Extended longevity and insulin signaling in adipose tissue

Experimental Gerontology

Volumn 40, Issue 11, 2005, Pages 878-883

  Klöting, Nora ^b   Blüher, Matthias ^a,b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Aipose tissue; Animal models; dFOXO; FIRKO; Insulin signaling; Longevity; SIRT1

Indexed keywords

FATTY ACID; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INSULIN RECEPTOR; LEPTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SILENT INFORMATION REGULATOR PROTEIN 2; SIRTUIN; SOMATOMEDIN C; TRANSCRIPTION FACTOR FOXO; TRIACYLGLYCEROL;

ADIPOSE TISSUE; AGING; ATHEROSCLEROSIS; BODY FAT; BODY MASS; CAENORHABDITIS ELEGANS; CALORIC RESTRICTION; DROSOPHILA; DROSOPHILA MELANOGASTER; FAT CONTENT; FOOD INTAKE; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIFESPAN; LONGEVITY; METABOLIC DISORDER; MOUSE STRAIN; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; ORTHOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SACCHAROMYCES CEREVISIAE; SHORT SURVEY; SIGNAL TRANSDUCTION;

ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; CAENORHABDITIS ELEGANS; CALORIC RESTRICTION; DROSOPHILA MELANOGASTER; HUMANS; INSULIN; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR I; LIVER; LONGEVITY; MICE; RATS; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION;

ANIMALIA; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; MAMMALIA; SACCHAROMYCES CEREVISIAE;

EID: 27544460718     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2005.07.004     Document Type: Short Survey

References (37)

