Genome-wide siRNA screen reveals a new cellular partner of NK cell receptor KIR2DL4: Heparan sulfate directly modulates KIR2DL4-mediated responses

Journal of Immunology

Volumn 191, Issue 10, 2013, Pages 5256-5267

  Brusilovsky, Michael ^a   Cordoba, Moti ^a   Rosental, Benyamin ^a   Hershkovitz, Oren ^a   Andrake, Mark D ^b   Pecherskaya, Anna ^b   Einarson, Margret B ^b   Zhou, Yan ^b   Braiman, Alex ^a   Campbell, Kerry S ^b   Porgador, Angel ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD56 ANTIGEN; GLUCOSAMINE 3 O SULFOTRANSFERASE 3B1; HEPARAN SULFATE; HLA G ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL4; LIGAND; NATURAL KILLER CELL RECEPTOR; PROTEOHEPARAN SULFATE; RAB PROTEIN; RAB7 PROTEIN; SMALL INTERFERING RNA; SULFOTRANSFERASE; SYNDECAN 4; UNCLASSIFIED DRUG; HEPARIN; HEPARITIN SULFOTRANSFERASE; KIR2DL4 PROTEIN, HUMAN; MONOCLONAL ANTIBODY; SDC4 PROTEIN, HUMAN;

ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN FUNCTION; ANTIGEN RECOGNITION; ARTICLE; CELL MIGRATION; CELL STRAIN HEK293; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEGRADATION; DOWN REGULATION; EMBRYO; ENDOCYTOSIS; ENDOSOME; FEMALE; FETUS; GENETIC ASSOCIATION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MALE; NATURAL KILLER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; ANIMAL; CELL LINE; CHO CELL LINE; CRICETULUS; GENETICS; HEK293 CELL LINE; IMMUNOLOGY; METABOLISM; PROTEIN TERTIARY STRUCTURE; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE; CHO CELLS; CRICETULUS; ENDOCYTOSIS; HEK293 CELLS; HEPARIN; HEPARITIN SULFATE; HUMANS; KILLER CELLS, NATURAL; PROTEIN STRUCTURE, TERTIARY; RAB GTP-BINDING PROTEINS; RAB5 GTP-BINDING PROTEINS; RECEPTORS, KIR2DL4; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SULFOTRANSFERASES; SYNDECAN-4;

EID: 84887494494     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1302079     Document Type: Article

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