메뉴 건너뛰기




Volumn 267, Issue 1, 2015, Pages 178-196

Human KIR repertoires: Shaped by genetic diversity and evolution

Author keywords

KIR; NK cells; NKG2A; Primates; Repertoire

Indexed keywords

KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; LEUKOCYTE ANTIGEN; HLA ANTIGEN CLASS 1;

EID: 84939543853     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/imr.12316     Document Type: Article
Times cited : (93)

References (134)
  • 1
    • 0025300414 scopus 로고
    • In search of the 'missing self': MHC molecules and NK cell recognition
    • Ljunggren HG, Karre K. In search of the 'missing self': MHC molecules and NK cell recognition. Immunol Today 1990;11:237-244.
    • (1990) Immunol Today , vol.11 , pp. 237-244
    • Ljunggren, H.G.1    Karre, K.2
  • 2
    • 84901295133 scopus 로고    scopus 로고
    • Deconstructing the peptide-MHC specificity of T cell recognition
    • Birnbaum ME, et al. Deconstructing the peptide-MHC specificity of T cell recognition. Cell 2014;157:1073-1087.
    • (2014) Cell , vol.157 , pp. 1073-1087
    • Birnbaum, M.E.1
  • 3
    • 0035056004 scopus 로고    scopus 로고
    • Regulation of the natural killer cell receptor repertoire
    • Raulet DH, Vance RE, McMahon CW. Regulation of the natural killer cell receptor repertoire. Annu Rev Immunol 2001;19:291-330.
    • (2001) Annu Rev Immunol , vol.19 , pp. 291-330
    • Raulet, D.H.1    Vance, R.E.2    McMahon, C.W.3
  • 4
    • 0002225186 scopus 로고
    • Modification of Jerne's theory of antibody production using the concept of clonal selection
    • Burnet FM. Modification of Jerne's theory of antibody production using the concept of clonal selection. Aust J Sci 1957;20:67-69.
    • (1957) Aust J Sci , vol.20 , pp. 67-69
    • Burnet, F.M.1
  • 5
    • 0016762220 scopus 로고
    • "Natural" killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype
    • Kiessling R, Klein E, Wigzell H. "Natural" killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype. Eur J Immunol 1975;5:112-117.
    • (1975) Eur J Immunol , vol.5 , pp. 112-117
    • Kiessling, R.1    Klein, E.2    Wigzell, H.3
  • 6
    • 0026550049 scopus 로고
    • Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans
    • Ciccone E, et al. Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition: definition of five distinct NK-determined allospecificities in humans. J Exp Med 1992;175:709-718.
    • (1992) J Exp Med , vol.175 , pp. 709-718
    • Ciccone, E.1
  • 7
    • 0028283541 scopus 로고
    • Ly-49 multigene family expressed by IL-2-activated NK cells
    • Smith HR, Karlhofer FM, Yokoyama WM. Ly-49 multigene family expressed by IL-2-activated NK cells. J Immunol 1994;153:1068-1079.
    • (1994) J Immunol , vol.153 , pp. 1068-1079
    • Smith, H.R.1    Karlhofer, F.M.2    Yokoyama, W.M.3
  • 8
    • 0028029464 scopus 로고
    • Expression of different members of the Ly-49 gene family defines distinct natural killer cell subsets and cell adhesion properties
    • Brennan J, Mager D, Jefferies W, Takei F. Expression of different members of the Ly-49 gene family defines distinct natural killer cell subsets and cell adhesion properties. J Exp Med 1994;180:2287-2295.
    • (1994) J Exp Med , vol.180 , pp. 2287-2295
    • Brennan, J.1    Mager, D.2    Jefferies, W.3    Takei, F.4
  • 9
    • 84856630729 scopus 로고    scopus 로고
    • Human-specific evolution of killer cell immunoglobulin-like receptor recognition of major histocompatibility complex class I molecules
    • Parham P, Norman PJ, Abi-Rached L, Guethlein LA. Human-specific evolution of killer cell immunoglobulin-like receptor recognition of major histocompatibility complex class I molecules. Philos Trans R Soc Lond B Biol Sci 2012;367:800-811.
    • (2012) Philos Trans R Soc Lond B Biol Sci , vol.367 , pp. 800-811
    • Parham, P.1    Norman, P.J.2    Abi-Rached, L.3    Guethlein, L.A.4
  • 10
    • 0031406606 scopus 로고    scopus 로고
    • Human diversity in killer cell inhibitory receptor genes
    • Uhrberg M, et al. Human diversity in killer cell inhibitory receptor genes. Immunity 1997;7:753-763.
    • (1997) Immunity , vol.7 , pp. 753-763
    • Uhrberg, M.1
  • 11
    • 78649698599 scopus 로고    scopus 로고
    • Human-specific evolution and adaptation led to major qualitative differences in the variable receptors of human and chimpanzee natural killer cells
    • Abi-Rached L, Moesta AK, Rajalingam R, Guethlein LA, Parham P. Human-specific evolution and adaptation led to major qualitative differences in the variable receptors of human and chimpanzee natural killer cells. PLoS Genet 2010;6:e1001192.
    • (2010) PLoS Genet , vol.6 , pp. e1001192
    • Abi-Rached, L.1    Moesta, A.K.2    Rajalingam, R.3    Guethlein, L.A.4    Parham, P.5
  • 12
    • 0031406018 scopus 로고    scopus 로고
    • Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors
    • Valiante NM, et al. Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors. Immunity 1997;7:739-751.
    • (1997) Immunity , vol.7 , pp. 739-751
    • Valiante, N.M.1
  • 13
    • 0036476017 scopus 로고    scopus 로고
    • KIR expression shapes cytotoxic repertoires: a developmental program of survival
    • Young NT, Uhrberg M. KIR expression shapes cytotoxic repertoires: a developmental program of survival. Trends Immunol 2002;23:71-75.
    • (2002) Trends Immunol , vol.23 , pp. 71-75
    • Young, N.T.1    Uhrberg, M.2
  • 14
    • 27144509642 scopus 로고    scopus 로고
    • Epigenetic control of highly homologous killer Ig-like receptor gene alleles
    • Chan HW, Miller JS, Moore MB, Lutz CT. Epigenetic control of highly homologous killer Ig-like receptor gene alleles. J Immunol 2005;175:5966-5974.
    • (2005) J Immunol , vol.175 , pp. 5966-5974
    • Chan, H.W.1    Miller, J.S.2    Moore, M.B.3    Lutz, C.T.4
  • 15
    • 40449117475 scopus 로고    scopus 로고
    • Lineage-specific transition of histone signatures in the killer cell Ig-like receptor locus from hematopoietic progenitor to NK cells
    • Santourlidis S, Graffmann N, Christ J, Uhrberg M. Lineage-specific transition of histone signatures in the killer cell Ig-like receptor locus from hematopoietic progenitor to NK cells. J Immunol 2008;180:418-425.
    • (2008) J Immunol , vol.180 , pp. 418-425
    • Santourlidis, S.1    Graffmann, N.2    Christ, J.3    Uhrberg, M.4
  • 16
    • 0037108489 scopus 로고    scopus 로고
    • Crucial role of DNA methylation in determination of clonally distributed killer cell Ig-like receptor expression patterns in NK cells
    • Santourlidis S, et al. Crucial role of DNA methylation in determination of clonally distributed killer cell Ig-like receptor expression patterns in NK cells. J Immunol 2002;169:4253-4261.
