-
1
-
-
33744984785
-
Th17: An effector CD4 T cell lineage with regulatory T cell ties
-
Weaver, C. T., Harrington, L. E., Mangan, P. R., Gavrieli, M. & Murphy, K. M. Th17: an effector CD4 T cell lineage with regulatory T cell ties. Immunity 24, 677-688 (2006).
-
(2006)
Immunity
, vol.24
, pp. 677-688
-
-
Weaver, C.T.1
Harrington, L.E.2
Mangan, P.R.3
Gavrieli, M.4
Murphy, K.M.5
-
2
-
-
77952313777
-
Differentiation of effector CD4 T cell populations
-
Zhu, J., Yamane, H. & Paul, W. E. Differentiation of effector CD4 T cell populations. Annu. Rev. Immunol. 28, 445-489 (2010).
-
(2010)
Annu. Rev. Immunol.
, vol.28
, pp. 445-489
-
-
Zhu, J.1
Yamane, H.2
Paul, W.E.3
-
3
-
-
27544490377
-
Interleukin 17-producing CD4\+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington, L. E. et al. Interleukin 17-producing CD4\+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat. Immunol. 6, 1123-1132 (2005).
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
-
4
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park, H. et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat. Immunol. 6, 1133-1141 (2005).
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1133-1141
-
-
Park, H.1
-
5
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17\+ T helper cells
-
Ivanov, I. I. et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17\+ T helper cells. Cell 126, 1121-1133 (2006).
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
-
6
-
-
37849048599
-
T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma
-
Yang, X. O. et al. T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. Immunity 28, 29-39 (2008).
-
(2008)
Immunity
, vol.28
, pp. 29-39
-
-
Yang, X.O.1
-
7
-
-
84859416933
-
Regulatory T cells: Mechanisms of differentiation and function
-
Josefowicz, S. Z., Lu, L. F. & Rudensky, A. Y. Regulatory T cells: mechanisms of differentiation and function. Annu. Rev. Immunol. 30, 531-564 (2012).
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 531-564
-
-
Josefowicz, S.Z.1
Lu, L.F.2
Rudensky, A.Y.3
-
8
-
-
77954141914
-
FOXP3\+ regulatory T cells in the human immune system
-
Sakaguchi, S., Miyara, M., Costantino, C. M. & Hafler, D. A. FOXP3\+ regulatory T cells in the human immune system. Nat. Rev. Immunol. 10, 490-500 (2010).
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 490-500
-
-
Sakaguchi, S.1
Miyara, M.2
Costantino, C.M.3
Hafler, D.A.4
-
9
-
-
33847647528
-
Regulatory T cells and cancer
-
Wang, H. Y. & Wang, R. F. Regulatory T cells and cancer. Curr. Opin. Immunol. 19, 217-223 (2007).
-
(2007)
Curr. Opin. Immunol.
, vol.19
, pp. 217-223
-
-
Wang, H.Y.1
Wang, R.F.2
-
10
-
-
0034919646
-
The role of MHC class II-restricted tumor antigens and CD4\+ T cells in antitumor immunity
-
Wang, R. F. The role of MHC class II-restricted tumor antigens and CD4\+ T cells in antitumor immunity. Trends Immunol. 22, 269-276 (2001).
-
(2001)
Trends Immunol.
, vol.22
, pp. 269-276
-
-
Wang, R.F.1
-
11
-
-
77950196277
-
T(H) 17 cells in tumour immunity and immunotherapy
-
Zou, W. & Restifo, N. P. T(H)17 cells in tumour immunity and immunotherapy. Nat. Rev. Immunol. 10, 248-256 (2010).
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 248-256
-
-
Zou, W.1
Restifo, N.P.2
-
12
-
-
0141955150
-
T cell rewiring in differentiation and disease
-
Krishnan, S., Farber, D. L. & Tsokos, G. C. T cell rewiring in differentiation and disease. J. Immunol. 171, 3325-3331 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 3325-3331
-
-
Krishnan, S.1
Farber, D.L.2
Tsokos, G.C.3
-
13
-
-
80052027515
-
Effector T-cell subsets in systemic lupus erythematosus: Update focusing on Th17 cells
-
Shin, M. S., Lee, N. & Kang, I. Effector T-cell subsets in systemic lupus erythematosus: update focusing on Th17 cells. Curr. Opin. Rheumatol. 23, 444-448 (2011).
-
(2011)
Curr. Opin. Rheumatol.
, vol.23
, pp. 444-448
-
-
Shin, M.S.1
Lee, N.2
Kang, I.3
-
14
-
-
80054967360
-
Myelodysplastic syndromes: The role of the immune system in pathogenesis
-
Warlick, E. D. & Miller, J. S. Myelodysplastic syndromes: the role of the immune system in pathogenesis. Leuk. Lymphoma 52, 2045-2049 (2011).
