메뉴 건너뛰기




Volumn 9, Issue 1, 2013, Pages 88-100

Metabonomic investigation of rat tissues following intravenous administration of cyanidin 3-glucoside at a physiologically relevant dose

Author keywords

Anthocyanins; Cyanidin 3 glucoside; Metabolomics; Metabonomics; Quadrupole time of flight mass spectrometry; Ultra performance liquid chromatography; Wistar rats

Indexed keywords

ALPHA TOCOPHEROL; ARACHIDONIC ACID; BILE ACID; CYANIDIN 3 GLUCOSIDE; GLUTATHIONE; GLUTATHIONE DISULFIDE; PHOSPHATIDYLETHANOLAMINE; TAUROCHOLIC ACID;

EID: 84872662432     PISSN: 15733882     EISSN: 15733890     Source Type: Journal    
DOI: 10.1007/s11306-012-0430-8     Document Type: Article
Times cited : (15)

References (67)
  • 1
    • 21344468638 scopus 로고    scopus 로고
    • Quantification and characterisation of cyclo-oxygenase and lipid peroxidation inhibitory anthocyanins in fruits of Amelanchier
    • Adhikari, D. P., Francis, J. A., Schutzki, R. E., Chandra, A., & Nair, M. G. (2005). Quantification and characterisation of cyclo-oxygenase and lipid peroxidation inhibitory anthocyanins in fruits of Amelanchier. Phytochemical Analysis, 16(3), 175-180.
    • (2005) Phytochemical Analysis , vol.16 , Issue.3 , pp. 175-180
    • Adhikari, D.P.1    Francis, J.A.2    Schutzki, R.E.3    Chandra, A.4    Nair, M.G.5
  • 2
    • 84868351733 scopus 로고    scopus 로고
    • NMR spectroscopy and chemometrics as a tool for anti-TNFα activity screening in crude extracts of grapes and other berries
    • doi: 10. 1007/s11306-012-0406-8
    • Ali, K., Iqbal, M., Korthout, H., Maltese, F., Fortes, A., Pais, M., et al. (2012). NMR spectroscopy and chemometrics as a tool for anti-TNFα activity screening in crude extracts of grapes and other berries. Metabolomics. doi: 10. 1007/s11306-012-0406-8.
    • (2012) Metabolomics
    • Ali, K.1    Iqbal, M.2    Korthout, H.3    Maltese, F.4    Fortes, A.5    Pais, M.6
  • 3
    • 34548404574 scopus 로고    scopus 로고
    • Absorption, transport, and tissue delivery of vitamin E
    • Attilio, R. (2007). Absorption, transport, and tissue delivery of vitamin E. Molecular Aspects of Medicine, 28(5-6), 423-436.
    • (2007) Molecular Aspects of Medicine , vol.28 , Issue.5-6 , pp. 423-436
    • Attilio, R.1
  • 5
    • 77953673295 scopus 로고    scopus 로고
    • Berries: emerging impact on cardiovascular health
    • Basu, A., Rhone, M., & Lyons, T. J. (2010). Berries: emerging impact on cardiovascular health. Nutrition Reviews, 68(3), 168-177.
    • (2010) Nutrition Reviews , vol.68 , Issue.3 , pp. 168-177
    • Basu, A.1    Rhone, M.2    Lyons, T.J.3
  • 9
    • 21244436700 scopus 로고    scopus 로고
    • Performance of some variable selection methods when multicollinearity is present
    • Chong, I.-G., & Jun, C.-H. (2005). Performance of some variable selection methods when multicollinearity is present. Chemometrics and Intelligent Laboratory Systems, 78(1-2), 103-112.
    • (2005) Chemometrics and Intelligent Laboratory Systems , vol.78 , Issue.1-2 , pp. 103-112
    • Chong, I.-G.1    Jun, C.-H.2
  • 10
    • 38949209075 scopus 로고    scopus 로고
    • NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology
    • Coen, M., Holmes, E., Lindon, J. C., & Nicholson, J. K. (2008). NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology. Chemical Research in Toxicology, 21(1), 9-27.