    • (2002) J Immunol , vol.169 , pp. 4253-4261
    • Santourlidis, S.1
  • 17
    • 34247625129 scopus 로고    scopus 로고
    • Identification of bidirectional promoters in the human KIR genes
    • Davies GE, et al. Identification of bidirectional promoters in the human KIR genes. Genes Immun 2007;8:245-253.
    • (2007) Genes Immun , vol.8 , pp. 245-253
    • Davies, G.E.1
  • 18
    • 33750707891 scopus 로고    scopus 로고
    • Regulation of class I major histocompatibility complex receptor expression in natural killer cells: one promoter is not enough!
    • Pascal V, Stulberg MJ, Anderson SK. Regulation of class I major histocompatibility complex receptor expression in natural killer cells: one promoter is not enough!. Immunol Rev 2006;214:9-21.
    • (2006) Immunol Rev , vol.214 , pp. 9-21
    • Pascal, V.1    Stulberg, M.J.2    Anderson, S.K.3
  • 19
    • 77956925786 scopus 로고    scopus 로고
    • Cutting edge: KIR antisense transcripts are processed into a 28-base PIWI-like RNA in human NK cells
    • Cichocki F, Lenvik T, Sharma N, Yun G, Anderson SK, Miller JS. Cutting edge: KIR antisense transcripts are processed into a 28-base PIWI-like RNA in human NK cells. J Immunol 2010;185:2009-2012.
    • (2010) J Immunol , vol.185 , pp. 2009-2012
    • Cichocki, F.1    Lenvik, T.2    Sharma, N.3    Yun, G.4    Anderson, S.K.5    Miller, J.S.6
  • 20
    • 15444369238 scopus 로고    scopus 로고
    • Three structurally and functionally divergent kinds of promoters regulate expression of clonally distributed killer cell Ig-like receptors (KIR), of KIR2DL4, and of KIR3DL3
    • Trompeter HI, et al. Three structurally and functionally divergent kinds of promoters regulate expression of clonally distributed killer cell Ig-like receptors (KIR), of KIR2DL4, and of KIR3DL3. J Immunol 2005;174:4135-4143.
    • (2005) J Immunol , vol.174 , pp. 4135-4143
    • Trompeter, H.I.1
  • 21
    • 10644226981 scopus 로고    scopus 로고
    • Shaping the human NK cell repertoire: an epigenetic glance at KIR gene regulation
    • Uhrberg M. Shaping the human NK cell repertoire: an epigenetic glance at KIR gene regulation. Mol Immunol 2005;42:471-475.
    • (2005) Mol Immunol , vol.42 , pp. 471-475
    • Uhrberg, M.1
  • 22
    • 84868342527 scopus 로고    scopus 로고
    • Allele-level haplotype frequencies and pairwise linkage disequilibrium for 14 KIR loci in 506 European-American individuals
    • Vierra-Green C, et al. Allele-level haplotype frequencies and pairwise linkage disequilibrium for 14 KIR loci in 506 European-American individuals. PLoS ONE 2012;7:e47491.
    • (2012) PLoS ONE , vol.7 , pp. e47491
    • Vierra-Green, C.1
  • 23
    • 0036326792 scopus 로고    scopus 로고
    • Definition of gene content for nine common group B haplotypes of the Caucasoid population: KIR haplotypes contain between seven and eleven KIR genes
    • Uhrberg M, Parham P, Wernet P. Definition of gene content for nine common group B haplotypes of the Caucasoid population: KIR haplotypes contain between seven and eleven KIR genes. Immunogenetics 2002;54:221-229.
    • (2002) Immunogenetics , vol.54 , pp. 221-229
    • Uhrberg, M.1    Parham, P.2    Wernet, P.3
  • 24
    • 0036215134 scopus 로고    scopus 로고
    • KIR: diverse, rapidly evolving receptors of innate and adaptive immunity
    • Vilches C, Parham P. KIR: diverse, rapidly evolving receptors of innate and adaptive immunity. Annu Rev Immunol 2002;20:217-251.
    • (2002) Annu Rev Immunol , vol.20 , pp. 217-251
    • Vilches, C.1    Parham, P.2
  • 25
    • 70449732607 scopus 로고    scopus 로고
    • KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C
    • Graef T, et al. KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C. J Exp Med 2009;206:2557-2572.
    • (2009) J Exp Med , vol.206 , pp. 2557-2572
    • Graef, T.1
  • 26
    • 84885156420 scopus 로고    scopus 로고
    • HLA-F and MHC class I open conformers are ligands for NK cell Ig-like receptors
    • Goodridge JP, Burian A, Lee N, Geraghty DE. HLA-F and MHC class I open conformers are ligands for NK cell Ig-like receptors. J Immunol 2013;191:3553-3562.
    • (2013) J Immunol , vol.191 , pp. 3553-3562
    • Goodridge, J.P.1    Burian, A.2    Lee, N.3    Geraghty, D.E.4
  • 27
    • 1842858906 scopus 로고    scopus 로고
    • A common KIR2DS4 deletion variant in the human that predicts a soluble KIR molecule analogous to the KIR1D molecule observed in the rhesus monkey
    • Maxwell LD, Wallace A, Middleton D, Curran MD. A common KIR2DS4 deletion variant in the human that predicts a soluble KIR molecule analogous to the KIR1D molecule observed in the rhesus monkey. Tissue Antigens 2002;60:254-258.
    • (2002) Tissue Antigens , vol.60 , pp. 254-258
    • Maxwell, L.D.1    Wallace, A.2    Middleton, D.3    Curran, M.D.4
  • 28
    • 0042090493 scopus 로고    scopus 로고
    • KIR2DL4 (CD158d) genotype influences expression and function in NK cells
    • Goodridge JP, Witt CS, Christiansen FT, Warren HS. KIR2DL4 (CD158d) genotype influences expression and function in NK cells. J Immunol 2003;171:1768-1774.
    • (2003) J Immunol , vol.171 , pp. 1768-1774
    • Goodridge, J.P.1    Witt, C.S.2    Christiansen, F.T.3    Warren, H.S.4
  • 29
    • 0033526056 scopus 로고    scopus 로고
    • A human histocompatibility leukocyte antigen (HLA)-G-specific receptor expressed on all natural killer cells
    • Rajagopalan S, Long EO. A human histocompatibility leukocyte antigen (HLA)-G-specific receptor expressed on all natural killer cells. J Exp Med 1999;189:1093-1100.
    • (1999) J Exp Med , vol.189 , pp. 1093-1100
    • Rajagopalan, S.1    Long, E.O.2
  • 30
    • 84892722062 scopus 로고    scopus 로고
    • Killer Ig-like receptor 2DL4 does not mediate NK cell IFN-gamma responses to soluble HLA-G preparations
    • Le Page ME, Goodridge JP, John E, Christiansen FT, Witt CS. Killer Ig-like receptor 2DL4 does not mediate NK cell IFN-gamma responses to soluble HLA-G preparations. J Immunol 2014;192:732-740.
    • (2014) J Immunol , vol.192 , pp. 732-740
    • Le Page, M.E.1    Goodridge, J.P.2    John, E.3    Christiansen, F.T.4    Witt, C.S.5
  • 31
    • 84927918837 scopus 로고    scopus 로고
    • The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4
    • Moradi S, et al. The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4. J Biol Chem 2015;290:10460-10471.