-
(2011)
Leuk. Lymphoma
, vol.52
, pp. 2045-2049
-
-
Warlick, E.D.1
Miller, J.S.2
-
15
-
-
79953134246
-
Genomic views of STAT function in CD4\+ T helper cell differentiation
-
O'Shea, J. J., Lahesmaa, R., Vahedi, G., Laurence, A. & Kanno, Y. Genomic views of STAT function in CD4\+ T helper cell differentiation. Nat. Rev. Immunol. 11, 239-250 (2011).
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 239-250
-
-
O'Shea, J.J.1
Lahesmaa, R.2
Vahedi, G.3
Laurence, A.4
Kanno, Y.5
-
16
-
-
84859401055
-
Transcriptional and epigenetic control of T helper cell specification: Molecular mechanisms underlying commitment and plasticity
-
Kanno, Y., Vahedi, G., Hirahara, K., Singleton, K. & O'Shea, J. J. Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity. Annu. Rev. Immunol. 30, 707-731 (2012).
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 707-731
-
-
Kanno, Y.1
Vahedi, G.2
Hirahara, K.3
Singleton, K.4
O'Shea, J.J.5
-
17
-
-
84887549060
-
The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(\+) T helper type 1 and type 2 cells
-
Tumes, D. J. et al. The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(\+) T helper type 1 and type 2 cells. Immunity 39, 819-832 (2013).
-
(2013)
Immunity
, vol.39
, pp. 819-832
-
-
Tumes, D.J.1
-
18
-
-
58149214356
-
Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4\+ T cells
-
Wei, G. et al. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4\+ T cells. Immunity 30, 155-167 (2009).
-
(2009)
Immunity
, vol.30
, pp. 155-167
-
-
Wei, G.1
-
19
-
-
58849092225
-
Epigenetic control of T-helper-cell differentiation
-
Wilson, C. B., Rowell, E. & Sekimata, M. Epigenetic control of T-helper-cell differentiation. Nat. Rev. Immunol. 9, 91-105 (2009).
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 91-105
-
-
Wilson, C.B.1
Rowell, E.2
Sekimata, M.3
-
20
-
-
80051885764
-
Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types
-
Wei, G. et al. Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types. Immunity 35, 299-311 (2011).
-
(2011)
Immunity
, vol.35
, pp. 299-311
-
-
Wei, G.1
-
21
-
-
77953995002
-
Covalent histone modifications-miswritten, misinterpreted and mis-erased in human cancers
-
Chi, P., Allis, C. D. & Wang, G. G. Covalent histone modifications-miswritten, misinterpreted and mis-erased in human cancers. Nat. Rev. Cancer 10, 457-469 (2010).
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 457-469
-
-
Chi, P.1
Allis, C.D.2
Wang, G.G.3
-
22
-
-
43249102851
-
Erasing the methyl mark: Histone demethylases at the center of cellular differentiation and disease
-
Cloos, P. A., Christensen, J., Agger, K. & Helin, K. Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease. Genes Dev. 22, 1115-1140 (2008).
-
(2008)
Genes Dev.
, vol.22
, pp. 1115-1140
-
-
Cloos, P.A.1
Christensen, J.2
Agger, K.3
Helin, K.4
-
23
-
-
33947513027
-
Regulation of histone methylation by demethylimination and demethylation
-
Klose, R. J. & Zhang, Y. Regulation of histone methylation by demethylimination and demethylation. Nat. Rev. Mol. Cell Biol. 8, 307-318 (2007).
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 307-318
-
-
Klose, R.J.1
Zhang, Y.2
-
24
-
-
78751662908
-
The Polycomb complex PRC2 and its mark in life
-
Margueron, R. & Reinberg, D. The Polycomb complex PRC2 and its mark in life. Nature 469, 343-349 (2011).
-
(2011)
Nature
, vol.469
, pp. 343-349
-
-
Margueron, R.1
Reinberg, D.2
-
25
-
-
77953644347
-
Reversal of histone methylation: Biochemical and molecular mechanisms of histone demethylases
-
Mosammaparast, N. & Shi, Y. Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases. Annu. Rev. Biochem. 79, 155-179 (2010).
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 155-179
-
-
Mosammaparast, N.1
Shi, Y.2
-
26
-
-
0036830642
-
Role of histone H3 lysine 27 methylation in Polycomb-group silencing
-
Cao, R. et al. Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 298, 1039-1043 (2002).
-
(2002)
Science
, vol.298
, pp. 1039-1043
-
-
Cao, R.1
-
27
-
-
35148867907
-
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
-
Agger, K. et al. UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature 449, 731-734 (2007).