    • (2008) Chemical Research in Toxicology , vol.21 , Issue.1 , pp. 9-27
    • Coen, M.1    Holmes, E.2    Lindon, J.C.3    Nicholson, J.K.4
  • 11
    • 33745897902 scopus 로고    scopus 로고
    • Transport of glutathione and glutathione conjugates by MRP1
    • Cole, S. P. C., & Deeley, R. G. (2006). Transport of glutathione and glutathione conjugates by MRP1. Trends in Pharmacological Sciences, 27(8), 438-446.
    • (2006) Trends in Pharmacological Sciences , vol.27 , Issue.8 , pp. 438-446
    • Cole, S.P.C.1    Deeley, R.G.2
  • 12
    • 77954660699 scopus 로고    scopus 로고
    • Getting the mOST from OST: Role of organic solute transporter, OSTα-OSTβ, in bile acid and steroid metabolism
    • Dawson, P. A., Hubbert, M. L., & Rao, A. (2010). Getting the mOST from OST: Role of organic solute transporter, OSTα-OSTβ, in bile acid and steroid metabolism. Biochimica et Biophysica Acta, 1801(9), 994-1004.
    • (2010) Biochimica Et Biophysica Acta , vol.1801 , Issue.9 , pp. 994-1004
    • Dawson, P.A.1    Hubbert, M.L.2    Rao, A.3
  • 13
    • 34248512719 scopus 로고    scopus 로고
    • Untargeted large-scale plant metabolomics using liquid chromatography coupled to mass spectrometry
    • De Vos, R. C. H., Moco, S., Lommen, A., Keurentjes, J. J. B., Bino, R. J., & Hall, R. D. (2007). Untargeted large-scale plant metabolomics using liquid chromatography coupled to mass spectrometry. Nature Protocols, 2(4), 778-791.
    • (2007) Nature Protocols , vol.2 , Issue.4 , pp. 778-791
    • de Vos, R.C.H.1    Moco, S.2    Lommen, A.3    Keurentjes, J.J.B.4    Bino, R.J.5    Hall, R.D.6
  • 15
    • 77955085206 scopus 로고    scopus 로고
    • Diagnostic performance of traditional hepatobiliary biomarkers of drug-induced liver injury in the rat
    • Ennulat, D., Magid-Slav, M., Rehm, S., & Tatsuoka, K. S. (2010). Diagnostic performance of traditional hepatobiliary biomarkers of drug-induced liver injury in the rat. Toxicological Sciences, 116(2), 397-412.
    • (2010) Toxicological Sciences , vol.116 , Issue.2 , pp. 397-412
    • Ennulat, D.1    Magid-Slav, M.2    Rehm, S.3    Tatsuoka, K.S.4
  • 16
    • 0034959944 scopus 로고    scopus 로고
    • Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks
    • Fiehn, O. (2001). Combining genomics, metabolome analysis, and biochemical modelling to understand metabolic networks. Comparative and Functional Genomics, 2(3), 155-168.
    • (2001) Comparative and Functional Genomics , vol.2 , Issue.3 , pp. 155-168
    • Fiehn, O.1
  • 17
    • 0036007687 scopus 로고    scopus 로고
    • Metabolomics-The link between genotypes and phenotypes
    • Fiehn, O. (2002). Metabolomics-The link between genotypes and phenotypes. Plant Molecular Biology, 48(1), 155-171.
    • (2002) Plant Molecular Biology , vol.48 , Issue.1 , pp. 155-171
    • Fiehn, O.1
  • 18
    • 79960540465 scopus 로고    scopus 로고
    • Sample preparation prior to the LC-MS-based metabolomics/metabonomics of blood-derived samples
    • Gika, H., & Theodoridis, G. (2011). Sample preparation prior to the LC-MS-based metabolomics/metabonomics of blood-derived samples. Bioanalysis, 3(14), 1647-1661.
