. Eisenreich, M. Malbec, S. Gravemann, E. Billerbeck, M. Dorner, and et al. HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice Proc. Natl. Acad. Sci. USA 110 2013 16538 16543
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 16538-16543
-
-
Horwitz, J.A.1
Halper-Stromberg, A.2
Mouquet, H.3
Gitlin, A.D.4
Tretiakova, A.5
Eisenreich, T.R.6
Malbec, M.7
Gravemann, S.8
Billerbeck, E.9
Dorner, M.10
-
17
-
-
84921607768
-
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface
-
J. Huang, B.H. Kang, M. Pancera, J.H. Lee, T. Tong, Y. Feng, H. Imamichi, I.S. Georgiev, G.Y. Chuang, A. Druz, and et al. Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface Nature 515 2014 138 142
-
(2014)
Nature
, vol.515
, pp. 138-142
-
-
Huang, J.1
Kang, B.H.2
Pancera, M.3
Lee, J.H.4
Tong, T.5
Feng, Y.6
Imamichi, H.7
Georgiev, I.S.8
Chuang, G.Y.9
Druz, A.10
-
19
-
-
84890858459
-
Crystal structure of a soluble cleaved HIV-1 envelope trimer
-
J.P. Julien, A. Cupo, D. Sok, R.L. Stanfield, D. Lyumkis, M.C. Deller, P.J. Klasse, D.R. Burton, R.W. Sanders, J.P. Moore, and et al. Crystal structure of a soluble cleaved HIV-1 envelope trimer Science 342 2013 1477 1483
-
(2013)
Science
, vol.342
, pp. 1477-1483
-
-
Julien, J.P.1
Cupo, A.2
Sok, D.3
Stanfield, R.L.4
Lyumkis, D.5
Deller, M.C.6
Klasse, P.J.7
Burton, D.R.8
Sanders, R.W.9
Moore, J.P.10
-
20
-
-
84878519611
-
Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans
-
J.P. Julien, D. Sok, R. Khayat, J.H. Lee, K.J. Doores, L.M. Walker, A. Ramos, D.C. Diwanji, R. Pejchal, A. Cupo, and et al. Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans PLoS Pathog. 9 2013 e1003342
-
(2013)
PLoS Pathog.
, vol.9
, pp. e1003342
-
-
Julien, J.P.1
Sok, D.2
Khayat, R.3
Lee, J.H.4
Doores, K.J.5
Walker, L.M.6
Ramos, A.7
Diwanji, D.C.8
Pejchal, R.9
Cupo, A.10
-
21
-
-
76449106188
-
Integration, scaling, space-group assignment and post-refinement
-
W. Kabsch Integration, scaling, space-group assignment and post-refinement Acta Crystallogr. D Biol. Crystallogr. 66 2010 133 144
-
(2010)
Acta Crystallogr. D Biol. Crystallogr.
, vol.66
, pp. 133-144
-
-
Kabsch, W.1
-
22
-
-
84870562234
-
HIV therapy by a combination of broadly neutralizing antibodies in humanized mice
-
F. Klein, A. Halper-Stromberg, J.A. Horwitz, H. Gruell, J.F. Scheid, S. Bournazos, H. Mouquet, L.A. Spatz, R. Diskin, A. Abadir, and et al. HIV therapy by a combination of broadly neutralizing antibodies in humanized mice Nature 492 2012 118 122
-
(2012)
Nature
, vol.492
, pp. 118-122
-
-
Klein, F.1
Halper-Stromberg, A.2
Horwitz, J.A.3
Gruell, H.4
Scheid, J.F.5
Bournazos, S.6
Mouquet, H.7
Spatz, L.A.8
Diskin, R.9
Abadir, A.10
-
23
-
-
0029879295
-
Computer visualization of three-dimensional image data using IMOD
-
J.R. Kremer, D.N. Mastronarde, and J.R. McIntosh Computer visualization of three-dimensional image data using IMOD J. Struct. Biol. 116 1996 71 76
-
(1996)
