CMV drives clonal expansion of NKG2C + NK cells expressing self-specific KIRs in chronic hepatitis patients

European Journal of Immunology

Volumn 42, Issue 2, 2012, Pages 447-457

  Béziat, Vivien ^a,b,c   Dalgard, Olav ^d,e   Asselah, Tarik ^d   Halfon, Philippe ^f   Bedossa, Pierre ^d   Boudifa, Ali ^g   Hervier, Baptiste ^a,b   Theodorou, Ioannis ^b,g   Martinot, Michelle ^d   Debré, Patrice ^a,b,g   Björkström, Niklas K ^c   Malmberg, Karl Johan ^c   Marcellin, Patrick ^d   Vieillard, Vincent ^a,b  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d BEAUJON HOSPITAL   (France)

^e OSLO UNIVERSITY HOSPITAL   (Norway)

^f Hospital Ambroise Pare   (France)

^g Laboratoire d'Immunologie Cellulaire et Tissulaire CNRS URA 625   (France)

Author keywords

CMV; HBV; HCV; KIR; Natural killer cells; NK cell education; NKG2C

Indexed keywords

CD56 ANTIGEN; GAMMA INTERFERON; GRANZYME A; GRANZYME B; GRANZYME K; HLA ANTIGEN CLASS 1; HLA E ANTIGEN; INTERLEUKIN 12; INTERLEUKIN 18; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL2; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL3; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; PERFORIN; PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CELL EXPANSION; CONTROLLED STUDY; CYTOMEGALOVIRUS; FEMALE; FLOW CYTOMETRY; HEPATITIS B; HEPATITIS C; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; NATURAL KILLER CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; ANTIBODIES, VIRAL; ANTIGENS, CD56; AUTOANTIGENS; CELL DIFFERENTIATION; CELL GROWTH PROCESSES; CELLS, CULTURED; CLONAL SELECTION, ANTIGEN-MEDIATED; CYTOKINES; CYTOMEGALOVIRUS; FEMALE; GENE EXPRESSION REGULATION; HEPATITIS, CHRONIC; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; KILLER CELLS, NATURAL; LYMPHOCYTE SUBSETS; MALE; MIDDLE AGED; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY C; RECEPTORS, KIR2DL2;

EID: 84856055597     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201141826     Document Type: Article

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