Metabolic consequences of pregnancy-associated plasma protein-A deficiency in mice: Exploring possible relationship to the longevity phenotype

Journal of Endocrinology

Volumn 198, Issue 3, 2008, Pages 599-605

  Conover, Cheryl A ^a   Mason, Megan A ^a   Levine, James A ^a   Novak, Colleen M ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; PREGNANCY ASSOCIATED PLASMA PROTEIN A;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CALORIMETRY; CONTROLLED STUDY; EMBRYO; ENERGY EXPENDITURE; FEMALE; FOOD INTAKE; GENE DELETION; HOMEOSTASIS; INSULIN RESISTANCE; INSULIN SENSITIVITY; KNOCKOUT MOUSE; LONGEVITY; MALE; METABOLIC DISORDER; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET; PHENOTYPE; PHYSICAL ACTIVITY; PRIORITY JOURNAL; WILD TYPE;

ANALYSIS OF VARIANCE; ANIMALS; EATING; ENERGY METABOLISM; FEMALE; GLUCOSE TOLERANCE TEST; IMMUNOHISTOCHEMISTRY; LONGEVITY; MALE; MICE; MICE, KNOCKOUT; PANCREAS; PREGNANCY-ASSOCIATED PLASMA PROTEIN-A;

EID: 53349143823     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1677/JOE-08-0179     Document Type: Article

References (39)

