-
1
-
-
0024990092
-
Autoreactive T cell clones isolated from normal and autoimmune-susceptible mice exhibit lymphokine secretory and functional properties of both Th1 and Th2 cells
-
Kakkanaiah V.N., Seth A., Nagarkatti M., Nagarkatti P.S. Autoreactive T cell clones isolated from normal and autoimmune-susceptible mice exhibit lymphokine secretory and functional properties of both Th1 and Th2 cells. Clin Immunol Immunopathol 1990, 57:148-162.
-
(1990)
Clin Immunol Immunopathol
, vol.57
, pp. 148-162
-
-
Kakkanaiah, V.N.1
Seth, A.2
Nagarkatti, M.3
Nagarkatti, P.S.4
-
2
-
-
84929630106
-
Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis
-
287ra274
-
Cao Y., Goods B.A., Raddassi K., Nepom G.T., Kwok W.W., Love J.C., et al. Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis. Sci Transl Med 2015, 7:287ra274.
-
(2015)
Sci Transl Med
, vol.7
-
-
Cao, Y.1
Goods, B.A.2
Raddassi, K.3
Nepom, G.T.4
Kwok, W.W.5
Love, J.C.6
-
3
-
-
34147128572
-
Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation
-
Korn T., Reddy J., Gao W., Bettelli E., Awasthi A., Petersen T.R., et al. Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation. Nat Med 2007, 13:423-431.
-
(2007)
Nat Med
, vol.13
, pp. 423-431
-
-
Korn, T.1
Reddy, J.2
Gao, W.3
Bettelli, E.4
Awasthi, A.5
Petersen, T.R.6
-
4
-
-
58149386381
-
The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors
-
D'Alise A.M., Auyeung V., Feuerer M., Nishio J., Fontenot J., Benoist C., et al. The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors. Proc Natl Acad Sci USA 2008, 105:19857-19862.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19857-19862
-
-
D'Alise, A.M.1
Auyeung, V.2
Feuerer, M.3
Nishio, J.4
Fontenot, J.5
Benoist, C.6
-
5
-
-
20944444896
-
Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells
-
You S., Belghith M., Cobbold S., Alyanakian M.A., Gouarin C., Barriot S., et al. Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells. Diabetes 2005, 54:1415-1422.
-
(2005)
Diabetes
, vol.54
, pp. 1415-1422
-
-
You, S.1
Belghith, M.2
Cobbold, S.3
Alyanakian, M.A.4
Gouarin, C.5
Barriot, S.6
-
6
-
-
45949090105
-
Release from regulatory T cell-mediated suppression during the onset of tissue-specific autoimmunity is associated with elevated IL-21
-
Clough L.E., Wang C.J., Schmidt E.M., Booth G., Hou T.Z., Ryan G.A., et al. Release from regulatory T cell-mediated suppression during the onset of tissue-specific autoimmunity is associated with elevated IL-21. J Immunol 2008, 180:5393-5401.
-
(2008)
J Immunol
, vol.180
, pp. 5393-5401
-
-
Clough, L.E.1
Wang, C.J.2
Schmidt, E.M.3
Booth, G.4
Hou, T.Z.5
Ryan, G.A.6
-
7
-
-
0141992907
-
Dynamics of pathogenic and suppressor T cells in autoimmune diabetes development
-
Gregori S., Giarratana N., Smiroldo S., Adorini L. Dynamics of pathogenic and suppressor T cells in autoimmune diabetes development. J Immunol 2003, 171:4040-4047.
-
(2003)
J Immunol
, vol.171
, pp. 4040-4047
-
-
Gregori, S.1
Giarratana, N.2
Smiroldo, S.3
Adorini, L.4
-
8
-
-
17244378876
-
MRL/Mp CD4+,CD25- T cells show reduced sensitivity to suppression by CD4+ CD25+ regulatory T cells in vitro: a novel defect of T cell regulation in systemic lupus erythematosus
-
Monk C.R., Spachidou M., Rovis F., Leung E., Botto M., Lechler R.I., et al. MRL/Mp CD4+,CD25- T cells show reduced sensitivity to suppression by CD4+ CD25+ regulatory T cells in vitro: a novel defect of T cell regulation in systemic lupus erythematosus. Arthritis Rheumat 2005, 52:1180-1184.
