-
1
-
-
48749089688
-
New roles for TIM family members in immune regulation
-
Kuchroo V.K., Dardalhon V., Xiao S., Anderson A.C. New roles for TIM family members in immune regulation. Nat. Rev. Immunol. 2008, 8:577-580.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 577-580
-
-
Kuchroo, V.K.1
Dardalhon, V.2
Xiao, S.3
Anderson, A.C.4
-
2
-
-
34247895422
-
Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17
-
Nakae S., Iwakura Y., Suto H., et al. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J. Leukoc. Biol. 2007, 81:1258-1268.
-
(2007)
J. Leukoc. Biol.
, vol.81
, pp. 1258-1268
-
-
Nakae, S.1
Iwakura, Y.2
Suto, H.3
-
3
-
-
40849120400
-
Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis
-
Seki M., Oomizu S., Sakata K.M., et al. Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis. Clin. Immunol. 2008, 127:78-88.
-
(2008)
Clin. Immunol.
, vol.127
, pp. 78-88
-
-
Seki, M.1
Oomizu, S.2
Sakata, K.M.3
-
4
-
-
0242708767
-
Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance
-
Sanchez-Fueyo A., Tian J., Picarella D., et al. Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance. Nat. Immunol. 2003, 4:1093-1101.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1093-1101
-
-
Sanchez-Fueyo, A.1
Tian, J.2
Picarella, D.3
-
5
-
-
33745035874
-
Dysregulated T cell expression of TIM3 in multiple sclerosis
-
Koguchi K., Anderson D.E., Yang L., O'Connor K.C., Kuchroo V.K., Hafler D.A. Dysregulated T cell expression of TIM3 in multiple sclerosis. J. Exp. Med. 2006, 203:1413-1418.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1413-1418
-
-
Koguchi, K.1
Anderson, D.E.2
Yang, L.3
O'Connor, K.C.4
Kuchroo, V.K.5
Hafler, D.A.6
-
6
-
-
84864353767
-
The impaired immune regulation of autoimmune hepatitis is linked to a defective galectin-9/tim-3 pathway
-
Liberal R., Grant C.R., Holder B.S., Ma Y., Mieli-Vergani G., Vergani D., Longhi M.S. The impaired immune regulation of autoimmune hepatitis is linked to a defective galectin-9/tim-3 pathway. Hepatology 2012 Aug, 56(2):677-686.
-
(2012)
Hepatology
, vol.56
, Issue.2
, pp. 677-686
-
-
Liberal, R.1
Grant, C.R.2
Holder, B.S.3
Ma, Y.4
Mieli-Vergani, G.5
Vergani, D.6
Longhi, M.S.7
-
7
-
-
84863777517
-
+ T cells in rheumatoid arthritis
-
+ T cells in rheumatoid arthritis. Inflammation 2012, 35:633-637.
-
(2012)
Inflammation
, vol.35
, pp. 633-637
-
-
Lee, J.1
Park, E.J.2
Noh, J.W.3
Hwang, J.W.4
Bae, E.K.5
Ahn, J.K.6
Koh, E.M.7
Cha, H.S.8
-
8
-
-
79961160736
-
+ T cells evade Treg cell suppression
-
Jul 17
-
+ T cells evade Treg cell suppression. Nat. Med. Jul 17 2011, 17(8):989-995.
-
(2011)
Nat. Med.
, vol.17
, Issue.8
, pp. 989-995
-
-
Elahi, S.1
Dinges, W.L.2
Lejarcegui, N.3
Laing, K.J.4
Collier, A.C.5
Koelle, D.M.6
McElrath, M.J.7
Horton, H.8
-
9
-
-
84867144615
-
Tim-3/galectin-9 signaling pathway mediates T cell dysfunction and predicts poor prognosis in patients with HBV-associated hepatocellular carcinoma
-
Apr 13
-
Li H., Wu K., Tao K., Chen L., Zheng Q., Lu X., Liu J., Shi L., Liu C., Wang G., Zou W. Tim-3/galectin-9 signaling pathway mediates T cell dysfunction and predicts poor prognosis in patients with HBV-associated hepatocellular carcinoma. Hepatology Apr 13 2012, 10.1002/hep.25777.
-
(2012)
Hepatology
-
-
Li, H.1
Wu, K.2
Tao, K.3
Chen, L.4
Zheng, Q.5
Lu, X.6
Liu, J.7
Shi, L.8
Liu, C.9
Wang, G.10
Zou, W.11
-
11
-
-
15544382565
-
Immunity, inflammation, and allergy in the gut
-
Macdonald T.T., Monteleone G. Immunity, inflammation, and allergy in the gut. Science 2005, 307:1920-1925.