    • (2015) J Biol Chem , vol.290 , pp. 10460-10471
    • Moradi, S.1
  • 32
    • 33645070552 scopus 로고    scopus 로고
    • Roles for HLA and KIR polymorphisms in natural killer cell repertoire selection and modulation of effector function
    • Yawata M, Yawata N, Draghi M, Little AM, Partheniou F, Parham P. Roles for HLA and KIR polymorphisms in natural killer cell repertoire selection and modulation of effector function. J Exp Med 2006;203:633-645.
    • (2006) J Exp Med , vol.203 , pp. 633-645
    • Yawata, M.1    Yawata, N.2    Draghi, M.3    Little, A.M.4    Partheniou, F.5    Parham, P.6
  • 33
    • 67651068734 scopus 로고    scopus 로고
    • KIR acquisition probabilities are independent of self-HLA class I ligands and increase with cellular KIR expression
    • Andersson S, Fauriat C, Malmberg JA, Ljunggren HG, Malmberg KJ. KIR acquisition probabilities are independent of self-HLA class I ligands and increase with cellular KIR expression. Blood 2009;114:95-104.
    • (2009) Blood , vol.114 , pp. 95-104
    • Andersson, S.1    Fauriat, C.2    Malmberg, J.A.3    Ljunggren, H.G.4    Malmberg, K.J.5
  • 34
    • 78650989096 scopus 로고    scopus 로고
    • Analyses of HLA-C-specific KIR repertoires in donors with group A and B haplotypes suggest a ligand-instructed model of NK cell receptor acquisition
    • Schonberg K, Sribar M, Enczmann J, Fischer JC, Uhrberg M. Analyses of HLA-C-specific KIR repertoires in donors with group A and B haplotypes suggest a ligand-instructed model of NK cell receptor acquisition. Blood 2011;117:98-107.
    • (2011) Blood , vol.117 , pp. 98-107
    • Schonberg, K.1    Sribar, M.2    Enczmann, J.3    Fischer, J.C.4    Uhrberg, M.5
  • 36
    • 0032546001 scopus 로고    scopus 로고
    • HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C
    • Braud VM, et al. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 1998;391:795-799.
    • (1998) Nature , vol.391 , pp. 795-799
    • Braud, V.M.1
  • 37
    • 0032473478 scopus 로고    scopus 로고
    • Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis
    • Borrego F, Ulbrecht M, Weiss EH, Coligan JE, Brooks AG. Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis. J Exp Med 1998;187:813-818.
    • (1998) J Exp Med , vol.187 , pp. 813-818
    • Borrego, F.1    Ulbrecht, M.2    Weiss, E.H.3    Coligan, J.E.4    Brooks, A.G.5
  • 38
    • 0032524965 scopus 로고    scopus 로고
    • HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences
    • Lee N, Goodlett DR, Ishitani A, Marquardt H, Geraghty DE. HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences. J Immunol 1998;160:4951-4960.
    • (1998) J Immunol , vol.160 , pp. 4951-4960
    • Lee, N.1    Goodlett, D.R.2    Ishitani, A.3    Marquardt, H.4    Geraghty, D.E.5
  • 39
    • 0030768392 scopus 로고    scopus 로고
    • A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules
    • Cosman D, et al. A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules. Immunity 1997;7:273-282.
    • (1997) Immunity , vol.7 , pp. 273-282
    • Cosman, D.1
  • 40
    • 0030819308 scopus 로고    scopus 로고
    • A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells
    • Colonna M, et al. A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J Exp Med 1997;186:1809-1818.
    • (1997) J Exp Med , vol.186 , pp. 1809-1818
    • Colonna, M.1
  • 41
    • 0031214126 scopus 로고    scopus 로고
    • A new human gene complex encoding the killer cell inhibitory receptors and related monocyte/macrophage receptors
    • Wagtmann N, Rojo S, Eichler E, Mohrenweiser H, Long EO. A new human gene complex encoding the killer cell inhibitory receptors and related monocyte/macrophage receptors. Curr Biol 1997;7:615-618.
    • (1997) Curr Biol , vol.7 , pp. 615-618
    • Wagtmann, N.1    Rojo, S.2    Eichler, E.3    Mohrenweiser, H.4    Long, E.O.5
  • 42
    • 0032950689 scopus 로고    scopus 로고
    • + NK cell clones
    • + NK cell clones. Int Immunol 1999;11:29-35.
    • (1999) Int Immunol , vol.11 , pp. 29-35
    • Vitale, M.1
  • 43
    • 55249092534 scopus 로고    scopus 로고
    • MHC class I-specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response
    • Yawata M, Yawata N, Draghi M, Partheniou F, Little AM, Parham P. MHC class I-specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response. Blood 2008;112:2369-2380.
    • (2008) Blood , vol.112 , pp. 2369-2380
    • Yawata, M.1    Yawata, N.2    Draghi, M.3    Partheniou, F.4    Little, A.M.5    Parham, P.6
  • 44
    • 79251631976 scopus 로고    scopus 로고
    • Structure/function of human killer cell immunoglobulin-like receptors: lessons from polymorphisms, evolution, crystal structures and mutations
    • Campbell KS, Purdy AK. Structure/function of human killer cell immunoglobulin-like receptors: lessons from polymorphisms, evolution, crystal structures and mutations. Immunology 2011;132:315-325.
    • (2011) Immunology , vol.132 , pp. 315-325
    • Campbell, K.S.1    Purdy, A.K.2
  • 45
    • 73949107886 scopus 로고    scopus 로고
    • Significant functional heterogeneity among KIR2DL1 alleles and a pivotal role of arginine 245
    • Bari R, et al. Significant functional heterogeneity among KIR2DL1 alleles and a pivotal role of arginine 245. Blood 2009;114:5182-5190.
    • (2009) Blood , vol.114 , pp. 5182-5190
    • Bari, R.1
  • 46
    • 84886045832 scopus 로고    scopus 로고
    • Large spectrum of HLA-C recognition by killer Ig-like receptor (KIR)2DL2 and KIR2DL3 and restricted C1 SPECIFICITY of KIR2DS2: dominant impact of KIR2DL2/KIR2DS2 on KIR2D NK cell repertoire formation
    • David G, et al. Large spectrum of HLA-C recognition by killer Ig-like receptor (KIR)2DL2 and KIR2DL3 and restricted C1 SPECIFICITY of KIR2DS2: dominant impact of KIR2DL2/KIR2DS2 on KIR2D NK cell repertoire formation. J Immunol 2013;191:4778-4788.
    • (2013) J Immunol , vol.191 , pp. 4778-4788
    • David, G.1
  • 47
    • 84864148132 scopus 로고    scopus 로고
    • Mutation at positively selected positions in the binding site for HLA-C shows that KIR2DL1 is a more refined but less adaptable NK cell receptor than KIR2DL3
    • Hilton HG, et al. Mutation at positively selected positions in the binding site for HLA-C shows that KIR2DL1 is a more refined but less adaptable NK cell receptor than KIR2DL3. J Immunol 2012;189:1418-1430.