1. E.D. Abel, O. Peroni, J.K. Kim, Y.B. Kim, O. Boss, E. Hadro, T. Minnemann, G.I. Shulman, and B.B. Kahn Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver Nature 409 2001 729 733
2. D. Accili, J. Drago, E.J. Lee, M.D. Johnson, M.H. Cool, P. Salvatore, L.D. Asico, P.A. Jose, S.I. Taylor, and H. Westphal Early neonatal death in mice homozygous for a null allele of the insulin receptor gene Nat. Genet. 12 1996 106 109
3. N. Barzilai, and I. Gabriely The role of fat depletion in the biological benefits of caloric restriction J. Nutr. 131 2001 903S 906S
4. N. Barzilai, S. Banerjee, M. Hawkins, W. Chen, and L. Rossetti Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat J. Clin. Invest. 101 1998 1353 1361
5. M. Blüher, M.D. Michael, O.D. Peroni, K. Ueki, N. Carter, B.B. Kahn, and C.R. Kahn Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance Dev. Cell 3 2002 25 38
6. M. Blüher, B.B. Kahn, and C.R. Kahn Extended longevity in mice lacking the insulin receptor in adipose tissue Science 299 2003 572 574
7. M. Bonafe, M. Barbieri, F. Marchegiani, F. Olivieri, E. Ragno, C. Giampieri, E. Mugianesi, M. Centurelli, C. Franceschi, and G. Paolisso Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control J. Clin. Endocrinol. Metab. 88 2003 3299 3304
8. D.J. Clancy, D. Gems, L.G. Harshman, S. Oldham, H. Stocker, E. Hafen, S.J. Leevers, and L. Partridge Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein Science 292 2001 104 106
9. M. Das, I. Gabriely, and N. Barzilai Caloric restriction, body fat and ageing in experimental models Obes. Rev. 5 2004 13 19
10. P. Fabrizio, F. Pozza, S.D. Pletcher, C.M. Gendron, and V.D. Longo Regulation of longevity and stress resistance by Sch9 in yeast Science 292 2001 288 290
11. K. Flurkey, J. Papaconstantinou, R.A. Miller, and D.E. Harrison Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production Proc. Natl Acad. Sci. USA 98 2001 6736 6741
12. J.F. Fries Aging, natural death, and the compression of morbidity N. Engl. J. Med. 303 1980 130 135
13. M.E. Giannakou, M. Goss, M.A. Junger, E. Hafen, S.J. Leevers, and L. Partridge Long-lived Drosophila with overexpressed dFOXO in adult fat body Science 305 2004 361
14. D.E. Harrison, J.R. Archer, and C.M. Astle Effects of food restriction on aging: separation of food intake and adiposity Proc. Natl Acad. Sci. USA 81 1984 1835 1838
15. M. Holzenberger, J. Dupont, B. Ducos, P. Leneuve, A. Geloen, P.C. Even, P. Cervera, and Y. Le Bouc IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice Nature 421 2003 182 187
16. M. Holzenberger, L. Kappeler, and C. De Magalhaes Filho IGF-1 signaling and aging Exp. Gerontol. 39 2004 1761 1764
17. M. Katic, and C.R. Kahn The role of insulin and IGF-1 signaling in longevity Cell Mol. Life Sci. 62 2005 320 343
18. E.B. Katz, A.E. Stenbit, K. Hatton, R. DePinho, and M.J. Charron Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4 Nature 377 1995 151 155
19. C. Kenyon, J. Chang, E. Gensch, A. Rudner, and R. Tabtiang A C. elegans mutant that lives twice as long as wild type Nature 366 1993 461 464
20. K.D. Kimura, H.A. Tissenbaum, Y. Liu, and G. Ruvkun daf-2, an insulin receptor-like gene that regulates longevity and diapause in caenorhabditis elegans Science 277 1997 942 946
21. J. Koubova, and L. Guarente How does calorie restriction work? Genes Dev. 17 2003 313 321
22. J.P. Liu, J. Baker, A.S. Perkins, E.J. Robertson, and A. Efstratiadis Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r) Cell 75 1993 59 72
23. J. Moitra, M.M. Mason, M. Olive, D. Krylov, O. Gavrilova, B. Marcus-Samuels, L. Feigenbaum, E. Lee, T. Aoyama, M. Eckhaus, M.L. Reitman, and C. Vinson Life without fat: a transgenic mouse Genes Dev. 12 1998 3168 3181
24. S. Mora, and J.E. Pessin An adipocentric view of signaling and intracellular trafficking Diabetes Metab. Res. Rev. 18 2002 345 356
25. G. Paolisso, S. Ammendola, A. Del Buono, A. Gambardella, M. Riondino, M.R. Tagliamonte, M.R. Rizzo, C. Carella, and M. Varricchio Serum levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 in healthy centenarians: relationship with plasma leptin and lipid concentrations, insulin action, and cognitive function J. Clin. Endocrinol. Metab. 82 1997 2204 2209
26. G. Paolisso, M. Barbieri, M. Bonafe, and C. Franceschi Metabolic age modelling: the lesson from centenarians Eur. J. Clin. Invest. 30 2000 888 894
27. F. Picard, and L. Guarente Molecular links between aging and adipose tissue Int. J. Obes. Relat. Metab. Disord. 29 2005 S36 S39
28. F. Picard, M. Kurtev, N. Chung, A. Topark-Ngarm, T. Senawong, R. Machado De Oliveira, M. Leid, M.W. McBurney, and L. Guarente Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma Nature 429 2004 771 776
29. G.M. Reaven Banting lecture 1988. Role of insulin resistance in human disease Diabetes 37 1988 1595 1607
30. J.T. Rodgers, C. Lerin, W. Haas, S.P. Gygi, B.M. Spiegelman, and P. Puigserver Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1 Nature 434 2005 113 118
31. S.R. Ross, R.A. Graves, and B.M. Spiegelman Targeted expression of a toxin gene to adipose tissue: transgenic mice resistant to obesity Genes Dev. 7 1993 1318 1324
32. I. Shimomura, R.E. Hammer, J.A. Richardson, S. Ikemoto, Y. Bashmakov, J.L. Goldstein, and M.S. Brown Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy Genes Dev. 12 1998 3182 3194
33. I. Shimokawa, Y. Higami, T. Tsuchiya, H. Otani, T. Komatsu, T. Chiba, and H. Yamaza Life span extension by reduction of the growth hormone-insulin-like growth factor-1 axis: relation to caloric restriction FASEB J. 17 2003 1108 1109
34. W.E. Sonntag, C.S. Carter, Y. Ikeno, K. Ekenstedt, C.S. Carlson, R.F. Loeser, S. Chakrabarty, S. Lee, C. Bennett, R. Ingram, T. Moore, and M. Ramsey Adult-onset growth hormone and insulin-like growth factor I deficiency reduces neoplastic disease, modifies age-related pathology, and increases life span Endocrinology 146 2005 2920 2932
35. R.W. Steger, A. Bartke, and M. Cecim Premature ageing in transgenic mice expressing different growth hormone genes J. Reprod. Fertil. 46 1993 61 75
36. M. Tatar, A. Kopelman, D. Epstein, M.P. Tu, C.M. Yin, and R.S. Garofalo A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function Science 292 2001 107 110
37. R. Weindruch, and R.L. Walford The Retardation of Aging and Diseases by Dietary Restriction 1998 Thomas, C.C. Springfield, IL