J. Struct. Biol.
, vol.116
, pp. 71-76
-
-
Kremer, J.R.1
Mastronarde, D.N.2
McIntosh, J.R.3
-
24
-
-
84859561617
-
Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops
-
Y.D. Kwon, A. Finzi, X. Wu, C. Dogo-Isonagie, L.K. Lee, L.R. Moore, S.D. Schmidt, J. Stuckey, Y. Yang, T. Zhou, and et al. Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops Proc. Natl. Acad. Sci. USA 109 2012 5663 5668
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 5663-5668
-
-
Kwon, Y.D.1
Finzi, A.2
Wu, X.3
Dogo-Isonagie, C.4
Lee, L.K.5
Moore, L.R.6
Schmidt, S.D.7
Stuckey, J.8
Yang, Y.9
Zhou, T.10
-
25
-
-
84936846696
-
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
-
Y. Do Kwon, M. Pancera, P. Acharya, I.S. Georgiev, E.T. Crooks, J. Gorman, M.G. Joyce, M. Guttman, X. Ma, S. Narpala, and et al. Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env Nat. Struct. Mol. Biol. 22 2015 522 531
-
(2015)
Nat. Struct. Mol. Biol.
, vol.22
, pp. 522-531
-
-
Do Kwon, Y.1
Pancera, M.2
Acharya, P.3
Georgiev, I.S.4
Crooks, E.T.5
Gorman, J.6
Joyce, M.G.7
Guttman, M.8
Ma, X.9
Narpala, S.10
-
26
-
-
51349162563
-
Molecular architecture of native HIV-1 gp120 trimers
-
J. Liu, A. Bartesaghi, M.J. Borgnia, G. Sapiro, and S. Subramaniam Molecular architecture of native HIV-1 gp120 trimers Nature 455 2008 109 113
-
(2008)
Nature
, vol.455
, pp. 109-113
-
-
Liu, J.1
Bartesaghi, A.2
Borgnia, M.J.3
Sapiro, G.4
Subramaniam, S.5
-
27
-
-
84890859441
-
Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer
-
D. Lyumkis, J.P. Julien, N. de Val, A. Cupo, C.S. Potter, P.J. Klasse, D.R. Burton, R.W. Sanders, J.P. Moore, B. Carragher, and et al. Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer Science 342 2013 1484 1490
-
(2013)
Science
, vol.342
, pp. 1484-1490
-
-
Lyumkis, D.1
Julien, J.P.2
De Val, N.3
Cupo, A.4
Potter, C.S.5
Klasse, P.J.6
Burton, D.R.7
Sanders, R.W.8
Moore, J.P.9
Carragher, B.10
-
28
-
-
83455254775
-
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
-
J.S. McLellan, M. Pancera, C. Carrico, J. Gorman, J.P. Julien, R. Khayat, R. Louder, R. Pejchal, M. Sastry, K. Dai, and et al. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 Nature 480 2011 336 343
-
(2011)
Nature
, vol.480
, pp. 336-343
-
-
McLellan, J.S.1
Pancera, M.2
Carrico, C.3
Gorman, J.4
Julien, J.P.5
Khayat, R.6
Louder, R.7
Pejchal, R.8
Sastry, M.9
Dai, K.10
-
30
-
-
84869831194
-
Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
-
H. Mouquet, L. Scharf, Z. Euler, Y. Liu, C. Eden, J.F. Scheid, A. Halper-Stromberg, P.N. Gnanapragasam, D.I. Spencer, M.S. Seaman, and et al. Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies Proc. Natl. Acad. Sci. USA 109 2012 E3268 E3277
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. E3268-E3277
-
-
Mouquet, H.1
Scharf, L.2
Euler, Z.3
Liu, Y.4
Eden, C.5
Scheid, J.F.6
Halper-Stromberg, A.7
Gnanapragasam, P.N.8
Spencer, D.I.9
Seaman, M.S.10
-
31
-
-
84909606387
-
Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions
-
