-
1
-
-
61949472508
-
Innate immune recognition of infected apoptotic cells directs Th17 cell differentiation
-
Torchinsky, M. B., Garaude, J., Martin, A. P., and Blander, J. M. (2009) Innate immune recognition of infected apoptotic cells directs Th17 cell differentiation. Nature 458, 78-82
-
(2009)
Nature
, vol.458
, pp. 78-82
-
-
Torchinsky, M.B.1
Garaude, J.2
Martin, A.P.3
Blander, J.M.4
-
2
-
-
79951743212
-
Functional specialization of interleukin-17 family members
-
Iwakura, Y., Ishigame, H., Saijo, S., and Nakae, S. (2011) Functional specialization of interleukin-17 family members. Immunity 34, 149-162
-
(2011)
Immunity
, vol.34
, pp. 149-162
-
-
Iwakura, Y.1
Ishigame, H.2
Saijo, S.3
Nakae, S.4
-
3
-
-
78649689761
-
Signal transduction pathways and transcriptional regulation in Th17 cell differentiation
-
Hirahara, K., Ghoreschi, K., Laurence, A., Yang, X. P., Kanno, Y., and O'Shea, J. J. (2010) Signal transduction pathways and transcriptional regulation in Th17 cell differentiation. Cytokine Growth Factor Rev. 21, 425-434
-
(2010)
Cytokine Growth Factor Rev.
, vol.21
, pp. 425-434
-
-
Hirahara, K.1
Ghoreschi, K.2
Laurence, A.3
Yang, X.P.4
Kanno, Y.5
O'Shea, J.J.6
-
4
-
-
45449086449
-
Long-range regulation of cytokine gene expression
-
Rowell, E., Merkenschlager, M., and Wilson, C. B. (2008) Long-range regulation of cytokine gene expression. Curr. Opin. Immunol. 20, 272-280
-
(2008)
Curr. Opin. Immunol.
, vol.20
, pp. 272-280
-
-
Rowell, E.1
Merkenschlager, M.2
Wilson, C.B.3
-
5
-
-
54549100120
-
Interactions among the transcription factors Runx1, RORγt, and Foxp3 regulate the differentiation of interleukin 17-producing T cells
-
Zhang, F., Meng, G., and Strober, W. (2008) Interactions among the transcription factors Runx1, RORγt, and Foxp3 regulate the differentiation of interleukin 17-producing T cells. Nat. Immunol. 9, 1297-1306
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1297-1306
-
-
Zhang, F.1
Meng, G.2
Strober, W.3
-
6
-
-
0035656305
-
DNA Methylation Is a Critical Cell-Intrinsic Determinant of Astrocyte Differentiation in the Fetal Brain
-
DOI 10.1016/S1534-5807(01)00101-0, PII S1534580701001010
-
Takizawa, T., Nakashima, K., Namihira, M., Ochiai, W., Uemura, A., Yanagisawa, M., Fujita, N., Nakao, M., and Taga, T. (2001) DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain. Dev. Cell 1, 749-758 (Pubitemid 33586130)
-
(2001)
Developmental Cell
, vol.1
, Issue.6
, pp. 749-758
-
-
Takizawa, T.1
Nakashima, K.2
Namihira, M.3
Ochiai, W.4
Uemura, A.5
Yanagisawa, M.6
Fujita, N.7
Nakao, M.8
Taga, T.9
-
7
-
-
0033529704
-
Stat3 as an oncogene
-
DOI 10.1016/S0092-8674(00)81959-5
-
Bromberg, J. F., Wrzeszczynska, M. H., Devgan, G., Zhao, Y., Pestell, R. G., Albanese, C., and Darnell, J. E. (1999) Stat3 as an oncogene. Cell 98, 295-303 (Pubitemid 29380565)
-
(1999)
Cell
, vol.98
, Issue.3
, pp. 295-303
-
-
Bromberg, J.F.1
Wrzeszczynska, M.H.2
Devgan, G.3
Zhao, Y.4
Pestell, R.G.5
Albanese, C.6
Darnell Jr., J.E.7
-
8
-
-
17044410174
-
Signals from CD28 induce stable epigenetic modification of the IL-2 promoter
-
Thomas, R. M., Gao, L., and Wells, A. D. (2005) Signals from CD28 induce stable epigenetic modification of the IL-2 promoter. J. Immunol. 174, 4639-4646
-
(2005)