-
(2005)
Science
, vol.307
, pp. 1920-1925
-
-
Macdonald, T.T.1
Monteleone, G.2
-
12
-
-
79959271087
-
Intestinal homeostasis and its breakdown in inflammatory bowel disease
-
Maloy K.J., Powrie F. Intestinal homeostasis and its breakdown in inflammatory bowel disease. Nature 2011, 474:298-306.
-
(2011)
Nature
, vol.474
, pp. 298-306
-
-
Maloy, K.J.1
Powrie, F.2
-
13
-
-
70949107842
-
Inflammatory bowel disease
-
Abraham C., Cho J.H. Inflammatory bowel disease. N. Engl. J. Med. 2009, 361:2066-2078.
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 2066-2078
-
-
Abraham, C.1
Cho, J.H.2
-
14
-
-
0030209985
-
+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5
-
+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J. Immunol. 1996, 157:1261-1270.
-
(1996)
J. Immunol.
, vol.157
, pp. 1261-1270
-
-
Fuss, I.J.1
Neurath, M.2
Boirivant, M.3
-
15
-
-
0030995575
-
Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells
-
Monteleone G., Biancone L., Marasco R., et al. Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells. Gastroenterology 1997, 112:1169-1178.
-
(1997)
Gastroenterology
, vol.112
, pp. 1169-1178
-
-
Monteleone, G.1
Biancone, L.2
Marasco, R.3
-
16
-
-
0034671633
-
Up-regulation of the IL-12 receptor beta 2 chain in Crohn's disease
-
Parrello T., Monteleone G., Cucchiara S., et al. Up-regulation of the IL-12 receptor beta 2 chain in Crohn's disease. J. Immunol. 2000, 165:7234-7239.
-
(2000)
J. Immunol.
, vol.165
, pp. 7234-7239
-
-
Parrello, T.1
Monteleone, G.2
Cucchiara, S.3
-
17
-
-
0037029649
-
The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease
-
Neurath M.F., Weigmann B., Finotto S., et al. The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease. J. Exp. Med. 2002, 195:1129-1143.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1129-1143
-
-
Neurath, M.F.1
Weigmann, B.2
Finotto, S.3
-
18
-
-
67449147595
-
Interleukin-23/Th17 pathways and inflammatory bowel disease
-
Abraham C., Cho J. Interleukin-23/Th17 pathways and inflammatory bowel disease. Inflamm. Bowel Dis. 2009, 15:1090-1100.
-
(2009)
Inflamm. Bowel Dis.
, vol.15
, pp. 1090-1100
-
-
Abraham, C.1
Cho, J.2
-
19
-
-
74049161287
-
Potential role of Th17 cells in the pathogenesis of inflammatory bowel disease
-
Liu Z.J., Yadav P.K., Su J.L., Wang J.S., Fei K. Potential role of Th17 cells in the pathogenesis of inflammatory bowel disease. World J. Gastroenterol. 2009, 15:5784-5788.
-
(2009)
World J. Gastroenterol.
, vol.15
, pp. 5784-5788
-
-
Liu, Z.J.1
Yadav, P.K.2
Su, J.L.3
Wang, J.S.4
Fei, K.5
-
20
-
-
81055150391
-
Th17-related cytokines: new players in the control of chronic intestinal inflammation
-
Monteleone I., Pallone F., Monteleone G. Th17-related cytokines: new players in the control of chronic intestinal inflammation. BMC Med. 2011, 15:122.
-
(2011)
BMC Med.
, vol.15
, pp. 122
-
-
Monteleone, I.1
Pallone, F.2
Monteleone, G.3
-
21
-
-
84856603151
-
Th17 cells: interactions with predisposing factors in the immunopathogenesis of inflammatory bowel disease
-
Raza A., Yousaf W., Giannella R., Shata M.T. Th17 cells: interactions with predisposing factors in the immunopathogenesis of inflammatory bowel disease. Expert Rev. Clin. Immunol. 2012, 8:161-168.
-
(2012)
Expert Rev. Clin. Immunol.
, vol.8
, pp. 161-168
-
-
Raza, A.1
Yousaf, W.2
Giannella, R.3
Shata, M.T.4
-
22
-
-
34347262689
-
Chemically induced mouse models of intestinal inflammation
-
Wirtz S., Neufert C., Weigmann B., et al. Chemically induced mouse models of intestinal inflammation. Nat. Protoc. 2007, 2:541-546.
-
(2007)
Nat. Protoc.
, vol.2
, pp. 541-546
-
-
Wirtz, S.1
Neufert, C.2
Weigmann, B.3
-
23
-
-
84863036480
-
Investigating intestinal inflammation in DSS-induced model of IBD
-
pii: 3678
-
Kim J.J., Shajib M.S., Manocha M.M., Khan W.I. Investigating intestinal inflammation in DSS-induced model of IBD. J. Vis. Exp. 2012, 1. pii: 3678. 10.3791/3678.