J.B. Munro, J. Gorman, X. Ma, Z. Zhou, J. Arthos, D.R. Burton, W.C. Koff, J.R. Courter, A.B. Smith 3rd, P.D. Kwong, and et al. Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions Science 346 2014 759 763
-
(2014)
Science
, vol.346
, pp. 759-763
-
-
Munro, J.B.1
Gorman, J.2
Ma, X.3
Zhou, Z.4
Arthos, J.5
Burton, D.R.6
Koff, W.C.7
Courter, J.R.8
Smith, A.B.9
Kwong, P.D.10
-
32
-
-
33747598723
-
The molecular architecture of axonemes revealed by cryoelectron tomography
-
D. Nicastro, C. Schwartz, J. Pierson, R. Gaudette, M.E. Porter, and J.R. McIntosh The molecular architecture of axonemes revealed by cryoelectron tomography Science 313 2006 944 948
-
(2006)
Science
, vol.313
, pp. 944-948
-
-
Nicastro, D.1
Schwartz, C.2
Pierson, J.3
Gaudette, R.4
Porter, M.E.5
McIntosh, J.R.6
-
33
-
-
84909640954
-
Structure and immune recognition of trimeric pre-fusion HIV-1 Env
-
M. Pancera, T. Zhou, A. Druz, I.S. Georgiev, C. Soto, J. Gorman, J. Huang, P. Acharya, G.Y. Chuang, G. Ofek, and et al. Structure and immune recognition of trimeric pre-fusion HIV-1 Env Nature 514 2014 455 461
-
(2014)
Nature
, vol.514
, pp. 455-461
-
-
Pancera, M.1
Zhou, T.2
Druz, A.3
Georgiev, I.S.4
Soto, C.5
Gorman, J.6
Huang, J.7
Acharya, P.8
Chuang, G.Y.9
Ofek, G.10
-
34
-
-
82255179322
-
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield
-
R. Pejchal, K.J. Doores, L.M. Walker, R. Khayat, P.S. Huang, S.K. Wang, R.L. Stanfield, J.P. Julien, A. Ramos, M. Crispin, and et al. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield Science 334 2011 1097 1103
-
(2011)
Science
, vol.334
, pp. 1097-1103
-
-
Pejchal, R.1
Doores, K.J.2
Walker, L.M.3
Khayat, R.4
Huang, P.S.5
Wang, S.K.6
Stanfield, R.L.7
Julien, J.P.8
Ramos, A.9
Crispin, M.10
-
35
-
-
4444221565
-
UCSF Chimera - A visualization system for exploratory research and analysis
-
E.F. Pettersen, T.D. Goddard, C.C. Huang, G.S. Couch, D.M. Greenblatt, E.C. Meng, and T.E. Ferrin UCSF Chimera - a visualization system for exploratory research and analysis J. Comput. Chem. 25 2004 1605 1612
-
(2004)
J. Comput. Chem.
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.F.1
Goddard, T.D.2
Huang, C.C.3
Couch, G.S.4
Greenblatt, D.M.5
Meng, E.C.6
Ferrin, T.E.7
-
36
-
-
84923172318
-
A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene
-
P. Pugach, G. Ozorowski, A. Cupo, R. Ringe, A. Yasmeen, N. de Val, R. Derking, H.J. Kim, J. Korzun, M. Golabek, and et al. A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene J. Virol. 89 2015 3380 3395
-
(2015)
J. Virol.
, vol.89
, pp. 3380-3395
-
-
Pugach, P.1
Ozorowski, G.2
Cupo, A.3
Ringe, R.4
Yasmeen, A.5
De Val, N.6
Derking, R.7
Kim, H.J.8
Korzun, J.9
Golabek, M.10
-
37
-
-
84884678235
-
A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies
-
R.W. Sanders, R. Derking, A. Cupo, J.P. Julien, A. Yasmeen, N. de Val, H.J. Kim, C. Blattner, A.T. de la Peña, J. Korzun, and et al. A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies PLoS Pathog. 9 2013 e1003618
-
(2013)
PLoS Pathog.