    • (2011) Bioanalysis , vol.3 , Issue.14 , pp. 1647-1661
    • Gika, H.1    Theodoridis, G.2
  • 20
    • 0027504187 scopus 로고
    • Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen Elderly Study
    • Hertog, M. G., Feskens, E. J., Hollman, P. C., Katan, M. B., & Kromhout, D. (1993). Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen Elderly Study. Lancet, 342(8878), 1007-1011.
    • (1993) Lancet , vol.342 , Issue.8878 , pp. 1007-1011
    • Hertog, M.G.1    Feskens, E.J.2    Hollman, P.C.3    Katan, M.B.4    Kromhout, D.5
  • 21
    • 84872665438 scopus 로고    scopus 로고
    • Bioavailability and metabolic fate of anthocyanins. Functional food and health
    • Ichiyanagi, T. (2008). Bioavailability and metabolic fate of anthocyanins. Functional food and health. ACS Symposium Series, 993, 48-61.
    • (2008) ACS Symposium Series , vol.993 , pp. 48-61
    • Ichiyanagi, T.1
  • 23
    • 33746835408 scopus 로고    scopus 로고
    • Aspects of anthocyanin absorption, metabolism and pharmacokinetics in humans
    • Kay, C. D. (2006). Aspects of anthocyanin absorption, metabolism and pharmacokinetics in humans. Nutrition Research Reviews, 19(01), 137-146.
    • (2006) Nutrition Research Reviews , vol.19 , Issue.1 , pp. 137-146
    • Kay, C.D.1
  • 24
    • 79953010953 scopus 로고    scopus 로고
    • What are the obstacles for an integrated system for comprehensive interpretation of cross-platform metabolic profile data?
    • Kind, T., & Fiehn, O. (2009). What are the obstacles for an integrated system for comprehensive interpretation of cross-platform metabolic profile data? Bioanalysis, 1(9), 1511-1514.
    • (2009) Bioanalysis , vol.1 , Issue.9 , pp. 1511-1514
    • Kind, T.1    Fiehn, O.2
  • 25
    • 77949398878 scopus 로고    scopus 로고
    • Xenobiotic, bile acid, and cholesterol transporters: function and regulation
    • Klaassen, C. D., & Aleksunes, L. M. (2010). Xenobiotic, bile acid, and cholesterol transporters: function and regulation. Pharmacological Reviews, 62(1), 1-96.
    • (2010) Pharmacological Reviews , vol.62 , Issue.1 , pp. 1-96
    • Klaassen, C.D.1    Aleksunes, L.M.2
  • 26
    • 10744221414 scopus 로고    scopus 로고
    • Evaluation of hepatotoxic potential of drugs by inhibition of bile-acid transport in cultured primary human hepatocytes and intact rats
    • Kostrubsky, V. E., Strom, S. C., Hanson, J., Urda, E., Rose, K., Burliegh, J., et al. (2003). Evaluation of hepatotoxic potential of drugs by inhibition of bile-acid transport in cultured primary human hepatocytes and intact rats. Toxicological Sciences, 76(1), 220-228.
    • (2003) Toxicological Sciences , vol.76 , Issue.1 , pp. 220-228
    • Kostrubsky, V.E.1    Strom, S.C.2    Hanson, J.3    Urda, E.4    Rose, K.5    Burliegh, J.6
  • 28
    • 58249110568 scopus 로고    scopus 로고
    • Role of bile acids and bile acid receptors in metabolic regulation
    • Lefebvre, P., Cariou, B., Lien, F., Kuipers, F., & Staels, B. (2009). Role of bile acids and bile acid receptors in metabolic regulation. Physiological Reviews, 89(1), 147-191.