J. Immunol.
, vol.174
, pp. 4639-4646
-
-
Thomas, R.M.1
Gao, L.2
Wells, A.D.3
-
9
-
-
33745861718
-
Epigenetic remodeling of the IL-2 and IFN-γ loci in memory CD8 T cells is influenced by CD4 T cells
-
Northrop, J. K., Thomas, R. M., Wells, A. D., and Shen, H. (2006) Epigenetic remodeling of the IL-2 and IFNγ loci in memory CD8 T cells is influenced by CD4 T cells. J. Immunol. 177, 1062-1069 (Pubitemid 44036608)
-
(2006)
Journal of Immunology
, vol.177
, Issue.2
, pp. 1062-1069
-
-
Northrop, J.K.1
Thomas, R.M.2
Wells, A.D.3
Shen, H.4
-
11
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
DOI 10.1084/jem.20041257
-
Langrish, C. L., Chen, Y., Blumenschein, W. M., Mattson, J., Basham, B., Sedgwick, J. D., McClanahan, T., Kastelein, R. A., and Cua, D. J. (2005) IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med. 201, 233-240 (Pubitemid 40189432)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.2
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
Kastelein, R.A.8
Cua, D.J.9
-
12
-
-
33646397611
-
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
-
Yen, D., Cheung, J., Scheerens, H., Poulet, F., McClanahan, T., McKenzie, B., Kleinschek, M. A., Owyang, A., Mattson, J., Blumenschein, W., Murphy, E., Sathe, M., Cua, D. J., Kastelein, R. A., and Rennick, D. (2006) IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J. Clin. Invest. 116, 1310-1316
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1310-1316
-
-
Yen, D.1
Cheung, J.2
Scheerens, H.3
Poulet, F.4
McClanahan, T.5
McKenzie, B.6
Kleinschek, M.A.7
Owyang, A.8
Mattson, J.9
Blumenschein, W.10
Murphy, E.11
Sathe, M.12
Cua, D.J.13
Kastelein, R.A.14
Rennick, D.15
-
13
-
-
79952534189
-
Regulation of chromatin by histone modifications
-
Bannister, A. J., and Kouzarides, T. (2011) Regulation of chromatin by histone modifications. Cell Res. 21, 381-395
-
(2011)
Cell Res.
, vol.21
, pp. 381-395
-
-
Bannister, A.J.1
Kouzarides, T.2
-
14
-
-
77953238901
-
Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage
-
Mukasa, R., Balasubramani, A., Lee, Y. K., Whitley, S. K., Weaver, B. T., Shibata, Y., Crawford, G. E., Hatton, R. D., and Weaver, C. T. (2010) Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage. Immunity 32, 616-627
-
(2010)
Immunity
, vol.32
, pp. 616-627
-
-
Mukasa, R.1
Balasubramani, A.2
Lee, Y.K.3
Whitley, S.K.4
Weaver, B.T.5
Shibata, Y.6
Crawford, G.E.7
Hatton, R.D.8
Weaver, C.T.9
-
15
-
-
34147138648
-
Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation
-
DOI 10.1074/jbc.C600322200
-
Akimzhanov, A. M., Yang, X. O., and Dong, C. (2007) Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation. J. Biol. Chem. 282, 5969-5972 (Pubitemid 47100812)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.9
, pp. 5969-5972
-
-
Akimzhanov, A.M.1
Yang, X.O.2
Dong, C.3
-
16
-
-
58149214356
-
+ T cells
-
+ T cells. Immunity 30, 155-167
-
(2009)
Immunity
, vol.30
, pp. 155-167
-
-
Wei, G.1
Wei, L.2
Zhu, J.3
Zang, C.4
Hu-Li, J.5
Yao, Z.6
Cui, K.7
Kanno, Y.8
Roh, T.Y.9
Watford, W.T.10
Schones, D.E.11
Peng, W.12
Sun, H.W.13
Paul, W.E.14
O'Shea, J.J.15
Zhao, K.16
-
17
-
-
47749124186
-
Foxp3 inhibits RORγt-mediated IL-17A mRNA transcription through direct interaction with RORγt
-
