Altered Expression of Ly49 Inhibitory Receptors on Natural Killer Cells from MHC Class I-Deficient Mice

Journal of Immunology

Volumn 158, Issue 7, 1997, Pages 3174-3180

  Salcedo, Margarita ^a   Diehl, Alexander D ^a   Olsson Alheim, Mats Y ^a   Sundbäck, Jonas ^a   Van Kaer, Luc ^b   Kärre, Klas ^a   Ljunggren, Hans Gustaf ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; H2 ANTIGEN; IMMUNOGLOBULIN RECEPTOR; LECTIN; LY 49 ANTIGEN; LY ANTIGEN; LY-49 ANTIGEN; MEMBRANE ANTIGEN; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY;

ANIMAL; ANTIBODY AFFINITY; ARTICLE; BIOSYNTHESIS; CHEMISTRY; CLASSIFICATION; GENETICS; IMMUNOLOGY; LYMPHOCYTE COUNT; METABOLISM; MOUSE; NATURAL KILLER CELL; TRANSGENIC MOUSE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; ANTIGENS, LY; ANTIGENS, SURFACE; CARRIER PROTEINS; H-2 ANTIGENS; KILLER CELLS, NATURAL; LECTINS, C-TYPE; LYMPHOCYTE COUNT; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; RECEPTORS, IMMUNOLOGIC;

