Co-evolution of KIR2DL3 with HLA-C in a human population retaining minimal essential diversity of KIR and HLA class I ligands

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 44, 2009, Pages 18692-18697

  Gendzekhadze, Ketevan ^a   Norman, Paul J ^a   Abi Rached, Laurent ^a   Graef, Thorsten ^a   Moesta, Achim K ^a   Layrisse, Zulay ^b   Parham, Peter ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

Author keywords

Amerindian; Immune diversity; Natural selection; NK cells; Reproduction

Indexed keywords

HLA ANTIGEN CLASS 1; HLA C ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL3;

ARTICLE; CONTROLLED STUDY; GENE FREQUENCY; HAPLOTYPE; HOMOZYGOSITY; HUMAN; IMMUNITY; MAJOR CLINICAL STUDY; NATURAL KILLER CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS HEPATITIS;

ALLELES; EPITOPES; EVOLUTION, MOLECULAR; GENETIC VARIATION; HAPLOTYPES; HLA-C ANTIGENS; HUMANS; INDIANS, SOUTH AMERICAN; LIGANDS; MOLECULAR SEQUENCE DATA; MUTATION; RECEPTORS, KIR2DL3; SELECTION, GENETIC;

EID: 73249146908     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0906051106     Document Type: Article

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