Ichiyama, K., Yoshida, H., Wakabayashi, Y., Chinen, T., Saeki, K., Nakaya, M., Takaesu, G., Hori, S., Yoshimura, A., and Kobayashi, T. (2008) Foxp3 inhibits RORγt-mediated IL-17A mRNA transcription through direct interaction with RORγt. J. Biol. Chem. 283, 17003-17008
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 17003-17008
-
-
Ichiyama, K.1
Yoshida, H.2
Wakabayashi, Y.3
Chinen, T.4
Saeki, K.5
Nakaya, M.6
Takaesu, G.7
Hori, S.8
Yoshimura, A.9
Kobayashi, T.10
-
18
-
-
34247593586
-
STAT3 regulates cytokine-mediated generation of inflammatory helper T cells
-
DOI 10.1074/jbc.C600321200
-
Yang, X. O., Panopoulos, A. D., Nurieva, R., Chang, S. H., Wang, D., Watowich, S. S., and Dong, C. (2007) STAT3 regulates cytokine-mediated generation of inflammatory helper T cells. J. Biol. Chem. 282, 9358-9363 (Pubitemid 47104613)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.13
, pp. 9358-9363
-
-
Yang, X.O.1
Panopoulos, A.D.2
Nurieva, R.3
Seon, H.C.4
Wang, D.5
Watowich, S.S.6
Dong, C.7
-
19
-
-
34547188748
-
H-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
DOI 10.1038/ni1488, PII NI1488
-
Zhou, L., Ivanov, I. I., Spolski, R., Min, R., Shenderov, K., Egawa, T., Levy, D. E., Leonard, W. J., and Littman, D. R. (2007) IL-6 programs Th17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat. Immunol. 8, 967-974 (Pubitemid 47300011)
-
(2007)
Nature Immunology
, vol.8
, Issue.9
, pp. 967-974
-
-
Zhou, L.1
Ivanov, I.I.2
Spolski, R.3
Min, R.4
Shenderov, K.5
Egawa, T.6
Levy, D.E.7
Leonard, W.J.8
Littman, D.R.9
-
20
-
-
79951682333
-
Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5
-
Yang, X. P., Ghoreschi, K., Steward-Tharp, S. M., Rodriguez-Canales, J., Zhu, J., Grainger, J. R., Hirahara, K., Sun, H. W., Wei, L., Vahedi, G., Kanno, Y., O'Shea, J. J., and Laurence, A. (2011) Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5. Nat. Immunol. 12, 247-254
-
(2011)
Nat. Immunol.
, vol.12
, pp. 247-254
-
-
Yang, X.P.1
Ghoreschi, K.2
Steward-Tharp, S.M.3
Rodriguez-Canales, J.4
Zhu, J.5
Grainger, J.R.6
Hirahara, K.7
Sun, H.W.8
Wei, L.9
Vahedi, G.10
Kanno, Y.11
O'Shea, J.J.12
Laurence, A.13
-
21
-
-
37849048599
-
T helper 17 lineage differentiation is programmed by orphan nuclear receptors RORα and RORγ
-
Yang, X. O., Pappu, B. P., Nurieva, R., Akimzhanov, A., Kang, H. S., Chung, Y., Ma, L., Shah, B., Panopoulos, A. D., Schluns, K. S., Watowich, S. S., Tian, Q., Jetten, A. M., and Dong, C. (2008) T helper 17 lineage differentiation is programmed by orphan nuclear receptors RORα and RORγ. Immunity 28, 29-39
-
(2008)
Immunity
, vol.28
, pp. 29-39
-
-
Yang, X.O.1
Pappu, B.P.2
Nurieva, R.3
Akimzhanov, A.4
Kang, H.S.5
Chung, Y.6
Ma, L.7
Shah, B.8
Panopoulos, A.D.9
Schluns, K.S.10
Watowich, S.S.11
Tian, Q.12
Jetten, A.M.13
Dong, C.14
-
22
-
-
0032901199
-
Cytosine methylation and mammalian development
-
Walsh, C. P., and Bestor, T. H. (1999) Cytosine methylation and mammalian development. Genes Dev. 13, 26-34 (Pubitemid 29045113)
-
(1999)
Genes and Development
, vol.13
, Issue.1
, pp. 26-34
-
-
Walsh, C.P.1
Bestor, T.H.2
-
23
-
-
0029069145
-
Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
-
Schindler, C., and Darnell, J. E. (1995) Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu. Rev. Biochem. 64, 621-651
-
(1995)
Annu. Rev. Biochem.
