Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability

Cell

Volumn 159, Issue 7, 2014, Pages 1538-1548

  Meng, Fei Long ^a   Du, Zhou ^a,b   Federation, Alexander ^c   Hu, Jiazhi ^a   Wang, Qiao ^d   Kieffer Kwon, Kyong Rim ^e   Meyers, Robin M ^a   Amor, Corina ^a   Wasserman, Caitlyn R ^a   Neuberg, Donna ^f   Casellas, Rafael ^e   Nussenzweig, Michel C ^d   Bradner, James E ^c   Liu, X Shirley ^f   Alt, Frederick W ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b TONGJI UNIVERSITY   (China)

^c HARVARD MEDICAL SCHOOL   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

^e NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^f HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); CYTIDINE DEAMINASE;

ANIMAL CELL; ARTICLE; B CELL LYMPHOMA; CELL LINEAGE; CELLS BY BODY ANATOMY; GENE TARGETING; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENOMIC INSTABILITY; GERMINAL CENTER; HUMAN; HUMAN CELL; MOUSE; NEOPLASM; NONHUMAN; NUCLEOTIDE SEQUENCE; OVERLAPPING GENE; ANIMAL; B LYMPHOCYTE; ENHANCER REGION; GENE REARRANGEMENT; METABOLISM; TRANSCRIPTION INITIATION SITE;

ANIMALS; B-LYMPHOCYTES; CYTIDINE DEAMINASE; ENHANCER ELEMENTS, GENETIC; GENOMIC INSTABILITY; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; MICE; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC;

EID: 84919903836     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2014.11.014     Document Type: Article

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