    • (2012) J Immunol , vol.189 , pp. 1418-1430
    • Hilton, H.G.1
  • 48
    • 84907709993 scopus 로고    scopus 로고
    • KIR ligand C2 is associated with increased susceptibility to childhood ALL and confers an elevated risk for late relapse
    • Babor F, et al. KIR ligand C2 is associated with increased susceptibility to childhood ALL and confers an elevated risk for late relapse. Blood 2014;124:2248-2251.
    • (2014) Blood , vol.124 , pp. 2248-2251
    • Babor, F.1
  • 49
    • 0029797865 scopus 로고    scopus 로고
    • Major histocompatibility complex class I-dependent skewing of the natural killer cell Ly49 receptor repertoire
    • Held W, Dorfman JR, Wu MF, Raulet DH. Major histocompatibility complex class I-dependent skewing of the natural killer cell Ly49 receptor repertoire. Eur J Immunol 1996;26:2286-2292.
    • (1996) Eur J Immunol , vol.26 , pp. 2286-2292
    • Held, W.1    Dorfman, J.R.2    Wu, M.F.3    Raulet, D.H.4
  • 50
    • 0031110365 scopus 로고    scopus 로고
    • Altered expression of Ly49 inhibitory receptors on natural killer cells from MHC class I-deficient mice
    • Salcedo M, et al. Altered expression of Ly49 inhibitory receptors on natural killer cells from MHC class I-deficient mice. J Immunol 1997;158:3174-3180.
    • (1997) J Immunol , vol.158 , pp. 3174-3180
    • Salcedo, M.1
  • 51
    • 18844365992 scopus 로고    scopus 로고
    • A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules
    • Fernandez NC, Treiner E, Vance RE, Jamieson AM, Lemieux S, Raulet DH. A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules. Blood 2005;105:4416-4423.
    • (2005) Blood , vol.105 , pp. 4416-4423
    • Fernandez, N.C.1    Treiner, E.2    Vance, R.E.3    Jamieson, A.M.4    Lemieux, S.5    Raulet, D.H.6
  • 52
    • 23644458333 scopus 로고    scopus 로고
    • Licensing of natural killer cells by host major histocompatibility complex class I molecules
    • Kim S, et al. Licensing of natural killer cells by host major histocompatibility complex class I molecules. Nature 2005;436:709-713.
    • (2005) Nature , vol.436 , pp. 709-713
    • Kim, S.1
  • 53
    • 33747101972 scopus 로고    scopus 로고
    • Human NK cell education by inhibitory receptors for MHC class I
    • Anfossi N, et al. Human NK cell education by inhibitory receptors for MHC class I. Immunity 2006;25:331-342.
    • (2006) Immunity , vol.25 , pp. 331-342
    • Anfossi, N.1
  • 54
    • 79955963944 scopus 로고    scopus 로고
    • Neonatal NK-cell repertoires are functionally, but not structurally, biased toward recognition of self HLA class I
    • Schonberg K, Fischer JC, Kogler G, Uhrberg M. Neonatal NK-cell repertoires are functionally, but not structurally, biased toward recognition of self HLA class I. Blood 2011;117:5152-5156.
    • (2011) Blood , vol.117 , pp. 5152-5156
    • Schonberg, K.1    Fischer, J.C.2    Kogler, G.3    Uhrberg, M.4
  • 55
    • 78651492046 scopus 로고    scopus 로고
    • Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus
    • Bjorkstrom NK, et al. Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus. J Exp Med 2010;208:13-21.
    • (2010) J Exp Med , vol.208 , pp. 13-21
    • Bjorkstrom, N.K.1
  • 56
    • 9444273448 scopus 로고    scopus 로고
    • Imprint of human cytomegalovirus infection on the NK cell receptor repertoire
    • Guma M, Angulo A, Vilches C, Gomez-Lozano N, Malats N, Lopez-Botet M. Imprint of human cytomegalovirus infection on the NK cell receptor repertoire. Blood 2004;104:3664-3671.
    • (2004) Blood , vol.104 , pp. 3664-3671
    • Guma, M.1    Angulo, A.2    Vilches, C.3    Gomez-Lozano, N.4    Malats, N.5    Lopez-Botet, M.6
  • 57
    • 84897965082 scopus 로고    scopus 로고
    • + NK-cell subset on the edge of innate and adaptive immunity to human cytomegalovirus infection
    • + NK-cell subset on the edge of innate and adaptive immunity to human cytomegalovirus infection. Semin Immunol 2014;26:145-151.
    • (2014) Semin Immunol , vol.26 , pp. 145-151
    • Lopez-Botet, M.1    Muntasell, A.2    Vilches, C.3
  • 58
    • 84856055597 scopus 로고    scopus 로고
    • + NK cells expressing self-specific KIRs in chronic hepatitis patients
    • + NK cells expressing self-specific KIRs in chronic hepatitis patients. Eur J Immunol 2012;42:447-457.
    • (2012) Eur J Immunol , vol.42 , pp. 447-457
    • Beziat, V.1
  • 59
    • 33745211470 scopus 로고    scopus 로고
    • Human cytomegalovirus infection is associated with increased proportions of NK cells that express the CD94/NKG2C receptor in aviremic HIV-1-positive patients
    • Guma M, et al. Human cytomegalovirus infection is associated with increased proportions of NK cells that express the CD94/NKG2C receptor in aviremic HIV-1-positive patients. J Infect Dis 2006;194:38-41.
    • (2006) J Infect Dis , vol.194 , pp. 38-41
    • Guma, M.1
  • 60
    • 84863338121 scopus 로고    scopus 로고
    • + natural killer cells with potent function
    • + natural killer cells with potent function. Blood 2012;119:2665-2674.
    • (2012) Blood , vol.119 , pp. 2665-2674
    • Foley, B.1
  • 61
    • 84876878182 scopus 로고    scopus 로고
    • NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs
    • Beziat V, et al. NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs. Blood 2013;121:2678-2688.
    • (2013) Blood , vol.121 , pp. 2678-2688
    • Beziat, V.1
  • 63
    • 0037123607 scopus 로고    scopus 로고
    • Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors
    • Arase H, Mocarski ES, Campbell AE, Hill AB, Lanier LL. Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors. Science 2002;296:1323-1326.
    • (2002) Science , vol.296 , pp. 1323-1326
    • Arase, H.1    Mocarski, E.S.2    Campbell, A.E.3    Hill, A.B.4    Lanier, L.L.5
  • 64
    • 0037172968 scopus 로고    scopus 로고
    • Recognition of a virus-encoded ligand by a natural killer cell activation receptor
    • Smith HR, et al. Recognition of a virus-encoded ligand by a natural killer cell activation receptor. Proc Natl Acad Sci USA 2002;99:8826-8831.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8826-8831
    • Smith, H.R.1
  • 65
    • 84924955835 scopus 로고    scopus 로고
    • Epigenetic modification and antibody-dependent expansion of memory-like NK cells in human cytomegalovirus-infected individuals
    • Lee J, et al. Epigenetic modification and antibody-dependent expansion of memory-like NK cells in human cytomegalovirus-infected individuals. Immunity 2015;42:431-442.
    • (2015) Immunity , vol.42 , pp. 431-442
    • Lee, J.1
  • 66
    • 42449102990 scopus 로고    scopus 로고
    • Up on the tightrope: natural killer cell activation and inhibition
    • Lanier LL. Up on the tightrope: natural killer cell activation and inhibition. Nat Immunol 2008;9:495-502.