-
(2012)
J. Vis. Exp.
, vol.1
-
-
Kim, J.J.1
Shajib, M.S.2
Manocha, M.M.3
Khan, W.I.4
-
24
-
-
78650602530
-
The N- and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity
-
Li Y.R., Feng J.N., Geng S.X., Han G.C., et al. The N- and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity. Mol. Immunol. 2011, 48:670-677.
-
(2011)
Mol. Immunol.
, vol.48
, pp. 670-677
-
-
Li, Y.R.1
Feng, J.N.2
Geng, S.X.3
Han, G.C.4
-
25
-
-
70350552096
-
Galectin-9 significantly prolongs the survival of fully mismatched cardiac allografts in mice
-
He Wentao, Fang Zemin, Wang Feng, et al. Galectin-9 significantly prolongs the survival of fully mismatched cardiac allografts in mice. Transplantation 2009, 88:782-790.
-
(2009)
Transplantation
, vol.88
, pp. 782-790
-
-
He, W.1
Fang, Z.2
Wang, F.3
-
26
-
-
15944422109
-
The peroxisome proliferator-activated receptor γ ligand rosiglitazone delays the onset of inflammatory bowel disease in mice with interleukin 10 deficiency
-
Lytle C., Tod T.J., Vo K.T., Lee J.W., Atkinson R.W., Straus D.S. The peroxisome proliferator-activated receptor γ ligand rosiglitazone delays the onset of inflammatory bowel disease in mice with interleukin 10 deficiency. Inflamm. Bowel Dis. 2005, 11:231-243.
-
(2005)
Inflamm. Bowel Dis.
, vol.11
, pp. 231-243
-
-
Lytle, C.1
Tod, T.J.2
Vo, K.T.3
Lee, J.W.4
Atkinson, R.W.5
Straus, D.S.6
-
27
-
-
79952478107
-
Microbial ecology of the murine gut associated with the development of dextran sodium sulfate-induced colitis
-
Nagalingam N.A., Kao J.Y., Young V.B. Microbial ecology of the murine gut associated with the development of dextran sodium sulfate-induced colitis. Inflamm. Bowel Dis. 2011, 17(4):917-926.
-
(2011)
Inflamm. Bowel Dis.
, vol.17
, Issue.4
, pp. 917-926
-
-
Nagalingam, N.A.1
Kao, J.Y.2
Young, V.B.3
-
28
-
-
34248572345
-
TH-17 cells in the circle of immunity and autoimmunity
-
Bettelli E., Oukka M., Kuchroo V.K. TH-17 cells in the circle of immunity and autoimmunity. Nat. Immunol. 2007, 8:345-350.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 345-350
-
-
Bettelli, E.1
Oukka, M.2
Kuchroo, V.K.3
-
29
-
-
41149083753
-
Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha
-
Liu L.Y., Bates M.E., Jarjour N.N., Busse W.W., Bertics P.J., Kelly E.A. Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha. J. Immunol. 2007, 179(7):4840-4848.
-
(2007)
J. Immunol.
, vol.179
, Issue.7
, pp. 4840-4848
-
-
Liu, L.Y.1
Bates, M.E.2
Jarjour, N.N.3
Busse, W.W.4
Bertics, P.J.5
Kelly, E.A.6
-
30
-
-
33645766472
-
STAT1 in peripheral tissue differentially regulates homing of antigen-specific Th1 and Th2 cells
-
Mikhak Z., Fleming C.M., Medoff B.D., Thomas S.Y., Tager A.M., Campanella G.S., Luster A.D. STAT1 in peripheral tissue differentially regulates homing of antigen-specific Th1 and Th2 cells. J. Immunol. 2006, 176(8):4959-4967.
-
(2006)
J. Immunol.
, vol.176
, Issue.8
, pp. 4959-4967
-
-
Mikhak, Z.1
Fleming, C.M.2
Medoff, B.D.3
Thomas, S.Y.4
Tager, A.M.5
Campanella, G.S.6
Luster, A.D.7
-
31
-
-
77958572323
-
Regulation of the Ifng locus in the context of T-lineage specification and plasticity
-
Balasubramani A., Mukasa R., Hatton R.D., et al. Regulation of the Ifng locus in the context of T-lineage specification and plasticity. Immunol. Rev. 2010, 238(1):216-232.
-
(2010)
Immunol. Rev.
, vol.238
, Issue.1
, pp. 216-232
-
-
Balasubramani, A.1
Mukasa, R.2
Hatton, R.D.3
-
33
-
-
79955580889
-
Epithelial phosphatidylinositol-3-kinase signaling is required for β-catenin activation and host defense against Citrobacter rodentium infection
-
Brown J.B., Cheresh P., Goretsky T., Managlia E., Grimm G.R., Ryu H., Zadeh M., Dirisina R., Barrett T.A. Epithelial phosphatidylinositol-3-kinase signaling is required for β-catenin activation and host defense against Citrobacter rodentium infection. Infect. Immun. 2011, 79(5):1863-1872.