, vol.9
, pp. e1003618
-
-
Sanders, R.W.1
Derking, R.2
Cupo, A.3
Julien, J.P.4
Yasmeen, A.5
De Val, N.6
Kim, H.J.7
Blattner, C.8
De La Peña, A.T.9
Korzun, J.10
-
38
-
-
84899909771
-
Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike
-
L. Scharf, J.F. Scheid, J.H. Lee, A.P. West Jr., C. Chen, H. Gao, P.N. Gnanapragasam, R. Mares, M.S. Seaman, A.B. Ward, and et al. Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike Cell Rep. 7 2014 785 795
-
(2014)
Cell Rep.
, vol.7
, pp. 785-795
-
-
Scharf, L.1
Scheid, J.F.2
Lee, J.H.3
West, A.P.4
Chen, C.5
Gao, H.6
Gnanapragasam, P.N.7
Mares, R.8
Seaman, M.S.9
Ward, A.B.10
-
39
-
-
80052925616
-
Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding
-
J.F. Scheid, H. Mouquet, B. Ueberheide, R. Diskin, F. Klein, T.Y. Oliveira, J. Pietzsch, D. Fenyo, A. Abadir, K. Velinzon, and et al. Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding Science 333 2011 1633 1637
-
(2011)
Science
, vol.333
, pp. 1633-1637
-
-
Scheid, J.F.1
Mouquet, H.2
Ueberheide, B.3
Diskin, R.4
Klein, F.5
Oliveira, T.Y.6
Pietzsch, J.7
Fenyo, D.8
Abadir, A.9
Velinzon, K.10
-
40
-
-
84868444740
-
RELION: Implementation of a Bayesian approach to cryo-EM structure determination
-
S.H. Scheres RELION: implementation of a Bayesian approach to cryo-EM structure determination J. Struct. Biol. 180 2012 519 530
-
(2012)
J. Struct. Biol.
, vol.180
, pp. 519-530
-
-
Scheres, S.H.1
-
41
-
-
84866078359
-
Prevention of overfitting in cryo-EM structure determination
-
S.H. Scheres, and S. Chen Prevention of overfitting in cryo-EM structure determination Nat. Methods 9 2012 853 854
-
(2012)
Nat. Methods
, vol.9
, pp. 853-854
-
-
Scheres, S.H.1
Chen, S.2
-
42
-
-
0031902829
-
CD4-Induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: Consequences for virus entry and neutralization
-
N. Sullivan, Y. Sun, Q. Sattentau, M. Thali, D. Wu, G. Denisova, J. Gershoni, J. Robinson, J. Moore, and J. Sodroski CD4-Induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: consequences for virus entry and neutralization J. Virol. 72 1998 4694 4703
-
(1998)
J. Virol.
, vol.72
, pp. 4694-4703
-
-
Sullivan, N.1
Sun, Y.2
Sattentau, Q.3
Thali, M.4
Wu, D.5
Denisova, G.6
Gershoni, J.7
Robinson, J.8
Moore, J.9
Sodroski, J.10
-
43
-
-
33845332754
-
EMAN2: An extensible image processing suite for electron microscopy
-
G. Tang, L. Peng, P.R. Baldwin, D.S. Mann, W. Jiang, I. Rees, and S.J. Ludtke EMAN2: an extensible image processing suite for electron microscopy J. Struct. Biol. 157 2007 38 46
-
(2007)
J. Struct. Biol.
, vol.157
, pp. 38-46
-
-
Tang, G.1
Peng, L.2
Baldwin, P.R.3
Mann, D.S.4
Jiang, W.5
Rees, I.6
Ludtke, S.J.7
-
44
-
-
84864603281
-
Structural mechanism of trimeric HIV-1 envelope glycoprotein activation
-
E.E. Tran, M.J. Borgnia, O. Kuybeda, D.M. Schauder, A. Bartesaghi, G.A. Frank, G. Sapiro, J.L. Milne, and S. Subramaniam Structural mechanism of trimeric HIV-1 envelope glycoprotein activation PLoS Pathog. 8 2012 e1002797
-
(2012)
PLoS Pathog.