    • (2008) Nat Immunol , vol.9 , pp. 495-502
    • Lanier, L.L.1
  • 67
    • 0037654923 scopus 로고    scopus 로고
    • Variation within the human killer cell immunoglobulin-like receptor (KIR) gene family
    • Yawata M, Yawata N, Abi-Rached L, Parham P. Variation within the human killer cell immunoglobulin-like receptor (KIR) gene family. Crit Rev Immunol 2002;22:463-482.
    • (2002) Crit Rev Immunol , vol.22 , pp. 463-482
    • Yawata, M.1    Yawata, N.2    Abi-Rached, L.3    Parham, P.4
  • 68
    • 0036839601 scopus 로고    scopus 로고
    • Killer Ig-like receptor haplotype analysis by gene content: evidence for genomic diversity with a minimum of six basic framework haplotypes, each with multiple subsets
    • Hsu KC, Liu XR, Selvakumar A, Mickelson E, O'Reilly RJ, Dupont B. Killer Ig-like receptor haplotype analysis by gene content: evidence for genomic diversity with a minimum of six basic framework haplotypes, each with multiple subsets. J Immunol 2002;169:5118-5129.
    • (2002) J Immunol , vol.169 , pp. 5118-5129
    • Hsu, K.C.1    Liu, X.R.2    Selvakumar, A.3    Mickelson, E.4    O'Reilly, R.J.5    Dupont, B.6
  • 69
    • 0034712841 scopus 로고    scopus 로고
    • Plasticity in the organization and sequences of human KIR/ILT gene families
    • Wilson MJ, et al. Plasticity in the organization and sequences of human KIR/ILT gene families. Proc Natl Acad Sci USA 2000;97:4778-4783.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 4778-4783
    • Wilson, M.J.1
  • 70
    • 12344318985 scopus 로고    scopus 로고
    • The KIR gene family: life in the fast lane of evolution
    • Uhrberg M. The KIR gene family: life in the fast lane of evolution. Eur J Immunol 2005;35:10-15.
    • (2005) Eur J Immunol , vol.35 , pp. 10-15
    • Uhrberg, M.1
  • 71
    • 61849136780 scopus 로고    scopus 로고
    • Dramatically reduced surface expression of NK cell receptor KIR2DS3 is attributed to multiple residues throughout the molecule
    • VandenBussche CJ, Mulrooney TJ, Frazier WR, Dakshanamurthy S, Hurley CK. Dramatically reduced surface expression of NK cell receptor KIR2DS3 is attributed to multiple residues throughout the molecule. Genes Immun 2009;10:162-173.
    • (2009) Genes Immun , vol.10 , pp. 162-173
    • VandenBussche, C.J.1    Mulrooney, T.J.2    Frazier, W.R.3    Dakshanamurthy, S.4    Hurley, C.K.5
  • 72
    • 31844441736 scopus 로고    scopus 로고
    • Molecular characterization of KIR3DL3
    • Trundley AE, et al. Molecular characterization of KIR3DL3. Immunogenetics 2006;57:904-916.
    • (2006) Immunogenetics , vol.57 , pp. 904-916
    • Trundley, A.E.1
  • 73
    • 0034541179 scopus 로고    scopus 로고
    • Gene structure and promoter variation of expressed and nonexpressed variants of the KIR2DL5 gene
    • Vilches C, Gardiner CM, Parham P. Gene structure and promoter variation of expressed and nonexpressed variants of the KIR2DL5 gene. J Immunol 2000;165:6416-6421.
    • (2000) J Immunol , vol.165 , pp. 6416-6421
    • Vilches, C.1    Gardiner, C.M.2    Parham, P.3
  • 74
    • 84886419332 scopus 로고    scopus 로고
    • Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry
    • Horowitz A, et al. Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry. Sci Transl Med 2013;5:208ra145.
    • (2013) Sci Transl Med , vol.5
    • Horowitz, A.1
  • 75
    • 84893863917 scopus 로고    scopus 로고
    • Of snowflakes and natural killer cell subsets
    • Lanier LL. Of snowflakes and natural killer cell subsets. Nat Biotechnol 2014;32:140-142.
    • (2014) Nat Biotechnol , vol.32 , pp. 140-142
    • Lanier, L.L.1
  • 76
    • 0035059950 scopus 로고    scopus 로고
    • Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis
    • Moretta A, et al. Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu Rev Immunol 2001;19:197-223.
    • (2001) Annu Rev Immunol , vol.19 , pp. 197-223
    • Moretta, A.1
  • 78
    • 84893833939 scopus 로고    scopus 로고
    • Beyond model antigens: high-dimensional methods for the analysis of antigen-specific T cells
    • Newell EW, Davis MM. Beyond model antigens: high-dimensional methods for the analysis of antigen-specific T cells. Nat Biotechnol 2014;32:149-157.
    • (2014) Nat Biotechnol , vol.32 , pp. 149-157
    • Newell, E.W.1    Davis, M.M.2
  • 79
    • 0034986721 scopus 로고    scopus 로고
    • Genomic diversity of natural killer cell receptor genes in three populations
    • Toneva M, et al. Genomic diversity of natural killer cell receptor genes in three populations. Tissue Antigens 2001;57:358-362.
    • (2001) Tissue Antigens , vol.57 , pp. 358-362
    • Toneva, M.1
  • 80
    • 7244234068 scopus 로고    scopus 로고
    • Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success
    • Hiby SE, et al. Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success. J Exp Med 2004;200:957-965.
    • (2004) J Exp Med , vol.200 , pp. 957-965
    • Hiby, S.E.1
  • 81
    • 84922295428 scopus 로고    scopus 로고
    • The role of the maternal immune system in the regulation of human birthweight
    • Moffett A, Hiby SE, Sharkey AM. The role of the maternal immune system in the regulation of human birthweight. Philos Trans R Soc Lond B Biol Sci 2015;370:20140071.
    • (2015) Philos Trans R Soc Lond B Biol Sci , vol.370 , pp. 20140071
    • Moffett, A.1    Hiby, S.E.2    Sharkey, A.M.3
  • 82
    • 0036719573 scopus 로고    scopus 로고
    • Natural killer cells and pregnancy
    • Moffett-King A. Natural killer cells and pregnancy. Nat Rev Immunol 2002;2:656-663.
    • (2002) Nat Rev Immunol , vol.2 , pp. 656-663
    • Moffett-King, A.1
  • 83
    • 78049433758 scopus 로고    scopus 로고
    • Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2
    • Hiby SE, et al. Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2. J Clin Invest 2010;120:4102-4110.
    • (2010) J Clin Invest , vol.120 , pp. 4102-4110
    • Hiby, S.E.1
  • 84
    • 84921395724 scopus 로고    scopus 로고
    • A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia
    • Nakimuli A, et al. A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia. Proc Natl Acad Sci USA 2015;112:845-850.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. 845-850
    • Nakimuli, A.1
  • 85
    • 84872920040 scopus 로고    scopus 로고
    • Variable NK cell receptors and their MHC class I ligands in immunity, reproduction and human evolution
    • Parham P, Moffett A. Variable NK cell receptors and their MHC class I ligands in immunity, reproduction and human evolution. Nat Rev Immunol 2013;13:133-144.
    • (2013) Nat Rev Immunol , vol.13 , pp. 133-144
    • Parham, P.1    Moffett, A.2
  • 86
    • 3843075120 scopus 로고    scopus 로고
    • HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection
    • Khakoo SI, et al. HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection. Science 2004;305:872-874.
