Tim-3 promotes intestinal homeostasis in DSS colitis by inhibiting M1 polarization of macrophages

Clinical Immunology

Volumn 160, Issue 2, 2015, Pages 328-335

  Jiang, Xingwei ^a,b,f   Yu, Jiahui ^c   Shi, Qingzhu ^a   Xiao, Yan ^d   Wang, Wei ^a,c   Chen, Guojiang ^a   Zhao, Zhi ^e   Wang, Renxi ^a   Xiao, He ^a   Hou, Chunmei ^a   Feng, Jiannan ^a   Ma, Yuanfang ^c   Shen, Beifen ^a   Wang, Lili ^b   Li, Yan ^a   Han, Gencheng ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b State Key Laboratory of Toxicology and Medical Countermeasures   (China)

^c HENAN UNIVERSITY   (China)

^d CHINESE PLA GENERAL HOSPITAL   (China)

^e ZHENGZHOU PEOPLE S HOSPITAL   (China)

^f BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

DSS colitis; Immune homeostasis; Macrophages; Tim 3

Indexed keywords

ARGININE; DOCUSATE SODIUM; IMMUNOGLOBULIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; MUCIN 3; PROTEIN; T CELL IMMUNOGLOBULIN MUCIN 3 PROTEIN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; DEXTRAN SULFATE; HAVCR2 PROTEIN, MOUSE; IRF3 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE; VIRUS RECEPTOR;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FUNCTION; COLITIS; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; HOMEOSTASIS; IMMUNOCOMPETENT CELL; INNATE IMMUNITY; INTESTINAL HOMEOSTASIS; INTESTINE FUNCTION; LAMINA PROPRIA; MACROPHAGE FUNCTION; MACROPHAGE POLARIZATION; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PHENOTYPE; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; T LYMPHOCYTE; ANIMAL; CHEMICALLY INDUCED; COCULTURE; COLON; DISEASE MODEL; GENE SILENCING; GENETICS; IMMUNOLOGY; INFLAMMATORY BOWEL DISEASE; KNOCKOUT MOUSE; LYMPHOCYTE; MACROPHAGE; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ADOPTIVE TRANSFER; ANIMALS; COCULTURE TECHNIQUES; COLITIS; COLON; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; GENE KNOCKDOWN TECHNIQUES; HOMEOSTASIS; INFLAMMATORY BOWEL DISEASES; INTERFERON REGULATORY FACTOR-3; LYMPHOCYTES; MACROPHAGES; MICE; MICE, KNOCKOUT; PHOSPHORYLATION; RECEPTORS, VIRUS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84940395851     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2015.07.008     Document Type: Article

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