-
(2005)
Arthritis Rheumat
, vol.52
, pp. 1180-1184
-
-
Monk, C.R.1
Spachidou, M.2
Rovis, F.3
Leung, E.4
Botto, M.5
Lechler, R.I.6
-
9
-
-
84867581744
-
A validated regulatory network for Th17 cell specification
-
Ciofani M., Madar A., Galan C., Sellars M., Mace K., Pauli F., et al. A validated regulatory network for Th17 cell specification. Cell 2012, 151:289-303.
-
(2012)
Cell
, vol.151
, pp. 289-303
-
-
Ciofani, M.1
Madar, A.2
Galan, C.3
Sellars, M.4
Mace, K.5
Pauli, F.6
-
10
-
-
84876806691
-
Dynamic regulatory network controlling TH17 cell differentiation
-
Yosef N., Shalek A.K., Gaublomme J.T., Jin H., Lee Y., Awasthi A., et al. Dynamic regulatory network controlling TH17 cell differentiation. Nature 2013, 496:461-468.
-
(2013)
Nature
, vol.496
, pp. 461-468
-
-
Yosef, N.1
Shalek, A.K.2
Gaublomme, J.T.3
Jin, H.4
Lee, Y.5
Awasthi, A.6
-
11
-
-
84874220671
-
Gene set enrichment analysis identifies LIF as a negative regulator of human Th2 cell differentiation
-
Ullah U., Tripathi P., Lahesmaa R., Rao K.V. Gene set enrichment analysis identifies LIF as a negative regulator of human Th2 cell differentiation. Sci Rep 2012, 2:464.
-
(2012)
Sci Rep
, vol.2
, pp. 464
-
-
Ullah, U.1
Tripathi, P.2
Lahesmaa, R.3
Rao, K.V.4
-
12
-
-
33646012294
-
T helper cell differentiation: regulation by cis elements and epigenetics
-
Lee G.R., Kim S.T., Spilianakis C.G., Fields P.E., Flavell R.A. T helper cell differentiation: regulation by cis elements and epigenetics. Immunity 2006, 24:369-379.
-
(2006)
Immunity
, vol.24
, pp. 369-379
-
-
Lee, G.R.1
Kim, S.T.2
Spilianakis, C.G.3
Fields, P.E.4
Flavell, R.A.5
-
13
-
-
65349172388
-
Transcriptional regulatory networks in Th17 cell differentiation
-
Zhou L., Littman D.R. Transcriptional regulatory networks in Th17 cell differentiation. Curr Opin Immunol 2009, 21:146-152.
-
(2009)
Curr Opin Immunol
, vol.21
, pp. 146-152
-
-
Zhou, L.1
Littman, D.R.2
-
14
-
-
77958611660
-
Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors
-
Zhu J., Paul W.E. Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors. Immunol Rev 2010, 238:247-262.
-
(2010)
Immunol Rev
, vol.238
, pp. 247-262
-
-
Zhu, J.1
Paul, W.E.2
-
15
-
-
84866532132
-
Induction and molecular signature of pathogenic TH17 cells
-
Lee Y., Awasthi A., Yosef N., Quintana F.J., Xiao S., Peters A., et al. Induction and molecular signature of pathogenic TH17 cells. Nat Immunol 2012, 13:991-999.
-
(2012)
Nat Immunol
, vol.13
, pp. 991-999
-
-
Lee, Y.1
Awasthi, A.2
Yosef, N.3
Quintana, F.J.4
Xiao, S.5
Peters, A.6
-
16
-
-
84860241847
-
Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta
-
Zielinski C.E., Mele F., Aschenbrenner D., Jarrossay D., Ronchi F., Gattorno M., et al. Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta. Nature 2012, 484:514-518.
-
(2012)
Nature
, vol.484
, pp. 514-518
-
-
Zielinski, C.E.1
Mele, F.2
Aschenbrenner, D.3
Jarrossay, D.4
Ronchi, F.5
Gattorno, M.6
-
17
-
-
0036305450
-
T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes
-
Avni O., Lee D., Macian F., Szabo S.J., Glimcher L.H., Rao A. T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat Immunol 2002, 3:643-651.