    • (2009) Physiological Reviews , vol.89 , Issue.1 , pp. 147-191
    • Lefebvre, P.1    Cariou, B.2    Lien, F.3    Kuipers, F.4    Staels, B.5
  • 30
    • 4043089112 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of dietary flavonoids in humans
    • Manach, C., & Donovan, J. L. (2004). Pharmacokinetics and metabolism of dietary flavonoids in humans. Free Radical Research, 38(8), 771-785.
    • (2004) Free Radical Research , vol.38 , Issue.8 , pp. 771-785
    • Manach, C.1    Donovan, J.L.2
  • 32
    • 77956586799 scopus 로고    scopus 로고
    • Optimization and evaluation of metabolite extraction protocols for untargeted metabolic profiling of liver samples by UPLC-MS
    • Masson, P., Alves, A. C., Ebbels, T. M. D., Nicholson, J. K., & Want, E. J. (2010). Optimization and evaluation of metabolite extraction protocols for untargeted metabolic profiling of liver samples by UPLC-MS. Analytical Chemistry, 82(18), 7779-7786.
    • (2010) Analytical Chemistry , vol.82 , Issue.18 , pp. 7779-7786
    • Masson, P.1    Alves, A.C.2    Ebbels, T.M.D.3    Nicholson, J.K.4    Want, E.J.5
  • 33
    • 34447540210 scopus 로고    scopus 로고
    • The bioavailability and absorption of anthocyanins: Towards a better understanding
    • McGhie, T. K., & Walton, M. C. (2007). The bioavailability and absorption of anthocyanins: Towards a better understanding. Molecular Nutrition & Food Research, 51(6), 702-713.
    • (2007) Molecular Nutrition & Food Research , vol.51 , Issue.6 , pp. 702-713
    • McGhie, T.K.1    Walton, M.C.2
  • 35
    • 79958852716 scopus 로고    scopus 로고
    • Changes in the metabolic profile of rat liver after α-tocopherol deficiency as revealed by metabolomics analysis
    • Moazzami, A. A., Andersson, R., & Kamal-Eldin, A. (2011). Changes in the metabolic profile of rat liver after α-tocopherol deficiency as revealed by metabolomics analysis. NMR in Biomedicine, 24(5), 499-505.
    • (2011) NMR in Biomedicine , vol.24 , Issue.5 , pp. 499-505
    • Moazzami, A.A.1    Andersson, R.2    Kamal-Eldin, A.3
  • 37
    • 46049112249 scopus 로고    scopus 로고
    • Intake of flavonoids and risk of cancer in Finnish men: The Kuopio Ischaemic Heart Disease Risk Factor Study
    • Mursu, J., Nurmi, T., Tuomainen, T.-P., Salonen, J. T., Pukkala, E., & Voutilainen, S. (2008). Intake of flavonoids and risk of cancer in Finnish men: The Kuopio Ischaemic Heart Disease Risk Factor Study. International Journal of Cancer, 123(3), 660-663.
    • (2008) International Journal of Cancer , vol.123 , Issue.3 , pp. 660-663
    • Mursu, J.1    Nurmi, T.2    Tuomainen, T.-P.3    Salonen, J.T.4    Pukkala, E.5    Voutilainen, S.6
  • 38
    • 0032694577 scopus 로고    scopus 로고
    • Metabonomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
    • Nicholson, J. K., Lindon, J. C., & Holmes, E. (1999). 'Metabonomics': Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica, 29(11), 1181-1189.
    • (1999) Xenobiotica , vol.29 , Issue.11 , pp. 1181-1189
    • Nicholson, J.K.1    Lindon, J.C.2    Holmes, E.3
  • 39
    • 0043286281 scopus 로고    scopus 로고
    • Fruits and vegetables in the prevention of cellular oxidative damage
    • Prior, R. L. (2003). Fruits and vegetables in the prevention of cellular oxidative damage. American Journal of Clinical Nutrition, 78(3 Suppl.), 570S-578S.
    • (2003) American Journal of Clinical Nutrition , vol.78 , Issue.3 SUPPL.