EID: 0031110365     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Trinchieri, G. 1989. Biology of natural killer cells. Adv. Immunol. 47:187.
2. Kärre, K., H. G. Ljunggren, G. E. Piontek, and R. Kiessling. 1986. Selective rejection of H-2 deficient lymphoma variants suggests alternative immune defence strategy. Nature 319:675.
3. Ljunggren, H. G., and K. Kärre. 1990. In search of the 'missing self.' MHC molecules and NK cell recognition. Immunol. Today 11:237.
4. Gumperz, J. E., and P. Parham. 1995. The enigma of the natural killer cell. Nature 378:245.
5. Ljunggren, H. G., and K. Kärre. 1985. Host resistance directed selectively against H-2-deficient lymphoma variants: analysis of the mechanism. J. Exp. Med. 162: 1745.
6. Harel-Bellan, A., A. Quillet, C. Marchiol, R. DeMars, T. Tursz, and D. Fradelizi, 1986. Natural killer susceptibility of human cells may be regulated by genes in the HLA region on chromosome 6. Proc. Natl. Acad. Sci. USA 83:5688.
7. Storkus, W. J., D. N. Howell, R. D. Salter, J. R. Dawson, and P. Cresswell. 1987. NK susceptibility varies inversely with target cell class I HLA antigen expression. J. Immunol. 138:1657.
8. Storkus, W. J., J. Alexander, J. A. Payne, J. R. Dawson, and P. Cresswell. 1989. Reversal of natural killing susceptibility in target cells expressing transfected class I HLA genes. Proc. Natl. Acad. Sci. USA 86:2361.
9. Bix, M., N.-S. Liao, M. Zijlstra, J. Loring, R. Jaenisch, and D. Raulet. 1991. Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice. Nature 349:329.
10. Liao, N. S., M. Bix, M. Zijlstra, R. Jaenisch, and D. Raulet. 1991. MHC class I deficiency: susceptibility to natural killer (NK) cells and impaired NK activity. Science 253:199.
11. - bone marrow in chimeric mice. Proc. Natl. Acad. Sci. USA 88:10332.
12. Ljunggren, H. G., L. Van Kaer, H. L. Ploegh, and S. Tonegawa. 1994. Altered natural killer cell repertoire in TAP1 mutant mice, Proc. Natl. Acad. Sci. USA 91:6520.
13. + IL-2-activated natural killer cells. Nature 358: 66.
14. Larnier, L. L., and J. H. Phillips. 1996. Inhibitory MHC class I receptors on NK cells and T cells. Immunol. Today 17:86.
15. Raulet, D. H. 1996. Recognition events that inhibit and activate natural killer cells. Curr. Opin. Immunol. 8:372.
16. Colonna, M. 1996. Natural killer receptors specific for MHC class I molecules. Curr. Opin. Immunol. 8:101.
17. Moretta, A., C. Bottino, M. Vitale, D. Pende, R. Biassoni, M. C. Mingari, and L. Moretta. 1996. Receptors for HLA class-1 molecules in human natural killer cells. Annu. Rev. Immunol. 14:619.
18. Yokoyama, W. M., P. A. Kehn, D. I. Cohen, and E. M. Shevach. 1990. Chromosomal location of the Ly-49 (Al, YE1/48) mulligene family: genetic association with the NK1.1 antigen. J. Immunol. 145:2353.
19. Wong, S., J. D. Freeman, C. Kelleher, D. Mager, and F. Takei. 1991. Ly-49 multigene family: new members of a superfamily of type II membrane proteins with lectin-like domains. J. Immunol. 147:1417.
20. Smith, H. R. C., F. M. Karlhofer, and W. M. Yokoyama. 1994. Ly-49 multigene family expressed by IL-2 activated NK cells. J. Immunol. 153:1068.
21. Brennan, J., D. Mager, W. Jefferies, and F. Takei. 1994. Expression of different members of the Ly-49 gene family defines distinct natural killer cell subsets and cell adhesion properties. J. Exp. Med. 180:2287.
22. Yokoyama, W. M., and W. E. Seaman. 1993. The Ly-49 and NKR-P1 gene families encoding lectin like receptors on natural killer cells: the NK gene complex. Annu. Rev. Immunol. 11:613.
23. Chan, P.-Y., and F. Takei. 1986. Expression of a T cell receptor-like molecule on normal and malignant murine T cells detected by rat monoclonal antibodies to nonclonotypic determinants. J. Immunol. 136:1346.
24. Roland, J., and P. A. Cazenave. 1992. Ly-49 antigen defines an alpha beta TCR population in i-IEL with an extrathymic maturation. Int. Immunol. 4:699.
25. b bone marrow grafts. J. Exp. Med. 170:191.
26. Mason, L. H., J. R. Ortaldo, H. A. Young, V. Kumar, M. Bennett, and S. K. Anderson. 1995. Cloning and functional characteristics of murine large granular lymphocyte-1: a member of the Ly-49 gene family (Ly-49G2). J. Exp. Med. 182:293.
27. Yu, Y. Y. L., T. George, J. R. Dorfman, J. Roland, V. Kumar, and M. Bennett. 1996. The role of Ly49A and 5E6 (Ly49C) molecules in hybrid resistance mediated by murine natural killer cells against normal T cell blasts. Immunity 4:67.
28. Brennan, J., G. Mahon, D. L. Mager, W. A. Jefferies, and F. Takei. 1996. Recognition of class I major histocompatibility complex molecules by Ly-49: specificities and domain interactions. J. Exp. Med. 183:1553.
29. d transgene to C57BL mice. J. Exp. Med. 168:1469.
30. Öhlén, C., G. Kling, P. Höglund, M. Hansson, G. Scangos, C. Bieberich, G. Jay, and K. Kärre. 1989. Prevention of allogeneic bone marrow graft by H-2 transgene in donor mice. Science 246:666.
31. Sykes, M., M. W. Harty, F. M. Karlhofer, D. A. Pearson, G. Szot, and W. Yokoyama. 1993. Hematopoietic cells and radioresistant host elements influence natural killer cell differentiation. J. Exp. Med. 178:223.
32. Karlhofer, F. M., R. Hunziker, A. Reichlin, D. H. Margulies, and W. M. Yokoyama. 1994. Host MHC class I modulate in vivo expression of a natural killer cell receptor. J. Immunol. 153:2407.
33. Olsson, M. Y., K. Kärre, and C. L. Sentman. 1995. Altered phenotype and function of natural killer cells expressing the major histocompatibility complex receptor Ly-49 in mice transgenic for its ligand. Proc. Natl. Acad. Sci. USA 92:1649.
34. Dorfman, J. R., and D. H. Raulet. 1996. Major histocompatibility complex genes determine natural killer cell tolerance. Eur. J. Immunol. 26:151.
35. Sundbäck, J., K. Kärre, and C. L. Sentman. 1996. Cloning of minimally divergent allelic forms of the NK receptor Ly49-C, differentially controlled by host genes in the MHC and NK gene complexes. J. Immunol. 157:3936.
36. Bieberich, C, G. Skangos, K. Tanaka, and G. Jay. 1986. Regulated expression of a murine class I gene in transgenic mice. Mol. Cell. Biol. 6:1339.
37. + T cells. Science 248:1227.
38. -+ T cells. Cell 71:1205.
39. 2-microglobulin double mutant mice. Int. Immunol. 7:975.
40. Nagasawa, R., J. Gross, O. Kanagawa, K. Townsend, L. L. Lanier, J. Chiller, and J. P. Allison. 1987. Identification of a novel T cell surface disulfide-bonded dimer distinct from the αβ antigen receptor. J. Immunol. 138:815.
41. Sentman, C. L., J. Hackett, Jr., T. A. Moore, M. M. Tutt, M. Bennett, and V. Kumar. 1989. Pan natural killer cell monoclonal antibodies and their relationship to the NK1.1 antigen. Hybridoma 8:605.
42. Koo, G. C., and J. R. Peppard. 1984. Establishment of monoclonal anti NK1.1 antibody. Hybridoma 3:101.
43. Kane, K. P. 1994. Ly-49 mediates EL-4 lymphoma adhesion to isolated class I major histocompatibility complex molecules. J. Exp. Med. 179:1011.
44. Daniels, B. F., F. M. Karlhofer, W. E. Seaman, and W. M. Yokoyama. 1994. A natural killer receptor specific for a major histocompatibility complex class I molecule. J. Exp. Med. 180:687.
45. Held, W., J. Roland, and D. H. Raulet. 1995. Allelic exclusion of Ly-49 family genes encoding class I MHC-specitic receptors on NK cells. Nature 376:355.
46. Sentman, C. L., M. Y. Olsson, and K. Kärre. 1995. Missing self recognition by natural killer cells in MHC class I transgenic mice: a 'receptor calibration' model for how effector cells adapt to self. Semin. Immunol. 7:109.
47. 1 hybrid and missing self situation. In MHC Antigens and NK Cell Recognition. R. Solana, and J. Peña, eds. CRC Press, Boca Raton, p. 104.
48. Held, W., J. R. Dorfman, M. F. Wu, and D. H. Raulet. 1996. Major histocompatibility complex class I-dependent skewing of the natural killer cell Ly49 receptor repertoire. Eur. J. Immunol. 26:2286.
49. Brennan J., S. Lemieux, J. D. Freeman, D. L. Mager, and F. Takei. 1996. Heterogeneity among Ly49C natural killer cells: characterization of highly related receptors with differing functions and expression patterns. J. Exp. Med. 184:2085.