-
(2002)
Nat Immunol
, vol.3
, pp. 643-651
-
-
Avni, O.1
Lee, D.2
Macian, F.3
Szabo, S.J.4
Glimcher, L.H.5
Rao, A.6
-
18
-
-
77953238901
-
Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage
-
Mukasa R., Balasubramani A., Lee Y.K., Whitley S.K., Weaver B.T., Shibata Y., et al. Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage. Immunity 2010, 32:616-627.
-
(2010)
Immunity
, vol.32
, pp. 616-627
-
-
Mukasa, R.1
Balasubramani, A.2
Lee, Y.K.3
Whitley, S.K.4
Weaver, B.T.5
Shibata, Y.6
-
19
-
-
84864089089
-
Conserved intergenic elements and DNA methylation cooperate to regulate transcription at the il17 locus
-
Thomas R.M., Sai H., Wells A.D. Conserved intergenic elements and DNA methylation cooperate to regulate transcription at the il17 locus. J Biol Chem 2012, 287:25049-25059.
-
(2012)
J Biol Chem
, vol.287
, pp. 25049-25059
-
-
Thomas, R.M.1
Sai, H.2
Wells, A.D.3
-
20
-
-
3042598052
-
Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci
-
Yamashita M., Ukai-Tadenuma M., Miyamoto T., Sugaya K., Hosokawa H., Hasegawa A., et al. Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci. J Biol Chem 2004, 279:26983-26990.
-
(2004)
J Biol Chem
, vol.279
, pp. 26983-26990
-
-
Yamashita, M.1
Ukai-Tadenuma, M.2
Miyamoto, T.3
Sugaya, K.4
Hosokawa, H.5
Hasegawa, A.6
-
21
-
-
46649086595
-
Inactivation of NuRD component Mta2 causes abnormal T cell activation and lupus-like autoimmune disease in mice
-
Lu X., Kovalev G.I., Chang H., Kallin E., Knudsen G., Xia L., et al. Inactivation of NuRD component Mta2 causes abnormal T cell activation and lupus-like autoimmune disease in mice. J Biol Chem 2008, 283:13825-13833.
-
(2008)
J Biol Chem
, vol.283
, pp. 13825-13833
-
-
Lu, X.1
Kovalev, G.I.2
Chang, H.3
Kallin, E.4
Knudsen, G.5
Xia, L.6
-
22
-
-
84928560965
-
Super-enhancers delineate disease-associated regulatory nodes in T cells
-
Vahedi G., Kanno Y., Furumoto Y., Jiang K., Parker S.C., Erdos M.R., et al. Super-enhancers delineate disease-associated regulatory nodes in T cells. Nature 2015, 520:558-562.
-
(2015)
Nature
, vol.520
, pp. 558-562
-
-
Vahedi, G.1
Kanno, Y.2
Furumoto, Y.3
Jiang, K.4
Parker, S.C.5
Erdos, M.R.6
-
23
-
-
84879685794
-
BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis
-
Roychoudhuri R., Hirahara K., Mousavi K., Clever D., Klebanoff C.A., Bonelli M., et al. BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis. Nature 2013, 498:506-510.
-
(2013)
Nature
, vol.498
, pp. 506-510
-
-
Roychoudhuri, R.1
Hirahara, K.2
Mousavi, K.3
Clever, D.4
Klebanoff, C.A.5
Bonelli, M.6
-
24
-
-
84923347358
-
Critical role of histone demethylase Jmjd3 in the regulation of CD4+ T-cell differentiation
-
Li Q., Zou J., Wang M., Ding X., Chepelev I., Zhou X., et al. Critical role of histone demethylase Jmjd3 in the regulation of CD4+ T-cell differentiation. Nat Commun 2014, 5:5780.
-
(2014)
Nat Commun
, vol.5
, pp. 5780
-
-
Li, Q.1
Zou, J.2
Wang, M.3
Ding, X.4
Chepelev, I.5
Zhou, X.6
-
25
-
-
84895155334
-
Epigenetics in 2013. DNA methylation and miRNA: key roles in systemic autoimmunity
-
Richardson B.C., Patel D.R. Epigenetics in 2013. DNA methylation and miRNA: key roles in systemic autoimmunity. Nat Rev Rheumatol 2014, 10:72-74.
