메뉴 건너뛰기




Volumn 145, Issue 3, 2012, Pages 230-240

Dysregulated Tim-3 expression and its correlation with imbalanced CD4 helper T cell function in ulcerative colitis

Author keywords

Gal 9; Immune regulation; T help cells; Tim 3; Ulcerative colitis

Indexed keywords

ANTIBODY; CXCL9 CHEMOKINE; DEXTRAN SULFATE; ECALECTIN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOGLOBULIN; LIGAND; MUCIN 3;

EID: 84867900850     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2012.09.001     Document Type: Article
Times cited : (37)

References (43)
  • 2
    • 34247895422 scopus 로고    scopus 로고
    • Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17
    • Nakae S., Iwakura Y., Suto H., et al. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J. Leukoc. Biol. 2007, 81:1258-1268.
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 1258-1268
    • Nakae, S.1    Iwakura, Y.2    Suto, H.3
  • 3
    • 40849120400 scopus 로고    scopus 로고
    • Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis
    • Seki M., Oomizu S., Sakata K.M., et al. Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis. Clin. Immunol. 2008, 127:78-88.
    • (2008) Clin. Immunol. , vol.127 , pp. 78-88
    • Seki, M.1    Oomizu, S.2    Sakata, K.M.3
  • 4
    • 0242708767 scopus 로고    scopus 로고
    • Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance
    • Sanchez-Fueyo A., Tian J., Picarella D., et al. Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance. Nat. Immunol. 2003, 4:1093-1101.
    • (2003) Nat. Immunol. , vol.4 , pp. 1093-1101
    • Sanchez-Fueyo, A.1    Tian, J.2    Picarella, D.3
  • 6
    • 84864353767 scopus 로고    scopus 로고
    • The impaired immune regulation of autoimmune hepatitis is linked to a defective galectin-9/tim-3 pathway
    • Liberal R., Grant C.R., Holder B.S., Ma Y., Mieli-Vergani G., Vergani D., Longhi M.S. The impaired immune regulation of autoimmune hepatitis is linked to a defective galectin-9/tim-3 pathway. Hepatology 2012 Aug, 56(2):677-686.
    • (2012) Hepatology , vol.56 , Issue.2 , pp. 677-686
    • Liberal, R.1    Grant, C.R.2    Holder, B.S.3    Ma, Y.4    Mieli-Vergani, G.5    Vergani, D.6    Longhi, M.S.7
  • 9
    • 84867144615 scopus 로고    scopus 로고
    • Tim-3/galectin-9 signaling pathway mediates T cell dysfunction and predicts poor prognosis in patients with HBV-associated hepatocellular carcinoma
    • Apr 13
    • Li H., Wu K., Tao K., Chen L., Zheng Q., Lu X., Liu J., Shi L., Liu C., Wang G., Zou W. Tim-3/galectin-9 signaling pathway mediates T cell dysfunction and predicts poor prognosis in patients with HBV-associated hepatocellular carcinoma. Hepatology Apr 13 2012, 10.1002/hep.25777.
    • (2012) Hepatology
    • Li, H.1    Wu, K.2    Tao, K.3    Chen, L.4    Zheng, Q.5    Lu, X.6    Liu, J.7    Shi, L.8    Liu, C.9    Wang, G.10    Zou, W.11
  • 11
    • 15544382565 scopus 로고    scopus 로고
    • Immunity, inflammation, and allergy in the gut
    • Macdonald T.T., Monteleone G. Immunity, inflammation, and allergy in the gut. Science 2005, 307:1920-1925.
    • (2005) Science , vol.307 , pp. 1920-1925
    • Macdonald, T.T.1    Monteleone, G.2
  • 12
    • 79959271087 scopus 로고    scopus 로고
    • Intestinal homeostasis and its breakdown in inflammatory bowel disease
    • Maloy K.J., Powrie F. Intestinal homeostasis and its breakdown in inflammatory bowel disease. Nature 2011, 474:298-306.
    • (2011) Nature , vol.474 , pp. 298-306
    • Maloy, K.J.1    Powrie, F.2
  • 13