, vol.64
, pp. 621-651
-
-
Schindler, C.1
Darnell, J.E.2
-
24
-
-
33744479688
-
Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells
-
DOI 10.1073/pnas.0600666103
-
Chen, Z., Laurence, A., Kanno, Y., Pacher-Zavisin, M., Zhu, B. M., Tato, C., Yoshimura, A., Hennighausen, L., and O'Shea, J. J. (2006) Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells. Proc. Natl. Acad. Sci. U.S.A. 103, 8137-8142 (Pubitemid 43801065)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.21
, pp. 8137-8142
-
-
Chen, Z.1
Laurence, A.2
Kanno, Y.3
Pacher-Zavisin, M.4
Zhu, B.-M.5
Tato, C.6
Yoshimura, A.7
Hennighausen, L.8
O'Shea, J.J.9
-
25
-
-
0028943484
-
Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4
-
Jacobson, N. G., Szabo, S. J., Weber-Nordt, R. M., Zhong, Z., Schreiber, R. D., Darnell, J. E., Jr., and Murphy, K. M. (1995) Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4. J. Exp. Med. 181, 1755-1762
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1755-1762
-
-
Jacobson, N.G.1
Szabo, S.J.2
Weber-Nordt, R.M.3
Zhong, Z.4
Schreiber, R.D.5
Darnell Jr., J.E.6
Murphy, K.M.7
-
26
-
-
79951677394
-
Fate mapping of IL-17-producing T cells in inflammatory responses
-
Hirota, K., Duarte, J. H., Veldhoen, M., Hornsby, E., Li, Y., Cua, D. J., Ahlfors, H., Wilhelm, C., Tolaini, M., Menzel, U., Garefalaki, A., Potocnik, A. J., and Stockinger, B. (2011) Fate mapping of IL-17-producing T cells in inflammatory responses. Nat. Immunol. 12, 255-263
-
(2011)
Nat. Immunol.
, vol.12
, pp. 255-263
-
-
Hirota, K.1
Duarte, J.H.2
Veldhoen, M.3
Hornsby, E.4
Li, Y.5
Cua, D.J.6
Ahlfors, H.7
Wilhelm, C.8
Tolaini, M.9
Menzel, U.10
Garefalaki, A.11
Potocnik, A.J.12
Stockinger, B.13
-
27
-
-
33644854871
-
A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory
-
DOI 10.1038/sj.emboj.7601012, PII 7601012
-
Murayama, A., Sakura, K., Nakama, M., Yasuzawa-Tanaka, K., Fujita, E., Tateishi, Y., Wang, Y., Ushijima, T., Baba, T., Shibuya, K., Shibuya, A., Kawabe, Y., and Yanagisawa, J. (2006) A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory. EMBO J. 25, 1081-1092 (Pubitemid 43372121)
-
(2006)
EMBO Journal
, vol.25
, Issue.5
, pp. 1081-1092
-
-
Murayama, A.1
Sakura, K.2
Nakama, M.3
Yasuzawa-Tanaka, K.4
Fujita, E.5
Tateishi, Y.6
Wang, Y.7
Ushijima, T.8
Baba, T.9
Shibuya, K.10
Shibuya, A.11
Kawabe, Y.-I.12
Yanagisawa, J.13
-
28
-
-
67651001561
-
The AP-1 transcription factor Batf controls Th17 differentiation
-
Schraml, B. U., Hildner, K., Ise, W., Lee, W. L., Smith, W. A., Solomon, B., Sahota, G., Sim, J., Mukasa, R., Cemerski, S., Hatton, R. D., Stormo, G. D., Weaver, C. T., Russell, J. H., Murphy, T. L., and Murphy, K. M. (2009) The AP-1 transcription factor Batf controls Th17 differentiation. Nature 460, 405-409
-
(2009)
Nature
, vol.460
, pp. 405-409
-
-
Schraml, B.U.1
Hildner, K.2
Ise, W.3
Lee, W.L.4
Smith, W.A.5
Solomon, B.6
Sahota, G.7
Sim, J.8
Mukasa, R.9
Cemerski, S.10
Hatton, R.D.11
Stormo, G.D.12
Weaver, C.T.13
Russell, J.H.14
Murphy, T.L.15
Murphy, K.M.16
|