-
(2014)
Nat Rev Rheumatol
, vol.10
, pp. 72-74
-
-
Richardson, B.C.1
Patel, D.R.2
-
26
-
-
84878361920
-
Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naive CD4+ T cells from lupus patients
-
Coit P., Jeffries M., Altorok N., Dozmorov M.G., Koelsch K.A., Wren J.D., et al. Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naive CD4+ T cells from lupus patients. J Autoimmun 2013, 43:78-84.
-
(2013)
J Autoimmun
, vol.43
, pp. 78-84
-
-
Coit, P.1
Jeffries, M.2
Altorok, N.3
Dozmorov, M.G.4
Koelsch, K.A.5
Wren, J.D.6
-
27
-
-
83355166923
-
Tsokos GC. cAMP-responsive element modulator (CREM)alpha protein induces interleukin 17A expression and mediates epigenetic alterations at the interleukin-17A gene locus in patients with systemic lupus erythematosus
-
Rauen T., Hedrich C.M., Juang Y.T., Tenbrock K. Tsokos GC. cAMP-responsive element modulator (CREM)alpha protein induces interleukin 17A expression and mediates epigenetic alterations at the interleukin-17A gene locus in patients with systemic lupus erythematosus. J Biol Chem 2011, 286:43437-43446.
-
(2011)
J Biol Chem
, vol.286
, pp. 43437-43446
-
-
Rauen, T.1
Hedrich, C.M.2
Juang, Y.T.3
Tenbrock, K.4
-
28
-
-
84856880805
-
Tsokos GC. cAMP-responsive element modulator alpha (CREMalpha) suppresses IL-17F protein expression in T lymphocytes from patients with systemic lupus erythematosus (SLE)
-
Hedrich C.M., Rauen T., Kis-Toth K., Kyttaris V.C. Tsokos GC. cAMP-responsive element modulator alpha (CREMalpha) suppresses IL-17F protein expression in T lymphocytes from patients with systemic lupus erythematosus (SLE). J Biol Chem 2012, 287:4715-4725.
-
(2012)
J Biol Chem
, vol.287
, pp. 4715-4725
-
-
Hedrich, C.M.1
Rauen, T.2
Kis-Toth, K.3
Kyttaris, V.C.4
-
29
-
-
84923326765
-
Genetic and epigenetic fine mapping of causal autoimmune disease variants
-
Farh K.K., Marson A., Zhu J., Kleinewietfeld M., Housley W.J., Beik S., et al. Genetic and epigenetic fine mapping of causal autoimmune disease variants. Nature 2015, 518:337-343.
-
(2015)
Nature
, vol.518
, pp. 337-343
-
-
Farh, K.K.1
Marson, A.2
Zhu, J.3
Kleinewietfeld, M.4
Housley, W.J.5
Beik, S.6
-
30
-
-
84904644906
-
Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility
-
Seumois G., Chavez L., Gerasimova A., Lienhard M., Omran N., Kalinke L., et al. Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility. Nat Immunol 2014, 15:777-788.
-
(2014)
Nat Immunol
, vol.15
, pp. 777-788
-
-
Seumois, G.1
Chavez, L.2
Gerasimova, A.3
Lienhard, M.4
Omran, N.5
Kalinke, L.6
-
32
-
-
0027474296
-
Metabolic changes in activated T cells: an NMR study of human peripheral blood lymphocytes
-
Bental M., Deutsch C. Metabolic changes in activated T cells: an NMR study of human peripheral blood lymphocytes. Magn Reson Med 1993, 29:317-326.
-
(1993)
Magn Reson Med
, vol.29
, pp. 317-326
-
-
Bental, M.1
Deutsch, C.2
-
33
-
-
84878831880
-
Posttranscriptional control of T cell effector function by aerobic glycolysis
-
Chang C.H., Curtis J.D., Maggi L.B., Faubert B., Villarino A.V., O'Sullivan D., et al. Posttranscriptional control of T cell effector function by aerobic glycolysis. Cell 2013, 153:1239-1251.