    • 70949107842 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • Abraham C., Cho J.H. Inflammatory bowel disease. N. Engl. J. Med. 2009, 361:2066-2078.
    • (2009) N. Engl. J. Med. , vol.361 , pp. 2066-2078
    • Abraham, C.1    Cho, J.H.2
  • 14
    • 0030209985 scopus 로고    scopus 로고
    • + lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5
    • + lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J. Immunol. 1996, 157:1261-1270.
    • (1996) J. Immunol. , vol.157 , pp. 1261-1270
    • Fuss, I.J.1    Neurath, M.2    Boirivant, M.3
  • 15
    • 0030995575 scopus 로고    scopus 로고
    • Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells
    • Monteleone G., Biancone L., Marasco R., et al. Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells. Gastroenterology 1997, 112:1169-1178.
    • (1997) Gastroenterology , vol.112 , pp. 1169-1178
    • Monteleone, G.1    Biancone, L.2    Marasco, R.3
  • 16
    • 0034671633 scopus 로고    scopus 로고
    • Up-regulation of the IL-12 receptor beta 2 chain in Crohn's disease
    • Parrello T., Monteleone G., Cucchiara S., et al. Up-regulation of the IL-12 receptor beta 2 chain in Crohn's disease. J. Immunol. 2000, 165:7234-7239.
    • (2000) J. Immunol. , vol.165 , pp. 7234-7239
    • Parrello, T.1    Monteleone, G.2    Cucchiara, S.3
  • 17
    • 0037029649 scopus 로고    scopus 로고
    • The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease
    • Neurath M.F., Weigmann B., Finotto S., et al. The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease. J. Exp. Med. 2002, 195:1129-1143.
    • (2002) J. Exp. Med. , vol.195 , pp. 1129-1143
    • Neurath, M.F.1    Weigmann, B.2    Finotto, S.3
  • 18
    • 67449147595 scopus 로고    scopus 로고
    • Interleukin-23/Th17 pathways and inflammatory bowel disease
    • Abraham C., Cho J. Interleukin-23/Th17 pathways and inflammatory bowel disease. Inflamm. Bowel Dis. 2009, 15:1090-1100.
    • (2009) Inflamm. Bowel Dis. , vol.15 , pp. 1090-1100
    • Abraham, C.1    Cho, J.2
  • 19
    • 74049161287 scopus 로고    scopus 로고
    • Potential role of Th17 cells in the pathogenesis of inflammatory bowel disease
    • Liu Z.J., Yadav P.K., Su J.L., Wang J.S., Fei K. Potential role of Th17 cells in the pathogenesis of inflammatory bowel disease. World J. Gastroenterol. 2009, 15:5784-5788.
    • (2009) World J. Gastroenterol. , vol.15 , pp. 5784-5788
    • Liu, Z.J.1    Yadav, P.K.2    Su, J.L.3    Wang, J.S.4    Fei, K.5
  • 20
    • 81055150391 scopus 로고    scopus 로고
    • Th17-related cytokines: new players in the control of chronic intestinal inflammation
    • Monteleone I., Pallone F., Monteleone G. Th17-related cytokines: new players in the control of chronic intestinal inflammation. BMC Med. 2011, 15:122.
    • (2011) BMC Med. , vol.15 , pp. 122
    • Monteleone, I.1    Pallone, F.2    Monteleone, G.3
  • 21
    • 84856603151 scopus 로고    scopus 로고
    • Th17 cells: interactions with predisposing factors in the immunopathogenesis of inflammatory bowel disease
    • Raza A., Yousaf W., Giannella R., Shata M.T. Th17 cells: interactions with predisposing factors in the immunopathogenesis of inflammatory bowel disease. Expert Rev. Clin. Immunol. 2012, 8:161-168.
    • (2012) Expert Rev. Clin. Immunol. , vol.8 , pp. 161-168
    • Raza, A.1    Yousaf, W.2    Giannella, R.3    Shata, M.T.4
  • 22
    • 34347262689 scopus 로고    scopus 로고
    • Chemically induced mouse models of intestinal inflammation
