Mutation at positively selected positions in the binding site for HLA-C shows that KIR2DL1 Is a more refined but less adaptable NK cell receptor than KIR2DL3

Journal of Immunology

Volumn 189, Issue 3, 2012, Pages 1418-1430

  Hilton, Hugo G ^a   Vago, Luca ^a,b   Older Aguilar, Anastazia M ^a   Moesta, Achim K ^a   Graef, Thorsten ^a   Abi Rached, Laurent ^a   Norman, Paul J ^a   Guethlein, Lisbeth A ^a   Fleischhauer, Katharina ^b   Parham, Peter ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HLA A ANTIGEN; HLA B ANTIGEN; HLA C ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL3;

ANIMAL CELL; ANTIGEN BINDING; ARTICLE; BINDING SITE; CELL LINE; CONTROLLED STUDY; CROSS REACTION; HUMAN; HUMAN CELL; LYMPHOCYTE FUNCTION; MUTANT; NATURAL KILLER CELL; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; GENETIC VARIATION; HLA-C ANTIGENS; HUMANS; KILLER CELLS, NATURAL; POINT MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, KIR2DL1; RECEPTORS, KIR2DL3;

EID: 84864148132     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100431     Document Type: Article

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