-
(2013)
Cell
, vol.153
, pp. 1239-1251
-
-
Chang, C.H.1
Curtis, J.D.2
Maggi, L.B.3
Faubert, B.4
Villarino, A.V.5
O'Sullivan, D.6
-
35
-
-
79953172571
-
Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets
-
Michalek R.D., Gerriets V.A., Jacobs S.R., Macintyre A.N., MacIver N.J., Mason E.F., et al. Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets. J Immunol 2011, 186:3299-3303.
-
(2011)
J Immunol
, vol.186
, pp. 3299-3303
-
-
Michalek, R.D.1
Gerriets, V.A.2
Jacobs, S.R.3
Macintyre, A.N.4
MacIver, N.J.5
Mason, E.F.6
-
36
-
-
84255199079
-
The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation
-
Wang R., Dillon C.P., Shi L.Z., Milasta S., Carter R., Finkelstein D., et al. The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. Immunity 2011, 35:871-882.
-
(2011)
Immunity
, vol.35
, pp. 871-882
-
-
Wang, R.1
Dillon, C.P.2
Shi, L.Z.3
Milasta, S.4
Carter, R.5
Finkelstein, D.6
-
37
-
-
84867010006
-
C-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells
-
Nie Z., Hu G., Wei G., Cui K., Yamane A., Resch W., et al. c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells. Cell 2012, 151:68-79.
-
(2012)
Cell
, vol.151
, pp. 68-79
-
-
Nie, Z.1
Hu, G.2
Wei, G.3
Cui, K.4
Yamane, A.5
Resch, W.6
-
38
-
-
84904057246
-
The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function
-
Macintyre A.N., Gerriets V.A., Nichols A.G., Michalek R.D., Rudolph M.C., Deoliveira D., et al. The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function. Cell Metab 2014, 20:61-72.
-
(2014)
Cell Metab
, vol.20
, pp. 61-72
-
-
Macintyre, A.N.1
Gerriets, V.A.2
Nichols, A.G.3
Michalek, R.D.4
Rudolph, M.C.5
Deoliveira, D.6
-
39
-
-
84922080059
-
De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells
-
Berod L., Friedrich C., Nandan A., Freitag J., Hagemann S., Harmrolfs K., et al. De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells. Nat Med 2014, 20:1327-1333.
-
(2014)
Nat Med
, vol.20
, pp. 1327-1333
-
-
Berod, L.1
Friedrich, C.2
Nandan, A.3
Freitag, J.4
Hagemann, S.5
Harmrolfs, K.6
-
40
-
-
80052277906
-
Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1
-
Dang E.V., Barbi J., Yang H.Y., Jinasena D., Yu H., Zheng Y., et al. Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1. Cell 2011, 146:772-784.
-
(2011)
Cell
, vol.146
, pp. 772-784
-
-
Dang, E.V.1
Barbi, J.2
Yang, H.Y.3
Jinasena, D.4
Yu, H.5
Zheng, Y.6
-
41
-
-
79960369458
-
HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
-
Shi L.Z., Wang R., Huang G., Vogel P., Neale G., Green D.R., et al. HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells. J Exp Med 2011, 208:1367-1376.
-
(2011)
J Exp Med
, vol.208
, pp. 1367-1376
-
-
Shi, L.Z.1
Wang, R.2
Huang, G.3
Vogel, P.4
Neale, G.5
Green, D.R.6
-
42
-
-
79952985551
-
The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2
-
Delgoffe G.M., Pollizzi K.N., Waickman A.T., Heikamp E., Meyers D.J., Horton M.R., et al. The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2. Nat Immunol 2011, 12:295-303.
-
(2011)
Nat Immunol
, vol.12
, pp. 295-303
-
-
Delgoffe, G.M.1
Pollizzi, K.N.2
Waickman, A.T.3
Heikamp, E.4
Meyers, D.J.5
Horton, M.R.6
-
43
-
-
66749107425
-
Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response
-
Sundrud M.S., Koralov S.B., Feuerer M., Calado D.P., Kozhaya A.E., Rhule-Smith A., et al. Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response. Science 2009, 324:1334-1338.
-
(2009)
Science
, vol.324
, pp. 1334-1338
-
-
Sundrud, M.S.1
Koralov, S.B.2
Feuerer, M.3
Calado, D.P.4
Kozhaya, A.E.5
Rhule-Smith, A.6
-
44
-
-
84876514626
-
Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation
-
Sinclair L.V., Rolf J., Emslie E., Shi Y.B., Taylor P.M., Cantrell D.A. Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation. Nat Immunol 2013, 14:500-508.