    • Wirtz S., Neufert C., Weigmann B., et al. Chemically induced mouse models of intestinal inflammation. Nat. Protoc. 2007, 2:541-546.
    • (2007) Nat. Protoc. , vol.2 , pp. 541-546
    • Wirtz, S.1    Neufert, C.2    Weigmann, B.3
  • 23
    • 84863036480 scopus 로고    scopus 로고
    • Investigating intestinal inflammation in DSS-induced model of IBD
    • pii: 3678
    • Kim J.J., Shajib M.S., Manocha M.M., Khan W.I. Investigating intestinal inflammation in DSS-induced model of IBD. J. Vis. Exp. 2012, 1. pii: 3678. 10.3791/3678.
    • (2012) J. Vis. Exp. , vol.1
    • Kim, J.J.1    Shajib, M.S.2    Manocha, M.M.3    Khan, W.I.4
  • 24
    • 78650602530 scopus 로고    scopus 로고
    • The N- and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity
    • Li Y.R., Feng J.N., Geng S.X., Han G.C., et al. The N- and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity. Mol. Immunol. 2011, 48:670-677.
    • (2011) Mol. Immunol. , vol.48 , pp. 670-677
    • Li, Y.R.1    Feng, J.N.2    Geng, S.X.3    Han, G.C.4
  • 25
    • 70350552096 scopus 로고    scopus 로고
    • Galectin-9 significantly prolongs the survival of fully mismatched cardiac allografts in mice
    • He Wentao, Fang Zemin, Wang Feng, et al. Galectin-9 significantly prolongs the survival of fully mismatched cardiac allografts in mice. Transplantation 2009, 88:782-790.
    • (2009) Transplantation , vol.88 , pp. 782-790
    • He, W.1    Fang, Z.2    Wang, F.3
  • 26
    • 15944422109 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor γ ligand rosiglitazone delays the onset of inflammatory bowel disease in mice with interleukin 10 deficiency
    • Lytle C., Tod T.J., Vo K.T., Lee J.W., Atkinson R.W., Straus D.S. The peroxisome proliferator-activated receptor γ ligand rosiglitazone delays the onset of inflammatory bowel disease in mice with interleukin 10 deficiency. Inflamm. Bowel Dis. 2005, 11:231-243.
    • (2005) Inflamm. Bowel Dis. , vol.11 , pp. 231-243
    • Lytle, C.1    Tod, T.J.2    Vo, K.T.3    Lee, J.W.4    Atkinson, R.W.5    Straus, D.S.6
  • 27
    • 79952478107 scopus 로고    scopus 로고
    • Microbial ecology of the murine gut associated with the development of dextran sodium sulfate-induced colitis
    • Nagalingam N.A., Kao J.Y., Young V.B. Microbial ecology of the murine gut associated with the development of dextran sodium sulfate-induced colitis. Inflamm. Bowel Dis. 2011, 17(4):917-926.
    • (2011) Inflamm. Bowel Dis. , vol.17 , Issue.4 , pp. 917-926
    • Nagalingam, N.A.1    Kao, J.Y.2    Young, V.B.3
  • 28
    • 34248572345 scopus 로고    scopus 로고
    • TH-17 cells in the circle of immunity and autoimmunity
    • Bettelli E., Oukka M., Kuchroo V.K. TH-17 cells in the circle of immunity and autoimmunity. Nat. Immunol. 2007, 8:345-350.
    • (2007) Nat. Immunol. , vol.8 , pp. 345-350
    • Bettelli, E.1    Oukka, M.2    Kuchroo, V.K.3
  • 29
    • 41149083753 scopus 로고    scopus 로고
    • Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha
    • Liu L.Y., Bates M.E., Jarjour N.N., Busse W.W., Bertics P.J., Kelly E.A. Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha. J. Immunol. 2007, 179(7):4840-4848.
    • (2007) J. Immunol. , vol.179 , Issue.7 , pp. 4840-4848
    • Liu, L.Y.1    Bates, M.E.2    Jarjour, N.N.3    Busse, W.W.4    Bertics, P.J.5    Kelly, E.A.6
  • 30
  • 31
    • 77958572323 scopus 로고    scopus 로고
    • Regulation of the Ifng locus in the context of T-lineage specification and plasticity