-
(2011)
Infect. Immun.
, vol.79
, Issue.5
, pp. 1863-1872
-
-
Brown, J.B.1
Cheresh, P.2
Goretsky, T.3
Managlia, E.4
Grimm, G.R.5
Ryu, H.6
Zadeh, M.7
Dirisina, R.8
Barrett, T.A.9
-
34
-
-
77951673268
-
TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity
-
Freeman G.J., Casasnovas J.M., Umetsu D.T., DeKruyff R.H. TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity. Immunol. Rev. 2010, 235:172-189.
-
(2010)
Immunol. Rev.
, vol.235
, pp. 172-189
-
-
Freeman, G.J.1
Casasnovas, J.M.2
Umetsu, D.T.3
DeKruyff, R.H.4
-
35
-
-
73349083370
-
Involvement of T cell Ig Mucin-3 (Tim-3) in the negative regulation of inflammatory bowel disease
-
Li X., Chen G.J., Li Y.R., Han G.C., et al. Involvement of T cell Ig Mucin-3 (Tim-3) in the negative regulation of inflammatory bowel disease. Clin. Immunol. 2010, 134:169-177.
-
(2010)
Clin. Immunol.
, vol.134
, pp. 169-177
-
-
Li, X.1
Chen, G.J.2
Li, Y.R.3
Han, G.C.4
-
36
-
-
44449135110
-
Lack of TIM-3 immunoregulation in multiple sclerosis
-
Li Y., Anderson D.E., Kuchroo J., Hafler D.A. Lack of TIM-3 immunoregulation in multiple sclerosis. J. Immunol. 2008, 180:4409-4414.
-
(2008)
J. Immunol.
, vol.180
, pp. 4409-4414
-
-
Li, Y.1
Anderson, D.E.2
Kuchroo, J.3
Hafler, D.A.4
-
38
-
-
33748754285
-
Chronic intermittent psychosocial stress (social defeat/overcrowding) in mice increases the severity of an acute DSS-induced colitis and impairs regeneration
-
Reber S.O., Obermeier F., Straub R.H., Falk W., Neumann I.D. Chronic intermittent psychosocial stress (social defeat/overcrowding) in mice increases the severity of an acute DSS-induced colitis and impairs regeneration. Endocrinology 2006, 147(10):4968-4976.
-
(2006)
Endocrinology
, vol.147
, Issue.10
, pp. 4968-4976
-
-
Reber, S.O.1
Obermeier, F.2
Straub, R.H.3
Falk, W.4
Neumann, I.D.5
-
39
-
-
17644385528
-
Molecular mimicry may contribute to pathogenesis of ulcerative colitis
-
Kovvali Gopala, Das Kiron M. Molecular mimicry may contribute to pathogenesis of ulcerative colitis. FEBS Lett. 2005, 579:2261-2266.
-
(2005)
FEBS Lett.
, vol.579
, pp. 2261-2266
-
-
Kovvali, G.1
Das, K.M.2
-
40
-
-
23244455992
-
Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution
-
Heller F., Florian P., Bojarski C., Richter J., Christ M., Hillenbrand B., Mankertz J., Gitter A.H., Burgel N., Fromm M., Zeitz M., Fuss I., Strober W., Schulzke J.D. Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution. Gastroenterology 2005, 129:550-564.
-
(2005)
Gastroenterology
, vol.129
, pp. 550-564
-
-
Heller, F.1
Florian, P.2
Bojarski, C.3
Richter, J.4
Christ, M.5
Hillenbrand, B.6
Mankertz, J.7
Gitter, A.H.8
Burgel, N.9
Fromm, M.10
Zeitz, M.11
Fuss, I.12
Strober, W.13
Schulzke, J.D.14
-
41
-
-
46049093364
-
Th17 cells and autoimmune encephalomyelitis (EAE/MS)
-
Aranami T., Yamamura T. Th17 cells and autoimmune encephalomyelitis (EAE/MS). Allergol. Int. 2008, 57:115-120.
-
(2008)
Allergol. Int.
, vol.57
, pp. 115-120
-
-
Aranami, T.1
Yamamura, T.2
-
43
-
-
70350041508
-
Th17 immunity in patients with allergic asthma
-
Zhao Y., Yang J., Gao Y.D., Guo W. Th17 immunity in patients with allergic asthma. Int. Arch. Allergy Immunol. 2010, 151:297-307.
-
(2010)
Int. Arch. Allergy Immunol.
, vol.151
, pp. 297-307
-
-
Zhao, Y.1
Yang, J.2
Gao, Y.D.3
Guo, W.4
|