-
(2013)
Nat Immunol
, vol.14
, pp. 500-508
-
-
Sinclair, L.V.1
Rolf, J.2
Emslie, E.3
Shi, Y.B.4
Taylor, P.M.5
Cantrell, D.A.6
-
45
-
-
46149098344
-
LXR signaling couples sterol metabolism to proliferation in the acquired immune response
-
Bensinger S.J., Bradley M.N., Joseph S.B., Zelcer N., Janssen E.M., Hausner M.A., et al. LXR signaling couples sterol metabolism to proliferation in the acquired immune response. Cell 2008, 134:97-111.
-
(2008)
Cell
, vol.134
, pp. 97-111
-
-
Bensinger, S.J.1
Bradley, M.N.2
Joseph, S.B.3
Zelcer, N.4
Janssen, E.M.5
Hausner, M.A.6
-
46
-
-
79551545978
-
Liver X receptor (LXR) mediates negative regulation of mouse and human Th17 differentiation
-
Cui G., Qin X., Wu L., Zhang Y., Sheng X., Yu Q., et al. Liver X receptor (LXR) mediates negative regulation of mouse and human Th17 differentiation. J Clin Invest 2011, 121:658-670.
-
(2011)
J Clin Invest
, vol.121
, pp. 658-670
-
-
Cui, G.1
Qin, X.2
Wu, L.3
Zhang, Y.4
Sheng, X.5
Yu, Q.6
-
47
-
-
77953243855
-
A second class of nuclear receptors for oxysterols: regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol)
-
Wang Y., Kumar N., Crumbley C., Griffin P.R., Burris T.P. A second class of nuclear receptors for oxysterols: regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol). Biochim Biophys Acta 2010, 1801:917-923.
-
(2010)
Biochim Biophys Acta
, vol.1801
, pp. 917-923
-
-
Wang, Y.1
Kumar, N.2
Crumbley, C.3
Griffin, P.R.4
Burris, T.P.5
-
48
-
-
77951149298
-
Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands
-
Wang Y., Kumar N., Solt L.A., Richardson T.I., Helvering L.M., Crumbley C., et al. Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands. J Biol Chem 2010, 285:5013-5025.
-
(2010)
J Biol Chem
, vol.285
, pp. 5013-5025
-
-
Wang, Y.1
Kumar, N.2
Solt, L.A.3
Richardson, T.I.4
Helvering, L.M.5
Crumbley, C.6
-
49
-
-
77954844606
-
Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma
-
Jin L., Martynowski D., Zheng S., Wada T., Xie W., Li Y. Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma. Mol Endocrinol 2010, 24:923-929.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 923-929
-
-
Jin, L.1
Martynowski, D.2
Zheng, S.3
Wada, T.4
Xie, W.5
Li, Y.6
-
50
-
-
84928057028
-
Sterol metabolism controls T(H)17 differentiation by generating endogenous RORgamma agonists
-
Hu X., Wang Y., Hao L.Y., Liu X., Lesch C.A., Sanchez B.M., et al. Sterol metabolism controls T(H)17 differentiation by generating endogenous RORgamma agonists. Nat Chem Biol 2015, 11:141-147.
-
(2015)
Nat Chem Biol
, vol.11
, pp. 141-147
-
-
Hu, X.1
Wang, Y.2
Hao, L.Y.3
Liu, X.4
Lesch, C.A.5
Sanchez, B.M.6
-
51
-
-
84922901154
-
Identification of natural RORgamma ligands that regulate the development of lymphoid cells
-
Santori F.R., Huang P., van de Pavert S.A., Douglass E.F., Leaver D.J., Haubrich B.A., et al. Identification of natural RORgamma ligands that regulate the development of lymphoid cells. Cell Metab 2015, 21:286-297.
-
(2015)
Cell Metab
, vol.21
, pp. 286-297
-
-
Santori, F.R.1
Huang, P.2
van de Pavert, S.A.3
Douglass, E.F.4
Leaver, D.J.5
Haubrich, B.A.6
|