1. Apfeld J, O'Connor G, McDonagh T, DiStefano PS & Curtis R 2004 The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans. Genes and Development 18 3004-3009.
2. Arch JRS, Hislop D, Wang SJY & Speakman JR 2006 Some mathematical and technical issues in the measurement and interpretation of open-circuit indirect calorimetry in small animals. International Journal of Obesity 30 1322-1331.
3. Balaban RS, Nemoto S & Finkel T 2005 Mitochondria, oxidants, and aging. Cell 120 483-495.
4. Bale LK & Conover CA 2005 Disruption of insulin-like growth factor-II imprinting during embryonic development rescues the dwarf phenotype of mice null for pregnancy-associated plasma protein-A. Journal of Endocrinology 186 325-331.
5. Barbieri M, Bonafe M, Franceschi C & Paolisso G 2003a Insulin/ IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans. American Journal of Physiology. Endocrinology and Metabolism 285 E1064-E1071.
6. Barbosa MT, Soares SM, Novak CM, Sinclair D, Levine JA, Aksoy P & Chini EN 2007 The enzyme CD38 (a NAD glycohydrolase, EC 3.2.2.5) is necessary for the development of diet-induced obesity. FASEB Journal 21 3629-3639.
7. Bartke A, Brown-Borg H, Mattison J, Kinney B, Hauck S & Wright C 2001 Prolonged longevity of hypopituitary dwarf mice. Experimental Gerontology 36 21-28.
8. Bluher M, Kahn BB & Kahn CR 2003 Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 299 572-574.
9. Boldt HB & Conover CA 2007 Pregnancy-associated plasma protein-A (PAPP-A): a local regulator of IGF bioavailabihty through cleavage of IGFBPs. Growth Hormone and IGF Research 17 10-18.
10. Bonkowski MS, Rocha JS, Masternak MM, Al Regaiey KA & Bartke A 2006 Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction. PNAS 103 7901-7905.
11. Broughton SJ, Piper MDW, Ikeya T, Bass TM, Jacobson J, Driege Y, Martinez P, Hafen E, Withers DJ, Leevers SJ et al. 2005 Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands. PNAS 102 3105-3110.
12. Conover CA & Bale LK 2007 Loss of pregnancy-associated plasma protein A extends lifespan in mice. Aging Cell 6 727-729.
13. Conover CA, Bale LK, Overgaard MT, Johnstone EW, Laursen UH, Fuchtbauer E-M, Oxvig C & van Deursen J 2003 Metalloproteinase pregnancy-associated plasma protein A is a critical growth regulatory factor during fetal development. Development 131 1187-1194.
14. Coschigano KT, Holland AN, Riders ME, List EO, Flyvbjerg A & Kopchick JJ 2003 Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span. Endocrinology 144 3799-3810.
15. Devedjian JC, George M, Casellas A, Pujol A, Visa J, Pelegrin M, Gros L & Bosch F 2000 Transgenic mice overexpressing insulin-like growth factor II in β cells develop type 2 diabetes. Journal of Clinical Investigation 105 731-740.
16. Dominici FP, Hauck S, Argentino DP, Bartke A & Turyn D 2002 Increased insulin sensitivity and upregulation of insulin receptor, insulin receptor substrate (IRS)-1 and IRS-2 in liver of Ames dwarf mice. Journal of Endocrinology 173 81-94.
17. Facchini FS, Hua N, Abbasi F & Reaven GM 2001 Insulin resistance as a predictor of age-related diseases. Journal of Clinical Endocrinology and Metabolism 86 3574-3578.
18. Faulks SC, Turner N, Else PL & Hulbert AJ 2006 Calorie restriction in mice: effects on body composition, daily activity, metabolic rate, mitochondrial reactive oxygen species production, and membrane fatty acid composition. Journal of Gerontology: Biological Sciences 61A 781-794.
19. Ferrannini E, Vichi S, Beck-Nielsen H, Laasko M, Paohsso G & Smith U 1996 For European Group for the Study of Insulin Resistance (EGIR). Insulin action and age. Diabetes 45 947-953.
20. Herndon LA, Schmeissner PJ, Dudaronek JM, Brown PA, Listner KM, Sakano Y, Paupard MC, Hall DH & Driscoll M 2002 Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans. Nature 419 808-814.
21. Holzenberger M, Dupont J, Ducos B, Leneuve P, Geloen A, Even PC, Cervera P & Le Bouc Y 2003 IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 421 182-187.
22. Holzenberger M, Kappeler L & De Magalhaes Filho C 2004 IGF-1 signaling and aging. Experimental Gerontology 39 1761-1764.
23. Hulbert AJ, Clancy DJ, Mair W, Braeckman BP, Gems D & Partridge L 2004 Metabolic rate is not reduced by dietary-restriction or by lowered insulin/IGF-1 signalling and is not correlated with individual lifespan in Drosophila melanogaster. Experimental Gerontology 39 1137-1143.
24. Kenyon C 2001 A conserved regulatory system for aging. Cell 105 165-168.
25. Krystal BS & Yu BP 1994 Aging and its modulation by dietary restriction. In Modulation of Aging Process by Dietary Restriction, pp 1-36. Ed. BP Yu. London: CRC Press.
26. Kulkarni RN, Holzenberger M, Shih DQ, Ozcan U, Stoffel M, Magnuson MA & Kahn P, 2002 β-Cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter β-cell mass. Nature Genetics 31 111-115.
27. Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, McGuinness OP, Chikuda H, Yamaguchi M, Kawaguchi H et al. 2005 Suppression of aging in mice by the hormone klotho. Science 309 1829-1833.
28. Lane MA, Baer DJ, Rumpler WV, Weindruch R, Ingram DK, Tilmont EM, Cutler RG & Roth GS 1996 Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents. PNAS 93 4159-4164.
29. Liu J-L, Coschigano KT, Robertson K, Lipsett M, Guo Y, Kopchick JJ, Kumar U & Liu YL 2004 Disruption of growth hormone receptor gene causes diminished pancreatic islet size and increased insulin sensitivity in mice. American Journal of Physiology Endocrinology and Metabolism 287 E405-E413.
30. Masoro EJ 2005 Overview of caloric restriction and ageing. Mechanisms of Ageing and Development 126 913-922.
31. Masternak MM, Al-Regaiey KA, Del Rosario Lim MM, Jimenez-Ortega V, Panici JA, Bonkowski MS & Bartke A 2005 Effects of caloric restriction on insulin pathway gene expression in the skeletal muscle and liver of normal and long-lived GHR-KO mice. Experimental Gerontology 40 679-684.
32. Novak CM, Kotz CM & Levine JA 2006 Central orexin sensitivity, physical activity, and obesity in diet-induced obese and diet-resistant rats. American Journal of Physiology. Endocrinology and Metabolism 290 E396-E403.
33. Packard GC & Boardman TJ 1999 The use of percentages and size-specific indices to normalize physiological data for variation in body size: wasted time, wasted effort? Comparative Biochemistry and Physiology, Part A 122 37-44.
34. Papaconstantinou J, DeFord JH, Gerstner A, Hsieh C-C, Boylston WH, Guigneaux MM, Flurkey K & Harrison DE 2005 Hepatic gene and protein expression of primary components of the IGF-I axis in long lived Snell dwarf mice. Mechanisms of Ageing and Development 126 692-704.
35. Parsons JA, Bartke A & Sorenson RL 1995 Number and size of islets of Langerhans in pregnant, human growth hormone-expressing transgenic, and pituitary dwarf trace: effect of lactogenic hormones. Endocrinology 136 2013-2021.
36. Richardson A, Liu F, Adamo ML, Van Remmen H & Nelson JF 2004 The role of insulin and insulin-like growth factor-I in mammalian ageing. Best Practice and Research. Clinical Endocrinology and Metabolism 18 393-406.
37. Rincon M, Muzumdar R, Atzmon G & Barzilai N 2004 The paradox of the insulin/IGF-1 signaling pathway in longevity. Mechanisms of Ageing and Development 125 397-403.
38. Tang Z, Yu R, Lu Y, Parlow AF & Liu J-L 2005 Age-dependerit onset of liver-specific IGF-I gene deficiency and its persistence in old age: implications for postnatal growth and insulin resistance in LID mice. American Journal of Physiology. Endocrinology and Metabolism 289 E288-E295.
39. Yakar S, Liu J-L, Fernandez AM, Wu Y, Schally AV, Frystyk J, Chernausek SD, Mejia W & Le Roith D 2001 Liver-specific igf-1 gene deletion leads to muscle insulin insensitivity. Diabetes 50 1110-1118.