    • (2004) Science , vol.305 , pp. 872-874
    • Khakoo, S.I.1
  • 87
    • 56549090945 scopus 로고    scopus 로고
    • The Yin and Yang of HLA and KIR in human disease
    • Kulkarni S, Martin MP, Carrington M. The Yin and Yang of HLA and KIR in human disease. Semin Immunol 2008;20:343-352.
    • (2008) Semin Immunol , vol.20 , pp. 343-352
    • Kulkarni, S.1    Martin, M.P.2    Carrington, M.3
  • 88
    • 0036699528 scopus 로고    scopus 로고
    • Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS
    • Martin MP, et al. Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS. Nat Genet 2002;31:429-434.
    • (2002) Nat Genet , vol.31 , pp. 429-434
    • Martin, M.P.1
  • 89
    • 84941091243 scopus 로고    scopus 로고
    • Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations
    • Gonzalez-Galarza FF, et al. Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations. Nucleic Acids Res 2015;43:D784-D788.
    • (2015) Nucleic Acids Res , vol.43 , pp. D784-D788
    • Gonzalez-Galarza, F.F.1
  • 90
    • 79961032359 scopus 로고    scopus 로고
    • Diversity of killer cell immunoglobulin-like receptor genes in four ethnic groups in China
    • Yao Y, et al. Diversity of killer cell immunoglobulin-like receptor genes in four ethnic groups in China. Immunogenetics 2011;63:475-483.
    • (2011) Immunogenetics , vol.63 , pp. 475-483
    • Yao, Y.1
  • 91
    • 84862122547 scopus 로고    scopus 로고
    • The role of classical and non-classical HLA class I antigens in human tumors
    • Bukur J, Jasinski S, Seliger B. The role of classical and non-classical HLA class I antigens in human tumors. Semin Cancer Biol 2012;22:350-358.
    • (2012) Semin Cancer Biol , vol.22 , pp. 350-358
    • Bukur, J.1    Jasinski, S.2    Seliger, B.3
  • 92
    • 70350048798 scopus 로고    scopus 로고
    • The genetics of inbreeding depression
    • Charlesworth D, Willis JH. The genetics of inbreeding depression. Nat Rev Genet 2009;10:783-796.
    • (2009) Nat Rev Genet , vol.10 , pp. 783-796
    • Charlesworth, D.1    Willis, J.H.2
  • 93
    • 73249146908 scopus 로고    scopus 로고
    • Co-evolution of KIR2DL3 with HLA-C in a human population retaining minimal essential diversity of KIR and HLA class I ligands
    • Gendzekhadze K, et al. Co-evolution of KIR2DL3 with HLA-C in a human population retaining minimal essential diversity of KIR and HLA class I ligands. Proc Natl Acad Sci USA 2009;106:18692-18697.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 18692-18697
    • Gendzekhadze, K.1
  • 94
    • 40849085292 scopus 로고    scopus 로고
    • The late Pleistocene dispersal of modern humans in the Americas
    • Goebel T, Waters MR, O'Rourke DH. The late Pleistocene dispersal of modern humans in the Americas. Science 2008;319:1497-1502.
    • (2008) Science , vol.319 , pp. 1497-1502
    • Goebel, T.1    Waters, M.R.2    O'Rourke, D.H.3
  • 95
    • 39749181521 scopus 로고    scopus 로고
    • Worldwide human relationships inferred from genome-wide patterns of variation
    • Li JZ, et al. Worldwide human relationships inferred from genome-wide patterns of variation. Science 2008;319:1100-1104.
    • (2008) Science , vol.319 , pp. 1100-1104
    • Li, J.Z.1
  • 96
    • 70349507629 scopus 로고    scopus 로고
    • Out of Africa: modern human origins special feature: explaining worldwide patterns of human genetic variation using a coalescent-based serial founder model of migration outward from Africa
    • DeGiorgio M, Jakobsson M, Rosenberg NA. Out of Africa: modern human origins special feature: explaining worldwide patterns of human genetic variation using a coalescent-based serial founder model of migration outward from Africa. Proc Natl Acad Sci USA 2009;106:16057-16062.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 16057-16062
    • DeGiorgio, M.1    Jakobsson, M.2    Rosenberg, N.A.3
  • 97
    • 73349126136 scopus 로고    scopus 로고
    • A novel system of polymorphic and diverse NK cell receptors in primates
    • Averdam A, et al. A novel system of polymorphic and diverse NK cell receptors in primates. PLoS Genet 2009;5:e1000688.
    • (2009) PLoS Genet , vol.5 , pp. e1000688
    • Averdam, A.1
  • 98
    • 79953755778 scopus 로고    scopus 로고
    • A molecular phylogeny of living primates
    • Perelman P, et al. A molecular phylogeny of living primates. PLoS Genet 2011;7:e1001342.
    • (2011) PLoS Genet , vol.7 , pp. e1001342
    • Perelman, P.1
  • 99
    • 0033667771 scopus 로고    scopus 로고
    • Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpanzees and humans
    • Khakoo SI, et al. Rapid evolution of NK cell receptor systems demonstrated by comparison of chimpanzees and humans. Immunity 2000;12:687-698.
    • (2000) Immunity , vol.12 , pp. 687-698
    • Khakoo, S.I.1
  • 100
    • 44849124947 scopus 로고    scopus 로고
    • Synergistic polymorphism at two positions distal to the ligand-binding site makes KIR2DL2 a stronger receptor for HLA-C than KIR2DL3
    • Moesta AK, Norman PJ, Yawata M, Yawata N, Gleimer M, Parham P. Synergistic polymorphism at two positions distal to the ligand-binding site makes KIR2DL2 a stronger receptor for HLA-C than KIR2DL3. J Immunol 2008;180:3969-3979.
    • (2008) J Immunol , vol.180 , pp. 3969-3979
    • Moesta, A.K.1    Norman, P.J.2    Yawata, M.3    Yawata, N.4    Gleimer, M.5    Parham, P.6
  • 101
  • 102
    • 80052150716 scopus 로고    scopus 로고
    • The extreme plasticity of killer cell Ig-like receptor (KIR) haplotypes differentiates rhesus macaques from humans
    • Blokhuis JH, van der Wiel MK, Doxiadis GG, Bontrop RE. The extreme plasticity of killer cell Ig-like receptor (KIR) haplotypes differentiates rhesus macaques from humans. Eur J Immunol 2011;41:2719-2728.
    • (2011) Eur J Immunol , vol.41 , pp. 2719-2728
    • Blokhuis, J.H.1    van der Wiel, M.K.2    Doxiadis, G.G.3    Bontrop, R.E.4
  • 103
    • 84919342738 scopus 로고    scopus 로고
    • Progression to AIDS in SIV-infected rhesus macaques is associated with distinct KIR and MHC class I polymorphisms and NK cell dysfunction
    • Albrecht C, Malzahn D, Brameier M, Hermes M, Ansari AA, Walter L. Progression to AIDS in SIV-infected rhesus macaques is associated with distinct KIR and MHC class I polymorphisms and NK cell dysfunction. Front Immunol 2014;5:600.
