Leptin's metabolic and immune functions can be uncoupled at the ligand/receptor interaction level

Cellular and Molecular Life Sciences

Volumn 72, Issue 3, 2015, Pages 629-644

  Zabeau, Lennart ^a   Jensen, Cathy J ^b,f   Seeuws, Sylvie ^c   Venken, Koen ^c   Verhee, Annick ^a   Catteeuw, Dominiek ^a   Van Loo, Geert ^a   Chen, Hui ^d   Walder, Ken ^e   Hollis, Jacob ^f   Foote, Simon ^g   Morris, Margaret J ^d   Van Der Heyden, José ^a   Peelman, Frank ^a   Oldfield, Brian J ^f   Rubio, Justin P ^b   Elewaut, Dirk ^c   Tavernier, Jan ^a  

^a GHENT UNIVERSITY   (Belgium)

^b FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^c GHENT UNIVERSITY HOSPITAL   (Belgium)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e DEAKIN UNIVERSITY   (Australia)

^f MONASH UNIVERSITY   (Australia)

^g UNIVERSITY OF TASMANIA   (Australia)

Author keywords

Antagonist; Autoimmune disease; Genetic model; Leptin receptor; Metabolism; Nanobody; Obesity

Indexed keywords

LEPTIN; LEPTIN RECEPTOR; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; PRIMER DNA;

ANALYSIS OF VARIANCE; ANIMAL; CHEMICALLY INDUCED; DNA SEQUENCE; EXPERIMENTAL ARTHRITIS; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FLOW CYTOMETRY; GENE DELETION; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOLOGY; MALE; MCF 7 CELL LINE; METABOLISM; MOLECULAR GENETICS; MOUSE; MUTANT MOUSE STRAIN; NUCLEOTIDE SEQUENCE; PATHOLOGY; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TOXIC HEPATITIS; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; ARTHRITIS, EXPERIMENTAL; BASE SEQUENCE; BLOTTING, WESTERN; DNA PRIMERS; DRUG-INDUCED LIVER INJURY; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FLOW CYTOMETRY; HEK293 CELLS; HUMANS; LEPTIN; MALE; MCF-7 CELLS; MICE; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, LEPTIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION;

EID: 84939883849     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-014-1697-x     Document Type: Article

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