    • Prior, R.L.1
  • 40
    • 0036890295 scopus 로고    scopus 로고
    • Increase in renal glutathione in cholestatic liver disease is due to a direct effect of bile acids
    • Purucker, E., Marschall, H.-U., Geier, A., Gartung, C., & Matern, S. (2002). Increase in renal glutathione in cholestatic liver disease is due to a direct effect of bile acids. American Journal of Physiology, 283(6), F1281-F1289.
    • (2002) American Journal of Physiology , vol.283 , Issue.6
    • Purucker, E.1    Marschall, H.-U.2    Geier, A.3    Gartung, C.4    Matern, S.5
  • 42
    • 20544466649 scopus 로고    scopus 로고
    • Metabonomics in toxicology: A review
    • Robertson, D. G. (2005). Metabonomics in toxicology: A review. Toxicological Sciences, 85(2), 809-822.
    • (2005) Toxicological Sciences , vol.85 , Issue.2 , pp. 809-822
    • Robertson, D.G.1
  • 43
    • 84855875727 scopus 로고    scopus 로고
    • Procedure for tissue sample preparation and metabolite extraction for high-throughput targeted metabolomics
    • doi: 10. 1007/s11306-011-0293-4
    • Römisch-Margl, W., Prehn, C., Bogumil, R., Röhring, C., Suhre, K., & Adamski, J. (2011). Procedure for tissue sample preparation and metabolite extraction for high-throughput targeted metabolomics. Metabolomics, 1-10. doi: 10. 1007/s11306-011-0293-4.
    • (2011) Metabolomics , pp. 1-10
    • Römisch-Margl, W.1    Prehn, C.2    Bogumil, R.3    Röhring, C.4    Suhre, K.5    Adamski, J.6
  • 44
    • 78650907092 scopus 로고    scopus 로고
    • Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology: A review
    • Roux, A., Lison, D., Junot, C., & Heilier, J.-F. (2011). Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology: A review. Clinical Biochemistry, 44(1), 119-135.
    • (2011) Clinical Biochemistry , vol.44 , Issue.1 , pp. 119-135
    • Roux, A.1    Lison, D.2    Junot, C.3    Heilier, J.-F.4
  • 45
    • 48749121080 scopus 로고    scopus 로고
    • A sample extraction and chromatographic strategy for increasing LC/MS detection coverage of the erythrocyte metabolome
    • Sana, T. R., Waddell, K., & Fischer, S. M. (2008). A sample extraction and chromatographic strategy for increasing LC/MS detection coverage of the erythrocyte metabolome. Journal of Chromatography B, 871(2), 314-321.
    • (2008) Journal of Chromatography B , vol.871 , Issue.2 , pp. 314-321
    • Sana, T.R.1    Waddell, K.2    Fischer, S.M.3
  • 46
    • 74449085466 scopus 로고    scopus 로고
    • Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research
    • Scalbert, A., Brennan, L., Fiehn, O., Hankemeier, T., Kristal, B., van Ommen, B., et al. (2009). Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research. Metabolomics, 5(4), 435-458.
    • (2009) Metabolomics , vol.5 , Issue.4 , pp. 435-458
    • Scalbert, A.1    Brennan, L.2    Fiehn, O.3    Hankemeier, T.4    Kristal, B.5    van Ommen, B.6
  • 47
    • 77955133915 scopus 로고    scopus 로고
    • Evaluation of sampling and extraction methodologies for the global metabolic profiling of Saccharophagus degradans
    • Shin, M. H., Lee, D. Y., Liu, K.-H., Fiehn, O., & Kim, K. H. (2010). Evaluation of sampling and extraction methodologies for the global metabolic profiling of Saccharophagus degradans. Analytical Chemistry, 82(15), 6660-6666.