, vol.8
, pp. e1002797
-
-
Tran, E.E.1
Borgnia, M.J.2
Kuybeda, O.3
Schauder, D.M.4
Bartesaghi, A.5
Frank, G.A.6
Sapiro, G.7
Milne, J.L.8
Subramaniam, S.9
-
45
-
-
84879538530
-
Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues
-
A.P. West Jr., L. Scharf, J. Horwitz, F. Klein, M.C. Nussenzweig, and P.J. Bjorkman Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues Proc. Natl. Acad. Sci. USA 110 2013 10598 10603
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 10598-10603
-
-
West, A.P.1
Scharf, L.2
Horwitz, J.3
Klein, F.4
Nussenzweig, M.C.5
Bjorkman, P.J.6
-
46
-
-
84894173514
-
Structural insights on the role of antibodies in HIV-1 vaccine and therapy
-
A.P. West Jr., L. Scharf, J.F. Scheid, F. Klein, P.J. Bjorkman, and M.C. Nussenzweig Structural insights on the role of antibodies in HIV-1 vaccine and therapy Cell 156 2014 633 648
-
(2014)
Cell
, vol.156
, pp. 633-648
-
-
West, A.P.1
Scharf, L.2
Scheid, J.F.3
Klein, F.4
Bjorkman, P.J.5
Nussenzweig, M.C.6
-
47
-
-
78651241895
-
Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: Strain-dependent variation in quaternary structure
-
T.A. White, A. Bartesaghi, M.J. Borgnia, J.R. Meyerson, M.J. de la Cruz, J.W. Bess, R. Nandwani, J.A. Hoxie, J.D. Lifson, J.L. Milne, and S. Subramaniam Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure PLoS Pathog. 6 2010 e1001249
-
(2010)
PLoS Pathog.
, vol.6
, pp. e1001249
-
-
White, T.A.1
Bartesaghi, A.2
Borgnia, M.J.3
Meyerson, J.R.4
De La Cruz, M.J.5
Bess, J.W.6
Nandwani, R.7
Hoxie, J.A.8
Lifson, J.D.9
Milne, J.L.10
Subramaniam, S.11
-
48
-
-
81255213876
-
Three-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomography
-
T.A. White, A. Bartesaghi, M.J. Borgnia, M.J. de la Cruz, R. Nandwani, J.A. Hoxie, J.W. Bess, J.D. Lifson, J.L. Milne, and S. Subramaniam Three-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomography J. Virol. 85 2011 12114 12123
-
(2011)
J. Virol.
, vol.85
, pp. 12114-12123
-
-
White, T.A.1
Bartesaghi, A.2
Borgnia, M.J.3
De La Cruz, M.J.4
Nandwani, R.5
Hoxie, J.A.6
Bess, J.W.7
Lifson, J.D.8
Milne, J.L.9
Subramaniam, S.10
-
49
-
-
0036436313
-
Characterization of CD4-induced epitopes on the HIV type 1 gp120 envelope glycoprotein recognized by neutralizing human monoclonal antibodies
-
S.H. Xiang, N. Doka, R.K. Choudhary, J. Sodroski, and J.E. Robinson Characterization of CD4-induced epitopes on the HIV type 1 gp120 envelope glycoprotein recognized by neutralizing human monoclonal antibodies AIDS Res. Hum. Retroviruses 18 2002 1207 1217
-
(2002)
AIDS Res. Hum. Retroviruses
, vol.18
, pp. 1207-1217
-
-
Xiang, S.H.1
Doka, N.2
Choudhary, R.K.3
Sodroski, J.4
Robinson, J.E.5
-
50
-
-
33845319257
-
UCSF tomography: An integrated software suite for real-time electron microscopic tomographic data collection, alignment, and reconstruction
-
S.Q. Zheng, B. Keszthelyi, E. Branlund, J.M. Lyle, M.B. Braunfeld, J.W. Sedat, and D.A. Agard UCSF tomography: an integrated software suite for real-time electron microscopic tomographic data collection, alignment, and reconstruction J. Struct. Biol. 157 2007 138 147
-
(2007)
J. Struct. Biol.
, vol.157
, pp. 138-147
-
-
Zheng, S.Q.1
Keszthelyi, B.2
Branlund, E.3
Lyle, J.M.4
Braunfeld, M.B.5
Sedat, J.W.6
Agard, D.A.7
|