-
(2007)
Nature
, vol.449
, pp. 731-734
-
-
Agger, K.1
-
28
-
-
36749082438
-
Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases
-
Hong, S. et al. Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases. Proc. Natl Acad. Sci. USA 104, 18439-18444 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 18439-18444
-
-
Hong, S.1
-
29
-
-
36248990248
-
SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron
-
Jepsen, K. et al. SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron. Nature 450, 415-419 (2007).
-
(2007)
Nature
, vol.450
, pp. 415-419
-
-
Jepsen, K.1
-
30
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides, T. Chromatin modifications and their function. Cell 128, 693-705 (2007).
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
31
-
-
35148898348
-
A histone H3 lysine 27 demethylase regulates animal posterior development
-
Lan, F. et al. A histone H3 lysine 27 demethylase regulates animal posterior development. Nature 449, 689-694 (2007).
-
(2007)
Nature
, vol.449
, pp. 689-694
-
-
Lan, F.1
-
32
-
-
84905454845
-
Stage-dependent and locus-specific role of histone demethylase jumonji D3 (JMJD3) in the embryonic stages of lung development
-
Li, Q. et al. Stage-dependent and locus-specific role of histone demethylase jumonji D3 (JMJD3) in the embryonic stages of lung development. PLoS Genet. 10, e1004524 (2014).
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004524
-
-
Li, Q.1
-
33
-
-
66149138053
-
The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene-and stressinduced senescence
-
Agger, K. et al. The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene-and stressinduced senescence. Genes Dev. 23, 1171-1176 (2009).
-
(2009)
Genes Dev.
, vol.23
, pp. 1171-1176
-
-
Agger, K.1
-
34
-
-
66149135288
-
Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS
-
Barradas, M. et al. Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS. Genes Dev. 23, 1177-1182 (2009).
-
(2009)
Genes Dev.
, vol.23
, pp. 1177-1182
-
-
Barradas, M.1
-
35
-
-
77956634439
-
Nodal signaling recruits the histone demethylase Jmjd3 to counteract polycomb-mediated repression at target genes
-
Dahle, O., Kumar, A. & Kuehn, M. R. Nodal signaling recruits the histone demethylase Jmjd3 to counteract polycomb-mediated repression at target genes. Sci. Signal. 3, ra48 (2010).
-
(2010)
Sci. Signal.
, vol.3
, pp. 48
-
-
Dahle, O.1
Kumar, A.2
Kuehn, M.R.3
-
36
-
-
81255147963
-
KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells
-
Pereira, F. et al. KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells. Hum. Mol. Genet. 20, 4655-4665 (2011).
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 4655-4665
-
-
Pereira, F.1
-
37
-
-
77956954197
-
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
-
Satoh, T. et al. The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. Nat. Immunol. 11, 936-944 (2010).
-
(2010)
Nat. Immunol.
, vol.11
, pp. 936-944
-
-
Satoh, T.1
-
38
-
-
70350435962
-
Epigenetic regulation of the alternatively activated macrophage phenotype
-
Ishii, M. et al. Epigenetic regulation of the alternatively activated macrophage phenotype. Blood 114, 3244-3254 (2009).
-
(2009)
Blood
, vol.114
, pp. 3244-3254
-
-
Ishii, M.1
-
39
-
-
55749090506
-
Coordinated but physically separable interaction with H3K27-demethylase and H3K4-methyltransferase activities are required for T-box protein-mediated activation of developmental gene expression
-
Miller, S. A., Huang, A. C., Miazgowicz, M. M., Brassil, M. M. & Weinmann, A. S. Coordinated but physically separable interaction with H3K27-demethylase and H3K4-methyltransferase activities are required for T-box protein-mediated activation of developmental gene expression. Genes Dev. 22, 2980-2993 (2008).
-
(2008)
Genes Dev.
, vol.22
, pp. 2980-2993
-
-
Miller, S.A.1
Huang, A.C.2
Miazgowicz, M.M.3
Brassil, M.M.4
Weinmann, A.S.5
-
40
-
-
78649263390
-
Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression
-
Miller, S. A., Mohn, S. E. & Weinmann, A. S. Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression. Mol. Cell 40, 594-605 (2010).
-
(2010)
Mol. Cell
, vol.40
, pp. 594-605
-
-
Miller, S.A.1
Mohn, S.E.2
Weinmann, A.S.3
-
41
-
-
84874789264
-
Jmjd3 inhibits reprogramming by upregulating expression of INK4a/Arf and targeting PHF20 for ubiquitination
-
Zhao, W. et al. Jmjd3 inhibits reprogramming by upregulating expression of INK4a/Arf and targeting PHF20 for ubiquitination. Cell 152, 1037-1050 (2013).
-
(2013)
Cell
, vol.152
, pp. 1037-1050
-
-
Zhao, W.1
-
42
-
-
79960919901
-
Control of TH17 cells occurs in the small intestine
-
Esplugues, E. et al. Control of TH17 cells occurs in the small intestine. Nature 475, 514-518 (2011).