    • (2010) Analytical Chemistry , vol.82 , Issue.15 , pp. 6660-6666
    • Shin, M.H.1    Lee, D.Y.2    Liu, K.-H.3    Fiehn, O.4    Kim, K.H.5
  • 48
    • 57449116347 scopus 로고    scopus 로고
    • Anthocyanin/polyphenolic-rich fruit juice reduces oxidative cell damage in an intervention study with patients on hemodialysis
    • Spormann, T. M., Albert, F. W., Rath, T., Dietrich, H., Will, F., Stockis, J.-P., et al. (2008). Anthocyanin/polyphenolic-rich fruit juice reduces oxidative cell damage in an intervention study with patients on hemodialysis. Cancer Epidemiology, Biomarkers and Prevention, 17(12), 3372-3380.
    • (2008) Cancer Epidemiology, Biomarkers and Prevention , vol.17 , Issue.12 , pp. 3372-3380
    • Spormann, T.M.1    Albert, F.W.2    Rath, T.3    Dietrich, H.4    Will, F.5    Stockis, J.-P.6
  • 51
    • 84857781822 scopus 로고    scopus 로고
    • LC-MS based global metabolite profiling of grapes: solvent extraction protocol optimisation
    • Theodoridis, G., Gika, H., Franceschi, P., Caputi, L., Arapitsas, P., Scholz, M., et al. (2012). LC-MS based global metabolite profiling of grapes: solvent extraction protocol optimisation. Metabolomics, 8(2), 175-185.
    • (2012) Metabolomics , vol.8 , Issue.2 , pp. 175-185
    • Theodoridis, G.1    Gika, H.2    Franceschi, P.3    Caputi, L.4    Arapitsas, P.5    Scholz, M.6
  • 53
    • 0036083139 scopus 로고    scopus 로고
    • Orthogonal projections to latent structures (O-PLS)
    • Trygg, J., & Wold, S. (2002). Orthogonal projections to latent structures (O-PLS). Journal of Chemometrics, 16(3), 119-128.
    • (2002) Journal of Chemometrics , vol.16 , Issue.3 , pp. 119-128
    • Trygg, J.1    Wold, S.2
  • 54
    • 0141738858 scopus 로고    scopus 로고
    • U. S. Department of Agriculture, A. R. S, Accessed May 4, 2011, from
    • U. S. Department of Agriculture, A. R. S. (2007). USDA Database for the flavonoid content of selected Foods, Release 2. 1. Accessed May 4, 2011, from http://www. nal. usda. gov/fnic/foodcomp/Data/Flav/Flav02-1. pdf.
    • (2007) USDA Database for the flavonoid content of selected Foods, Release 2. 1
  • 55
    • 79952741343 scopus 로고    scopus 로고
    • U. S. Department of Health & Human services, & U. S. Department of Agriculture, Accessed Oct 3, 2011 from
    • U. S. Department of Health & Human services, & U. S. Department of Agriculture (2010). Dietary Guidelines for Americans, 2010. Accessed Oct 3, 2011 from http://health. gov/dietaryguidelines/dga2010/DietaryGuidelines2010. pdf.
    • (2010) Dietary Guidelines for Americans, 2010
  • 56
    • 79957850339 scopus 로고    scopus 로고
    • Exceptionally fast uptake and metabolism of cyanidin 3-glucoside by rat kidneys and liver
    • Vanzo, A., Vrhovsek, U., Tramer, F., Mattivi, F., & Passamonti, S. (2011). Exceptionally fast uptake and metabolism of cyanidin 3-glucoside by rat kidneys and liver. Journal of Natural Products, 74(5), 1049-1054.
    • (2011) Journal of Natural Products , vol.74 , Issue.5 , pp. 1049-1054
    • Vanzo, A.1    Vrhovsek, U.2    Tramer, F.3    Mattivi, F.4    Passamonti, S.5
  • 57
    • 84889475179 scopus 로고    scopus 로고
    • Sampling and sample preparation
    • In S. G. Villas-Bôas, U. Roessner, M. A. E. Hansen, J. Smedsgaard, & J. Nielsen (Eds.), New Yersey: Wiley
    • Villas-Bôas, S. G. (2006). Sampling and sample preparation. In S. G. Villas-Bôas, U. Roessner, M. A. E. Hansen, J. Smedsgaard, & J. Nielsen (Eds.), Metabolome analysis: An introduction (pp. 39-82). New Yersey: Wiley.