    • Balasubramani A., Mukasa R., Hatton R.D., et al. Regulation of the Ifng locus in the context of T-lineage specification and plasticity. Immunol. Rev. 2010, 238(1):216-232.
    • (2010) Immunol. Rev. , vol.238 , Issue.1 , pp. 216-232
    • Balasubramani, A.1    Mukasa, R.2    Hatton, R.D.3
  • 33
    • 79955580889 scopus 로고    scopus 로고
    • Epithelial phosphatidylinositol-3-kinase signaling is required for β-catenin activation and host defense against Citrobacter rodentium infection
    • Brown J.B., Cheresh P., Goretsky T., Managlia E., Grimm G.R., Ryu H., Zadeh M., Dirisina R., Barrett T.A. Epithelial phosphatidylinositol-3-kinase signaling is required for β-catenin activation and host defense against Citrobacter rodentium infection. Infect. Immun. 2011, 79(5):1863-1872.
    • (2011) Infect. Immun. , vol.79 , Issue.5 , pp. 1863-1872
    • Brown, J.B.1    Cheresh, P.2    Goretsky, T.3    Managlia, E.4    Grimm, G.R.5    Ryu, H.6    Zadeh, M.7    Dirisina, R.8    Barrett, T.A.9
  • 34
    • 77951673268 scopus 로고    scopus 로고
    • TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity
    • Freeman G.J., Casasnovas J.M., Umetsu D.T., DeKruyff R.H. TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity. Immunol. Rev. 2010, 235:172-189.
    • (2010) Immunol. Rev. , vol.235 , pp. 172-189
    • Freeman, G.J.1    Casasnovas, J.M.2    Umetsu, D.T.3    DeKruyff, R.H.4
  • 35
    • 73349083370 scopus 로고    scopus 로고
    • Involvement of T cell Ig Mucin-3 (Tim-3) in the negative regulation of inflammatory bowel disease
    • Li X., Chen G.J., Li Y.R., Han G.C., et al. Involvement of T cell Ig Mucin-3 (Tim-3) in the negative regulation of inflammatory bowel disease. Clin. Immunol. 2010, 134:169-177.
    • (2010) Clin. Immunol. , vol.134 , pp. 169-177
    • Li, X.1    Chen, G.J.2    Li, Y.R.3    Han, G.C.4
  • 36
    • 44449135110 scopus 로고    scopus 로고
    • Lack of TIM-3 immunoregulation in multiple sclerosis
    • Li Y., Anderson D.E., Kuchroo J., Hafler D.A. Lack of TIM-3 immunoregulation in multiple sclerosis. J. Immunol. 2008, 180:4409-4414.
    • (2008) J. Immunol. , vol.180 , pp. 4409-4414
    • Li, Y.1    Anderson, D.E.2    Kuchroo, J.3    Hafler, D.A.4
  • 38
    • 33748754285 scopus 로고    scopus 로고
    • Chronic intermittent psychosocial stress (social defeat/overcrowding) in mice increases the severity of an acute DSS-induced colitis and impairs regeneration
    • Reber S.O., Obermeier F., Straub R.H., Falk W., Neumann I.D. Chronic intermittent psychosocial stress (social defeat/overcrowding) in mice increases the severity of an acute DSS-induced colitis and impairs regeneration. Endocrinology 2006, 147(10):4968-4976.
    • (2006) Endocrinology , vol.147 , Issue.10 , pp. 4968-4976
    • Reber, S.O.1    Obermeier, F.2    Straub, R.H.3    Falk, W.4    Neumann, I.D.5
  • 39
    • 17644385528 scopus 로고    scopus 로고
    • Molecular mimicry may contribute to pathogenesis of ulcerative colitis
    • Kovvali Gopala, Das Kiron M. Molecular mimicry may contribute to pathogenesis of ulcerative colitis. FEBS Lett. 2005, 579:2261-2266.
    • (2005) FEBS Lett. , vol.579 , pp. 2261-2266
    • Kovvali, G.1    Das, K.M.2
  • 41
    • 46049093364 scopus 로고    scopus 로고
    • Th17 cells and autoimmune encephalomyelitis (EAE/MS)
    • Aranami T., Yamamura T. Th17 cells and autoimmune encephalomyelitis (EAE/MS). Allergol. Int. 2008, 57:115-120.
    • (2008) Allergol. Int. , vol.57 , pp. 115-120
    • Aranami, T.1    Yamamura, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.