AID targeting: Old mysteries and new challenges

Trends in Immunology

Volumn 36, Issue 9, 2015, Pages 527-535

  Chandra, Vivek ^a   Bortnick, Alexandra ^a   Murre, Cornelis ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

AID; CSR; Immunoglobulin loci; SHM

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; ANTIBODY; DNA; E PROTEIN; IMMUNOGLOBULIN; RNA POLYMERASE; TRANS ACTING FACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); CYTIDINE DEAMINASE; PROTEIN BINDING;

ADAPTIVE IMMUNITY; ANTIBODY RESPONSE; B CELL LYMPHOMA; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CLINICAL RESEARCH; CONCEPTUAL FRAMEWORK; DEAMINATION; DNA METHYLATION; EXON; EXOSOME; GENE EXPRESSION; GENE FREQUENCY; GENE LOCUS; GENE MUTATION; GENE TARGETING; HUMAN; IMMUNE SYSTEM; NONHUMAN; PROTEIN PHOSPHORYLATION; PROTEIN SECONDARY STRUCTURE; REVIEW; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION TERMINATION; ANIMAL; ANTIBODY PRODUCTION; CHEMISTRY; GENE EXPRESSION REGULATION; GENE REARRANGEMENT; GENETICS; IMMUNOLOGY; METABOLISM; PROTEIN DOMAIN;

ANIMALS; ANTIBODY FORMATION; CYTIDINE DEAMINASE; GENE EXPRESSION REGULATION; GENETIC LOCI; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULINS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; TRANSCRIPTION FACTORS;

EID: 84940585917     PISSN: 14714906     EISSN: 14714981     Source Type: Journal    
DOI: 10.1016/j.it.2015.07.003     Document Type: Review

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