    • (2006) Metabolome analysis: An introduction , pp. 39-82
    • Villas-Bôas, S.G.1
  • 58
    • 4644312251 scopus 로고    scopus 로고
    • WHO, Accessed September 2, 2011, from
    • WHO (2004). Global strategy on diet, physical activity and health. Accessed September 2, 2011, from http://www. who. int/dietphysicalactivity/strategy/eb11344/strategy_english_web. pdf.
    • (2004) Global strategy on diet, physical activity and health
  • 59
    • 41149120242 scopus 로고    scopus 로고
    • Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models
    • Wiklund, S., Johansson, E., Sjostrom, L., Mellerowicz, E. J., Edlund, U., Shockcor, J. P., et al. (2008). Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models. Analytical Chemistry, 80(1), 115-122.
    • (2008) Analytical Chemistry , vol.80 , Issue.1 , pp. 115-122
    • Wiklund, S.1    Johansson, E.2    Sjostrom, L.3    Mellerowicz, E.J.4    Edlund, U.5    Shockcor, J.P.6
  • 62
    • 0000781020 scopus 로고
    • Partial least squares
    • S. Kotz and N. L. Johnson (Eds.), New York: Willey
    • Wold, H. (1985). Partial least squares. In S. Kotz & N. L. Johnson (Eds.), Encyclopedia of statistical sciences (vol. 6, pp. 581-591). New York: Willey.
    • (1985) Encyclopedia of Statistical Sciences , vol.6 , pp. 581-591
    • Wold, H.1
  • 65
    • 79952155958 scopus 로고    scopus 로고
    • Comparison of metabolic profiling of cyanidin-3-O-galactoside and extracts from blueberry in aged mice
    • Yang, H., Pang, W., Lu, H., Cheng, D., Yan, X., Cheng, Y., et al. (2011). Comparison of metabolic profiling of cyanidin-3-O-galactoside and extracts from blueberry in aged mice. Journal of Agricultural and Food Chemistry, 59(5), 2069-2076.
    • (2011) Journal of Agricultural and Food Chemistry , vol.59 , Issue.5 , pp. 2069-2076
    • Yang, H.1    Pang, W.2    Lu, H.3    Cheng, D.4    Yan, X.5    Cheng, Y.6
  • 66
    • 33748316468 scopus 로고    scopus 로고
    • Metabonomics study of intestinal fistulas based on ultraperformance liquid chromatography coupled with Q-TOF mass spectrometry (UPLC/Q-TOF MS)
    • Yin, P., Zhao, X., Li, Q., Wang, J., Li, J., & Xu, G. (2006). Metabonomics study of intestinal fistulas based on ultraperformance liquid chromatography coupled with Q-TOF mass spectrometry (UPLC/Q-TOF MS). Journal of Proteome Research, 5(9), 2135-2143.
    • (2006) Journal of Proteome Research , vol.5 , Issue.9 , pp. 2135-2143
    • Yin, P.1    Zhao, X.2    Li, Q.3    Wang, J.4    Li, J.5    Xu, G.6
  • 67
    • 63649128102 scopus 로고    scopus 로고
    • Development of a robust and repeatable UPLC-MS method for the long-term metabolomic study of human serum
    • Zelena, E., Dunn, W. B., Broadhurst, D., Francis-McIntyre, S., Carroll, K. M., Begley, P., et al. (2009). Development of a robust and repeatable UPLC-MS method for the long-term metabolomic study of human serum. Analytical Chemistry, 81(4), 1357-1364.
    • (2009) Analytical Chemistry , vol.81 , Issue.4 , pp. 1357-1364
    • Zelena, E.1    Dunn, W.B.2    Broadhurst, D.3    Francis-McIntyre, S.4    Carroll, K.M.5    Begley, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.