-
(2011)
Nature
, vol.475
, pp. 514-518
-
-
Esplugues, E.1
-
43
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo, S. J. et al. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100, 655-669 (2000).
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
-
44
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski, A. et al. High-resolution profiling of histone methylations in the human genome. Cell 129, 823-837 (2007).
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
-
45
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein, B. E. et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125, 315-326 (2006).
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
-
46
-
-
72149124496
-
Smad3 differentially regulates the induction of regulatory and inflammatory T cell differentiation
-
Martinez, G. J. et al. Smad3 differentially regulates the induction of regulatory and inflammatory T cell differentiation. J. Biol. Chem. 284, 35283-35286 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 35283-35286
-
-
Martinez, G.J.1
-
47
-
-
84863724616
-
An epigenetic silencing pathway controlling T helper 2 cell lineage commitment
-
Allan, R. S. et al. An epigenetic silencing pathway controlling T helper 2 cell lineage commitment. Nature 487, 249-253 (2012).
-
(2012)
Nature
, vol.487
, pp. 249-253
-
-
Allan, R.S.1
-
48
-
-
84255174663
-
Control of B cell development by the histone H2A deubiquitinase MYSM1
-
Jiang, X. X. et al. Control of B cell development by the histone H2A deubiquitinase MYSM1. Immunity 35, 883-896 (2011).
-
(2011)
Immunity
, vol.35
, pp. 883-896
-
-
Jiang, X.X.1
-
49
-
-
33646586637
-
Crucial role of MLL for the maintenance of memory T helper type 2 cell responses
-
Yamashita, M. et al. Crucial role of MLL for the maintenance of memory T helper type 2 cell responses. Immunity 24, 611-622 (2006).
-
(2006)
Immunity
, vol.24
, pp. 611-622
-
-
Yamashita, M.1
-
50
-
-
84884820418
-
Jmjd3 controls mesodermal and cardiovascular differentiation of embryonic stem cells
-
Ohtani, K. et al. Jmjd3 controls mesodermal and cardiovascular differentiation of embryonic stem cells. Circ. Res. 113, 856-862 (2013).
-
(2013)
Circ. Res.
, vol.113
, pp. 856-862
-
-
Ohtani, K.1
-
51
-
-
84880086292
-
Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation
-
Pham, D. et al. Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation. J. Immunol. 191, 902-911 (2013).
-
(2013)
J. Immunol.
, vol.191
, pp. 902-911
-
-
Pham, D.1
-
52
-
-
84862622207
-
The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation
-
Chen, S. et al. The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation. Genes Dev. 26, 1364-1375 (2012).
-
(2012)
Genes Dev.
, vol.26
, pp. 1364-1375
-
-
Chen, S.1
-
53
-
-
84873369257
-
RNA polymerase II progression through H3K27me3-enriched gene bodies requires JMJD3 histone demethylase
-
Estaras, C., Fueyo, R., Akizu, N., Beltran, S. & Martinez-Balbas, M. A. RNA polymerase II progression through H3K27me3-enriched gene bodies requires JMJD3 histone demethylase. Mol. Biol. Cell 24, 351-360 (2013).
-
(2013)
Mol. Biol. Cell
, vol.24
, pp. 351-360
-
-
Estaras, C.1
Fueyo, R.2
Akizu, N.3
Beltran, S.4
Martinez-Balbas, M.A.5
-
54
-
-
0000751148
-
Isolation of mouse small intestinal intraepithelial lymphocytes Peyer's patch, and lamina propria cells
-
Lefrancois, L. & Lycke, N. Isolation of mouse small intestinal intraepithelial lymphocytes, Peyer's patch, and lamina propria cells. Curr. Protoc. Immunol. Chapter 3, Unit 3, 19 (2001).
-
(2001)
Curr. Protoc. Immunol. Chapter 3, Unit
, vol.3
, pp. 19
-
-
Lefrancois, L.1
Lycke, N.2
-
55
-
-
77954957901
-
Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development
-
Qi, H. H. et al. Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature 466, 503-507 (2010).
-
(2010)
Nature
, vol.466
, pp. 503-507
-
-
Qi, H.H.1
-
56
-
-
75249095274
-
DEGseq: An R package for identifying differentially expressed genes from RNA-seq data
-
Wang, L., Feng, Z., Wang, X. & Zhang, X. DEGseq: an R package for identifying differentially expressed genes from RNA-seq data. Bioinformatics 26, 136-138 (2010).
-
(2010)
Bioinformatics
, vol.26
, pp. 136-138
-
-
Wang, L.1
Feng, Z.2
Wang, X.3
Zhang, X.4
|