    • (2014) Front Immunol , vol.5 , pp. 600
    • Albrecht, C.1    Malzahn, D.2    Brameier, M.3    Hermes, M.4    Ansari, A.A.5    Walter, L.6
  • 104
    • 84878079129 scopus 로고    scopus 로고
    • Expression patterns of killer cell immunoglobulin-like receptors (KIR) of NK-cell and T-cell subsets in Old World monkeys
    • Hermes M, Albrecht C, Schrod A, Brameier M, Walter L. Expression patterns of killer cell immunoglobulin-like receptors (KIR) of NK-cell and T-cell subsets in Old World monkeys. PLoS ONE 2013;8:e64936.
    • (2013) PLoS ONE , vol.8 , pp. e64936
    • Hermes, M.1    Albrecht, C.2    Schrod, A.3    Brameier, M.4    Walter, L.5
  • 105
    • 84867182170 scopus 로고    scopus 로고
    • Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors
    • Jiang W, et al. Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors. Genome Res 2012;22:1845-1854.
    • (2012) Genome Res , vol.22 , pp. 1845-1854
    • Jiang, W.1
  • 106
    • 18244393431 scopus 로고    scopus 로고
    • Natural selection drives recurrent formation of activating killer cell immunoglobulin-like receptor and Ly49 from inhibitory homologues
    • Abi-Rached L, Parham P. Natural selection drives recurrent formation of activating killer cell immunoglobulin-like receptor and Ly49 from inhibitory homologues. J Exp Med 2005;201:1319-1332.
    • (2005) J Exp Med , vol.201 , pp. 1319-1332
    • Abi-Rached, L.1    Parham, P.2
  • 107
    • 0031471529 scopus 로고    scopus 로고
    • Role of amino acid position 70 in the binding affinity of p50.1 and p58.1 receptors for HLA-Cw4 molecules
    • Biassoni R, et al. Role of amino acid position 70 in the binding affinity of p50.1 and p58.1 receptors for HLA-Cw4 molecules. Eur J Immunol 1997;27:3095-3099.
    • (1997) Eur J Immunol , vol.27 , pp. 3095-3099
    • Biassoni, R.1
  • 109
    • 0032564356 scopus 로고    scopus 로고
    • Differential binding to HLA-C of p50-activating and p58-inhibitory natural killer cell receptors
    • Vales-Gomez M, Reyburn HT, Erskine RA, Strominger J. Differential binding to HLA-C of p50-activating and p58-inhibitory natural killer cell receptors. Proc Natl Acad Sci USA 1998;95:14326-14331.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 14326-14331
    • Vales-Gomez, M.1    Reyburn, H.T.2    Erskine, R.A.3    Strominger, J.4
  • 110
    • 0031136751 scopus 로고    scopus 로고
    • A single amino acid in the p58 killer cell inhibitory receptor controls the ability of natural killer cells to discriminate between the two groups of HLA-C allotypes
    • Winter CC, Long EO. A single amino acid in the p58 killer cell inhibitory receptor controls the ability of natural killer cells to discriminate between the two groups of HLA-C allotypes. J Immunol 1997;158:4026-4028.
    • (1997) J Immunol , vol.158 , pp. 4026-4028
    • Winter, C.C.1    Long, E.O.2
  • 111
    • 0025677333 scopus 로고
    • + natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition
    • + natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognition. J Exp Med 1990;172:1589-1598.
    • (1990) J Exp Med , vol.172 , pp. 1589-1598
    • Moretta, A.1
  • 112
    • 0031202039 scopus 로고    scopus 로고
    • CD94/NKG2 is the predominant inhibitory receptor involved in recognition of HLA-G by decidual and peripheral blood NK cells
    • Soderstrom K, Corliss B, Lanier LL, Phillips JH. CD94/NKG2 is the predominant inhibitory receptor involved in recognition of HLA-G by decidual and peripheral blood NK cells. J Immunol 1997;159:1072-1075.
    • (1997) J Immunol , vol.159 , pp. 1072-1075
    • Soderstrom, K.1    Corliss, B.2    Lanier, L.L.3    Phillips, J.H.4
  • 113
    • 84904392263 scopus 로고    scopus 로고
    • Tracing dynamic expansion of human NK-cell subsets by high-resolution analysis of KIR repertoires and cellular differentiation
    • Beziat V, et al. Tracing dynamic expansion of human NK-cell subsets by high-resolution analysis of KIR repertoires and cellular differentiation. Eur J Immunol 2014;44:2192-2196.
    • (2014) Eur J Immunol , vol.44 , pp. 2192-2196
    • Beziat, V.1
  • 114
    • 84887494494 scopus 로고    scopus 로고
    • Genome-wide siRNA screen reveals a new cellular partner of NK cell receptor KIR2DL4: heparan sulfate directly modulates KIR2DL4-mediated responses
    • Brusilovsky M, et al. Genome-wide siRNA screen reveals a new cellular partner of NK cell receptor KIR2DL4: heparan sulfate directly modulates KIR2DL4-mediated responses. J Immunol 2013;191:5256-5267.
    • (2013) J Immunol , vol.191 , pp. 5256-5267
    • Brusilovsky, M.1
  • 115
    • 0035881573 scopus 로고    scopus 로고
    • Cutting edge: induction of ifn-gamma production but not cytotoxicity by the killer cell ig-like receptor kir2dl4 (cd158d) in resting nk cells
    • Rajagopalan S, Fu J, Long EO. Cutting edge: induction of ifn-gamma production but not cytotoxicity by the killer cell ig-like receptor kir2dl4 (cd158d) in resting nk cells. J Immunol 2001;167:1877-1881.
    • (2001) J Immunol , vol.167 , pp. 1877-1881
    • Rajagopalan, S.1    Fu, J.2    Long, E.O.3
  • 116
    • 33947669011 scopus 로고    scopus 로고
    • Human KIR2DL5 is an inhibitory receptor expressed on the surface of NK and T lymphocyte subsets
    • Estefania E, Flores R, Gomez-Lozano N, Aguilar H, Lopez-Botet M, Vilches C. Human KIR2DL5 is an inhibitory receptor expressed on the surface of NK and T lymphocyte subsets. J Immunol 2007;178:4402-4410.
    • (2007) J Immunol , vol.178 , pp. 4402-4410
    • Estefania, E.1    Flores, R.2    Gomez-Lozano, N.3    Aguilar, H.4    Lopez-Botet, M.5    Vilches, C.6
  • 117
    • 0027959069 scopus 로고
    • NK3-specific natural killer cells are selectively inhibited by Bw4- positive HLA alleles with isoleucine 80
    • Cella M, Longo A, Ferrara GB, Strominger JL, Colonna M. NK3-specific natural killer cells are selectively inhibited by Bw4- positive HLA alleles with isoleucine 80. J Exp Med 1994;180:1235-1242.
    • (1994) J Exp Med , vol.180 , pp. 1235-1242
    • Cella, M.1    Longo, A.2    Ferrara, G.B.3    Strominger, J.L.4    Colonna, M.5
  • 118
    • 0028332836 scopus 로고
    • NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules
    • Litwin V, Gumperz J, Parham P, Phillips JH, Lanier LL. NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules. J Exp Med 1994;180:537-543.
