NKX2-5 mutations causative for congenital heart disease retain functionality and are directed to hundreds of targets

eLife

Volumn 4, Issue JULY2015, 2015, Pages

  Bouveret, Romaric ^a,b   Waardenberg, Ashley J ^a,c   Schonrock, Nicole ^a,b   Ramialison, Mirana ^a,b,d   Doan, Tram ^a   de jong, Danielle ^a   Bondue, Antoine ^e,f   Kaur, Gurpreet ^d   Mohamed, Stephanie ^a   Fonoudi, Hananeh ^a,b,g   Chen, Chiann Mun ^h   Wouters, Merridee A ^i,j   Bhattacharya, Shoumo ^h   Plachta, Nicolas ^d   Dunwoodie, Sally L ^a,b   Chapman, Gavin ^a,b   Blanpain, Cédric ^e   Harvey, Richard P ^a,b  

^a VICTOR CHANG CARDIAC RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c Children s Medical Research Institute   (Australia)

^d EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^e UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^f ERASME HOSPITAL   (Belgium)

^g ROYAN INSTITUTE FOR REPRODUCTIVE BIOMEDICINE   (Iran)

^h UNIVERSITY OF OXFORD   (United Kingdom)

ⁱ OLIVIA NEWTON JOHN CANCER RESEARCH INSTITUTE   (Australia)

^j DEAKIN UNIVERSITY   (Australia)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA ADENINE METHYLTRANSFERASE; ETS PROTEIN; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 68; HOX PROTEIN; NUCLEAR FACTOR I; PONASTERONE A; SERUM RESPONSE FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ELK 1; TRANSCRIPTION FACTOR ELK 4; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NKX2.5; TRANSCRIPTION FACTOR TBX5; UNCLASSIFIED DRUG; HOMEOBOX PROTEIN NKX-2.5; HOMEODOMAIN PROTEIN; MUTANT PROTEIN; NKX2-5 PROTEIN, MOUSE; PROTEIN BINDING;

ARTICLE; CARBOHYDRATE METABOLISM; CONGENITAL HEART DISEASE; CYTOMEGALOVIRUS; ENDOTHELIUM CELL; GENE EXPRESSION; GENE MUTATION; HEART DEVELOPMENT; HEART MUSCLE CELL; IMMUNOFLUORESCENCE; MUSCLE CONTRACTION; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN AGGREGATION; ANIMAL; GENE REGULATORY NETWORK; GENETICS; HEART DISEASES; METABOLISM; MOUSE; MUTATION; REGULON;

ANIMALS; GENE REGULATORY NETWORKS; HEART DISEASES; HOMEOBOX PROTEIN NKX-2.5; HOMEODOMAIN PROTEINS; MICE; MUTANT PROTEINS; MUTATION; PROTEIN BINDING; REGULON; TRANSCRIPTION FACTORS;

EID: 84940567692     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.06942     Document Type: Article

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