A new missense mutation in the leptin gene causes mild obesity and hypogonadism without affecting T cell responsiveness

Journal of Clinical Endocrinology and Metabolism

Volumn 95, Issue 6, 2010, Pages 2836-2840

  Fischer Posovszky, Pamela ^a   Von Schnurbein, Julia ^a   Moepps, Barbara ^a   Lahr, Georgia ^a   Strauss, Gudrun ^a   Barth, Thomas F ^a   Kassubek, Jan ^a   Mühleder, Hannes ^b   Möller, Peter ^a   Debatin, Klaus Michael ^a   Gierschik, Peter ^a   Wabitsch, Martin ^a  

^a UNIVERSITY OF ULM   (Germany)

^b Hospital of Wels   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; BETA ACTIN; IMMUNOGLOBULIN LIGHT CHAIN; LEPTIN; LEUCINE; MUTANT PROTEIN; COMPLEMENTARY DNA; CYTOKINE; DIAGNOSTIC AGENT;

ADIPOCYTE; ADIPOSE TISSUE; ADOLESCENT; ARTICLE; AUSTRIA; BODY MASS; CASE REPORT; CELL STRAIN HEK293; CONGENITAL LEPTIN DEFICIENCY; DISEASE SEVERITY; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; EXON; FEMALE; GENE; HOMOZYGOSITY; HORMONE DEFICIENCY; HUMAN; HUMAN CELL; HYPERPHAGIA; HYPOGONADISM; HYPOGONADOTROPIC HYPOGONADISM; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LEAN BODY WEIGHT; LEPTIN GENE; MISSENSE MUTATION; OB GENE; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; WESTERN BLOTTING; BLOOD; CALORIC INTAKE; CALORIMETRY; CELL PROLIFERATION; CHEMISTRY; COLD; DIET THERAPY; EATING; ENERGY METABOLISM; GENETIC TRANSFECTION; GENETICS; MOLECULAR CLONING; MOTOR ACTIVITY; PHYSIOLOGY; PRESSURE;

ADIPOSITY; ADOLESCENT; BLOTTING, WESTERN; CALORIMETRY, INDIRECT; CELL PROLIFERATION; CLONING, MOLECULAR; COLD TEMPERATURE; CYTOKINES; DNA, COMPLEMENTARY; EATING; ENERGY INTAKE; ENERGY METABOLISM; FEMALE; HUMANS; HYPOGONADISM; IMMUNOHISTOCHEMISTRY; LEPTIN; MOTOR ACTIVITY; MUTATION, MISSENSE; OBESITY; PRESSURE; T-LYMPHOCYTES; TRANSFECTION;

EID: 77954461979     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2009-2466     Document Type: Article

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