    • (1994) J Exp Med , vol.180 , pp. 537-543
    • Litwin, V.1    Gumperz, J.2    Parham, P.3    Phillips, J.H.4    Lanier, L.L.5
  • 120
    • 77955272566 scopus 로고    scopus 로고
    • A novel KIR-associated function: evidence that CpG DNA uptake and shuttling to early endosomes is mediated by KIR3DL2
    • Sivori S, et al. A novel KIR-associated function: evidence that CpG DNA uptake and shuttling to early endosomes is mediated by KIR3DL2. Blood 2010;116:1637-1647.
    • (2010) Blood , vol.116 , pp. 1637-1647
    • Sivori, S.1
  • 121
    • 10144227765 scopus 로고    scopus 로고
    • The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer
    • Pende D, et al. The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer. J Exp Med 1996;184:505-518.
    • (1996) J Exp Med , vol.184 , pp. 505-518
    • Pende, D.1
  • 122
    • 0025267879 scopus 로고
    • + natural killer cells. Role in cell activation and regulation of cytolytic function
    • + natural killer cells. Role in cell activation and regulation of cytolytic function. J Exp Med 1990;171:695-714.
    • (1990) J Exp Med , vol.171 , pp. 695-714
    • Moretta, A.1
  • 123
    • 77956218914 scopus 로고    scopus 로고
    • Combined genotypic and phenotypic killer cell Ig-like receptor analyses reveal KIR2DL3 alleles displaying unexpected monoclonal antibody reactivity: identification of the amino acid residues critical for staining
    • Falco M, et al. Combined genotypic and phenotypic killer cell Ig-like receptor analyses reveal KIR2DL3 alleles displaying unexpected monoclonal antibody reactivity: identification of the amino acid residues critical for staining. J Immunol 2010;185:433-441.
    • (2010) J Immunol , vol.185 , pp. 433-441
    • Falco, M.1
  • 124
    • 84894339689 scopus 로고    scopus 로고
    • Activating killer cell immunoglobulin-like receptor 2DS2 binds to HLA-A*11
    • Liu J, Xiao Z, Ko HL, Shen M, Ren EC. Activating killer cell immunoglobulin-like receptor 2DS2 binds to HLA-A*11. Proc Natl Acad Sci USA 2014;111:2662-2667.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 2662-2667
    • Liu, J.1    Xiao, Z.2    Ko, H.L.3    Shen, M.4    Ren, E.C.5
  • 125
    • 33846200446 scopus 로고    scopus 로고
    • Cutting edge: KIR3DS1, a gene implicated in resistance to progression to AIDS, encodes a DAP12-associated receptor expressed on NK cells that triggers NK cell activation
    • Carr WH, Rosen DB, Arase H, Nixon DF, Michaelsson J, Lanier LL. Cutting edge: KIR3DS1, a gene implicated in resistance to progression to AIDS, encodes a DAP12-associated receptor expressed on NK cells that triggers NK cell activation. J Immunol 2007;178:647-651.
    • (2007) J Immunol , vol.178 , pp. 647-651
    • Carr, W.H.1    Rosen, D.B.2    Arase, H.3    Nixon, D.F.4    Michaelsson, J.5    Lanier, L.L.6
  • 126
    • 84928579211 scopus 로고    scopus 로고
    • Peptide-dependent recognition of HLA-B*57:01 by KIR3DS1
    • O'Connor GM, et al. Peptide-dependent recognition of HLA-B*57:01 by KIR3DS1. J Virol 2015;89:5213-5221.
    • (2015) J Virol , vol.89 , pp. 5213-5221
    • O'Connor, G.M.1
  • 127
    • 5844318282 scopus 로고    scopus 로고
    • Physical and functional independency of p70 and p58 natural killer (NK) cell receptors for HLA class I: their role in the definition of different groups of alloreactive NK cell clones
    • Vitale M, et al. Physical and functional independency of p70 and p58 natural killer (NK) cell receptors for HLA class I: their role in the definition of different groups of alloreactive NK cell clones. Proc Natl Acad Sci USA 1996;93:1453-1457.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1453-1457
    • Vitale, M.1
  • 128
    • 0032574781 scopus 로고    scopus 로고
    • HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A
    • Lee N, et al. HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A. Proc Natl Acad Sci USA 1998;95:5199-5204.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 5199-5204
    • Lee, N.1
  • 129
    • 0029837084 scopus 로고    scopus 로고
    • Inhibitory CD94 molecules identified by the Z199 monoclonal antibody recognize different HLA-class I molecules
    • Sivori S, et al. Inhibitory CD94 molecules identified by the Z199 monoclonal antibody recognize different HLA-class I molecules. Transpl Proc 1996;28:3199-3203.
    • (1996) Transpl Proc , vol.28 , pp. 3199-3203
    • Sivori, S.1
  • 130
    • 0033229761 scopus 로고    scopus 로고
    • The inhibitory receptor LIR-1 uses a common binding interaction to recognize class I MHC molecules and the viral homolog UL18
    • Chapman TL, Heikeman AP, Bjorkman PJ. The inhibitory receptor LIR-1 uses a common binding interaction to recognize class I MHC molecules and the viral homolog UL18. Immunity 1999;11:603-613.
    • (1999) Immunity , vol.11 , pp. 603-613
    • Chapman, T.L.1    Heikeman, A.P.2    Bjorkman, P.J.3
  • 131
    • 0031772638 scopus 로고    scopus 로고
    • The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes
    • Fanger NA, Cosman D, Peterson L, Braddy SC, Maliszewski CR, Borges L. The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes. Eur J Immunol 1998;28:3423-3434.
    • (1998) Eur J Immunol , vol.28 , pp. 3423-3434
    • Fanger, N.A.1    Cosman, D.2    Peterson, L.3    Braddy, S.C.4    Maliszewski, C.R.5    Borges, L.6
  • 132
    • 0025913857 scopus 로고
    • A 72-kD B cell-associated surface glycoprotein expressed at high levels in hairy cell leukaemia and plasma cell neoplasms
    • Pulford K, Micklem K, Thomas J, Jones M, Mason DY. A 72-kD B cell-associated surface glycoprotein expressed at high levels in hairy cell leukaemia and plasma cell neoplasms. Clin Exp Immunol 1991;85:429-435.
    • (1991) Clin Exp Immunol , vol.85 , pp. 429-435
    • Pulford, K.1    Micklem, K.2    Thomas, J.3    Jones, M.4    Mason, D.Y.5
  • 133
    • 35148833569 scopus 로고    scopus 로고
    • Facilitation of KIR genotyping by a PCR-SSP method that amplifies short DNA fragments
    • Vilches C, Castano J, Gomez-Lozano N, Estefania E. Facilitation of KIR genotyping by a PCR-SSP method that amplifies short DNA fragments. Tissue Antigens 2007;70:415-422.
    • (2007) Tissue Antigens , vol.70 , pp. 415-422
    • Vilches, C.1    Castano, J.2    Gomez-Lozano, N.3    Estefania, E.4
  • 134
    • 34447545481 scopus 로고    scopus 로고
    • A homodimeric complex of HLA-G on normal trophoblast cells modulates antigen-presenting cells via LILRB1
    • Apps R, Gardner L, Sharkey AM, Holmes N, Moffett A. A homodimeric complex of HLA-G on normal trophoblast cells modulates antigen-presenting cells via LILRB1. Eur J Immunol 2007;37:1924-1937.
    • (2007) Eur J Immunol , vol.37 , pp. 1924-1937
    • Apps, R.1    Gardner, L.2    Sharkey, A.M.3    Holmes, N.4    Moffett, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.