Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions

Science

Volumn 346, Issue 6210, 2014, Pages 759-763

  Munro, James B ^a,h   Gorman, Jason ^b   Ma, Xiaochu ^a   Zhou, Zhou ^c   Arthos, James ^b   Burton, Dennis R ^d,e   Koff, Wayne C ^f   Courter, Joel R ^g,i   Smith, Amos B ^g   Kwong, Peter D ^b   Blanchard, Scott C ^c   Mothes, Walther ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^f INTERNATIONAL AIDS VACCINE INITIATIVE   (United States)

^g UNIVERSITY OF PENNSYLVANIA   (United States)

^h TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ Experimental Station   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GLYCOPROTEIN GP 120; LIGAND; NEUTRALIZING ANTIBODY;

ANTIBODY; CHEMICAL BINDING; CYTOLOGY; FLUORESCENCE SPECTROSCOPY; IMMUNE RESPONSE; LIGAND; NEUTRALIZATION; PROTEIN; VIRUS;

ANTIGEN BINDING; ARTICLE; CONFORMATIONAL TRANSITION; FLUORESCENCE RESONANCE ENERGY TRANSFER; HOST CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE EVASION; NONHUMAN; SURFACE PROPERTY; VIRION; VIRUS ENTRY; VIRUS ENVELOPE; VIRUS ISOLATION; VIRUS NEUTRALIZATION; CHEMICAL MODEL; CHEMISTRY; HUMAN; IMMUNOLOGY; MOLECULAR IMAGING; PROCEDURES; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ANTIBODIES, NEUTRALIZING; ANTIGENS, CD4; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; IMMUNE EVASION; LIGANDS; MODELS, CHEMICAL; MOLECULAR IMAGING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; VIRION;

EID: 84909606387     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1254426     Document Type: Article

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