Activated IGF-1R inhibits hyperglycemia-induced DNA damage and promotes DNA repair by homologous recombination

American Journal of Physiology - Renal Physiology

Volumn 289, Issue 5 58-5, 2005, Pages

  Yang, Shuo ^b   Chintapalli, Janaki ^b   Sodagum, Lakshmi ^a   Baskin, Stuart ^a   Malhotra, Ashwani ^a   Reiss, Krzysztof ^b   Meggs, Leonard G ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b TEMPLE UNIVERSITY   (United States)

Author keywords

Danger signal; DNA double strand breaks; Genotoxicity; Rad51; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; GENOMIC DNA; GLUCOSE; RAD51 PROTEIN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELLULAR DISTRIBUTION; COMET ASSAY; DIABETIC NEPHROPATHY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; GENOTOXICITY; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IMMUNOBLOTTING; MESANGIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 24744444176     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00094.2005     Document Type: Article

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