Curcumin suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock

Molecular Nutrition and Food Research

Volumn 59, Issue 11, 2015, Pages 2132-2142

  Gong, Zizhen ^a,b   Zhou, Jiefei ^a,b   Li, Hui ^c   Gao, Yanhong ^a   Xu, Congfeng ^a   Zhao, Shengnan ^a,b   Chen, Yingwei ^a,b   Cai, Wei ^a,b   Wu, Jin ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Key Laboratory of Nutrition and Metabolism   (China)

^c Institute of Health Sciences   (China)

Author keywords

Anti inflammation; Curcumin; IL 1 ; Inflammasome; MAPK

Indexed keywords

ANTIINFLAMMATORY AGENT; CRYOPYRIN; CURCUMIN; HIGH MOBILITY GROUP B1 PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE; NLRP3 PROTEIN, MOUSE; POTASSIUM; REACTIVE OXYGEN METABOLITE;

ANIMAL; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; LYSOSOME; METABOLISM; MOUSE; PHYSIOLOGY; SECRETION (PROCESS); SHOCK, SEPTIC; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CASPASE 1; CELLS, CULTURED; CURCUMIN; HMGB1 PROTEIN; INFLAMMASOMES; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; LYSOSOMES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; POTASSIUM; REACTIVE OXYGEN SPECIES; SHOCK, SEPTIC;

EID: 84940905668     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201500316     Document Type: Article

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